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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POU6F1 Gene

protein-coding   GIFtS: 55
GCID: GC12M051580

POU Class 6 Homeobox 1

(Previous names: POU domain, class 6, transcription factor 1)
  2 related diseases
at
MalaCards
 

Aliases
for POU6F1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
POU Class 6 Homeobox 11 2     MPOU Homeobox Protein2 3
POU Domain, Class 6, Transcription Factor 11 2     brain-52
Brain-Specific Homeobox/POU Domain Protein 52 3     brn-52
BRN52 3     Brain-53
MPOU2 3     Brn-53
TCFB12 3     

External Ids:    HGNC: 92241   Entrez Gene: 54632   Ensembl: ENSG000001842717   UniProtKB: Q148633   
ORGUL members:         
NONCODE14:n407436      

Export aliases for POU6F1 gene to outside databases

Previous GC identifers: GC12U990075 GC12M051299 GC12M049869 GC12M048613


Summaries
for POU6F1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
GeneCards Summary for POU6F1 Gene: 
POU6F1 (POU class 6 homeobox 1) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with POU6F1 include clear cell adenocarcinoma, and adenocarcinoma. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863
Function: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3') (By
similarity)




Genomic Views
for POU6F1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POU6F1 gene promoter:
         E2F-4   E2F-3a   E2F-5   Nkx2-5   E2F-2   CREB   E2F   E2F-1   deltaCREB   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): POU6F1 promoter sequence
   Search SABiosciences Chromatin IP Primers for POU6F1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU6F1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.13

POU6F1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU6F1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M051580:  view genomic region     (about GC identifiers)

Start:
 51,580,719 bp from pter      End:
 51,611,477 bp from pter
Size:
 30,759 bases      Orientation:
 minus strand

Proteins
for POU6F1 gene

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section
UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863 (See protein sequence)
Recommended Name: POU domain, class 6, transcription factor 1  
Size: 301 amino acids; 32645 Da
Subcellular location: Nucleus
1 PDB 3D structure from and Proteopedia for POU6F1:
3D1N (3D)    
Secondary accessions: Q15944 Q6DK47 Q7Z7P6

Explore the universe of human proteins at neXtProt for POU6F1: NX_Q14863

Explore proteomics data for POU6F1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q14863

    • POU6F1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    POU6F1 Protein Expression
    REFSEQ proteins: NP_002693.3  
    ENSEMBL proteins: 
     ENSP00000373895   ENSP00000330190   ENSP00000448389   ENSP00000448266  

    Human Recombinant Protein Products for POU6F1: 
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    Novus Biologicals POU6F1 Proteins
    Novus Biologicals POU6F1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for POU6F1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0031965nuclear membrane IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    POU6F1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for POU6F1 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    		 HGNC Gene Families: 
    POU: Homeoboxes / POU class

    5 InterPro protein domains:
     IPR010982 Lambda_DNA-bd_dom
     IPR013847 POU
     IPR000327 POU_specific
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q14863

    ProtoNet protein and cluster: Q14863

    2 Blocks protein domains:
    IPB000327 POU domain
    IPB013847 POU


    UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863
    Similarity: Belongs to the POU transcription factor family. Class-6 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 POU-specific domain


    POU6F1 for domains           About GeneDecksing


    Function
    for POU6F1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PO6F1_HUMAN, Q14863
    Function: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3') (By
    similarity)

         Genatlas biochemistry entry for POU6F1:
    POU domain,class 6,transcription factor 1,mammalian homeo box backfoot,Drosophila bicoid related,expressed in Rathke
    pouch,at an early stage of pituitary development and in a subset of adult anterior pituitary cells that express POMC

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
         
    POU6F1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for POU6F1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for POU6F1 
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    miRNA
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    hsa-miR-520e hsa-miR-302d hsa-miR-429 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-766 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmid: POU6F1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Pathways & Interactions
    for POU6F1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for POU6F1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transcription factors in neurogenesis
    		Transcription factors in neurogenesis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for POU6F1
        Transcription factors in neurogenesis





    POU6F1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POU6F1

    4 Interacting proteins for POU6F1 (Q148633) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HOXD12P354523I2D: score=1 
    POU4F2Q128373I2D: score=1 
    POU6F2P784243I2D: score=1 
    STAT3P407633I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0007420brain development TAS7908264
    GO:0007507heart development TAS7908264
    GO:0007517muscle organ development TAS7908264

    POU6F1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for POU6F1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for POU6F1 (PO6F1)

    Search CenterWatch for drugs/clinical trials and news about POU6F1 / PO6F1

    Transcripts
    for POU6F1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for POU6F1 gene: 
    NM_002702.3  

    Unigene Cluster for POU6F1:

    POU class 6 homeobox 1
    Hs.555886  [show with all ESTs]
    Unigene Representative Sequence: NR_026893
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389243(uc001rxy.3 uc001rxz.3 uc001rya.3) ENST00000333640
    ENST00000550824 ENST00000552305 ENST00000547855 ENST00000549309 ENST00000546685
    ENST00000548692 ENST00000547854
    miRNA
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    hsa-miR-520e hsa-miR-302d hsa-miR-429 hsa-miR-106a hsa-miR-218-1* hsa-miR-301a hsa-miR-766 hsa-miR-764
    SwitchGear 3'UTR luciferase reporter plasmid: POU6F1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for POU6F1
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POU6F1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU6F1

    Additional mRNA sequence: 

    AL832881.1 BC051326.1 BC074765.2 BC107090.1 L14482.1 NR_026893.1 Z21966.1 

    11 DOTS entries:

    DT.211139  DT.100019233  DT.92416809  DT.100719359  DT.121124774  DT.411233  DT.86852017  DT.100804567 
    DT.65284314  DT.95231668  DT.40200606 

    24/36 AceView cDNA sequences (see all 36):

    AF268617 Z21964 BV207798 CA503120 BV207801 AA205845 BV199669 BG569724 
    AU123692 CD247950 BV174940 CD247215 BM857157 CD048028 AA196616 CD049202 
    AW438879 AA176079 AA216545 CD048171 BM830060 AA232432 BQ278003 BM854645 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for POU6F1 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b
    SP1:                                      -                 -                                             
    SP2:                                                        -                                             
    SP3:                                                                                                      
    SP4:        -                             -                                                               
    SP5:                    -                                                                                 


    ECgene alternative splicing isoforms for POU6F1

    Expression
    for POU6F1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    POU6F1 expression in normal human tissues (normalized intensities)      POU6F1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGAAGGAA
    POU6F1 Expression
    About this image


    POU6F1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             ganglion/cranial/facial VII
     
     Spinal Cord (Nervous System)
             Primitive Spinal Cord

    See POU6F1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for POU6F1

    SOURCE GeneReport for Unigene cluster: Hs.555886

    UniProtKB/Swiss-Prot: PO6F1_HUMAN, Q14863
    Tissue specificity: In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression
    is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in
    specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum

        SABiosciences Custom PCR Arrays for POU6F1
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    In Situ
    Assay Products:     
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    Orthologs
    for POU6F1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for POU6F1 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Pou6f11 , 5 POU domain, class 6, transcription factor 11, 5 87.82(n)1
    95.35(a)1    		   15 (56.35 cM)5
    190091  NM_010127.31  NP_034257.11 
     1005753185 
    lizard
    (Anolis carolinensis)    		 Reptilia POU6F16
    		 Uncharacterized protein
    		 46(a)
    		 1 ↔ 1
    		 2(67512138-67531505)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.130062 Transcribed sequence with strong similarity to protein more 80(n)    BX724095.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii pouc2 POU domain gene C 73.53(n)   30334  NM_131113.1 


    ENSEMBL Gene Tree for POU6F1 (if available)
    TreeFam Gene Tree for POU6F1 (if available)

    Paralogs
    for POU6F1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for POU6F1 gene
    POU5F22  POU6F22  POU4F22  POU2F32  POU3F12  POU3F42  POU1F12  POU3F32  
    POU4F32  POU3F22  POU2F22  POU5F1B2  POU4F12  POU2F12  POU5F12  
    18/76 SIMAP similar genes for POU6F1 using alignment to 3 protein entries:     PO6F1_HUMAN (see all proteins) (see all similar genes):
    POU6F2    POU4F3    POU3F2    OCT6    POU3F1    OCT-2
    POU2F3    POU3F3    POU4F2    POU1F1    POU4F1    POU5F1B
    POU5F1P4    POU2F1    POU3F4    LHX9    POU2F2    EN2

    POU6F1 for paralogs           About GeneDecksing



    Genomic Variants
    for POU6F1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/608 SNPs in POU6F1 are shown (see all 608)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1922152461,2
    		--48626932(+) TGTAAA/GGACTG 1 -- us2k10--------
    rs107834181,2
    		C,F,A,H--51580219(+) GCTCTT/CATCAG 2 -- ds500123Minor allele frequency- C:0.46NS EA NA WA CSA 2342
    rs1430268841,2
    		C--51580225(+) ATCAGA/GCATCG 2 -- ds50010--------
    rs1913415261,2
    		--51580308(+) AGGCAC/TTGAGT 2 -- ds50010--------
    rs1165358301,2
    		C,F--51580459(+) CTAGGT/CATAAG 2 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1826330141,2
    		--51580468(+) AGAAGC/GGTGTT 2 -- ds50010--------
    rs1481952601,2
    		--51580618(+) TTTTCC/TAGGCT 2 -- ds50010--------
    rs111697521,2
    		C,F,A,H--51580707(+) GGAAAC/AAAGCA 2 -- ds500119Minor allele frequency- A:0.15NS EA NA CSA WA 2344
    rs1411889981,2
    		C--51580732(+) AAAAAA/TTACTG 2 -- ut31 nc-transcript-variant0--------
    rs769283551,2
    		C,F--51580947(+) AACTCG/ATGTGT 2 -- ut31 nc-transcript-variant1Minor allele frequency- A:0.05WA 118

    HapMap Linkage Disequilibrium report for POU6F1 (51580719 - 51611477 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for POU6F1 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2677962CNV Deletion23128226
    esv2745877CNV Deletion23290073
    esv2745881CNV Deletion23290073
    esv2239902CNV Deletion18987734
    esv2745878CNV Deletion23290073
    esv2745880CNV Deletion23290073
    esv2745879CNV Deletion23290073
    esv2745882CNV Deletion23290073
    nsv704CNV Insertion18451855
    esv1696566CNV Insertion17803354

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    Disorders / Diseases
    for POU6F1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    POU6F1 for disorders           About GeneDecksing

    2 diseases for POU6F1:    About MalaCards
    clear cell adenocarcinoma    adenocarcinoma

    1 disease from the University of Copenhagen DISEASES database for POU6F1:
    Clear cell adenocarcinoma

    Export disorders for POU6F1 gene to outside databases

    Publications
    for POU6F1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for POU6F1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with POU6F1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues. (PubMed id 7908264)1, 2, 3, 9 Wey E.... Schaefer B.W. (1994)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A novel POU domain protein which binds to the T-cell receptor beta enhancer. (PubMed id 8102789)1, 2 Messier H.... Fotedar A. (1993)
    4. Structure of human Brn-5 transcription factor in comp lex with CRH gene promoter. (PubMed id 19450691)1, 9 Pereira J.H. and Kim S.H. (2009)
    5. Crystallization and preliminary X-ray analysis of human Brn-5 transcription factor in complex with DNA. (PubMed id 18323601)1, 9 Pereira J.H....Kim S.H. (2008)
    6. Transcription factor POU6F1 is important for prolifer ation of clear cell adenocarcinoma of the ovary and is a potential new molecula r target. (PubMed id 20134265)1 Suzuki N....Ishizuka B. (2010)
    7. POU6F1 is the transcription factor that might be invo lved in cell proliferation of clear cell adenocarcinoma of the ovary. (PubMed id 19874398)1 Yoshioka N....Ishizuka B. (2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    External Searches for POU6F1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing POU6F1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5463 HGNC: 9224 AceView: LOC441628 Ensembl:ENSG00000184271 euGenes: HUgn5463
    ECgene: POU6F1 H-InvDB: POU6F1

    Other Databases showing POU6F1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing POU6F1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for POU6F1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for POU6F1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for POU6F1 gene:
    Search GeneIP for patents involving POU6F1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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