Aliases for PPCS Gene
External Ids for PPCS Gene
Previous GeneCards Identifiers for PPCS Gene
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 126.96.36.199), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]
GeneCards Summary for PPCS Gene
PPCS (Phosphopantothenoylcysteine Synthetase) is a Protein Coding gene. Diseases associated with PPCS include Pleural Disease. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include phosphopantothenate--cysteine ligase activity.
UniProtKB/Swiss-Prot for PPCS Gene
Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4-phosphopantothenate to form 4-phosphopantothenoylcysteine.