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POU6F1 Gene

protein-coding   GIFtS: 56
GCID: GC12M051580

POU Class 6 Homeobox 1

(Previous names: POU domain, class 6, transcription factor 1)
  Search for POU6F1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
POU Class 6 Homeobox 11 2     MPOU Homeobox Protein2 3
POU Domain, Class 6, Transcription Factor 11 2     brain-52
Brain-Specific Homeobox/POU Domain Protein 52 3     brn-52
BRN52 3     Brain-53
MPOU2 3     Brn-53
TCFB12 3     

External Ids:    HGNC: 92241   Entrez Gene: 54632   Ensembl: ENSG000001842717   UniProtKB: Q148633   

Export aliases for POU6F1 gene to outside databases

Previous GC identifers: GC12U990075 GC12M051299 GC12M049869 GC12M048613


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for POU6F1 Gene:
POU6F1 (POU class 6 homeobox 1) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863
Function: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3') (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the POU6F1 gene promoter:
         E2F-4   E2F-3a   E2F-5   Nkx2-5   E2F-2   CREB   E2F   E2F-1   deltaCREB   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): POU6F1 promoter sequence
   Search Chromatin IP Primers for POU6F1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU6F1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

POU6F1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU6F1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M051580:  view genomic region     (about GC identifiers)

Start:
51,580,719 bp from pter      End:
51,611,477 bp from pter
Size:
30,759 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863 (See protein sequence)
Recommended Name: POU domain, class 6, transcription factor 1  
Size: 301 amino acids; 32645 Da
1 PDB 3D structure from and Proteopedia for POU6F1:
3D1N (3D)    
Secondary accessions: Q15944 Q6DK47 Q7Z7P6

Explore the universe of human proteins at neXtProt for POU6F1: NX_Q14863

Explore proteomics data for POU6F1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See POU6F1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002693.3  
    ENSEMBL proteins: 
     ENSP00000373895   ENSP00000330190   ENSP00000448389   ENSP00000448266  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    POU: Homeoboxes / POU class

    5 InterPro protein domains:
     IPR010982 Lambda_DNA-bd_dom
     IPR013847 POU
     IPR000327 POU_specific
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q14863

    ProtoNet protein and cluster: Q14863

    2 Blocks protein domains:
    IPB000327 POU domain
    IPB013847 POU


    UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863
    Similarity: Belongs to the POU transcription factor family. Class-6 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 POU-specific domain


    Find genes that share domains with POU6F1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PO6F1_HUMAN, Q14863
    Function: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3') (By
    similarity)

         Genatlas biochemistry entry for POU6F1:
    POU domain,class 6,transcription factor 1,mammalian homeo box backfoot,Drosophila bicoid related,expressed in
    Rathke pouch,at an early stage of pituitary development and in a subset of adult anterior pituitary cells that
    express POMC

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
         
    Find genes that share ontologies with POU6F1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for POU6F1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POU6F1
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    miRTarBase miRNAs that target POU6F1:
    hsa-mir-335-5p (MIRT018056)

    Block miRNA regulation of human, mouse, rat POU6F1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate POU6F1 (see all 63):
    hsa-miR-520e hsa-miR-302d hsa-miR-429 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-766 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmidPOU6F1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for POU6F1
    Predesigned siRNA for gene silencing in human, mouse, rat POU6F1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: POU6F1 (NM_002702)
    Sino Biological Human cDNA Clone for POU6F1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU6F1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU6F1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PO6F1_HUMAN, Q14863: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0031965nuclear membrane ----
    GO:0043231intracellular membrane-bounded organelle ----

    Find genes that share ontologies with POU6F1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for POU6F1 About    
    See pathways by source

    SuperPathContained pathways About
    1Transcription factors in neurogenesis
    Transcription factors in neurogenesis




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for POU6F1
    Interactions:

        Search GeneGlobe Interaction Network for POU6F1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for POU6F1 (Q148633 ENSP000003301904) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POU4F2Q128373, ENSP000002813214I2D: score=1 STRING: ENSP00000281321
    STAT3P407633, ENSP000002646574I2D: score=1 STRING: ENSP00000264657
    HOXD12P354523I2D: score=1 
    POU6F2P784243I2D: score=1 
    STAT2ENSP000003157684STRING: ENSP00000315768
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007420brain development TAS7908264
    GO:0007507heart development TAS7908264
    GO:0007517muscle organ development TAS7908264

    Find genes that share ontologies with POU6F1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for POU6F1 (PO6F1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for POU6F1 gene: 
    NM_002702.3  

    Unigene Cluster for POU6F1:

    POU class 6 homeobox 1
    Hs.555886  [show with all ESTs]
    Unigene Representative Sequence: NR_026893
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389243(uc001rxy.3 uc001rxz.3 uc001rya.3) ENST00000333640
    ENST00000550824 ENST00000552305 ENST00000547855 ENST00000549309 ENST00000546685
    ENST00000548692 ENST00000547854
    miRNA
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    Block miRNA regulation of human, mouse, rat POU6F1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate POU6F1 (see all 63):
    hsa-miR-520e hsa-miR-302d hsa-miR-429 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-766 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmidPOU6F1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for POU6F1
    Predesigned siRNA for gene silencing in human, mouse, rat POU6F1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU6F1
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat POU6F1
      QuantiFast Probe-based Assays in human, mouse, rat POU6F1

    Additional mRNA sequence: 

    AL832881.1 BC051326.1 BC074765.2 BC107090.1 L14482.1 NR_026893.1 Z21966.1 

    11 DOTS entries:

    DT.211139  DT.100019233  DT.92416809  DT.100719359  DT.121124774  DT.411233  DT.86852017  DT.100804567 
    DT.65284314  DT.95231668  DT.40200606 

    Selected AceView cDNA sequences (see all 36):

    AF268617 AA205845 CA503120 BV199669 BG569724 BV207798 Z21964 BV207801 
    AU123692 AA196616 BM857157 BQ278003 AA176079 CD048028 CD048171 BV174940 
    AW438879 AA232432 CD247215 CD049202 BM830060 CD247950 AA216545 CD248298 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for POU6F1 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b
    SP1:                                      -                 -                                             
    SP2:                                                        -                                             
    SP3:                                                                                                      
    SP4:        -                             -                                                               
    SP5:                    -                                                                                 


    ECgene alternative splicing isoforms for POU6F1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    POU6F1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGAAGGAA
    POU6F1 Expression
    About this image


    POU6F1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             ganglion/cranial/facial VII   
     
     Neural Tube (Nervous System)
             Primitive Spinal Cord
     
     Spinal Cord (Nervous System)
    POU6F1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    POU6F1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.555886

    UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863
    Tissue specificity: In the embryo, expressed exclusively in the developing brain, whereas in the adult its
    expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels
    are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum

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    QuantiFast Probe-based Assays in human, mouse, rat POU6F1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU6F1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for POU6F1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pou6f11 , 5 POU domain, class 6, transcription factor 11, 5 87.82(n)1
    95.35(a)1
      15 (56.35 cM)5
    190091  NM_010127.31  NP_034257.11 
     1005753185 
    lizard
    (Anolis carolinensis)
    Reptilia POU6F16
    POU class 6 homeobox 1
    47(a)
    1 ↔ 1
    2(67512138-67531505)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.130062 Transcribed sequence with strong similarity to protein more 80(n)    BX724095.1 
    zebrafish
    (Danio rerio)
    Actinopterygii pouc2 POU domain gene C 73.53(n)   30334  NM_131113.1 


    ENSEMBL Gene Tree for POU6F1 (if available)
    TreeFam Gene Tree for POU6F1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for POU6F1 gene
    POU5F22  POU6F22  POU4F22  POU2F32  POU3F12  POU3F42  POU1F12  POU3F32  
    POU4F32  POU3F22  POU2F22  POU5F1B2  POU4F12  POU2F12  POU5F12  
    Selected SIMAP similar genes for POU6F1 using alignment to 3 protein entries:     PO6F1_HUMAN (see all proteins) (see all similar genes):
    POU6F2    POU4F3    POU2F3    POU3F2    OCT6    POU3F1
    OCT-2    POU3F3    POU4F2    POU1F1    POU4F1    POU2F1
    POU5F1B    POU5F1P4    POU3F4    LHX9    EN2    GSC

    Find genes that share paralogs with POU6F1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for POU6F1 (see all 608)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1922152461,2
    --48626932(+) TGTAAA/GGACTG 1 -- us2k10--------
    rs107834181,2
    C,F,A,H--51580219(+) GCTCTT/CATCAG 2 -- ds500123Minor allele frequency- C:0.46NS EA NA WA CSA 2342
    rs1430268841,2
    C--51580225(+) ATCAGA/GCATCG 2 -- ds50010--------
    rs1913415261,2
    --51580308(+) AGGCAC/TTGAGT 2 -- ds50010--------
    rs1165358301,2
    C,F--51580459(+) CTAGGT/CATAAG 2 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1826330141,2
    --51580468(+) AGAAGC/GGTGTT 2 -- ds50010--------
    rs1481952601,2
    --51580618(+) TTTTCC/TAGGCT 2 -- ds50010--------
    rs111697521,2
    C,F,A,H--51580707(+) GGAAAC/AAAGCA 2 -- ds500119Minor allele frequency- A:0.15NS EA NA CSA WA 2344
    rs1411889981,2
    C--51580732(+) AAAAAA/TTACTG 2 -- ut31 nc-transcript-variant0--------
    rs769283551,2
    C,F--51580947(+) AACTCG/ATGTGT 2 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.05WA 118
    rs16071,2
    H--51580948(+) ACTCGT/CGTGTT 2 -- ut31 nc-transcript-variant5Minor allele frequency- C:0.00MN NS EA 604
    rs117381,2
    C,F,A,H--51581007(+) ATGCCA/GTGGTA 2 -- ut31 nc-transcript-variant24Minor allele frequency- N:0.00MN EA NA NS CSA 2708
    rs798095371,2
    C,F--51581098(+) ACACAG/ATTAAA 2 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.12EA 120
    rs1153538141,2
    C,F--51581184(+) CAAAAC/TAAAAT 2 -- ut31 nc-transcript-variant2Minor allele frequency- T:0.01WA NA 238
    rs1160376961,2
    C,F--51581201(+) CAACTC/TCTTCA 2 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.02WA 118
    rs111697531,2
    C,F,H--51581245(+) ACCTCC/TTAGGT 2 -- ut31 nc-transcript-variant5Minor allele frequency- T:0.16NS WA CSA 338
    rs783929741,2
    F--51581389(+) CTGCAA/CACCTC 2 -- ut31 nc-transcript-variant1Minor allele frequency- C:0.06WA 118
    rs1888916511,2
    C--51581396(+) CCTCCC/TACCCC 2 -- ut31 nc-transcript-variant0--------
    rs1469616091,2
    --51581546(+) CATGAC/TTGTTT 2 -- ut31 nc-transcript-variant0--------
    rs111697541,2
    C,F,A,H--51581565(+) TGACAC/TAGGAC 2 -- ut31 nc-transcript-variant11Minor allele frequency- T:0.15NS EA NA 848
    rs762138411,2
    C--51581713(+) TGCATC/TGCCAT 2 -- ut31 nc-transcript-variant0--------
    rs108761511,2
    C,F,A--51581740(+) GAGACC/AGAGTC 2 -- ut31 nc-transcript-variant8Minor allele frequency- A:0.28NA WA CSA 250
    rs1439710141,2
    --51581858(+) GATGTA/GCACTA 2 -- ut31 nc-transcript-variant0--------
    rs2004882471,2
    C--51581900(+) GAGAC-/GGGGTTT 2 -- ut31 nc-transcript-variant0--------
    rs1930997341,2
    --51581963(+) ACCTCA/GGCCTT 2 -- ut31 nc-transcript-variant0--------
    rs1506762621,2
    --51581977(+) AAGTGC/TTGGAA 2 -- ut31 nc-transcript-variant0--------
    rs1858695671,2
    --51581991(+) CAGGCA/GTAAGC 2 -- ut31 nc-transcript-variant0--------
    rs1389388831,2
    --51582000(+) GCCAAG/TGTGCC 2 -- ut31 nc-transcript-variant0--------
    rs1116658771,2
    C,F--51582048(+) TACAAG/ACTCTG 2 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.10NA 120
    rs1170613121,2
    C,F--51582086(+) GTTTGC/AAACAC 2 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.03EA 120
    rs107476051,2
    C,F,A,H--51582188(+) AAAGCC/TGGGTC 2 -- ut31 nc-transcript-variant16Minor allele frequency- T:0.35NS EA NA WA CSA 792
    rs1166072841,2
    F--51582189(+) AAGCTG/AGGTCA 2 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.01WA 118
    rs1888950291,2
    --51582263(+) CAGCAC/GAGCGT 2 -- ut31 nc-transcript-variant0--------
    rs1153674121,2
    --51582266(+) CAGAGC/TGTGTA 2 -- ut31 nc-transcript-variant0--------
    rs1426732591,2
    --51582272(+) GTGTA-/TGTGTGT 2 -- ut31 nc-transcript-variant0--------
    rs1138048491,2
    C,F--51582286(+) GTGTGC/TGCGCG 2 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.03WA 118
    rs1494432011,2
    --51582290(+) GCGCGC/TGTCTG 2 -- ut31 nc-transcript-variant0--------
    rs779627771,2
    C,F--51582300(+) GTGCGC/TGCTGC 2 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.04WA 118
    rs1446531851,2
    --51582311(+) ACGTGC/TGTGTG 2 -- ut31 nc-transcript-variant0--------
    rs598989681,2
    C,F--51582382(+) TGGCAC/TTGCAG 2 -- ut31 nc-transcript-variant3Minor allele frequency- T:0.08WA CSA 122
    rs1485103811,2
    --51582412(+) GTAAGC/TGGGAA 2 -- ut31 nc-transcript-variant0--------
    rs1442540191,2
    C--51582424(+) GGAAAC/GAGGAC 2 -- ut31 nc-transcript-variant0--------
    rs1922300111,2
    C--51582512(+) CTTCCC/TTCAGG 2 -- ut31 nc-transcript-variant0--------
    rs1460975571,2
    C--51582597(+) GGTGGC/TTGACC 2 -- ut31 nc-transcript-variant0--------
    rs1400913711,2
    --51582766(+) GCTAAC/TCCCCA 2 -- ut31 nc-transcript-variant0--------
    rs1440878151,2
    C--51582852(+) GGGATG/TGCTTA 2 -- ut31 nc-transcript-variant0--------
    rs1509965981,2
    --51582881(+) GACTCA/GACAAA 2 -- ut31 nc-transcript-variant0--------
    rs1408590291,2
    C--51583183(+) ACCCAA/CGTTTT 2 -- ut31 nc-transcript-variant0--------
    rs1838910281,2
    --51583239(+) AAGAAC/TAGCCT 2 -- ut31 nc-transcript-variant0--------
    rs1497487261,2
    C--51583363(+) TCCCCA/GCAAAG 2 -- ut31 nc-transcript-variant0--------
    rs733058011,2
    C,F--51583369(+) CAAAGG/CAACCA 2 -- ut31 nc-transcript-variant3Minor allele frequency- C:0.25WA 122
    rs1454437251,2
    C--51583416(+) CAGGGA/GTTTGG 2 -- ut31 nc-transcript-variant0--------
    rs11269051,2
    C,F--51583441(-) CCTTGA/GCCTCA 2 -- ut31 nc-transcript-variantese36Minor allele frequency- G:0.12NA 130
    rs34901,2
    C,F,A,H--51583506(-) AGGACC/TTGGGA 2 -- ut31 nc-transcript-variant26Minor allele frequency- N:0.00MN EA NA NS CSA WA 2754
    rs1886217551,2
    --51583514(+) CCTTTC/TGGTGC 2 -- ut31 nc-transcript-variant0--------
    rs123211051,2
    C,F,H--51583738(+) TCACCC/ATTCAG 2 -- ut31 nc-transcript-variantese311Minor allele frequency- A:0.08NS EA NA CSA WA 1312
    rs1411500551,2
    --51583776(+) AGTGAC/TGTCAC 2 -- ut31 nc-transcript-variant0--------
    rs1469384471,2
    C--51583795(+) TTCTTC/TGGAGT 2 -- ut31 nc-transcript-variant0--------
    rs1150510551,2
    C,F--51583883(+) GACATT/CGATGC 2 -- ut31 nc-transcript-variant1Minor allele frequency- C:0.01WA 118
    rs2015945931,2
    C--51583982(+) GGATGC/TCACGG 2 -- ut31 nc-transcript-variant0--------
    rs1379974421,2
    C--51584009(+) TAGAAC/GACAGG 2 -- ut31 nc-transcript-variant0--------
    rs1807481781,2
    C--51584048(+) AAGACA/GTTCAG 3 N syn10--------
    rs22282501,2
    C,F,H--51584147(-) CAGGAG/AATCAC 3 /E syn1 ese310Minor allele frequency- A:0.00MN NS EA NA 5398
    rs1860032521,2
    C--51584187(+) AGGCAC/TTGAGA 3 N S mis10--------
    rs1904526071,2
    C--51584296(+) CCGCAC/GTTCAG 3 L V mis10--------
    rs1395479281,2
    F--51584306(+) GCTTCG/ATTTAG 3 /N syn11Minor allele frequency- A:0.00NA 4552
    rs1821034691,2
    --51584578(+) TGCCCA/GGTCCT 2 -- int10--------
    rs124233521,2
    C,F,A,H--51584597(+) AACCAT/CTCCCA 2 -- int121Minor allele frequency- C:0.12NS EA NA WA 2760
    rs1433396301,2
    --51584604(+) CCCACA/GGCCTC 2 -- int10--------
    rs1483513781,2
    C--51584609(+) GGCCTC/G/TGGCTC 2 -- int10--------
    rs107182591,2
    C--51584693(+) AGTCC-/TTTTGA 2 -- int11Minor allele frequency- T:0.00CSA 4
    rs2010431141,2
    C--51584693(+) AGTCCC/TTNNNN 2 -- int10--------
    rs1415541431,2
    --51584880(+) CATCCC/TTGAGC 2 -- int10--------
    rs1509088521,2
    --51584890(+) CCATGC/TGCTTA 2 -- int10--------
    rs765682541,2
    C,F--51584891(+) CATGCG/ACTTAT 2 -- int11Minor allele frequency- A:0.03NA 120
    rs619328891,2
    C,F--51584913(+) ACTCTA/GTCCCT 2 -- int13Minor allele frequency- G:0.04NA EA 242
    rs74844301,2
    H--51584992(+) TGTTAG/AAGGGG 2 -- int1 trp34Minor allele frequency- A:0.00NS EA 414
    rs1381860111,2
    C--51585043(+) GCCAAC/TATAGA 2 -- int10--------
    rs116083641,2
    C,F,H--51585055(+) TGGAAG/ATTCCC 2 -- int126Minor allele frequency- A:0.18NS EA NA WA 3124
    rs1165730231,2
    C,F--51585062(+) TCCCAC/TTTTGG 2 -- int11Minor allele frequency- T:0.03WA 118
    rs3725715231,2
    C--51585162(+) CCCAGA/C/GTTGGA 2 -- int10--------
    rs1407213581,2
    C--51585179(+) ATCTT-/CCAGAG 2 -- int10--------
    rs108761521,2
    C,F,A,H--51585191(+) CCTCAG/CAAGGA 2 -- int113Minor allele frequency- C:0.18NS EA NA 1028
    rs74871571,2
    C,F,A,H--51585304(+) GGTGCT/CCAGGT 2 -- int120Minor allele frequency- C:0.38NA NS EA WA CSA 916
    rs107834191,2
    C,F,A,H--51585335(+) ACCAGG/ACAGCT 2 -- int129Minor allele frequency- A:0.35NS EA NA WA CSA EU 3325
    rs1475638551,2
    --51585398(+) TGGCT-/GGTAGG 3 S QP fra10--------
    rs1506003151,2
    C,F--51585471(+) CGCCGG/TATCTT 3 I syn12Minor allele frequency- T:0.00NA EU 5733
    rs1396267861,2
    F--51585526(+) CCTCAT/CCCAGA 3 /D /G mis11Minor allele frequency- C:0.00NA 4548
    rs107358311,2
    C,F,A,H--51585599(+) ATCCCT/GGCTTA 2 -- int112Minor allele frequency- G:0.25NS EA NA WA CSA 638
    rs107476061,2
    C,F,A,H--51585601(+) CCCTGC/TTTATC 2 -- int18Minor allele frequency- T:0.35NA WA EA 372
    rs1427388091,2
    --51585628(+) ACTGAC/TGCAGT 2 -- int10--------
    rs1171459811,2
    C,F--51585629(+) CTGACG/ACAGTA 2 -- int11Minor allele frequency- A:0.03NA 120
    rs1865691271,2
    --51585634(+) GCAGTA/GGTGAG 2 -- int10--------
    rs1176233371,2
    F--51585638(+) TAGTGA/CGAGGT 2 -- int11Minor allele frequency- C:0.01NA 120
    rs1460707251,2
    --51585740(+) TCTCCA/GGGGGT 2 -- int10--------
    rs107476071,2
    C,F,A,H--51585869(+) ATAGCG/AGAGAC 2 -- int124Minor allele frequency- A:0.36NS EA NA WA CSA 2352
    rs112768171,2
    C--51585884(+) CATGG-/CTC   
       GGCCT
    CTCCA
    2 -- int10--------
    rs1905756241,2
    --51585979(+) AAAAGC/GCAGCC 2 -- int10--------
    rs1831364691,2
    --51586040(+) AAGCAC/GCATCT 2 -- int10--------
    rs71369041,2
    C,F--51586138(+) GTGGGG/AGTCTC 3 /T syn1 ese32Minor allele frequency- A:0.00NS NA 4630
    rs1396294851,2
    C--51586185(+) CTTGGC/TGGCTG 3 T A mis11Minor allele frequency- T:0.00NA 4552
    rs1451664301,2
    F--51586186(+) TTGGCG/AGCTGG 3 /A syn11Minor allele frequency- A:0.00NA 4552
    rs1400767001,2
    C--51586419(+) ATGGTA/GGCTGA 2 -- int10--------
    rs1420454771,2
    --51586458(+) CAAGGC/TGGGAG 2 -- int10--------
    rs96686431,2
    C,F--51586490(+) TGATAT/CCAGCC 2 -- int15Minor allele frequency- C:0.17NA WA EA 362
    rs1912206441,2
    C--51586520(+) CTGTCC/TCTACT 2 -- int10--------
    rs1439993121,2
    --51586524(+) CTCTAC/TTAAAA 2 -- int10--------
    rs1826121301,2
    C--51586545(+) TAGCTA/GGGCAT 2 -- int10--------
    rs1486691551,2
    C--51586557(+) GTGGTA/GGGTGC 2 -- int10--------
    rs579370701,2
    C--51586604(+) AATTGC/TTTGAA 2 -- int10--------
    rs1875824961,2
    --51586642(+) AAGATC/TGCGCC 2 -- int10--------
    rs1512163531,2
    C--51586649(+) CGCCAC/TTGCAC 2 -- int10--------
    rs1927920991,2
    C--51586682(+) GACTCC/TGTCTC 2 -- int10--------
    rs1398038271,2
    --51586683(+) ACTCCA/GTCTCA 2 -- int10--------
    rs1838020851,2
    --51586997(+) ATCTCC/TCTACC 2 -- int10--------
    rs1450183721,2
    --51587097(+) CGGGCA/GCGGTG 2 -- int10--------
    rs1878550781,2
    --51587108(+) GCTCAC/TGCACT 2 -- int10--------
    rs1919601491,2
    --51587127(+) CCAAAA/GGGGGC 2 -- int10--------
    rs1475744261,2
    C--51587281(+) TTGAAC/TACGGG 2 -- int10--------
    rs575159451,2
    C,F--51587283(+) GAACAC/TGGGAG 2 -- int11Minor allele frequency- T:0.50WA 2
    rs65808051,2
    C,H--51587295(+) CAGAGG/ATTGCA 2 -- int110Minor allele frequency- A:0.22NA WA CSA 143
    rs1501166091,2
    C--51587303(+) GCAGTA/GAGCCG 2 -- int10--------
    rs1843987421,2
    --51587307(+) TAAGCC/TGAGAG 2 -- int10--------
    rs1148449691,2
    C,F--51587380(+) AATTTA/TAAAAA 2 -- int11Minor allele frequency- T:0.04WA 118
    rs1457954131,2
    --51587394(+) GAAAAC/TCAGTT 2 -- int10--------
    rs1883995771,2
    --51587428(+) AATACA/GTATGA 2 -- int10--------
    rs1927180281,2
    --51587522(+) CTTTTC/TACATT 2 -- int10--------
    rs1850799141,2
    --51587589(+) ACTATA/GAATAT 2 -- int10--------
    rs111697561,2
    A--51587868(+) GCAGTA/GGCATG 2 -- int10--------
    rs111697571,2
    C,A--51587872(+) TAGCAC/TGATCT 2 -- int15Minor allele frequency- T:0.10NA WA CSA 10
    rs1437776121,2
    --51587878(+) GATCTC/GGGCTC 2 -- int10--------
    rs1891389981,2
    --51588098(+) AGCCAC/TTGTGC 2 -- int10--------
    rs128198541,2
    C,F--51588167(+) gcctgG/Taatac 2 -- int16Minor allele frequency- T:0.33NA WA CSA 12
    rs1431002431,2
    C--51588290(+) GTGGTA/GGTGCA 2 -- int10--------
    rs589598031,2
    --51588315(+) GCTACC/TGGGGA 2 -- int10--------
    rs128187181,2
    C,F,A--51588372(+) gagccA/Gaggtc 2 -- int111Minor allele frequency- G:0.45NA WA CSA EA 257
    rs1810340371,2
    --51588378(+) AGGTCA/GCATCA 2 -- int10--------
    rs1863690471,2
    --51588418(+) ACCCTC/GGTCTC 2 -- int10--------
    rs111697581,2
    C,F,A--51588441(+) AAAAAG/AGCTCA 2 -- int1 trp35Minor allele frequency- A:0.25WA NA 12
    rs593341701,2
    C--51588441(+) AAAAA-/AG/G  
            
    GCTCA
    2 -- int10--------
    rs1388186211,2
    --51588494(+) GTTCCC/TTACTA 2 -- int10--------
    rs108761531,2
    C,F,A,H--51588509(+) ACCTGT/ATAATG 2 -- int116Minor allele frequency- A:0.46NS EA NA WA CSA 795
    rs733077051,2
    C,F--51588554(+) CTTTCT/CGTGCG 2 -- int12Minor allele frequency- C:0.19WA 120
    rs1114150941,2
    C--51588616(+) GAAGTT/CGGTAC 2 -- int13Minor allele frequency- C:0.04CSA WA NA 240
    rs124228461,2
    C,F,H--51588677(+) GGAAGT/CGCATG 2 -- int14Minor allele frequency- C:0.11NA WA EA 362
    rs1414517301,2
    C--51588739(+) AACTCC/TTGGAC 2 -- int10--------
    rs72973981,2
    C,F--51588844(+) agaacT/CgctgC 2 -- int12Minor allele frequency- C:0.16CSA WA 120
    rs1508577491,2
    --51588939(+) TCTTGC/TTATGT 2 -- int10--------
    rs1393214641,2
    C--51588997(+) ACTGCA/GGCCTT 2 -- int10--------
    rs1492936321,2
    --51589009(+) AACTCC/TTGGCC 2 -- int10--------
    rs124270031,2
    C,H--51589020(+) TCAAGC/TGATCC 2 -- int14Minor allele frequency- T:0.07NA WA EA 362
    rs1474159601,2
    --51589035(+) CCTTAA/GCCTCC 2 -- int10--------
    rs675314341,2
    C--51589294(+) GGAAT-/AATAGT 2 -- int12Minor allele frequency- A:0.25NA CSA 4
    rs1814664311,2
    --51589338(+) GAGTAA/TATCAA 2 -- int10--------
    rs1861045461,2
    --51589349(+) AGCCAC/TGGTGC 2 -- int10--------
    rs1397657291,2
    --51589403(+) CAGAAA/CTGACT 2 -- int10--------
    rs1452980631,2
    --51589468(+) ACTTTA/GACCAT 2 -- int10--------
    rs1920687211,2
    --51589552(+) GTAGGA/GGGTCT 2 -- int10--------
    rs1475513651,2
    C--51589559(+) GTCTCA/GTGGTG 2 -- int10--------
    rs578210221,2
    C,F--51589663(+) TCAGAA/CGATGC 2 -- int12Minor allele frequency- C:0.09NA EA 240
    rs1158163771,2
    C,F--51589679(+) TGCCTG/AGCAGT 2 -- int11Minor allele frequency- A:0.01WA 118
    rs1997225151,2
    --51589736(+) CCACCA/CCCCCC 2 -- int10--------
    rs2013991481,2
    C--51589791(+) CTTCCA/G/TGACAG 5 R W syn1 mis10--------
    rs1475826371,2
    C--51589851(+) CTGGGC/TGTTCA 3 T A mis11Minor allele frequency- T:0.00NA 4284
    rs1812386661,2
    C--51589915(+) GCCGCA/CACACT 3 V syn10--------
    rs1132852961,2
    F--51589996(+) GGGTAG/TCATCC 2 -- int12Minor allele frequency- T:0.50CSA 4
    rs749613151,2
    C,F--51590188(+) AGAGAC/TCTGCC 2 -- int11Minor allele frequency- T:0.23EA 120
    rs592457651,2
    C,F--51590278(+) CTCCAT/ACTAAT 2 -- int13Minor allele frequency- A:0.06CSA WA 121
    rs1403127581,2
    --51590299(+) TCCAAA/CGAAAG 2 -- int10--------
    rs1867009471,2
    --51590369(+) AAATGA/TAAACT 2 -- int10--------
    rs1420992161,2
    C--51590479(+) CTTGAC/TGTCTG 2 -- int10--------
    rs3693550751,2
    C--51590527(+) CCATCC/TCCTGG 2 -- int10--------
    rs779056001,2
    C,F--51590593(+) CTGAGC/TATTGG 3 T A mis11Minor allele frequency- T:0.06EA 120
    rs1906879281,2
    C--51590606(+) AGGATA/CTGACT 3 Q H mis10--------
    rs1511630721,2
    C--51590638(+) AATGGC/TGCTGG 2 -- ut51 nc-transcript-variant1Minor allele frequency- T:0.00EU 1323
    rs1822644581,2
    --51590723(+) TGGAGA/GAAGAG 2 -- int10--------
    rs73985481,2
    C,F--51590898(+) CTACCG/TGCTGG 2 -- int15Minor allele frequency- T:0.00NA 10
    rs1504531201,2
    --51591084(+) GCCACA/GGTCAT 2 -- int10--------
    rs1875861261,2
    --51591147(+) CCACAA/CTGGAG 2 -- int10--------
    rs774886521,2
    C,F--51591183(+) TAACGC/GCTCCC 2 -- int12Minor allele frequency- G:0.05CSA WA 120
    rs777250301,2
    F--51591200(+) AAGCCA/GGGAGC 2 -- int11Minor allele frequency- G:0.03WA 118
    rs1909355461,2
    --51591231(+) ATAGAA/GCTGTA 2 -- int10--------
    rs1466085151,2
    --51591286(+) CAGACA/GTCATC 2 -- int10--------
    rs1413881171,2
    --51591301(+) CCTCCA/CAGCCT 2 -- int10--------
    rs2011080821,2
    C--51591454(+) GTTTT-/GGGGGG 2 -- int10--------
    rs1827319871,2
    --51591456(+) TTTCGC/GGGGGG 2 -- int10--------
    rs1451722461,2
    --51591509(+) CATGAC/TTCCGT 2 -- int10--------
    rs1387997841,2
    C--51591512(+) GATTCC/TGTCCA 2 -- int10--------
    rs1883720841,2
    C--51591967(+) CGCACA/GCCAGC 2 -- us2k1 int10--------
    rs733077061,2
    --51592257(+) AGTCCA/GACATG 2 -- us2k1 int10--------
    rs1121920431,2
    C--51592332(+) CGTTAG/CCTTGG 2 -- us2k1 spd11Minor allele frequency- C:0.00CSA 1
    rs1493448081,2
    --51592368(+) CTCCCC/TCCGTA 2 -- us2k1 nc-transcript-variant0--------
    rs1436753791,2
    C--51592385(+) GCAGCA/GGTCAG 2 -- us2k1 nc-transcript-variant0--------
    rs40768841,2
    C,F--51592761(+) TCCTGC/ACTTCA 2 -- us2k1 int12Minor allele frequency- A:0.12NA EA 240
    rs733077071,2
    C,F--51592804(+) CTGCTC/TACAGG 2 -- us2k1 int13Minor allele frequency- T:0.05WA 122
    rs802217261,2
    C--51592936(+) AAGTGC/GTCAAG 2 -- us2k1 int10--------
    rs111697591,2
    C--51592956(+) AGGCTA/GATGGA 2 -- us2k1 int10--------
    rs1489540081,2
    C--51592970(+) AAGTGC/GTCAAG 2 -- us2k1 int10--------
    rs73980101,2
    C,A--51592981(+) GCCCCA/GCAGAG 2 -- us2k1 int10--------
    rs1473921111,2
    C--51593049(+) CCATAC/TCCTTG 2 -- us2k1 int10--------
    rs351254081,2
    C,F--51593212(+) TGGAGG/AGCCGG 2 -- us2k1 int12Minor allele frequency- A:0.10NA EA 240
    rs1931971221,2
    --51593216(+) GGGCCA/GGCAAG 2 -- us2k1 int10--------
    rs1846888881,2
    --51593232(+) TCATTA/CATTTA 2 -- us2k1 int10--------
    rs342968491,2
    C,F--51593267(+) GCTGCG/ATGAAA 2 -- us2k1 int15Minor allele frequency- A:0.23CSA WA NA EA 362
    rs785635131,2
    C,F--51593312(+) AAGGAG/AATGAT 2 -- us2k1 int11Minor allele frequency- A:0.30WA 118
    rs40770931,2
    C,F,A,H--51593616(-) CTGCCA/C/G/
            
    CTGCC
    4 -- us2k1 nc-transcript-variant21NS EA NA WA CSA EU 1466
    rs1883780031,2
    --51593866(+) GGGGAG/TCCCTG 2 -- us2k1 int10--------
    rs1165520021,2
    C,F--51593945(+) CCCTCA/GTTTCC 2 -- us2k1 int12Minor allele frequency- G:0.13WA EA 238
    rs1381231891,2
    --51594287(+) TTTCCC/TGTGAC 1 -- int10--------
    rs798866141,2
    C,F--51594288(+) TTCCCG/ATGACC 1 -- int11Minor allele frequency- A:0.31WA 118
    rs1838286461,2
    --51594513(+) TCACCC/TATGCT 1 -- int10--------
    rs1174278331,2
    C,F--51594714(+) CAAGTG/AATGTG 1 -- int12Minor allele frequency- A:0.16NA EA 240
    rs1163365111,2
    C,F--51594768(+) ACCGCG/ACCTGG 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1472246281,2
    --51594941(+) ATAACC/TGCAAA 1 -- int10--------
    rs752314931,2
    C,F--51594948(+) CAAAGG/TTTCTG 1 -- int11Minor allele frequency- T:0.29WA 118
    rs1396427771,2
    --51595050(+) CCAGGC/TAGTTT 1 -- int10--------
    rs733077091,2
    C--51595068(+) TCAAGG/AGACAA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1892808981,2
    --51595089(+) ACAAAA/GGCCTT 1 -- int10--------
    rs106351771,2
    C--51595317(+) gagTT-/AAAAAAA 1 -- int1 tfbs3 trp30--------
    rs1447488841,2
    --51595318(+) GAGTT-/AAAAAA 1 -- int10--------
    rs731069741,2
    C--51595327(+) AAAAAA/CCAAAA 1 -- int10--------
    rs113848981,2
    C--51595328(+) AAAAC-/A/A   
       A
    /AAC
    AAAAA
    1 -- int10--------
    rs1496618601,2
    --51595432(+) ATGGGA/CAAGTG 1 -- int10--------
    rs111697611,2
    C,F,A,H--51595505(+) ATTTAG/ATAGGA 1 -- int130Minor allele frequency- A:0.47NS EA NA WA 3184
    rs1170974871,2
    C,F--51595546(+) GGCTGC/TTATTG 1 -- int11Minor allele frequency- T:0.01NA 120
    rs719147741,2
    C--51595639(+) TATAG-/TTGTT 
            
    TTTTT
    1 -- int10--------
    rs111697621,2
    C,A--51595641(+) TAGTTG/TTTTTT 1 -- int11Minor allele frequency- T:0.50WA 2
    rs2021457551,2
    --51595643(+) TTGTT-/GTTTTT 1 -- int10--------
    rs679636981,2
    C--51595645(+) TAGTT-/GTTTT 
            
    TTTTT
    1 -- int11Minor allele frequency- GTTTT:0.00NA 2
    rs1444626071,2
    --51595711(+) AATCTC/TGCCTC 1 -- int10--------
    rs79757371,2
    C,A--51595737(+) tcccaA/Ggctca 1 -- int16Minor allele frequency- G:0.36NA WA EA 246
    rs1484279521,2
    C--51595855(+) CCCAGA/GCTGGT 1 -- int10--------
    rs79762921,2
    C,A--51595928(+) cgtgaA/Gccacc 1 -- int17Minor allele frequency- G:0.33NA WA 132
    rs1440480261,2
    --51595960(+) TTTTAC/TCATTG 1 -- int10--------
    rs1465974281,2
    C--51596020(+) CTTTTC/TTTCTC 1 -- int10--------
    rs123072091,2
    --51596240(+) gtagcC/Tgggat 1 -- int10--------
    rs1413626031,2
    --51596302(+) AAAGAC/TGGGGT 1 -- int10--------
    rs1995337511,2
    --51596665(+) ATAGT-/AAATTT 1 -- int10--------
    rs107358321,2
    C,F,A,H--51596763(+) AATACT/CGCACA 1 -- int124Minor allele frequency- C:0.50NS EA NA WA CSA 2348
    rs763185551,2
    F--51596873(+) GGAGGC/TGTTTG 1 -- int12Minor allele frequency- T:0.09CSA WA 120
    rs1850711441,2
    --51596977(+) ATTTGA/GATAAG 1 -- int10--------
    rs1438315341,2
    --51597056(+) GCATGA/TTGAAT 1 -- int10--------
    rs1501177801,2
    C--51597080(+) CTCCC-/CTGTTTT 1 -- int10--------
    rs1899174291,2
    --51597193(+) TGGGAA/GCAGGT 1 -- int10--------
    rs73975861,2
    C,F--51597384(+) GTTAAG/TGAGCT 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1820813911,2
    --51597388(+) AGGAGA/CTGTTG 1 -- int10--------
    rs1406450751,2
    C--51597400(+) TTTTCA/GGAAGT 1 -- int10--------
    rs1504021361,2
    --51597459(+) CCCACA/CAGTCC 1 -- int10--------
    rs1400728431,2
    C--51597569(+) GCAGA-/AGGAGATG 1 -- int10--------
    rs1381498841,2
    --51597615(+) TGAGAA/GGGTGC 1 -- int10--------
    rs1862287741,2
    --51597790(+) GAGTGG/TAGAGT 1 -- int10--------
    rs602861201,2
    C,F--51597879(+) ATTCAT/CGCTGG 1 -- int14Minor allele frequency- C:0.09WA CSA 124
    rs123008681,2
    --51597899(+) GACCAC/TAGGAG 1 -- int10--------
    rs20679021,2
    C,F,A,H--51597909(-) TGCCAG/AGTCCC 1 -- int112Minor allele frequency- A:0.45NA WA CSA EA 376
    rs1465795861,2
    C--51597913(+) CTTGGC/TACTCA 1 -- int10--------
    rs1914719781,2
    --51597926(+) TGGAGC/TAGTAC 1 -- int10--------
    rs1807097761,2
    C--51597973(+) CAGAGA/GAGCCC 1 -- nc-transcript-variant0--------
    rs1851025081,2
    --51598146(+) ATCACA/GATGAC 1 -- nc-transcript-variant0--------
    rs1899059231,2
    --51598205(+) GCAGGA/GTCCAA 1 -- int10--------
    rs1832116841,2
    --51598431(+) GAGCTA/CATTTC 1 -- int10--------
    rs72981951,2
    C--51598612(+) GAAACC/GATCTG 1 -- int10--------
    rs1168939601,2
    F--51598638(+) TAAAGG/TGATGG 1 -- int11Minor allele frequency- T:0.01EA 120
    rs116137521,2
    H--51598658(+) GCTCCA/CCAATG 1 -- int10--------
    rs1152330851,2
    F--51598685(+) GCCCAT/CGATTC 1 -- int11Minor allele frequency- C:0.01WA 118
    rs572842381,2
    C--51598853(+) GTCTCA/GCTCTG 1 -- int10--------
    rs1891969751,2
    --51599058(+) GATCTC/TGTGAT 1 -- int10--------
    rs125793471,2
    C,H--51599231(+) GGACCC/TTGAGC 1 -- int15Minor allele frequency- T:0.00NS EA NA 420
    rs113303731,2
    C--51599250(+) AACAC-/TTAAGT 1 -- int10--------
    rs611415481,2
    C--51599251(+) ACACT-/A/TAAGTC 1 -- int11NA 2
    rs113384271,2
    C,F--51599252(+) CACTTA/-AGTCT 1 -- int13Minor allele frequency- -:0.33NA CSA 6
    rs560507941,2
    C--51599252(+) CACTTC/AAGTCT 1 -- int13Minor allele frequency- A:0.20NA CSA 5
    rs65808061,2
    C,F,A,H--51599339(+) TCAGAG/AACAAA 1 -- int124Minor allele frequency- A:0.14NS EA NA WA CSA 2355
    rs1914971401,2
    --51599380(+) CTCTGC/TGCATT 1 -- int10--------
    rs1837603131,2
    --51599446(+) CAGTCA/GGAGGC 1 -- int10--------
    rs1878496721,2
    C--51599497(+) TGAGAC/TGAGTG 1 -- int10--------
    rs1482697751,2
    --51599672(+) ATCTCA/GGCTCA 1 -- int10--------
    rs1444739931,2
    C--51599747(+) ACAGGA/TGCCCA 1 -- int10--------
    rs65808071,2
    C--51599792(+) gagacG/Agggtt 1 -- int14Minor allele frequency- A:0.00NA WA 8
    rs1917911901,2
    --51599934(+) CGGGCA/GCGGTG 1 -- int10--------
    rs1843359811,2
    --51600064(+) TAGCCA/GGGTGT 1 -- int10--------
    rs1489615881,2
    C--51600067(+) CCGGGC/TGTGGT 1 -- int10--------
    rs1997697861,2
    C--51600260(+) TTTGC-/AAAAAAAA 1 -- int10--------
    rs1167388621,2
    C,F--51600473(+) CCCTGG/TTAAGA 1 -- int11Minor allele frequency- T:0.11WA 118
    rs1512803631,2
    C--51600545(+) CCTTA-/CCCCCC 1 -- int10--------
    rs1915590591,2
    --51600721(+) ACAATA/TTCTAT 1 -- int10--------
    rs1440285811,2
    C--51600805(+) AAAAAA/CAAAAA 1 -- int10--------
    rs1848177911,2
    --51600933(+) CACTCA/GAGTAG 1 -- int10--------
    rs1907167871,2
    --51600964(+) CACCAC/TGCCAG 1 -- int10--------
    rs1815116741,2
    --51600973(+) AGGCTA/GATTTT 1 -- int10--------
    rs1459637741,2
    --51601242(+) CAGTCC/TGGTGG 1 -- int10--------
    rs748202071,2
    C,F--51601402(+) GATCAT/CCACCT 1 -- int12Minor allele frequency- C:0.16NA EA 240
    rs73988981,2
    C,A,H--51601489(+) ATAAAG/ATACAG 1 -- int111Minor allele frequency- A:0.17NA WA CSA EA 377
    rs1398838791,2
    C--51601594(+) GAATCA/GGCTCT 1 -- int10--------
    rs1437889301,2
    --51601650(+) CAGAGA/GAGGTG 1 -- int10--------
    rs1458389521,2
    C--51601756(+) CAGTCA/GTAAGA 1 -- int10--------
    rs114357151,2
    C--51601894(+) AAAAA-/A/CTTAGC 1 -- int11NA 2
    rs1148217451,2
    F--51602004(+) AGATCG/ACTTGA 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1489953211,2
    --51602012(+) TGAGCC/TTGGGA 1 -- int10--------
    rs756027561,2
    C,F--51602013(+) GAGCCT/CGGGAG 1 -- int12Minor allele frequency- C:0.15NA EA 240
    rs79789561,2
    C,A,H--51602021(+) gaggcG/Agaggt 1 -- int110Minor allele frequency- A:0.17NA WA CSA EA 255
    rs585602011,2
    C,F--51602078(+) GACCCT/GGTCTC 1 -- int14Minor allele frequency- G:0.14WA CSA EA 242
    rs1853126631,2
    --51602183(+) TTGTAC/TGCTAG 1 -- int10--------
    rs1429791521,2
    --51602241(+) GGGGGC/TGTGGG 1 -- int10--------
    rs801705851,2
    --51602268(+) TATCCC/GCATGT 1 -- int10--------
    rs750731501,2
    C,F--51602354(+) TCCCCG/CCAAAT 1 -- int13Minor allele frequency- C:0.13WA NA EA 358
    rs1409474501,2
    C--51602391(+) GGTGGA/GTAGTA 1 -- int10--------
    rs795829691,2
    C,F--51602411(+) AGGGCC/TTCTGG 1 -- int12Minor allele frequency- T:0.18NA EA 240
    rs1464221131,2
    C--51602445(+) TGCCCA/GTATAA 1 -- int10--------
    rs1391220231,2
    --51602787(+) AAGTGA/GGTCCT 1 -- int10--------
    rs761522441,2
    F--51602802(+) AGACAA/CCACCA 1 -- int11Minor allele frequency- C:0.09WA 118
    rs65808081,2
    C,F,A,H--51602852(+) taaatC/Ttctgt 1 -- int113Minor allele frequency- T:0.38NS NA WA EA 610
    rs111697651,2
    C,F--51602879(+) AGTTTA/GTGGTA 1 -- int11Minor allele frequency- G:0.06EA 120
    rs116145751,2
    H--51602883(+) tatggG/Tatttt 1 -- int10--------
    rs1416862051,2
    C--51602913(+) ACTACA/GATAAA 1 -- int10--------
    rs1459432821,2
    C--51603066(+) TAACAA/GTCATT 1 -- int10--------
    rs1163375241,2
    F--51603190(+) GTCTAG/ACTTCT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1893943251,2
    --51603301(+) ATTTTA/GTTTAT 1 -- int10--------
    rs1172347131,2
    F--51603376(+) GACTAT/CTGGGT 1 -- int11Minor allele frequency- C:0.02EA 120
    rs111697661,2
    C,F,H--51603753(+) tttttT/Ctgttt 1 -- int15Minor allele frequency- C:0.03NS EA NA 530
    rs104314871,2
    C,A,H--51603791(+) GGCTGT/GAATGC 1 -- int19Minor allele frequency- G:0.45NA WA EA 370
    rs1811997821,2
    --51603812(+) CCATGA/GCTCAT 1 -- int10--------
    rs1856391361,2
    --51604054(+) GGGATA/GAGCTA 1 -- int10--------
    rs1385881811,2
    --51604081(+) TAGAAA/GCCATT 1 -- int10--------
    rs1881015901,2
    --51604086(+) GCCATG/TTGCAA 1 -- int1