Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Plus
- Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

POU5F2 Gene

protein-coding GIFtS: 32
GCID: GC05M093102

POU Domain Class 5, Transcription Factor 2

Search for POU5F2
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

TryGeneCards Plus

Aliases
POU Domain Class 5, Transcription Factor 2¹ ²
Sperm 1 POU Domain Transcription Factor² ³
SPRM-1² ³
POU Domain, Class 5, Transcription Factor 2²
SPRM1³

External Ids:	HGNC: 26367¹	Entrez Gene: 134187²	Ensembl: ENSG00000248483⁷	UniProtKB: Q8N7G0³

Export aliases for POU5F2 gene to outside databases

Previous GC identifer: GC05M088248

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for POU5F2 Gene:

POU5F2 (POU domain class 5, transcription factor 2) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU6F2.

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0

Function: Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a

regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By

similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus

Regulatory elements:

Regulatory transcription factor binding sites in the POU5F2 gene promoter:
Spz1 IRF-1 HEN1 E2F E2F-1 HSF2 HOXA5 Cart-1 TGIF En-1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search Chromatin IP Primers for POU5F2

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU5F2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q15 Ensembl cytogenetic band: 5q15 HGNC cytogenetic band: 5q15

POU5F2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU5F2 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M093102: view genomic region (about GC identifiers)

Start:	93,070,508 bp from pter	End:	93,077,343 bp from pter
Size:	6,836 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0 (See protein sequence)

Recommended Name: POU domain, class 5, transcription factor 2

Size: 328 amino acids; 36051 Da

Secondary accessions: Q15169 Q6MZL7 Q8N748

Explore the universe of human proteins at neXtProt for POU5F2: NX_Q8N7G0

REFSEQ proteins: NP_694948.1

ENSEMBL proteins:

ENSP00000464890

POU5F2 Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for POU5F2 OriGene Custom MassSpec OriGene Custom Protein Services for POU5F2
	GenScript Custom Purified and Recombinant Proteins Services for POU5F2
	Novus Biologicals POU5F2 Proteins Novus Biologicals POU5F2 Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for POU5F2

POU5F2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for POU5F2
	Novus Biologicals POU5F2 Antibodies
	Search for Antibodies for POU5F2 at Abcam
	Cloud-Clone Corp. Antibodies for POU5F2
	Search ThermoFisher Antibodies for POU5F2
	LSBio Antibodies in human, mouse, rat for POU5F2

POU5F2 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for POU5F2
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for POU5F2
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for POU5F2 Cloud-Clone Corp. CLIAs for POU5F2

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

HGNC Gene Families:

POU: Homeoboxes / POU class

5 InterPro protein domains:

IPR010982 Lambda_DNA-bd_dom

IPR013847 POU

IPR000327 POU_specific

IPR001356 Homeobox_dom

IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry Q8N7G0

ProtoNet protein and cluster: Q8N7G0

2 Blocks protein domains:

IPB000327 POU domain

IPB013847 POU

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0

Similarity: Belongs to the POU transcription factor family. Class-5 subfamily

Similarity: Contains 1 homeobox DNA-binding domain

Similarity: Contains 1 POU-specific domain

POU5F2 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

UniProtKB/Swiss-Prot Summary: PO5F2_HUMAN, Q8N7G0

Function: Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a

regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By

similarity)

Gene Ontology (GO): 3 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	--	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

POU5F2 for ontologies About GeneDecksing

Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Pou5f2):

behavior/neurological

reproductive system

POU5F2 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Pou5f2^tm1Rsd for POU5F2

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POU5F2

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for POU5F2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for POU5F2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for POU5F2

miRNA Products:		Block miRNA regulation of human, mouse, rat POU5F2 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate POU5F2
		SwitchGear 3'UTR luciferase reporter plasmid: POU5F2 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for POU5F2
		Predesigned siRNA for gene silencing in human, mouse, rat POU5F2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for POU5F2

Clone Products:		OriGene clones in human, mouse for POU5F2 (see all 5) OriGene ORF clones in mouse, rat for POU5F2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: POU5F2 (NM_153216)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for POU5F2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU5F2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for POU5F2
		Browse ESI BIO Cell Lines and PureStem Progenitors for POU5F2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU5F2

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot

PO5F2_HUMAN, Q8N7G0: Nucleus (By similarity)

Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

POU5F2 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for POU5F2
Interactions:

Search GeneGlobe Interaction Network for POU5F2

Gene Ontology (GO): 2 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-templated	IEA	--
GO:0006355	regulation of transcription, DNA-templated	--	--

POU5F2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for POU5F2 (PO5F2)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for POU5F2 gene:

NM_153216.1

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000606183 ENST00000510627(uc003kkl.1)

miRNA Products:		Block miRNA regulation of human, mouse, rat POU5F2 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate POU5F2
		SwitchGear 3'UTR luciferase reporter plasmid: POU5F2 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for POU5F2
		Predesigned siRNA for gene silencing in human, mouse, rat POU5F2

Clone Products:		OriGene clones in human, mouse for POU5F2 (see all 5) OriGene ORF clones in mouse, rat for POU5F2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: POU5F2 (NM_153216)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for POU5F2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU5F2

Primer Products:		OriGene qPCR primer pairs and template standards for POU5F2 OriGene qSTAR qPCR primer pairs in human, mouse for POU5F2
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat POU5F2
		QuantiTect SYBR Green Assays in human, mouse, rat POU5F2
		QuantiFast Probe-based Assays in human, mouse, rat POU5F2

12 AceView cDNA sequences:

AK097970 Z21965 NM_153216 AK098546 BQ709766 BC029532 BX641019 BI559739

BP369993 BF979742 BF980039 AV761918

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

POU5F2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TGGAAGCTGC

About this image

POU5F2 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 2) fully expand


Testis (Reproductive System)
Secondary Spermatocyte Seminiferous Tubules

Gonad
Secondary Spermatocyte Seminiferous Tubules

POU5F2 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

UniProtKB/Swiss-Prot: PO5F2_HUMAN, Q8N7G0

Tissue specificity: Expressed in skeletal and cardiac muscles, brain, heart and lung. Little or no detectable

expression found in pancreas, kidney, liver or placenta

Custom PCR Arrays for POU5F2

Primer Products:		OriGene qPCR primer pairs and template standards for POU5F2 OriGene qSTAR qPCR primer pairs in human, mouse for POU5F2
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat POU5F2
		QuantiTect SYBR Green Assays in human, mouse, rat POU5F2
		QuantiFast Probe-based Assays in human, mouse, rat POU5F2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU5F2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of animals.

Orthologs for POU5F2 gene from 12 species (see representative species ) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chimpanzee (Pan troglodytes)	Mammalia	POU5F2¹	POU domain class 5, transcription factor 2	98.88(n) 97.56(a)		737314 XM_001139199.2 XP_001139199.1
mouse (Mus musculus)	Mammalia	Pou5f2^{1 , 5}	POU domain class 5, transcription factor 2^{1, 5}	75.5(n)¹ 67.19(a)¹		13 (41.38 cM)⁵ 75507¹ NM_029315.1¹ NP_083591.1¹ 78024902⁵
rat (Rattus norvegicus)	Mammalia	Pou5f2¹	POU domain class 5, transcription factor 2	76.88(n) 68.11(a)		680620 NM_001081751.1 NP_001075220.1
cow (Bos taurus)	Mammalia	POU5F1⁶	Bos taurus POU class 5 homeobox 1 (POU5F1), mRNA.	46(a)	many ↔ many	23(27769893-27774392)
dog (Canis familiaris)	Mammalia	--	Uncharacterized protein	46(a)	1 → many	12(861374-866099)
oppossum (Monodelphis domestica)	Mammalia	--	Uncharacterized protein	50(a)	1 → many	2(267419431-267422270)
chicken (Gallus gallus)	Aves	POUV⁶	Gallus gallus POU domain class 5 transcription fac...	28(a)	1 → many	17(460123-461472)
lizard (Anolis carolinensis)	Reptilia	--	Uncharacterized protein	36(a)	1 → many	GL343623.1(305510-323263)
zebrafish (Danio rerio)	Actinopterygii	zgc:158291⁶	zgc:158291	22(a)	many ↔ many	21(37272808-37275500) ENSDARG00000044375
sea squirt (Ciona savignyi)	Ascidiacea	--	Uncharacterized protein	16(a)	1 → many	reftig_19(4764818-4767613)
fruit fly (Drosophila melanogaster)	Insecta	acj6⁶	abnormal chemosensory jump 6	18(a)	1 → many	X(15245315-15272487)
worm (Caenorhabditis elegans)	Secernentea	unc-86⁶	Protein UNC-86, isoform a (unc-86) mRNA, complete ...	19(a)	1 → many	III(8212758-8216336) WBGene00006818

Species with no ortholog for POU5F2

ENSEMBL Gene Tree for POU5F2 (if available)
TreeFam Gene Tree for POU5F2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

TryGeneCards Plus

Paralogs for POU5F2 gene

POU6F2² POU4F2² POU2F3² POU3F1² POU3F4² POU1F1² POU3F3² POU4F3²

POU3F2² POU2F2² POU5F1B² POU4F1² POU2F1² POU6F1² POU5F1²

6 SIMAP similar genes for POU5F2 using alignment to 1 protein entry: PO5F2_HUMAN:

POU6F1 POU5F1P4 POU5F1 POU5F1B POU5F1P1 POU3F4

POU5F2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Site Specific Mutation Identification with PCR Assays

Search QIAGEN SeqTarget long-range PCR primers for resequencing POU5F2

DNA2.0 Custom Variant and Variant Library Synthesis for POU5F2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for POU5F2 gene integrated from 10 sources:
(articles sorted by number of sources associating them with POU5F2)

Utopia: connect your pdf to the dynamic
world of online information

A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues. (PubMed id 7908264)^{1, 2, 3} Wey E.... Schaefer B.W. (Eur. J. Biochem. 1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (BMC Genomics 2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus

Entrez Gene: 134187	HGNC: 26367	AceView: FLJ25680	Ensembl:ENSG00000248483	euGenes: HUgn134187
ECgene: POU5F2	H-InvDB: POU5F2

(According to HUGE)
About This Section

TryGeneCards Plus

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus

Name	Description
PharmGKB entry for POU5F2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for POU5F2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

TryGeneCards Plus

Patent Information for POU5F2 gene:
Search GeneIP for patents involving POU5F2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for POU5F2
	OriGene qPCR primer pairs and template standards for POU5F2		OriGene Protein Over-expression Lysate for POU5F2
	OriGene Custom Mass Spec		OriGene clones in human, mouse for POU5F2
	OriGene qSTAR qPCR primer pairs in human, mouse for POU5F2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for POU5F2		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for POU5F2		OriGene Custom Protein Services for POU5F2

	Block miRNA regulation of human, mouse, rat POU5F2 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing POU5F2
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU5F2		Predesigned siRNA for gene silencing in human, mouse, rat POU5F2
	QuantiFast Probe-based Assays in human, mouse, rat POU5F2		QuantiTect SYBR Green Assays in human, mouse, rat POU5F2
	Custom PCR Arrays for POU5F2		Search Chromatin IP Primers for POU5F2
	Pre-validated RT² qPCR Primer Assay in human, mouse, rat POU5F2		Search GeneGlobe Interaction Network for POU5F2
	Regulatory tfbs in POU5F2 promoter

	GenScript Custom Purified and Recombinant Proteins Services for POU5F2		GenScript cDNA clones with any tag delivered in your preferred vector for POU5F2
	GenScript Custom Assay Services for POU5F2		GenScript Custom overexpressing Cell Line Services for POU5F2
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for POU5F2 (PO5F2)

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	POU5F2 antibodies
	POU5F2 proteins
	POU5F2 lysates

	Search for Antibodies for POU5F2 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for POU5F2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for POU5F2
	Antibodies for POU5F2
	ELISAs for POU5F2
	CLIAs for POU5F2

Browse ESI BIO Cell Lines and PureStem Progenitors for POU5F2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU5F2

	SwitchGear 3'UTR luciferase reporter plasmids for POU5F2
	Browse SwitchGear Promoter luciferase reporter plasmids for POU5F2

Search ThermoFisher Antibodies for POU5F2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU5F2

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POU5F2
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for POU5F2

LSBio Antibodies in human, mouse, rat for POU5F2

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

Browse compounds at ApexBio

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes POU5F2 gene at Home site.

Version: 3.12.142 28 July 2014
hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4

GeneCards Plus

Advanced Search

Export list of displayed genes

POU5F2 Gene

POU Domain Class 5, Transcription Factor 2

Aliases
for POU5F2 gene

Summaries
for POU5F2 gene

Genomic Views
for POU5F2 gene

Proteins
for POU5F2 gene

POU5F2 Human Recombinant Protein Products:

POU5F2 Antibody Products:

POU5F2 Assay Products:

Domains /
Families
for POU5F2 gene

Function
for POU5F2 gene

Localization
for POU5F2 gene

Pathways & Interactions
for POU5F2 gene

Drugs & Compounds
for POU5F2 gene

Transcripts
for POU5F2 gene

Expression
for POU5F2 gene

Orthologs
for POU5F2 gene

Paralogs
for POU5F2 gene

Genomic Variants
for POU5F2 gene

Disorders / Diseases
for POU5F2 gene

Publications
for POU5F2 gene

External Searches for POU5F2 gene

Genome Databases showing POU5F2 gene

Other Databases showing POU5F2 gene

Specialized Databases showing POU5F2 gene

Intellectual Property
for POU5F2 gene

Products
for POU5F2 gene

View Random Gene

GeneCards Plus

Advanced Search

Export list of displayed genes

POU5F2 Gene

POU Domain Class 5, Transcription Factor 2

Aliasesfor POU5F2 gene

Summariesfor POU5F2 gene

Genomic Viewsfor POU5F2 gene

Proteinsfor POU5F2 gene

POU5F2 Human Recombinant Protein Products:

POU5F2 Antibody Products:

POU5F2 Assay Products:

Domains /Familiesfor POU5F2 gene

Functionfor POU5F2 gene

Localizationfor POU5F2 gene

Pathways & Interactionsfor POU5F2 gene

Drugs & Compoundsfor POU5F2 gene

Transcriptsfor POU5F2 gene

Expression for POU5F2 gene

Orthologsfor POU5F2 gene

Paralogsfor POU5F2 gene

Genomic Variantsfor POU5F2 gene

Disorders / Diseasesfor POU5F2 gene

Publicationsfor POU5F2 gene

External Searches for POU5F2 gene

Genome Databases showing POU5F2 gene

Other Databases showing POU5F2 gene

Specialized Databases showing POU5F2 gene

Intellectual Propertyfor POU5F2 gene

Productsfor POU5F2 gene

View Random Gene

Aliases
for POU5F2 gene

Summaries
for POU5F2 gene

Genomic Views
for POU5F2 gene

Proteins
for POU5F2 gene

Domains /
Families
for POU5F2 gene

Function
for POU5F2 gene

Localization
for POU5F2 gene

Pathways & Interactions
for POU5F2 gene

Drugs & Compounds
for POU5F2 gene

Transcripts
for POU5F2 gene

Expression
for POU5F2 gene

Orthologs
for POU5F2 gene

Paralogs
for POU5F2 gene

Genomic Variants
for POU5F2 gene

Disorders / Diseases
for POU5F2 gene

Publications
for POU5F2 gene

Intellectual Property
for POU5F2 gene

Products
for POU5F2 gene