Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

POU5F2 Gene

protein-coding GIFtS: 38
GCID: GC05M093102

POU Domain Class 5, Transcription Factor 2

Search for POU5F2
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
POU Domain Class 5, Transcription Factor 2¹ ²
Sperm 1 POU Domain Transcription Factor² ³
SPRM-1² ³
POU Domain, Class 5, Transcription Factor 2²
SPRM1³

External Ids:	HGNC: 26367¹	Entrez Gene: 134187²	Ensembl: ENSG00000248483⁷	UniProtKB: Q8N7G0³

Export aliases for POU5F2 gene to outside databases

Previous GC identifer: GC05M088248

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for POU5F2 Gene:

POU5F2 (POU domain class 5, transcription factor 2) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU6F2.

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0

Function: Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a

regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NC_018916.2 NT_034772.6

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the POU5F2 gene promoter:
Spz1 IRF-1 HEN1 E2F E2F-1 HSF2 HOXA5 Cart-1 TGIF En-1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for POU5F2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU5F2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q15 Ensembl cytogenetic band: 5q15 HGNC cytogenetic band: 5q15

POU5F2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU5F2 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M093102: view genomic region (about GC identifiers)

Start:	93,070,508 bp from pter	End:	93,077,343 bp from pter
Size:	6,836 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0 (See protein sequence)

Recommended Name: POU domain, class 5, transcription factor 2

Size: 328 amino acids; 36051 Da

Subcellular location: Nucleus (By similarity)

Secondary accessions: Q15169 Q6MZL7 Q8N748

Explore the universe of human proteins at neXtProt for POU5F2: NX_Q8N7G0

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q8N7G0

POU5F2 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : --

REFSEQ proteins: NP_694948.1

ENSEMBL proteins:

ENSP00000464890

Human Recombinant Protein Products for POU5F2:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for POU5F2 OriGene Custom MassSpec OriGene Custom Protein Services for POU5F2
	GenScript Custom Purified and Recombinant Proteins Services for POU5F2
	Novus Biologicals POU5F2 Proteins Novus Biologicals POU5F2 Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for POU5F2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

POU5F2 for ontologies About GeneDecksing

POU5F2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for POU5F2
	GenScript Custom Superior Antibodies Services for POU5F2
	Novus Biologicals POU5F2 Antibodies
	Abcam antibodies for POU5F2
	Cloud-Clone Corp. Antibodies for POU5F2
	Search ThermoFisher Antibodies for POU5F2
	LSBio Antibodies in human, mouse, rat for POU5F2

Assay Products for POU5F2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for POU5F2
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for POU5F2
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for POU5F2 Cloud-Clone Corp. CLIAs for POU5F2

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

POU: Homeoboxes / POU class

5 InterPro protein domains:

IPR010982 Lambda_DNA-bd_dom

IPR013847 POU

IPR000327 POU_specific

IPR001356 Homeodomain

IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry Q8N7G0

ProtoNet protein and cluster: Q8N7G0

2 Blocks protein domains:

IPB000327 POU domain

IPB013847 POU

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0

Similarity: Belongs to the POU transcription factor family. Class-5 subfamily

Similarity: Contains 1 homeobox DNA-binding domain

Similarity: Contains 1 POU-specific domain

POU5F2 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: PO5F2_HUMAN, Q8N7G0

Function: Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a

regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By

similarity)

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	--	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

POU5F2 for ontologies About GeneDecksing

Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Pou5f2):

behavior/neurological

reproductive system

POU5F2 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Pou5f2^tm1Rsd for POU5F2

inGenious Targeting Laboratory - Custom generated mouse model solutions for POU5F2

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for POU5F2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for POU5F2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for POU5F2

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POU5F2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate POU5F2
		SwitchGear 3'UTR luciferase reporter plasmid: POU5F2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for POU5F2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POU5F2

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for POU5F2
			Sirion Biotech Customized adenovirus for overexpression of POU5F2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for POU5F2 (see all 6) OriGene ORF clones in mouse, rat for POU5F2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: POU5F2 (NM_153216)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for POU5F2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU5F2
		Sirion Biotech Customized lentivirus for stable overexpression of POU5F2 Customized lentivirus expression plasmids for stable overexpression of POU5F2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for POU5F2
		Search LifeMap BioReagents cell lines for POU5F2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU5F2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for POU5F2

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	--	--

POU5F2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for POU5F2 (PO5F2)

Search CenterWatch for drugs/clinical trials and news about POU5F2 / PO5F2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for POU5F2 gene:

NM_153216.1

Unigene Cluster for POU5F2:

POU domain class 5, transcription factor 2

Hs.678995 [show with all ESTs]

Unigene Representative Sequence: BX641019

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000606183 ENST00000510627(uc003kkl.1)

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POU5F2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate POU5F2
		SwitchGear 3'UTR luciferase reporter plasmid: POU5F2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for POU5F2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POU5F2

Clone Products:		OriGene clones in human, mouse for POU5F2 (see all 6) OriGene ORF clones in mouse, rat for POU5F2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: POU5F2 (NM_153216)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for POU5F2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU5F2
		Sirion Biotech Customized lentivirus for stable overexpression of POU5F2 Customized lentivirus expression plasmids for stable overexpression of POU5F2

Primer Products:		OriGene qPCR primer pairs and template standards for POU5F2 OriGene qSTAR qPCR primer pairs in human, mouse for POU5F2
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat POU5F2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POU5F2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU5F2

Additional mRNA sequence:

AK097970.1 AK098546.1 BC029532.1 BX641019.1 Z21965.1

2 DOTS entries:

DT.92023537 DT.100009090

12 AceView cDNA sequences:

NM_153216 Z21965 AK097970 BC029532 AK098546 BQ709766 BX641019 BI559739

BF979742 BP369993 BF980039 AV761918

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

POU5F2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TGGAAGCTGC

About this image

Genevestigator expression for POU5F2

SOURCE GeneReport for Unigene cluster: Hs.678995

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0

Tissue specificity: Expressed in skeletal and cardiac muscles, brain, heart and lung. Little or no detectable

expression found in pancreas, kidney, liver or placenta

SABiosciences Custom PCR Arrays for POU5F2

Primer Products:		OriGene qPCR primer pairs and template standards for POU5F2 OriGene qSTAR qPCR primer pairs in human, mouse for POU5F2
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat POU5F2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POU5F2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU5F2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU5F2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for POU5F2 gene from 10 species (see representative species ) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chimpanzee (Pan troglodytes)	Mammalia	POU5F2¹	POU domain class 5, transcription factor 2	98.88(n) 97.56(a)		737314 XM_001139199.2 XP_001139199.1
mouse (Mus musculus)	Mammalia	Pou5f2^{1 , 5}	POU domain class 5, transcription factor 2^{1, 5}	77.11(n)¹ 69.3(a)¹		13 (41.38 cM)⁵ 75507¹ NM_029315.1¹ NP_083591.1¹ 78022913⁵
rat (Rattus norvegicus)	Mammalia	Pou5f2¹	POU domain class 5, transcription factor 2	76.92(n) 68.32(a)		680620 NM_001081751.1 NP_001075220.1
oppossum (Monodelphis domestica)	Mammalia	-- --	Uncharacterized protein	50(a) 21(a)	1 ↔ many possible ortholog	2(267419431-267422270) 1(469389193-469422029)
platypus (Ornithorhynchus anatinus)	Mammalia	POU5F1⁶	POU domain, class 5, transcription factor 1	41(a)	1 → many	Contig22957(15451-15985)
chicken (Gallus gallus)	Aves	POUV⁶	POU domain class 5 transcription factor 1	29(a)	possible ortholog	17(460123-461472)
lizard (Anolis carolinensis)	Reptilia	--	Uncharacterized protein	36(a)	1 → many	GL343623.1(305510-323263)
zebrafish (Danio rerio)	Actinopterygii	pou5f1⁶	POU domain, class 5, transcription factor 1	20(a)	possible ortholog	21(11887950-11892809)
sea squirt (Ciona savignyi)	Ascidiacea	CSA.1093⁶	Uncharacterized protein	9(a)	1 → many	reftig_41(1314919-1326878)
worm (Caenorhabditis elegans)	Secernentea	ceh-18⁶	Homeobox protein ceh-18	13(a)	1 → many	X(3843827-3857797)

Species with no ortholog for POU5F2

ENSEMBL Gene Tree for POU5F2 (if available)
TreeFam Gene Tree for POU5F2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for POU5F2 gene

POU6F2² POU4F2² POU2F3² POU3F1² POU3F4² POU1F1² POU3F3² POU4F3²

POU3F2² POU2F2² POU5F1B² POU4F1² POU2F1² POU6F1² POU5F1²

6 SIMAP similar genes for POU5F2 using alignment to 1 protein entry: PO5F2_HUMAN:

POU6F1 POU5F1P4 POU5F1 POU5F1B POU5F1P1 POU3F4

POU5F2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POU5F2

DNA2.0 Custom Variant and Variant Library Synthesis for POU5F2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for POU5F2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with POU5F2)

Utopia: connect your pdf to the dynamic
world of online information

A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues. (PubMed id 7908264)^{1, 2, 3} Wey E.... Schaefer B.W. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 134187	HGNC: 26367	AceView: FLJ25680	Ensembl:ENSG00000248483	euGenes: HUgn134187
ECgene: POU5F2	H-InvDB: POU5F2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for POU5F2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for POU5F2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for POU5F2 gene:
Search GeneIP for patents involving POU5F2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for POU5F2
	OriGene qPCR primer pairs and template standards for POU5F2		OriGene Protein Over-expression Lysate for POU5F2
	OriGene Custom Mass Spec		OriGene clones in human, mouse for POU5F2
	OriGene qSTAR qPCR primer pairs in human, mouse for POU5F2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for POU5F2		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for POU5F2		OriGene Custom Protein Services for POU5F2

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POU5F2
	Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POU5F2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU5F2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POU5F2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU5F2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POU5F2

	GenScript Custom Purified and Recombinant Proteins Services for POU5F2		GenScript cDNA clones with any tag delivered in your preferred vector for POU5F2
	GenScript Custom Assay Services for POU5F2		GenScript Custom Superior Antibodies Services for POU5F2
	GenScript Custom overexpressing Cell Line Services for POU5F2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in POU5F2 promoter
	Search Chromatin IP Primers for POU5F2
	RT² qPCR Primer Assay in human, mouse, rat POU5F2
	Search GNC Networks for POU5F2
	SABiosciences Custom PCR Arrays for POU5F2

Search Tocris compounds for POU5F2 (PO5F2)

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	POU5F2 antibodies
	POU5F2 proteins
	POU5F2 lysates

	Antibodies for POU5F2
	See all of Abcam's Antibodies, Kits and Proteins for POU5F2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for POU5F2
	Antibodies for POU5F2
	ELISAs for POU5F2
	CLIAs for POU5F2

Search LifeMap BioReagents cell lines for POU5F2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU5F2

	SwitchGear 3'UTR luciferase reporter plasmids for POU5F2
	Browse SwitchGear Promoter luciferase reporter plasmids for POU5F2

Search ThermoFisher Antibodies for POU5F2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU5F2

	inGenious Targeting Laboratory - Custom generated mouse model solutions for POU5F2
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for POU5F2

Customized:

	lentivirus for stable overexpression of POU5F2
	lentivirus expression plasmids for stable overexpression of POU5F2
	adenovirus for overexpression of POU5F2

LSBio Antibodies in human, mouse, rat for POU5F2

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes POU5F2 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

POU5F2 Gene

POU Domain Class 5, Transcription Factor 2

Aliases
for POU5F2 gene

Summaries
for POU5F2 gene

Genomic Views
for POU5F2 gene

Proteins
for POU5F2 gene

Protein Domains /
Families
for POU5F2 gene

Function
for POU5F2 gene

Pathways & Interactions
for POU5F2 gene

Drugs & Compounds
for POU5F2 gene

Transcripts
for POU5F2 gene

Expression
for POU5F2 gene

Orthologs
for POU5F2 gene

Paralogs
for POU5F2 gene

Genomic Variants
for POU5F2 gene

Disorders / Diseases
for POU5F2 gene

Publications
for POU5F2 gene

External Searches for POU5F2 gene

Genome Databases showing POU5F2 gene

Other Databases showing POU5F2 gene

Specialized Databases showing POU5F2 gene

Intellectual Property
for POU5F2 gene

Products
for POU5F2 gene

View Random Gene

Advanced Search

Export list of displayed genes

POU5F2 Gene

POU Domain Class 5, Transcription Factor 2

Aliasesfor POU5F2 gene

Summariesfor POU5F2 gene

Genomic Viewsfor POU5F2 gene

Proteinsfor POU5F2 gene

Protein Domains /Familiesfor POU5F2 gene

Functionfor POU5F2 gene

Pathways & Interactionsfor POU5F2 gene

Drugs & Compoundsfor POU5F2 gene

Transcriptsfor POU5F2 gene

Expression for POU5F2 gene

Orthologsfor POU5F2 gene

Paralogsfor POU5F2 gene

Genomic Variantsfor POU5F2 gene

Disorders / Diseasesfor POU5F2 gene

Publicationsfor POU5F2 gene

External Searches for POU5F2 gene

Genome Databases showing POU5F2 gene

Other Databases showing POU5F2 gene

Specialized Databases showing POU5F2 gene

Intellectual Propertyfor POU5F2 gene

Productsfor POU5F2 gene

View Random Gene

Aliases
for POU5F2 gene

Summaries
for POU5F2 gene

Genomic Views
for POU5F2 gene

Proteins
for POU5F2 gene

Protein Domains /
Families
for POU5F2 gene

Function
for POU5F2 gene

Pathways & Interactions
for POU5F2 gene

Drugs & Compounds
for POU5F2 gene

Transcripts
for POU5F2 gene

Expression
for POU5F2 gene

Orthologs
for POU5F2 gene

Paralogs
for POU5F2 gene

Genomic Variants
for POU5F2 gene

Disorders / Diseases
for POU5F2 gene

Publications
for POU5F2 gene

Intellectual Property
for POU5F2 gene

Products
for POU5F2 gene