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POU5F1B Gene

protein-coding   GIFtS: 44
GCID: GC08P128426

POU Class 5 Homeobox 1B

(Previous names: POU domain class 5, transcription factor 1 pseudogene 1,...)
(Previous symbols: OTF3P1, POU5F1P1)
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Aliases
for POU5F1B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
POU Class 5 Homeobox 1B1 2     POU5F1P42
OTF3P11 2 3     Octamer Binding Protein 3_like Sequence2
POU5F1P11 2 3     POU 5 Domain Protein2
POU Class 5 Homeobox 1 Pseudogene 11 2     POU Domain Transcription Factor Oct-42
OTF3C2 3     POU Domain Transcription Factor OCT4-Pg12
POU5FLC202 3     POU Domain, Class 5, Transcription Factor 1 Pseudogene 12
POU5FLC82 3     Putative POU Domain, Class 5, Transcription Factor 1B2
POU Domain Class 5, Transcription Factor 1 Pseudogene 11     Octamer-Binding Protein 3-Like3
OCT4-PG12     Octamer-Binding Transcription Factor 3-Like3

External Ids:    HGNC: 92231   Entrez Gene: 54622   Ensembl: ENSG000002129937   UniProtKB: Q064163   

Export aliases for POU5F1B gene to outside databases

Previous GC identifers: GC08P128499 GC08P123746


Summaries
for POU5F1B gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for POU5F1B Gene:
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been
reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and
highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional
activator and may play a role in carcinogenesis and eye development. (provided by RefSeq, Apr 2009)

GeneCards Summary for POU5F1B Gene:
POU5F1B (POU class 5 homeobox 1B) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: P5F1B_HUMAN, Q06416
Function: Shows weak transcriptional activator activity




Genomic Views
for POU5F1B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_008046.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the POU5F1B gene promoter:
         STAT5B   AML1a   Pbx1a   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   CUTL1   Cdc5   POU3F2   Gfi-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for POU5F1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU5F1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.21   Ensembl cytogenetic band:  8q24.21   HGNC cytogenetic band: 8q24.21

POU5F1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU5F1B gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P128426:  view genomic region     (about GC identifiers)

Start:
 128,426,535 bp from pter      End:
 128,432,311 bp from pter
Size:
 5,777 bases      Orientation:
 plus strand

Proteins
for POU5F1B gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: P5F1B_HUMAN, Q06416 (See protein sequence)
Recommended Name: Putative POU domain, class 5, transcription factor 1B  
Size: 359 amino acids; 38588 Da
Caution: Could be the product of a pseudogene. Several pseudogenes of POU5F1 have been described on chromosomes 1,
3, 8, 10 and 12. Two of them, localized on chromosomes 8 and 10 have been shown to be preferentially transcribed
in cancer tissues and may be involved in the regulation of POU5F1 gene activity in carcinogenesis
Secondary accessions: D5K9V4 Q2VIK6 Q9BZV7 Q9BZV9

Explore the universe of human proteins at neXtProt for POU5F1B: NX_Q06416

Explore proteomics data for POU5F1B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See POU5F1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001153014.1  
    ENSEMBL proteins: 
     ENSP00000419298   ENSP00000375557  

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    Domains /
    Families
    for POU5F1B gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 HGNC Gene Families:
    POU: Homeoboxes / POU class

    Selected InterPro protein domains (see all 7):
     IPR010982 Lambda_DNA-bd_dom
     IPR013847 POU
     IPR000327 POU_specific
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom

    Graphical View of Domain Structure for InterPro Entry Q06416

    ProtoNet protein and cluster: Q06416

    2 Blocks protein domains:
    IPB000327 POU domain
    IPB013847 POU


    UniProtKB/Swiss-Prot: P5F1B_HUMAN, Q06416
    Similarity: Belongs to the POU transcription factor family. Class-5 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 POU-specific domain


    Find genes that share domains with POU5F1B           About GenesLikeMe


    Function
    for POU5F1B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: P5F1B_HUMAN, Q06416
    Function: Shows weak transcriptional activator activity

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity TAS1408763
    GO:0043565sequence-specific DNA binding IEA--
         
    Find genes that share ontologies with POU5F1B           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for POU5F1B

    miRNA
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    Gene Editing
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    Localization
    for POU5F1B gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    P5F1B_HUMAN, Q06416: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with POU5F1B           About GenesLikeMe


    Pathways & Interactions
    for POU5F1B gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for POU5F1B
    Interactions:

        Search GeneGlobe Interaction Network for POU5F1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for POU5F1B (ENSP000003755574) via UniProtKB, MINT, STRING, and/or I2D (see all 60)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NANOGENSP000002293074STRING: ENSP00000229307
    ARID3BENSP000003431264STRING: ENSP00000343126
    GATAD2BENSP000003576444STRING: ENSP00000357644
    MTA2ENSP000002788234STRING: ENSP00000278823
    MTA1ENSP000003336334STRING: ENSP00000333633
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS1408763

    Find genes that share ontologies with POU5F1B           About GenesLikeMe



    Drugs & Compounds
    for POU5F1B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for POU5F1B (P5F1B)



    Transcripts
    for POU5F1B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for POU5F1B gene: 
    NM_001159542.1  

    Unigene Cluster for POU5F1B:

    POU class 5 homeobox 1B
    Hs.450254  [show with all ESTs]
    Unigene Representative Sequence: DQ486513
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000465342 ENST00000391675(uc003ysf.3)
    miRNA
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    Additional mRNA sequence: 

    AF268615.1 AF268618.1 DQ486513.1 FM177969.1 FM177970.1 FM177971.1 FM177972.1 FM177973.1 
    FM177974.1 FM177975.1 FM177976.1 FM177977.1 FM177978.1 FM177979.1 FM177980.1 FM177981.1 
    FM177982.1 

    2 DOTS entries:

    DT.100791937  DT.75142423 

    Selected AceView cDNA sequences (see all 32):

    AF268615 BX108223 AF268618 BV207915 CB144537 BM817496 BV207913 BV199595 
    BM796771 BV207916 BV207917 CD247012 AA196616 BM857157 CD049748 CD049560 
    BG656494 BV199596 AA480280 CD048739 AA232432 BM830060 BV199667 AA515288 

    GeneLoc Exon Structure


    Expression
    for POU5F1B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    POU5F1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    POU5F1B Expression
    About this image


    POU5F1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 14 entries
             hIPS1
             ESI-051   
     
     NULL (Uncategorized)
             Mesenchymal Progenitor Cells - Passage 2
    POU5F1B Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    POU5F1B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.450254
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    Orthologs
    for POU5F1B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for POU5F1B gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves POUV6
    		 Gallus gallus POU domain class 5 transcription fac...
    		 39(a)
    		 1 → many
    		 17(460123-461472)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 Uncharacterized protein
    		 55(a)
    		 1 → many
    		 GL343623.1(305510-323263)
    zebrafish
    (Danio rerio)    		 Actinopterygii pou5f36
    		 POU domain, class 5, transcription factor 3
    		 28(a)
    		 1 → many
    		 21(11887950-11892809) ENSDARG00000044774
    fruit fly
    (Drosophila melanogaster)    		 Insecta acj66
    		 abnormal chemosensory jump 6
    		 22(a)
    		 1 → many
    		 X(15245315-15272487)
    worm
    (Caenorhabditis elegans)    		 Secernentea unc-866
    		 Protein UNC-86, isoform a (unc-86) mRNA, complete ...
    		 25(a)
    		 1 → many
    		 III(8212758-8216336) WBGene00006818
            Species with no ortholog for POU5F1B

    ENSEMBL Gene Tree for POU5F1B (if available)
    TreeFam Gene Tree for POU5F1B (if available)

    Paralogs
    for POU5F1B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for POU5F1B gene
    POU5F22  POU6F22  POU4F22  POU2F32  POU3F12  POU3F42  POU1F12  POU3F32  
    POU4F32  POU3F22  POU2F22  POU4F12  POU2F12  POU6F12  POU5F12  
    12 SIMAP similar genes for POU5F1B using alignment to 1 protein entry:     P5F1B_HUMAN:
    POU5F1P1    POU5F1    POU5F1P3    POU5F1P4    POU6F1    POU3F4
    POU5F2    POU1F1    POU2F2    POU2F1    POU3F2    POU3F1

    Find genes that share paralogs with POU5F1B           About GenesLikeMe



    Genomic Variants
    for POU5F1B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for POU5F1B (see all 116)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 8 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs796112401,2
    		C,F--128425906(+) AAGCAG/AAGCAT 1 -- us2k11Minor allele frequency- A:0.01MN 156
    rs1419396211,2
    		--128425919(+) CCTCAA/GACGAT 1 -- us2k10--------
    rs800553061,2
    		C,F--128426003(+) ACTTTT/ACTGCT 1 -- us2k11Minor allele frequency- A:0.04EA 120
    rs2017539801,2
    		--128426100(+) AGGTG-/GTGTACA 1 -- us2k10--------
    rs751701461,2
    		C--128426103(+) GTGGTA/GCACAC 1 -- us2k10--------
    rs39997761,2
    		C--128426125(+) acaca-/CA/   
      CACACA    NNNNN     		2 -- us2k1 cds11NA 2
    rs780982571,2
    		C,F--128426196(+) GAAGTT/GAATGA 1 -- us2k12Minor allele frequency- G:0.05MN NA 246
    rs1507041771,2
    		C--128426369(+) TATCTA/GTCTTA 1 -- us2k10--------
    rs8711351,2
    		C,F,A,H--128426393(+) AGAACT/GTCAAA 1 -- us2k118Minor allele frequency- G:0.43NS EA NA WA MN CSA 1190
    rs1842002931,2
    		C--128426433(+) GAGAAC/TGTTTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for POU5F1B (128426535 - 128432311 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for POU5F1B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv499795OTHER Inversion21111241
    nsv7419OTHER Inversion18451855

    Human Gene Mutation Database (HGMD): POU5F1B
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing POU5F1B
    DNA2.0 Custom Variant and Variant Library Synthesis for POU5F1B

    Disorders / Diseases
    for POU5F1B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 1 inferred disease relationship from the University of Copenhagen DISEASES database for POU5F1B:
    Teratoma

    Find genes that share disorders with POU5F1B           About GenesLikeMe

    Genetic Association Database (GAD): POU5F1B
    Human Genome Epidemiology (HuGE) Navigator: POU5F1B (1 document)

    Export disorders for POU5F1B gene to outside databases

    Publications
    for POU5F1B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for POU5F1B gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with POU5F1B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues. (PubMed id 1408763)1, 2, 3 Takeda J.... Bell G.I. (Nucleic Acids Res. 1992)
    2. Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D. (PubMed id 22041458)1, 4 Clark S.L....van den Oord E.J. (Psychol Med 2012)
    3. The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. (PubMed id 18949397)1, 2 Panagopoulos I.... Mertens F. (Oncol. Rep. 2008)
    4. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. (PubMed id 17401366)1, 4 Gudmundsson J....Stefansson K. (Nat. Genet. 2007)
    5. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. (PubMed id 17401363)1, 4 Yeager M....Thomas G. (Nat. Genet. 2007)
    6. Emergence of young human genes after a burst of retroposition in primates. (PubMed id 16201836)1, 2 Marques A.C.... Kaessmann H. (PLoS Biol. 2005)
    7. A diabetic milieu promotes OCT4 and NANOG production in human visceral-derived adipose stem cells. (PubMed id 23064289)1 Dentelli P....Brizzi M.F. (Diabetologia 2013)
    8. Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer. (PubMed id 23933063)1 Wezel F....Southgate J. (Am. J. Pathol. 2013)
    9. Genome-wide association study identifies new prostate cancer susceptibility loci. (PubMed id 21743057)4 Schumacher F.R....Kraft P. (Hum. Mol. Genet. 2011)
    10. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. (PubMed id 20972438)4 Rothman N....Chanock S.J. (Nat. Genet. 2010)

    External Searches for POU5F1B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing POU5F1B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5462 HGNC: 9223 AceView: POU5F1P1 Ensembl:ENSG00000212993 euGenes: HUgn5462
    ECgene: POU5F1B H-InvDB: POU5F1B

    Other Databases showing POU5F1B gene

    (According to HUGE)
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    Specialized Databases showing POU5F1B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for POU5F1B Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for POU5F1B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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