Aliases for POU4F2 Gene
External Ids for POU4F2 Gene
Previous HGNC Symbols for POU4F2 Gene
Previous GeneCards Identifiers for POU4F2 Gene
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]
GeneCards Summary for POU4F2 Gene
POU4F2 (POU Class 4 Homeobox 2) is a Protein Coding gene. Diseases associated with POU4F2 include Differentiating Neuroblastoma and Wilms Tumor Susceptibility-5. Among its related pathways are Regulation of TP53 Activity and Gene Expression. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is POU4F1.
UniProtKB/Swiss-Prot for POU4F2 Gene
Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons.