Aliases for POU4F2 Gene
Aliases for POU4F2 Gene
External Ids for POU4F2 Gene
- HGNC: 9219
- Entrez Gene: 5458
- Ensembl: ENSG00000151615
- OMIM: 113725
- UniProtKB: Q12837
Previous HGNC Symbols for POU4F2 Gene
- BRN3B
Previous GeneCards Identifiers for POU4F2 Gene
- GC04P148362
- GC04P147935
- GC04P148137
- GC04P147917
- GC04P147779
- GC04P147560
- GC04P143287
Summaries for POU4F2 Gene
-
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]
GeneCards Summary for POU4F2 Gene
POU4F2 (POU Class 4 Homeobox 2) is a Protein Coding gene. Diseases associated with POU4F2 include Breast Cancer. Among its related pathways are Gene Expression and Regulation of TP53 Activity. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is POU4F1.
UniProtKB/Swiss-Prot for POU4F2 Gene
-
DNA-binding transcriptional regulator and coregulator that recognizes and binds to the consensus octamer binding site 5-AT[A/T]A[T/A]T[A/T]A-3 in promoter of target genes (PubMed:19266028, PubMed:23805044). Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor ISL1 to achieve RGC fate specification in the developing retina. Plays also a role in RGC axon formation and guidance by regulating gene expression of specific target genes. Plays a role in TNFSF11-mediated terminal osteoclast differentiation. Binds chromatin at promoter region of target genes (By similarity).
-
Isoform 1: Acts either as a transcriptional activator or repressor (PubMed:19266028, PubMed:23805044). Negatively regulates transcriptional activity of homeobox domain transcriptional factors DLX1 and DLX2, and hence prevents DLX1- and DLX2-mediated ability to promote amacrine cells specification. Involved in the positive regulation of the transcriptional factor PAX6 expression through its binding to the neuroretina-specific enhancer in neuroretina cells. Mediates positive transcriptional regulation of heat shock protein HSPB1 expression in cardiac myocytes. Positively regulates POU4F1 expression by interacting directly with a highly conserved autoregulatory domain surrounding the transcription initiation site of the POU4F1 gene promoter. Plays a role in the regulation of breast cancer cell growth by promoting transcription activation as well as repression of specific target genes. Involved in tumor breast progression and invasion (By similarity). Stimulates the promoter activity of the GTP-binding protein RIT2 gene containing the octamer binding site in retinal ganglion cells (PubMed:23805044). Plays also a role either as a transcriptional coactivator or corepressor. Transcriptional coactivator cooperating with transcription factors ISL1 and ISL2 to potentiate transcriptional activation of retinal ganglion cell (RGC) target genes. Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to the octamer motif. Binds to the octamer binding site to form a ternary complex with ISL1 in promoter of target genes (By similarity).
-
Isoform 2: Acts either as a transcriptional activator or repressor (PubMed:23805044). Stimulates the promoter activity of the neuronal nicotinic acetylcholine receptor alpha CHRNA2. Negatively regulates the apoptosis regulator BAX promoter activity. Inhibits promoter activity of the neuronal intermediate filament protein alpha-internexin INA gene. Plays a role in the regulation of breast cancer cell growth by promoting transcription activation as well as repression of specific target genes. Involved in tumor breast progression and invasion (By similarity). Inhibits the promoter activity of the GTP-binding protein RIT2 gene containing the octamer binding site in retinal ganglion cells (PubMed:23805044). Plays also a role either as transcriptional coactivator or corepressor. Transcriptional coactivator cooperating with transcription factors TP53 to potentiate transcriptional activation of BAX promoter activity, and hence increases neuronal cell apoptosis. Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to the octamer motif. Acts also as a transcriptional coactivator via its interaction with the transcription factor ESR1 (By similarity).
Additional gene information for POU4F2 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POU4F2 Gene
Genomics for POU4F2 Gene
GeneHancer (GH) Regulatory Elements for POU4F2 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH04I146638 | Promoter | 0.9 | EPDnew | 550.8 | 0.0 | -19 | 0.1 | MAZ SP3 ZFP37 SIN3A ZNF335 ZNF341 CTBP2 ZBTB26 EZH2 | POU4F2 RNU1-44P | |
GH04I146333 | Enhancer | 0.9 | Ensembl ENCODE | 10.1 | -305.0 | -305003 | 1 | HDGF PKNOX1 FOXA2 ZBTB6 BATF IRF4 ZSCAN5C PRDM10 ETV6 IKZF2 | ENSG00000251010 POU4F2 LOC105377472 GC04P146380 SLC10A7 | |
GH04I146328 | Enhancer | 0.9 | FANTOM5 Ensembl ENCODE | 9.8 | -309.2 | -309191 | 3 | JUND POLR2A JUN FOS EP300 | ENSG00000251010 POU4F2 LOC105377472 GC04P146380 SLC10A7 | |
GH04I146269 | Enhancer | 0.7 | FANTOM5 | 9.3 | -369.4 | -369384 | 0.2 | ATF7 BCLAF1 IKZF2 RUNX3 SRF ZNF687 ZBED1 NR2F1 TRIM22 DPF2 | ENSG00000251010 REELD1 POU4F2 ZNF827 LSM6 LOC105377472 SLC10A7 | |
GH04I146974 | Enhancer | 0.6 | ENCODE | 9.9 | +336.4 | 336357 | 0.9 | TEAD4 TAL1 CEBPB CBFA2T3 ZBTB8A OSR2 PRDM6 GATA3 ZNF610 POLR2A | TTC29 POU4F2 GC04M146965 ENSG00000248346 ENSG00000260090 LOC105377473 |
- Top Transcription factor binding sites by QIAGEN in the POU4F2 gene promoter:
Regulatory Element Products
Genomic Locations for POU4F2 Gene
- chr4:146,638,893-146,642,474
- (GRCh38/hg38)
- Size:
- 3,582 bases
- Orientation:
- Plus strand
- chr4:147,560,045-147,563,626
- (GRCh37/hg19)
Genomic View for POU4F2 Gene
- Cytogenetic band:
-
- 4q31.22 by Ensembl
- 4q31.22 by Entrez Gene
- 4q31.22 by HGNC


RefSeq DNA sequence for POU4F2 Gene
Proteins for POU4F2 Gene
-
Protein details for POU4F2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q12837-PO4F2_HUMAN
- Recommended name:
- POU domain, class 4, transcription factor 2
- Protein Accession:
- Q12837
- B1PJR6
- B2RC84
- Q13883
- Q14987
Protein attributes for POU4F2 Gene
- Size:
- 409 amino acids
- Molecular mass:
- 43087 Da
- Quaternary structure:
-
- Isoform 1: Interacts with DLX1 (via homeobox DNA-binding domain); this interaction suppresses DLX1-mediated transcriptional activity in postnatal retina and enhances retinal ganglion cell (RGC) differentiation. Isoform 1: Interacts with DLX2 (via homeobox DNA-binding domain); this interaction enhances RGC differentiation. Isoform 1: Interacts (via C-terminus) with ISL1 (via C-terminus). Isoform 1: Interacts with ISL2. Isoform 1 interacts with LHX2. Isoform 2: Interacts (via C-terminus) with TP53 (via C-terminus). Isoform 2: Interacts with POU4F1 isoform 1; this interaction inhibits both POU4F1 DNA-binding and transcriptional activities. Isoform 2: Interacts (C-terminus) with ESR1 (via DNA-binding domain); this interaction increases the estrogen receptor ESR1 transcriptional activity in a DNA- and ligand 17-beta-estradiol-independent manner.
Protein Expression for POU4F2 Gene
Post-translational modifications for POU4F2 Gene
Other Protein References for POU4F2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Abcam antibodies for POU4F2
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-
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Assay Products
No data available for DME Specific Peptides for POU4F2 Gene
Domains & Families for POU4F2 Gene
Gene Families for POU4F2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for POU4F2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for POU4F2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q12837UniProtKB/Swiss-Prot:
PO4F2_HUMAN :- The transcriptional activation domain within the N-terminal region is sufficient to induce transcriptional activity. The transcriptional repression domain containing the POU-specific domain and POU homeodomain is necessary for DNA-binding activity and also sufficient to induce transcriptional repression in a DNA-binding independent manner (By similarity). The polyhistidine repeat acts as a targeting signal to nuclear speckles (PubMed:19266028).
- Belongs to the POU transcription factor family. Class-4 subfamily.
- Domain:
-
- The transcriptional activation domain within the N-terminal region is sufficient to induce transcriptional activity. The transcriptional repression domain containing the POU-specific domain and POU homeodomain is necessary for DNA-binding activity and also sufficient to induce transcriptional repression in a DNA-binding independent manner (By similarity). The polyhistidine repeat acts as a targeting signal to nuclear speckles (PubMed:19266028).
- Family:
-
- Belongs to the POU transcription factor family. Class-4 subfamily.
Function for POU4F2 Gene
Molecular function for POU4F2 Gene
- GENATLAS Biochemistry:
- POU domain,class 4,transcription factor 2,expressed in a subset of retinal ganglion cells
- UniProtKB/Swiss-Prot Function:
- DNA-binding transcriptional regulator and coregulator that recognizes and binds to the consensus octamer binding site 5-AT[A/T]A[T/A]T[A/T]A-3 in promoter of target genes (PubMed:19266028, PubMed:23805044). Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor ISL1 to achieve RGC fate specification in the developing retina. Plays also a role in RGC axon formation and guidance by regulating gene expression of specific target genes. Plays a role in TNFSF11-mediated terminal osteoclast differentiation. Binds chromatin at promoter region of target genes (By similarity).
- UniProtKB/Swiss-Prot Function:
- Isoform 1: Acts either as a transcriptional activator or repressor (PubMed:19266028, PubMed:23805044). Negatively regulates transcriptional activity of homeobox domain transcriptional factors DLX1 and DLX2, and hence prevents DLX1- and DLX2-mediated ability to promote amacrine cells specification. Involved in the positive regulation of the transcriptional factor PAX6 expression through its binding to the neuroretina-specific enhancer in neuroretina cells. Mediates positive transcriptional regulation of heat shock protein HSPB1 expression in cardiac myocytes. Positively regulates POU4F1 expression by interacting directly with a highly conserved autoregulatory domain surrounding the transcription initiation site of the POU4F1 gene promoter. Plays a role in the regulation of breast cancer cell growth by promoting transcription activation as well as repression of specific target genes. Involved in tumor breast progression and invasion (By similarity). Stimulates the promoter activity of the GTP-binding protein RIT2 gene containing the octamer binding site in retinal ganglion cells (PubMed:23805044). Plays also a role either as a transcriptional coactivator or corepressor. Transcriptional coactivator cooperating with transcription factors ISL1 and ISL2 to potentiate transcriptional activation of retinal ganglion cell (RGC) target genes. Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to the octamer motif. Binds to the octamer binding site to form a ternary complex with ISL1 in promoter of target genes (By similarity).
- UniProtKB/Swiss-Prot Function:
- Isoform 2: Acts either as a transcriptional activator or repressor (PubMed:23805044). Stimulates the promoter activity of the neuronal nicotinic acetylcholine receptor alpha CHRNA2. Negatively regulates the apoptosis regulator BAX promoter activity. Inhibits promoter activity of the neuronal intermediate filament protein alpha-internexin INA gene. Plays a role in the regulation of breast cancer cell growth by promoting transcription activation as well as repression of specific target genes. Involved in tumor breast progression and invasion (By similarity). Inhibits the promoter activity of the GTP-binding protein RIT2 gene containing the octamer binding site in retinal ganglion cells (PubMed:23805044). Plays also a role either as transcriptional coactivator or corepressor. Transcriptional coactivator cooperating with transcription factors TP53 to potentiate transcriptional activation of BAX promoter activity, and hence increases neuronal cell apoptosis. Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to the octamer motif. Acts also as a transcriptional coactivator via its interaction with the transcription factor ESR1 (By similarity).
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 17637757 |
GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | IDA | 23805044 |
GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IEA,IDA | 17637757 |
GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | ISS,IEA | -- |
GO:0003677 | DNA binding | IEA | -- |
Phenotypes for POU4F2 Gene
- MGI mutant phenotypes for POU4F2:
- inferred from 11 alleles
- GenomeRNAi human phenotypes for POU4F2:
Animal Models for POU4F2 Gene
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miRNA for POU4F2 Gene
- miRTarBase miRNAs that target POU4F2
miRNA Products
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Inhibitory RNA Products
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for POU4F2 Gene
Localization for POU4F2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for POU4F2 Gene
- Nucleus. Nucleus speckle. Cytoplasm. Cell membrane.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | ISS | -- |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0005737 | cytoplasm | ISS | -- |
GO:0005886 | plasma membrane | IEA | -- |
GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for POU4F2 Gene
Pathways & Interactions for POU4F2 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Regulation of TP53 Activity | ||
2 | Gene Expression |
.48
|
|
3 | Direct p53 effectors |
Pathways by source for POU4F2 Gene
1 BioSystems pathway for POU4F2 Gene
Interacting Proteins for POU4F2 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | ISS | -- |
GO:0000165 | MAPK cascade | IDA | 21241485 |
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0006366 | transcription by RNA polymerase II | IEA | -- |
No data available for SIGNOR curated interactions for POU4F2 Gene
Transcripts for POU4F2 Gene
mRNA/cDNA for POU4F2 Gene
- (1) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (7) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for POU4F2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for POU4F2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Immature Ganglion Cells Ganglion Cell Layer
- Mature Ganglion Cells Ganglion Cell Layer
- Ganglion Precursor Cells Ganglion Cell Layer
- Retinal cells(Eiraku M et. al. 2012)
-
Neurons
- Immature Ganglion Cells Ganglion Cell Layer
- Mature Ganglion Cells Ganglion Cell Layer
- Ganglion Precursor Cells Ganglion Cell Layer
- Neural Tube (Nervous System)
- NULL (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for POU4F2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for POU4F2 Gene
NURSA nuclear receptor signaling pathways regulating expression of POU4F2 Gene:
POU4F2SOURCE GeneReport for Unigene cluster for POU4F2 Gene:
Hs.266mRNA Expression by UniProt/SwissProt for POU4F2 Gene:
Q12837-PO4F2_HUMANEvidence on tissue expression from TISSUES for POU4F2 Gene
- Eye(4.5)
Primer Products
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OriGene qPCR primer pairs for POU4F2
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No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for POU4F2 Gene
Orthologs for POU4F2 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | POU4F2 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | POU4F2 34 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | POU4F2 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | POU4F2 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Pou4f2 33 |
|
||
mouse (Mus musculus) |
Mammalia | Pou4f2 33 16 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | POU4F2 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | BRN3 34 |
|
OneToMany | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | pou4f2 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | pou4f2 33 34 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | acj6 35 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | unc-86 35 34 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for POU4F2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for POU4F2 Gene
Paralogs for POU4F2 Gene
(6) SIMAP similar genes for POU4F2 Gene using alignment to 1 proteins:
Variants for POU4F2 Gene
SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000148561 | -- | 146,637,218(+) | G/A | upstream_transcript_variant | |
rs1000249553 | -- | 146,641,278(+) | T/C | 3_prime_UTR_variant | |
rs1000567213 | -- | 146,637,645(+) | G/A | upstream_transcript_variant | |
rs1000821601 | -- | 146,639,666(+) | C/T | intron_variant | |
rs1000985954 | -- | 146,642,673(+) | G/A | downstream_transcript_variant |
Additional Variant Information for POU4F2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- POU4F2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POU4F2 Gene
Disorders for POU4F2 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
breast cancer |
|
Additional Disease Information for POU4F2
No data available for UniProtKB/Swiss-Prot and Genatlas for POU4F2 Gene
Publications for POU4F2 Gene
- The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells. (PMID: 11526481) Dennis JH … Latchman DS (Oncogene 2001) 3 4 22 58
- Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells. (PMID: 7691107) Xiang M … Nathans J (Neuron 1993) 3 4 22 58
- The human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domain. (PMID: 8332509) Ring CJ … Latchman DS (Nucleic acids research 1993) 2 3 4 58
- RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. (PMID: 23805044) Zhang L … Esumi N (Molecular vision 2013) 3 4 58
- Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment. (PMID: 19266028) Salichs E … de la Luna S (PLoS genetics 2009) 3 4 58
Products for POU4F2 Gene
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- GenScript: Next-day shipping of latest version cDNA ORF clones for POU4F2 in any vector
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- GenScript: Design CRISPR guide RNA sequences for POU4F2
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- Vector-based siRNA and miRNA, Ready for Transfection
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- Sino Biological Human cDNA Clone for POU4F2
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- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for POU4F2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for POU4F2
- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
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- Browse Antibodies at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for POU4F2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for POU4F2
- VectorBuilder custom plasmid, inducible vectors for POU4F2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for POU4F2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 36 available POU4F2 Antibodies ranked by validation data
- Compare Top POU4F2 Antibodies
- antibodies-online: Search results for available POU4F2 related products ranked by validation data
- antibodies-online: Search results for 3 available POU4F2 Proteins ranked by validation data
- Compare Top POU4F2 Proteins
- Search GeneTex for Antibodies for POU4F2
- Search GeneTex for Proteins for POU4F2
- ViGene Biosciences adenoviral particle packaged cDNA for POU4F2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for POU4F2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for POU4F2 gene
- Search ViGene Biosciences for POU4F2
- Santa Cruz Biotechnology (SCBT) Antibodies for POU4F2
- Search Santa Cruz Biotechnology (SCBT) for POU4F2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for POU4F2
- Horizon Cell Lines for POU4F2
- genomics-online: cdna clones - Search results for 73 available POU4F2 gene related products
- Overview of 73 available POU4F2 gene related products
- orf clones - Search results for 73 available POU4F2 gene related products
- Overview of 73 available POU4F2 gene related products
- genomics-online: gRNA clones - Search results for 73 available POU4F2 gene related products
- Overview of 73 available POU4F2 gene related products
- genomics-online: primer clones - Search results for 73 available POU4F2 gene related products
- Overview of 73 available POU4F2 gene related products
- genomics-online: shRNA clones - Search results for 73 available POU4F2 gene related products
- Overview of 73 available POU4F2 gene related products
Sources for POU4F2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew