Aliases for POU4F1 Gene
External Ids for POU4F1 Gene
Previous HGNC Symbols for POU4F1 Gene
Previous GeneCards Identifiers for POU4F1 Gene
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012]
GeneCards Summary for POU4F1 Gene
POU4F1 (POU Class 4 Homeobox 1) is a Protein Coding gene. Diseases associated with POU4F1 include Cervical Cancer, Somatic and Borderline Glaucoma. Among its related pathways are Regulation of TP53 Activity and Gene Expression. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is POU4F2.
UniProtKB/Swiss-Prot for POU4F1 Gene
Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.