Aliases for PPFIBP2 Gene
External Ids for PPFIBP2 Gene
Previous GeneCards Identifiers for PPFIBP2 Gene
This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
GeneCards Summary for PPFIBP2 Gene
PPFIBP2 (PTPRF Interacting Protein, Binding Protein 2 (Liprin Beta 2)) is a Protein Coding gene. Diseases associated with PPFIBP2 include bile duct adenocarcinoma. GO annotations related to this gene include integrase activity. An important paralog of this gene is KAZN.
UniProtKB/Swiss-Prot for PPFIBP2 Gene
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.