Aliases for POU5F1B Gene
External Ids for POU5F1B Gene
Previous HGNC Symbols for POU5F1B Gene
Previous GeneCards Identifiers for POU5F1B Gene
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development. [provided by RefSeq, Apr 2009]
GeneCards Summary for POU5F1B Gene
POU5F1B (POU Class 5 Homeobox 1B) is a Protein Coding gene. Diseases associated with POU5F1B include Mature Teratoma and Malignant Teratoma. Among its related pathways are Signaling pathways regulating pluripotency of stem cells. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is POU6F1.
UniProtKB/Swiss-Prot for POU5F1B Gene
Shows weak transcriptional activator activity.