Aliases for POU3F3 Gene
External Ids for POU3F3 Gene
Previous GeneCards Identifiers for POU3F3 Gene
This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]
GeneCards Summary for POU3F3 Gene
POU3F3 (POU Class 3 Homeobox 3) is a Protein Coding gene. Diseases associated with POU3F3 include Central Nervous System Tuberculosis and Agraphia. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and HMG box domain binding. An important paralog of this gene is POU3F2.
UniProtKB/Swiss-Prot for POU3F3 Gene
Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5-ATTTGCAT-3) (By similarity).