Aliases for POU4F2 Gene
External Ids for POU4F2 Gene
Previous HGNC Symbols for POU4F2 Gene
Previous GeneCards Identifiers for POU4F2 Gene
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]
GeneCards Summary for POU4F2 Gene
POU4F2 (POU Class 4 Homeobox 2) is a Protein Coding gene. Diseases associated with POU4F2 include Differentiating Neuroblastoma and Borderline Glaucoma. Among its related pathways are Regulation of TP53 Activity and Gene Expression. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is POU4F1.
UniProtKB/Swiss-Prot for POU4F2 Gene
Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons.