Aliases for PPAN Gene
External Ids for PPAN Gene
Previous GeneCards Identifiers for PPAN Gene
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010]
GeneCards Summary for PPAN Gene
PPAN (Peter Pan Homolog (Drosophila)) is a Protein Coding gene. Diseases associated with PPAN include kummell's disease and prolapse of female genital organ. GO annotations related to this gene include poly(A) RNA binding. An important paralog of this gene is PPAN-P2RY11.
UniProtKB/Swiss-Prot for PPAN Gene
May have a role in cell growth.