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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PPAPDC3 Gene

protein-coding GIFtS: 45
GCID: GC09P134165

phosphatidic acid phosphatase type 2 domain containing 3

(Previous name: chromosome 9 open reading frame 67 )
(Previous symbol: C9orf67)

Search for PPAPDC3
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Phosphatidic Acid Phosphatase Type 2 Domain Containing 3¹ ²		MGC12921¹
C9orf67¹ ² ³		Chromosome 9 Open Reading Frame 67¹
NET39¹ ²		Probable Lipid Phosphate Phosphatase PPAPDC3²
Phosphatidic Acid Phosphatase Type 2 Domain-Containing Protein 3² ³		EC 3.1.3.-³
FLJ14662¹		EC 3.1.3⁸

External Ids:	HGNC: 28174¹	Entrez Gene: 84814²	Ensembl: ENSG00000160539⁷	UniProtKB: Q8NBV4³

Export aliases for PPAPDC3 gene to outside databases

Previous GC identifers: GC09P131195 GC09P133154 GC09P103655

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PPAC3_HUMAN, Q8NBV4

Function: Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling.

Has no detectable enzymatic activity (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_035014.4

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PPAPDC3 gene promoter:
STAT5B RelA Nkx2-5 Meis-1b GATA-1 POU2F1 Zic1 POU2F1a Meis-1a Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PPAPDC3 promoter sequence

Search SABiosciences Chromatin IP Primers for PPAPDC3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPAPDC3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13 Ensembl cytogenetic band: 9q34.13 HGNC cytogenetic band: 9q34.2-q34.3

PPAPDC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPAPDC3 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09P134165: view genomic region (about GC identifiers)

Start:	134,165,081 bp from pter	End:	134,184,649 bp from pter
Size:	19,569 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PPAC3_HUMAN, Q8NBV4 (See protein sequence)

Recommended Name: Probable lipid phosphate phosphatase PPAPDC3

Size: 271 amino acids; 29448 Da

Subunit: Homo and heterooligomer. Interacts with MTOR; controls MTOR-dependent IGF2 expression during myoblast

differentiation (By similarity)

Subcellular location: Nucleus envelope. Endoplasmic reticulum membrane. Membrane; Multi-pass membrane protein.

Note=Both the N- and C-terminal are exposed to the cytoplasm/nucleoplasm (By similarity)

Sequence caution: Sequence=CAI16274.1; Type=Erroneous gene model prediction;

Secondary accessions: Q5T6P0 Q96SS7 Q9BRC3

Explore the universe of human proteins at neXtProt for PPAPDC3: NX_Q8NBV4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NBV4

4/5 DME Specific Peptides for PPAPDC3 (Q8NBV4) (see all 5)

RNNVLNR

HLVLAVPLR

NLLLALLLD

LPEEDCMQLNPSFKGIA

PPAPDC3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_116117.3

ENSEMBL proteins:

ENSP00000361338 ENSP00000361335

Human Recombinant Protein Products:

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	Novus Biologicals PPAPDC3 Proteins
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for PPAPDC3

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005635	nuclear envelope	IEA	--
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

PPAPDC3 for ontologies About GeneDecksing

PPAPDC3 Antibody Products:

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	Novus Biologicals PPAPDC3 Antibodies
	Search for Antibodies for PPAPDC3 at Abcam
	Uscn Antibodies for PPAPDC3
	ThermoFisher Antibodies for PPAPDC3

Assay Products for PPAPDC3:

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	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for PPAPDC3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for PPAPDC3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PPAPDC3 for domains About GeneDecksing

2 InterPro domains/families:

IPR000326 P_Acid_Pase_2/haloperoxidase

IPR016118 P_Acid_Pase/Cl_peroxidase_N

Graphical View of Domain Structure for InterPro Entry Q8NBV4

ProtoNet protein and cluster: Q8NBV4

1 Blocks protein family: IPB000326 PA-phosphatase related phosphoesterase

UniProtKB/Swiss-Prot: PPAC3_HUMAN, Q8NBV4

Similarity: Belongs to the PA-phosphatase related phosphoesterase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: PPAC3_HUMAN, Q8NBV4

Function: Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling.

Has no detectable enzymatic activity (By similarity)

Enzyme Numbers (IUBMB): EC 3.1.3² EC 3.1.3.-¹

miRNA Products:		OriGene 3'-UTR Clone: PPAPDC3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPAPDC3
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate PPAPDC3 (see all 9):
		hsa-miR-331-3p hsa-miR-512-3p hsa-miR-3926 hsa-miR-890 hsa-miR-2355-5p hsa-miR-637 hsa-miR-3915 hsa-miR-18b*

		SwitchGear 3'UTR luciferase reporter plasmid: PPAPDC3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPAPDC3 (see all 7) OriGene shRNA RFP: PPAPDC3 OriGene siRNA: PPAPDC3
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for PPAPDC3

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		GenScript: all cDNA clones in your preferred vector: PPAPDC3 (NM_032728)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for PPAPDC3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPAPDC3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for PPAPDC3
		Search LifeMap BioReagents cell lines for PPAPDC3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPAPDC3

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016787	hydrolase activity	IEA	--

PPAPDC3 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PPAPDC3

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0010832	negative regulation of myotube differentiation	IEA	--

PPAPDC3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PPAPDC3

10/12 HMDB Compounds for PPAPDC3 (see all 12) About this table

Compound	Synonyms	CAS #	PubMed Ids
PA(16:0/16:0)	Dipalmitoylphosphatidic acid (see all 25)	7091-44-3	--
PA(16:0/18:1(11Z))	PA(16:0/18:1n7) (see all 10)	--	--
PA(16:0/18:1(9Z))	PA(16:0/18:1n9) (see all 10)	--	--
PA(16:0/18:2(9Z,12Z))	PA(34:2) (see all 10)	--	--
PA(16:0e/18:0)	2-octadecanoyl-1-hexadecyl-sn-glycero-3-phosphate ;PA(o-16:0/18:0)	--	--
PA(18:0/18:2(9Z,12Z))	PA(36:2) (see all 10)	--	--
PA(18:1(11Z)/18:1(11Z))	PA(36:2) (see all 10)	--	--
PA(18:1(11Z)/18:1(9Z))	PA(36:2) (see all 10)	--	--
PA(18:1(9Z)/18:1(11Z))	PA(36:2) (see all 10)	--	--
PA(18:1(9Z)/18:1(9Z))	PA(36:2) (see all 10)	14268-17-8	--

Search CenterWatch for drugs/clinical trials and news about PPAPDC3 / PPAC3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PPAPDC3 gene:

NM_032728.3

Unigene Cluster for PPAPDC3:

Phosphatidic acid phosphatase type 2 domain containing 3

Hs.134292 [show with all ESTs]

Unigene Representative Sequence: NM_032728

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000372264(uc004cal.2) ENST00000372261

miRNA Products:		OriGene 3'-UTR Clone: PPAPDC3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPAPDC3
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate PPAPDC3 (see all 9):
		hsa-miR-331-3p hsa-miR-512-3p hsa-miR-3926 hsa-miR-890 hsa-miR-2355-5p hsa-miR-637 hsa-miR-3915 hsa-miR-18b*

		SwitchGear 3'UTR luciferase reporter plasmid: PPAPDC3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPAPDC3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPAPDC3 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: PPAPDC3 (NM_032728)
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPAPDC3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPAPDC3

Additional cDNA sequence:

AK027568.1 AK075207.1 AK315502.1 BC006362.2

3 DOTS entries:

DT.435078 DT.99973189 DT.95265837

24/66 AceView cDNA sequences (see all 66):

BX375801 CR619561 CR599374 CB153464 CB155411 BI753398 BX416024 BE645947

BI199053 BM725135 AI074502 BM548051 AI686516 BQ069029 BX105368 CF132168

AL521001 BC006362 AI571344 F24751 BF338461 AI434409 AK075207 BM465908

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PPAPDC3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAATGGAAA

About this image

PPAPDC3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See PPAPDC3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PPAPDC3

SOURCE GeneReport for Unigene cluster: Hs.134292

SABiosciences Custom PCR Arrays for PPAPDC3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPAPDC3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPAPDC3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPAPDC3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for PPAPDC3 gene from 7/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ppapdc3^{1 , 5}	phosphatidic acid phosphatase type 2 domain containing more^{1, 5}	89.42(n)¹ 94.83(a)¹		2 (22.02 cM)⁵ 227721¹ NM_145521.3¹ NP_663496.1¹ 32095528⁵
chicken (Gallus gallus)	Aves	PPAPDC3¹	phosphatidic acid phosphatase type 2 domain containing more	78.97(n) 81.92(a)		417178 XM_415460.3 XP_415460.1
zebrafish (Danio rerio)	Actinopterygii	ppapdc3¹	phosphatidic acid phosphatase type 2 domain containing more	68.03(n) 68.03(a)		402958 NM_205660.1 NP_991223.1
fruit fly (Drosophila melanogaster)	Insecta	CG31717⁶	--	27(a)	1 → many	2L(10250737-10251714)
worm (Caenorhabditis elegans)	Secernentea	T13C5.6⁶	--	32(a)	1 → many	X(6206546-6207653)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT4G22550⁶	Phosphatidic acid phosphatase (PAP2) family protei...	24(a)	1 → many	4(11878137-11878920)
rice (Oryza sativa)	Liliopsida	--	phosphatase, putative, expressed	25(a)	1 → many	2(26791456-26793339)

ENSEMBL Gene Tree for PPAPDC3 (if available)
TreeFam Gene Tree for PPAPDC3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PPAPDC3 gene

PPAPDC2²

1 SIMAP similar gene for PPAPDC3 using alignment to 1 protein entry: PPAC3_HUMAN:

PPAPDC2

PPAPDC3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs146196217^1,2		--	134163109(+)	`GGAGCC/TGGACC`	1	--	us2k¹		0	--	--	--	--
rs184517391^1,2		--	134163245(+)	`ATAGAA/GAGCTC`	1	--	us2k¹		0	--	--	--	--
rs113204559^1,2	F	--	134163267(+)	`AGCTTG/ATACAC`	1	--	us2k¹		2		CSA	4
rs115675410^1,2	F,	--	134163272(+)	`ATACAC/TGCTCA`	1	--	us2k¹		1		WA	118
rs189185821^1,2		--	134163292(+)	`CCTGGA/CGTGCA`	1	--	us2k¹		0	--	--	--	--
rs11244355^1,2	C,H,	--	134163324(+)	`CCAGCC/TGTCTA`	1	--	us2k¹		4		NS EA	416
rs145308687^1,2		--	134163351(+)	`AGCACA/GTGTCA`	1	--	us2k¹		0	--	--	--	--
rs73545981^1,2	C,F,	--	134163389(+)	`GTCTCA/C/GCGGCC`	1	--	us2k¹		5		WA NA	244
rs73656111^1,2	C,F,	--	134163497(+)	`CCAGCC/TAGGGC`	1	--	us2k¹		3		WA	122
rs149196611^1,2		--	134163503(+)	`AGGGCA/GTCTGC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for PPAPDC3 (134165081 - 134184649 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PPAPDC3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPAPDC3

DNA2.0 Custom Variant and Variant Library Synthesis for PPAPDC3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for PPAPDC3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with PPAPDC3)

Utopia: connect your pdf to the dynamic
world of online information

Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)^{1, 2} Otsuki T....Isogai T. (2005)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)^{1, 2} Humphray S.J.... Dunham I. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Nuclear membrane proteins with potential disease links found by subtractive proteomics. (PubMed id 12958361)^{1, 3} Schirmer E.C....Gerace L. (2003)
Regulation of myoblast differentiation by the nuclear envelope protein NET39. (PubMed id 19704009)¹ Liu G.H....Gerace L. (2009)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84814	HGNC: 28174	AceView: C9orf67	Ensembl:ENSG00000160539	euGenes: HUgn84814
ECgene: PPAPDC3	H-InvDB: PPAPDC3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for PPAPDC3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for PPAPDC3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for PPAPDC3 gene:
Search GeneIP for patents involving PPAPDC3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	EMD Millipore Mono- and Polyclonal Antibodies for the study of PPAPDC3
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	OriGene Antibodies for PPAPDC3		OriGene shRNA RFP for PPAPDC3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPAPDC3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPAPDC3
	OriGene Protein Over-expression Lysate for PPAPDC3		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for PPAPDC3		OriGene 3'-UTR Clone for PPAPDC3
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	OriGene Custom Antibody Services for PPAPDC3		OriGene Custom Protein Services for PPAPDC3
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PPAPDC3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPAPDC3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPAPDC3
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPAPDC3
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPAPDC3

	GenScript Custom Purified and Recombinant Proteins Services for PPAPDC3		GenScript cDNA clones with any tag delivered in your preferred vector for PPAPDC3
	GenScript Custom Assay Services for PPAPDC3		GenScript Custom Superior Antibodies Services for PPAPDC3
	GenScript Custom overexpressing Cell Line Services for PPAPDC3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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	Regulatory tfbs in PPAPDC3 promoter
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PPAPDC3 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for PPAPDC3

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPAPDC3

	SwitchGear 3'UTR luciferase reporter plasmids for PPAPDC3
	SwitchGear Promoter luciferase reporter plasmids for PPAPDC3

ThermoFisher Antibodies for PPAPDC3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPAPDC3

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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PPAPDC3 Gene

phosphatidic acid phosphatase type 2 domain containing 3

Aliases
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Summaries
for PPAPDC3 gene

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Proteins
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Protein Domains /
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for PPAPDC3 gene

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Pathways & Interactions
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Orthologs
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PPAPDC3 Gene

phosphatidic acid phosphatase type 2 domain containing 3

Aliasesfor PPAPDC3 gene

Summariesfor PPAPDC3 gene

Genomic Viewsfor PPAPDC3 gene

Proteinsfor PPAPDC3 gene

Protein Domains /Familiesfor PPAPDC3 gene

Functionfor PPAPDC3 gene

Pathways & Interactionsfor PPAPDC3 gene

Drugs & Compoundsfor PPAPDC3 gene

Transcriptsfor PPAPDC3 gene

Expression for PPAPDC3 gene

Orthologsfor PPAPDC3 gene

Paralogsfor PPAPDC3 gene

Genomic Variantsfor PPAPDC3 gene

Disorders / Diseasesfor PPAPDC3 gene

Publicationsfor PPAPDC3 gene

External Searches for PPAPDC3 gene

Genome Databases showing PPAPDC3 gene

Other Databases showing PPAPDC3 gene

Specialized Databases showing PPAPDC3 gene

Intellectual Propertyfor PPAPDC3 gene

Productsfor PPAPDC3 gene

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Aliases
for PPAPDC3 gene

Summaries
for PPAPDC3 gene

Genomic Views
for PPAPDC3 gene

Proteins
for PPAPDC3 gene

Protein Domains /
Families
for PPAPDC3 gene

Function
for PPAPDC3 gene

Pathways & Interactions
for PPAPDC3 gene

Drugs & Compounds
for PPAPDC3 gene

Transcripts
for PPAPDC3 gene

Expression
for PPAPDC3 gene

Orthologs
for PPAPDC3 gene

Paralogs
for PPAPDC3 gene

Genomic Variants
for PPAPDC3 gene

Disorders / Diseases
for PPAPDC3 gene

Publications
for PPAPDC3 gene

Intellectual Property
for PPAPDC3 gene

Products
for PPAPDC3 gene