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POU6F2 Gene

protein-coding GIFtS: 52
GCID: GC07P039012

POU Class 6 Homeobox 2

(Previous names: POU domain, class 6, transcription factor 2)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
POU Class 6 Homeobox 2¹ ²		WT5² ⁵
POU Domain, Class 6, Transcription Factor 2¹ ²		WTSL² ⁵
Retina-Derived POU-Domain Factor-1¹ ²		Wilms Tumor Suppressor Locus²
Retina-Derived POU Domain Factor 1² ³		RPF1³
RPF-1² ³

External Ids:	HGNC: 21694¹	Entrez Gene: 11281²	Ensembl: ENSG00000106536⁷	OMIM: 609062⁵	UniProtKB: P78424³

Export aliases for POU6F2 gene to outside databases

Previous GC identifers: GC07P038787 GC07P038819

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for POU6F2 Gene:

This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding

domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA

binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The

POU family members are transcriptional regulators, many of which are known to control cell type-specific

differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition.

Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.(provided by

RefSeq, Oct 2009)

GeneCards Summary for POU6F2 Gene:

POU6F2 (POU class 6 homeobox 2) is a protein-coding gene. Diseases associated with POU6F2 include wilms tumor susceptibility-5, and wilms tumor, type 1. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO6F2_HUMAN, P78424

Function: Probable transcription factor likely to be involved in early steps in the differentiation of amacrine

and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000007.14 NC_018918.2 NT_007819.18

Regulatory elements:

Regulatory transcription factor binding sites in the POU6F2 gene promoter:
STAT5B ISGF-3 HOXA3 AML1a Nkx2-2 FOXD1 C/EBPalpha Gfi-1 FAC1 FOXO4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): POU6F2 promoter sequence

Search Chromatin IP Primers for POU6F2

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU6F2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p14.1 Ensembl cytogenetic band: 7p14.1 HGNC cytogenetic band: 7p14.1

POU6F2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU6F2 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P039012: view genomic region (about GC identifiers)

Start:	39,017,598 bp from pter	End:	39,532,694 bp from pter
Size:	515,097 bases	Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 39,055,332-39,542,296

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PO6F2_HUMAN, P78424 (See protein sequence)

Recommended Name: POU domain, class 6, transcription factor 2

Size: 691 amino acids; 73265 Da

Sequence caution: Sequence=AAB49727.1; Type=Erroneous gene model prediction; Sequence=AAB49728.1; Type=Erroneous

initiation; Note=Translation N-terminally extended; Sequence=AAS07475.1; Type=Erroneous initiation;

Note=Translation N-terminally extended; Sequence=EAL23992.1; Type=Erroneous gene model prediction;

Secondary accessions: A4D1W2 C4AMB9 P78425 Q75ME8 Q86UM6 Q9UDS7

Alternative splicing: 2 isoforms: P78424-1 P78424-2 (Major isoform)

Explore the universe of human proteins at neXtProt for POU6F2: NX_P78424

Explore proteomics data for POU6F2 at MOPED

See POU6F2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_001159490.1 NP_009183.3

ENSEMBL proteins:

ENSP00000384004 ENSP00000430514 ENSP00000409684 ENSP00000452911 ENSP00000453020

ENSP00000452633 ENSP00000475747 ENSP00000404868

POU6F2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

POU: Homeoboxes / POU class

Selected InterPro protein domains (see all 6):

IPR010982 Lambda_DNA-bd_dom

IPR013847 POU

IPR000327 POU_specific

IPR001356 Homeobox_dom

IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry P78424

ProtoNet protein and cluster: P78424

2 Blocks protein domains:

IPB000327 POU domain

IPB013847 POU

UniProtKB/Swiss-Prot: PO6F2_HUMAN, P78424

Similarity: Belongs to the POU transcription factor family. Class-6 subfamily

Similarity: Contains 1 homeobox DNA-binding domain

Similarity: Contains 1 POU-specific domain

POU6F2 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: PO6F2_HUMAN, P78424

Function: Probable transcription factor likely to be involved in early steps in the differentiation of amacrine

and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA

Gene Ontology (GO): 3 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	--	--
GO:0003700	sequence-specific DNA binding transcription factor activity	TAS	8601806
GO:0043565	sequence-specific DNA binding	IEA	--

POU6F2 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for POU6F2:

Increased gamma-H2AX phosphory

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Pou6f2):

normal

POU6F2 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Pou6f2^tm1Nat for POU6F2

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POU6F2

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genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for POU6F2

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU6F2

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

PO6F2_HUMAN, P78424: Nucleus (Probable)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	4

About this image

Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IC	8601806

POU6F2 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for POU6F2
Interactions:

Search GeneGlobe Interaction Network for POU6F2

1 Interacting protein for POU6F2 (P78424³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
POU6F1	Q14863³	I2D: score=1

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Gene Ontology (GO): 5 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-templated	TAS	8601806
GO:0006366	transcription from RNA polymerase II promoter	TAS	8601806
GO:0007402	ganglion mother cell fate determination	TAS	8601806
GO:0007417	central nervous system development	TAS	8601806
GO:0007601	visual perception	TAS	8601806

POU6F2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for POU6F2 (PO6F2)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for POU6F2 gene (2 alternative transcripts):

NM_001166018.1 NM_007252.3

Unigene Cluster for POU6F2:

POU class 6 homeobox 2

Hs.137106 [show with all ESTs]

Unigene Representative Sequence: NM_007252

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000403058(uc003thb.2 uc022acb.1) ENST00000518318 ENST00000517348(uc010kxo.3)

ENST00000451021 ENST00000524147 ENST00000520104 ENST00000559001 ENST00000464276

ENST00000416452 ENST00000426456

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		QuantiFast Probe-based Assays in human, mouse, rat POU6F2

Additional mRNA sequence: U91935.1

4 DOTS entries:

DT.97812925 DT.91693741 DT.402711 DT.91714277

18 AceView cDNA sequences:

BU741744 BM680332 NM_007252 BM724167 AI928867 BX108040 AW261867 BX646845

U91935 BM724588 AI252764 AI025567 AI929032 BF931113 AI761853 H08886

BF357653 BF831355

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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POU6F2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TCTCAAAGTC

About this image

POU6F2 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 4) fully expand


Neural Tube (Nervous System) fully expand to see all 2 entries
Spinal Ventral Columns

Eye (Sensory Organs)
Retina

Brain (Nervous System)
Medulla Oblongata

Larynx (Respiratory System)

POU6F2 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

POU6F2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.137106

UniProtKB/Swiss-Prot: PO6F2_HUMAN, P78424

Tissue specificity: Expressed only within the CNS, where its expression is restricted to the medical habenulla, to

a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in

the retina

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU6F2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for POU6F2 gene from Selected species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Pou6f2⁵	POU domain, class 6, transcription factor 2	--		13 (6.05 cM) 18121101
chicken (Gallus gallus)	Aves	POU6F2⁶	POU class 6 homeobox 2	85(a)	1 ↔ 1	2(50031906-50327049)
lizard (Anolis carolinensis)	Reptilia	-- --	Uncharacterized protein	80(a) 77(a)	1 ↔ many 1 ↔ many	6(48235250-48478489) 6(48684466-48703152)
zebrafish (Danio rerio)	Actinopterygii	pou6f2⁶	POU class 6 homeobox 2	70(a)	1 ↔ 1	24(9839895-10076387) ENSDARG00000086362
fruit fly (Drosophila melanogaster)	Insecta	pdm3⁶	pou domain motif 3	18(a)	1 ↔ 1	2R(4215005-4283785)

ENSEMBL Gene Tree for POU6F2 (if available)
TreeFam Gene Tree for POU6F2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for POU6F2 gene

POU5F2² POU4F2² POU2F3² POU3F1² POU3F4² POU1F1² POU3F3² POU4F3²

POU3F2² POU2F2² POU5F1B² POU4F1² POU2F1² POU6F1² POU5F1²

4 SIMAP similar genes for POU6F2 using alignment to 7 protein entries: PO6F2_HUMAN (see all proteins):

POU6F1 OCT6 OCT-2 POU1F1

POU6F2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
VAR_022419⁴		Hereditary susceptibility to Wilms tumor 5 (WT5)⁴	--	see VAR_022419	2	Q H	mis⁴		0	--	--	--	--
rs859540^1,2	C,F,O	--	38990913(-)	`GGATGG/ACGTGA`	2	--	us2k¹		9		NA WA	388
rs859539^1,2	C,F,H	--	38990946(-)	`CGTCCT/ACGGAC`	2	--	us2k¹		10		MN NS EA NA WA	840
rs113644955^1,2	C	--	38991222(+)	`TTCGGA/GCAAGT`	2	--	us2k¹		0	--	--	--	--
rs16879982^1,2	C,F,H	--	38991440(+)	`TGCACG/CGTCTC`	2	--	us2k¹		8		NA NS EA WA	680
rs28406422^1,2	C	--	38991489(+)	`TGTGTC/GTGTGT`	2	--	us2k¹		0	--	--	--	--
rs200075988^1,2	C	--	38991503(+)	`TGTGTG/TTGTGT`	2	--	us2k¹		0	--	--	--	--
rs201163543^1,2	C	--	38991512(+)	`GTGTGC/TGTGCG`	2	--	us2k¹		0	--	--	--	--
rs62443601^1,2		--	38991514(+)	`GTGTGC/TGCGCG`	2	--	us2k¹		1		NA	2
rs67413321^1,2	C	--	38991519(+)	`GTGTG-/GCGC CGCGC`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for POU6F2 (39017598 - 39267598 bp, first 250kb of POU6F2)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for POU6F2 (see all 21): About this table

Variant ID	Type	Subtype	PubMed ID
esv2734299	CNV	Deletion	23290073
esv2670994	CNV	Deletion	23128226
esv2734293	CNV	Deletion	23290073
esv2734297	CNV	Deletion	23290073
esv2734296	CNV	Deletion	23290073
esv2734294	CNV	Deletion	23290073
esv2236589	CNV	Deletion	18987734
esv1002601	CNV	Deletion	20482838
esv2670460	CNV	Deletion	23128226
esv1455501	CNV	Deletion	17803354

Human Gene Mutation Database (HGMD): POU6F2

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing POU6F2

DNA2.0 Custom Variant and Variant Library Synthesis for POU6F2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 609062
OMIM disorders: 601583
UniProtKB/Swiss-Prot: PO6F2_HUMAN, P78424

Hereditary susceptibility to Wilms tumor 5 (WT5) [MIM:601583]: Pediatric malignancy of kidney and one of

the most common solid cancers in childhood. Note=The disease is caused by mutations affecting the gene

represented in this entry

10 diseases for POU6F2:
About MalaCards

wilms tumor susceptibility-5 wilms tumor, type 1 wilms tumor 2 wilms tumor

nephroblastoma retinitis multiple myeloma myeloma

endotheliitis neuronitis

1 disease from the University of Copenhagen DISEASES database for POU6F2:

Nephroblastoma

POU6F2 for disorders About GeneDecksing

Genetic Association Database (GAD): POU6F2
Human Genome Epidemiology (HuGE) Navigator: POU6F2 (3 documents)

Export disorders for POU6F2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for POU6F2 gene, integrated from 10 sources (see all 15):
(articles sorted by number of sources associating them with POU6F2)

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Retina-derived POU-domain factor-1: a complex POU-domain gene implicated in the development of retinal ganglion and amacrine cells. (PubMed id 8601806)^{1, 2, 3, 9} Zhou H.... Nathans J. (J. Neurosci. 1996)
Human variation in alcohol response is influenced by variation in neuronal signaling genes. (PubMed id 20201926)^{1, 4} Joslyn G....White R.L. (Alcohol. Clin. Exp. Res. 2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (Mol. Med. 2010)
A genome-wide scan for common alleles affecting risk for autism. (PubMed id 20663923)^{1, 4} Anney R....Hallmayer J. (Hum. Mol. Genet. 2010)
Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14. (PubMed id 15459955)^{1, 4} Perotti D....Radice P. (Hum. Mutat. 2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (Nature 2003)
Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours. (PubMed id 11284034)^{1, 2} Perotti D.... Radice P. (Genes Chromosomes Cancer 2001)
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)¹ Lauc G....Rudan I. (PLoS Genet. 2013)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (amp 2008)
A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)⁴ Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11281	HGNC: 21694	AceView: POU6F2	Ensembl:ENSG00000106536	euGenes: HUgn11281
ECgene: POU6F2	H-InvDB: POU6F2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for POU6F2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for POU6F2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for POU6F2 gene
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Patent Information for POU6F2 gene:
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POU6F2 Gene

POU Class 6 Homeobox 2

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POU6F2 Gene

POU Class 6 Homeobox 2

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