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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POU4F3 Gene

protein-coding   GIFtS: 52
GCID: GC05P145698

POU Class 4 Homeobox 3

(Previous names: POU domain class 4, transcription factor 3)
(Previous symbol: DFNA15)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
POU Class 4 Homeobox 31 2     brain-3C2
BRN3C2 3 5     brn-3C2
DFNA151 2     POU Domain, Class 4, Transcription Factor 32
Brain-Specific Homeobox/POU Domain Protein 3C2 3     Brain-3C3
POU Domain Class 4, Transcription Factor 31     Brn-3C3

External Ids:    HGNC: 92201   Entrez Gene: 54592   Ensembl: ENSG000000910107   OMIM: 6024605   UniProtKB: Q153193   

Export aliases for POU4F3 gene to outside databases

Previous GC identifers: GC05P145687 GC05P146300 GC05P145747 GC05P141099


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for POU4F3 Gene:
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been
observed to play important roles in control of cell identity in several systems. This protein is found in the
retina and may play a role in determining or maintaining the identities of a small subset of visual system
neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
(provided by RefSeq, Mar 2009)

GeneCards Summary for POU4F3 Gene: 
POU4F3 (POU class 4 homeobox 3) is a protein-coding gene. Diseases associated with POU4F3 include deafness, autosomal dominant 15, and deafness, autosomal dominant 28. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO4F3_HUMAN, Q15319
Function: May play a role in determining or maintaining the identities of a small subset of visual system neurons

Gene Wiki entry for POU4F3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_029289.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POU4F3 gene promoter:
         MEF-2A   Egr-2   USF1   Sp1   USF-1   c-Myb   aMEF-2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPOU4F3 promoter sequence
   Search SABiosciences Chromatin IP Primers for POU4F3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU4F3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q32   Ensembl cytogenetic band:  5q32   HGNC cytogenetic band: 5q32

POU4F3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU4F3 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P145698:  view genomic region     (about GC identifiers)

Start:
145,718,587 bp from pter      End:
145,720,083 bp from pter
Size:
1,497 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PO4F3_HUMAN, Q15319 (See protein sequence)
Recommended Name: POU domain, class 4, transcription factor 3  
Size: 338 amino acids; 37052 Da
Subcellular location: Nucleus
Secondary accessions: O60557 Q2M3F8

Explore the universe of human proteins at neXtProt for POU4F3: NX_Q15319

Explore proteomics data for POU4F3 at MOPED 

POU4F3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

POU4F3 Protein Expression

REFSEQ proteins: NP_002691.1  
ENSEMBL proteins: 
 ENSP00000230732  

Human Recombinant Protein Products for POU4F3: 
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Novus Biologicals POU4F3 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for POU4F3 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005730NOT nucleolus IDA--

POU4F3 for ontologies           About GeneDecksing



POU4F3 Antibody Products: 
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Cloud-Clone Corp. CLIAs for POU4F3


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
POU: Homeoboxes / POU class

5/6 InterPro protein domains (see all 6):
 IPR010982 Lambda_DNA-bd_dom
 IPR013847 POU
 IPR000327 POU_specific
 IPR017970 Homeobox_CS
 IPR001356 Homeodomain

Graphical View of Domain Structure for InterPro Entry Q15319

ProtoNet protein and cluster: Q15319

2 Blocks protein domains:
IPB000327 POU domain
IPB013847 POU


UniProtKB/Swiss-Prot: PO4F3_HUMAN, Q15319
Similarity: Belongs to the POU transcription factor family. Class-4 subfamily
Similarity: Contains 1 homeobox DNA-binding domain
Similarity: Contains 1 POU-specific domain


POU4F3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: PO4F3_HUMAN, Q15319
Function: May play a role in determining or maintaining the identities of a small subset of visual system neurons

     Genatlas biochemistry entry for POU4F3:
POU domain,class 4,transcription factor 3,expressed in fetal cochlea

     Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IEA--
     
POU4F3 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for POU4F3:
 Synthetic lethal with Ras 

     10 MGI mutant phenotypes (inferred from 6 alleles(MGI details for Pou4f3):
 behavior/neurological  cellular  growth/size  hearing/vestibular/ear  homeostasis/metabolism 
 mortality/aging  nervous system  normal  reproductive system  vision/eye 

POU4F3 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-outs for POU4F3: Pou4f3tm1Rsd Pou4f3tm1Xia

   inGenious Targeting Laboratory - Custom generated mouse model solutions for POU4F3 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for POU4F3

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miRNA
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Gene Editing
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU4F3


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POU4F3

1 Interacting protein for POU4F3 (Q153193) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
POU3F4P493353I2D: score=2 
About this table

Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006355regulation of transcription, DNA-dependent ----
GO:0006357regulation of transcription from RNA polymerase II promoter IEA--
GO:0007601visual perception TAS7623109
GO:0007605sensory perception of sound IEA--
GO:0021562vestibulocochlear nerve development IEA--

POU4F3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for POU4F3 (PO4F3)

Search CenterWatch for drugs/clinical trials and news about POU4F3 / PO4F3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for POU4F3 gene: 
NM_002700.2  

Unigene Cluster for POU4F3:

POU class 4 homeobox 3
Hs.553499
Unigene Representative Sequence: NM_002700
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000230732(uc003loa.2)
miRNA
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Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
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Clone
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OriGene ORF clones in mouse, rat for POU4F3
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                     Customized lentivirus expression plasmids for stable overexpression of POU4F3 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for POU4F3
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POU4F3
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU4F3

Additional mRNA sequence: 

BC104923.1 BC112207.1 

1 DOTS entry:

DT.100749893 

1 AceView cDNA sequence:

NM_002700 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

POU4F3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATCGCTCTCA
POU4F3 Expression
About this image


See POU4F3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POU4F3

SOURCE GeneReport for Unigene cluster: Hs.553499

UniProtKB/Swiss-Prot: PO4F3_HUMAN, Q15319
Tissue specificity: Brain. Seems to be specific to the retina

    SABiosciences Custom PCR Arrays for POU4F3
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU4F3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU4F3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for POU4F3 gene from 6/13 species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Pou4f31 , 5 POU domain, class 4, transcription factor 31, 5 91.52(n)1
99.11(a)1
  18 (22.58 cM)5
189981  NM_138945.21  NP_620395.21 
 423945395 
chicken
(Gallus gallus)
Aves POU4F31 POU class 4 homeobox 3 72.67(n)
73.27(a)
  395521  NM_204759.1  NP_990090.1 
tropical clawed frog
(Xenopus tropicalis)
Amphibia Str.128262 Transcribed sequence with weak similarity to protein more 73.88(n)    BX717483.1 
zebrafish
(Danio rerio)
Actinopterygii pou4f31 POU domain, class 4, transcription factor 3 77.85(n)
85.98(a)
  30534  NM_131278.1  NP_571353.1 
fruit fly
(Drosophila melanogaster)
Insecta acj63 synaptic target recognition RNA
polymerase II more
47(a)     --
worm
(Caenorhabditis elegans)
Secernentea unc-861 , 3 Pou homeodomain3
Protein UNC-861
65(a)3
49.05(n)1
49.37(a)1
  III(8284820-8288362)3
1761571  NM_001026020.31  NP_001021191.11 


ENSEMBL Gene Tree for POU4F3 (if available)
TreeFam Gene Tree for POU4F3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for POU4F3 gene
POU5F22  POU6F22  POU4F22  POU2F32  POU3F12  POU3F42  POU1F12  POU3F32  
POU3F22  POU2F22  POU5F1B2  POU4F12  POU2F12  POU6F12  POU5F12  
18 SIMAP similar genes for POU4F3 using alignment to 2 protein entries:     PO4F3_HUMAN (see all proteins):
RBM27    FAM3A    FANCA    CNOT2    POU4F2    C12orf23
POU6F1    POU4F1    POU5F1P4    POU3F1    POU3F2    RBM26
POU3F4    POU1F1    POU2F1    POU2F3    POU2F2    POU3F3

POU4F3 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/113 SNPs in POU4F3 are shown (see all 113)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 5 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0456834
Deafness, autosomal dominant, 15 (DFNA15)4--see VAR_0456832 L F mis40--------
VAR_0456824
Deafness, autosomal dominant, 15 (DFNA15)4--see VAR_0456822 L P mis40--------
rs68645301,2
A--140864805(+) CGGAgC/Tgtgtg 1 -- us2k10--------
rs604493181,2
C--145717820(+) TGGGC-/CAAGTT 1 -- us2k10--------
rs1868049491,2
--145992666(+) CCAGTA/GCATTC 1 -- us2k10--------
rs1144006151,2
C,F--145992726(+) GGACAC/TCGCAG 1 -- us2k11Minor allele frequency- T:0.01NA 120
rs1138687811,2
C--145992967(+) CAGAGG/TGCTTT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs1118402001,2
C--145992986(+) GGTTGC/TGCTTG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs1143296411,2
F--145993180(+) AGATTC/TTGGGA 1 -- us2k11Minor allele frequency- T:0.03WA 118
rs37564991,2
C,F,H--145993229(+) GTGAGG/CTCTCT 1 -- us2k12Minor allele frequency- C:0.07NS NA 238

HapMap Linkage Disequilibrium report for POU4F3 (145718587 - 145720083 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for POU4F3: --

Human Gene Mutation Database (HGMD): POU4F3

Locus Specific Mutation Databases (LSDB): POU4F3
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing POU4F3
DNA2.0 Custom Variant and Variant Library Synthesis for POU4F3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 602460   
OMIM disorders: 602459  
UniProtKB/Swiss-Prot: PO4F3_HUMAN, Q15319
  • Deafness, autosomal dominant, 15 (DFNA15) [MIM:602459]: A form of non-syndromic hearing loss with
    variable phenotype in terms of age at onset, levels of progression, and shape of audiograms. Note=The disease is
    caused by mutations affecting the gene represented in this entry

  • 12 diseases for POU4F3:    About MalaCards
    deafness, autosomal dominant 15    deafness, autosomal dominant 28    dfna15 nonsyndromic hearing loss and deafness    merkel cell carcinoma
    sensorineural hearing loss    nonsyndromic hearing loss and deafness, autosomal dominant    nonsyndromic deafness    herpes simplex
    neuronitis    retinitis    prostate cancer    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for POU4F3:
    Sensorineural hearing loss     Nonsyndromic deafness

    POU4F3 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for POU4F3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    dfna15 97.2 9 18228599 (4), 14585957 (2)

    Genetic Association Database (GAD): POU4F3

    Export disorders for POU4F3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for POU4F3 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with POU4F3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans. (PubMed id 9506947)1, 2, 3 Vahava O.... Avraham K.B. (1998)
    2. Missense mutations in POU4F3 cause autosomal dominant hearing impairment DFNA15 and affect subcellular localization and DNA binding. (PubMed id 18228599)1, 2, 9 Collin R.W....Kremer H. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons. (PubMed id 7623109)1, 2 Xiang M.... Nathans J. (1995)
    5. The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity. (PubMed id 14585957)1, 9 Weiss S....Avraham K.B. (2003)
    6. Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma. (PubMed id 12209986)1, 9 Leonard J.H....Sturm R.A. (2002)
    7. A novel frameshift mutation of POU4F3 gene associated with autosomal dominant non-syndromic hearing loss. (PubMed id 20434433)1 Lee H.K....Kim U.K. (2010)
    8. Vestibular impairment in a Dutch DFNA15 family with a n L289F mutation in POU4F3. (PubMed id 19372648)1 van Drunen F.J....Cremers C.W. (2009)
    9. Mild and variable audiometric and vestibular features in a third DFNA15 family with a novel mutation in POU4F3. (PubMed id 19462854)1 de Heer A.M....Cremers C.W. (2009)
    10. Audiometric characteristics of a Dutch family linked to DFNA15 with a novel mutation (p.L289F) in POU4F3. (PubMed id 18347256)1 Pauw R.J....Cremers C.W. (2008)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5459 HGNC: 9220 AceView: POU4F3 Ensembl:ENSG00000091010 euGenes: HUgn5459
    ECgene: POU4F3 H-InvDB: POU4F3

    (According to HUGE)
    About This Section
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for POU4F3 Pharmacogenomics, SNPs, Pathways
    Hereditary hearing loss homepagehttp://webhost.ua.ac.be/hhh/

    (Patent information from GeneIP,
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    Patent Information for POU4F3 gene:
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