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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POU3F3 Gene

protein-coding   GIFtS: 52
GCID: GC02P105471

POU class 3 homeobox 3

(Previous names: POU domain class 3, transcription factor 3 )
 Explore 2 diseases affiliated with
POU3F3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for POU3F3    

Aliases
for POU3F3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
POU Class 3 Homeobox 31 2     Brain-13
BRN11 2 3     Brn-13
OTF81 2 3     Oct-83
Brain-Specific Homeobox/POU Domain Protein 12 3     POU Domain, Class 3, Transcription Factor 32
Octamer-Binding Protein 82 3     Brain-13
Octamer-Binding Transcription Factor 82 3     Brn-13
OTF-82 3     Oct-83
POU Domain Class 3, Transcription Factor 31     

External Ids:    HGNC: 92161   Entrez Gene: 54552   Ensembl: ENSG000001989147   OMIM: 6024805   UniProtKB: P202643   

Export aliases for POU3F3 gene to outside databases

Previous GC identifers: GC02P103336 GC02P103924 GC02P105076 GC02P105093 GC02P104930 GC02P099242


Summaries
for POU3F3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for POU3F3:
POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are expressed in
the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA
sequences (summarized by Sumiyama et al., 1996 (PubMed 8703082)).(supplied by OMIM, Jul 2010)

UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
Function: Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is
implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the
octamer motif (5'-ATTTGCAT-3') (By similarity)




Genomic Views
for POU3F3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022171.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POU3F3 gene promoter:
         GR   FOXF2   Pax-5   Bach2   CUTL1   N-Myc   PPAR-gamma1   Chx10   PPAR-gamma2   GR-alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for POU3F3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU3F3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12.1   Ensembl cytogenetic band:  2q12.1   HGNC cytogenetic band: 2q12.1

POU3F3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU3F3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P105471:  view genomic region     (about GC identifiers)

Start:
 105,471,969 bp from pter      End:
 105,476,929 bp from pter
Size:
 4,961 bases      Orientation:
 plus strand

Proteins
for POU3F3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264 (See protein sequence)
Recommended Name: POU domain, class 3, transcription factor 3  
Size: 500 amino acids; 50327 Da
Subcellular location: Nucleus
Secondary accessions: P78379 Q4ZG25

Explore the universe of human proteins at neXtProt for POU3F3: NX_P20264

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P20264

    • POU3F3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006227.1  
    ENSEMBL proteins: 
     ENSP00000355001  

    Human Recombinant Protein Products: 
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    Browse Proteins at Uscn

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--


    POU3F3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for POU3F3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    POU3F3 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR010982 Lambda_DNA-bd_dom
     IPR016362 Transcription_factor_POU
     IPR013847 POU
     IPR000327 POU_specific
     IPR017970 Homeobox_CS

    Graphical View of Domain Structure for InterPro Entry P20264

    ProtoNet protein and cluster: P20264

    2 Blocks protein families:
    IPB000327 POU domain
    IPB013847 POU


    UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
    Similarity: Belongs to the POU transcription factor family. Class-3 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 POU-specific domain


    Function
    for POU3F3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
    Function: Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is
    implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the
    octamer motif (5'-ATTTGCAT-3') (By similarity)

         Genatlas biochemistry entry for POU3F3:
    POU domain,class 3,transcription factor 3,expressed in brain

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: POU3F3
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity ----
    GO:0005515protein binding ----
    GO:0016563transcription activator activity ----


    POU3F3 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for POU3F3:
     Decreased Wnt reporter activit  Decreased number of cells in m 

    Animal Models:
         Mouse knock-outs for POU3F3: Pou3f3tm1Rmc Pou3f3tm1Tno
         8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Pou3f3):
     cellular  craniofacial  hearing/vestibular/ear  homeostasis/metabolism  mortality/aging 
     nervous system  renal/urinary system  skeleton 

    POU3F3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for POU3F3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Transcription factors in neurogenesis
    		Transcription factors in neurogenesis1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for POU3F3
        Transcription factors in neurogenesis




    POU3F3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POU3F3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/13 Interacting proteins for POU3F3 (P202642, 3 ENSP000003550014) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1R15AO758072, 3, ENSP000002004534MINT-63546 I2D: score=4 STRING: ENSP00000200453
    CAV1Q031353, ENSP000003391914I2D: score=1 STRING: ENSP00000339191
    SOX11P357163, ENSP000003225684I2D: score=1 STRING: ENSP00000322568
    SOX10P566933, ENSP000003541304I2D: score=1 STRING: ENSP00000354130
    POU3F4P493353, ENSP000003622964I2D: score=3 STRING: ENSP00000362296
    About this table

    Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ----
    GO:0001822kidney development ----
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0007417central nervous system development TAS8703082


    POU3F3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for POU3F3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for POU3F3
    Search CenterWatch for drugs/clinical trials and news about POU3F3 / PO3F3 

    Transcripts
    for POU3F3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for POU3F3 gene: 
    NM_006236.1  

    Unigene Cluster for POU3F3:

    POU class 3 homeobox 3
    Hs.673855  [show with all ESTs]
    Unigene Representative Sequence: NM_006236
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000361360(uc010ywg.2)

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    Inhib. RNA
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    OriGene shRNA RFP: POU3F3
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    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POU3F3

    1 DOTS entry:

    DT.95081172 

    10 AceView cDNA sequences:

    NM_006236 F11569 BI464570 BF341357 BF355891 BF511732 AI796236 BX418484 
    BG911951 AF067777 

    GeneLoc Exon Structure


    Expression
    for POU3F3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    POU3F3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACGCCGCCCG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    POU3F3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/22 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 22) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyLoop of HenleLoop of Henle CellsKidney
    KidneyRenal VesicleDistal Renal Vesicle CellsKidney
    KidneyS-shaped Body Distal SegmentS-shaped Body Distal CellsKidney
    KidneyS-shaped Body Medial SegmentS-shaped Body Medial CellsKidney
    KidneyDistal TubuleDistal Tubule CellsKidney
    KidneyProximal TubuleProximal Tubule CellsKidney
    KidneyRenal Collecting Duct SystemCollecting Duct CellsKidney
    BoneMaxillary ProcessBone
    BrainHypothalamusBrain
    BrainMedulla OblongataBrain
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See POU3F3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for POU3F3

    SOURCE GeneReport for Unigene cluster: Hs.673855

    UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
    Tissue specificity: Brain

        SABiosciences Expression via Pathway-Focused PCR Arrays including POU3F3: 
              Neurogenesis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for POU3F3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for POU3F3 gene from 17 species (see representative species )    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Pou3f31 , 5 POU domain, class 3, transcription factor 31, 5 91.68(n)1
    99.6(a)1    		   1 (21.21 cM)5
    189931  NM_008900.21  NP_032926.21 
     426957685 
    rat
    (Rattus norvegicus)    		 Mammalia Pou3f31 POU class 3 homeobox 3 91.68(n)
    99.4(a)    		   192109  NM_138837.1  NP_620192.1 
    oppossum
    (Monodelphis domestica)    		 Mammalia POU3F36
    		 Uncharacterized protein
    		 95(a)
    		 1 ↔ 1
    		 7(69156684-69177355)
    chicken
    (Gallus gallus)    		 Aves LOC1008574221 POU domain, class 3, transcription factor 4-like 89.54(n)
    91.67(a)    		   100857422  XM_003641077.1  XP_003641125.1 
    lizard
    (Anolis carolinensis)    		 Reptilia O73627_ANOCA6
    		 Brain-1 gene
    		 74(a)
    		 1 ↔ 1
    		 GL343243.1(157682-159046)
    zebrafish
    (Danio rerio)    		 Actinopterygii Y07906.12   -- 76.06(n)   30386  Y07906.1 
    sea urchin
    (Strongylocentrotus purpuratus)    		 Echinoidea --
    		 --
    		 36(a)
    		 possible ortholog
    		 scaffold_554(60127-61530)
    fruit fly
    (Drosophila melanogaster)    		 Insecta vvl1 , 3 peripheral nervous system development DNA
    binding3
    ventral veins lacking1    		 81(a)
    (best of 3)3
    64.29(n)1
    64.29(a)1    		   3 65C53
    387521  NM_001169884.11  NP_001163355.11 
    mosquito
    (Anopheles gambiae)    		 Insecta AgaP_AGAP0058781 AGAP005878-PB 65.7(n)
    63.59(a)    		   1276544  XM_315904.4  XP_315904.4 
    honey bee
    (Apis mellifera)    		 Insecta --
    		 --
    		 40(a)
    		 1 → many
    		 Group10.10(99920-101299)
    worm
    (Caenorhabditis elegans)    		 Secernentea ceh-63 Homeobox domain, Pou domain - N-terminal to
    homeobox more    		 69(a)   I(8506480-8510320)   --
    schistosome parasite
    (Schistosoma mansoni)    		 Trematoda Smp_1495706
    		 Pou3/brn-1, putative
    		 16(a)
    		 possible ortholog
    		 Smp_scaff000130(379355-389097)
    common water flea
    (Daphnia pulex)    		 Crustacea --
    		 --
    		 88(a)
    		 1 → many
    		 scaffold_86(434292-434795)
    Trichoplax
    (Trichoplax adhaerens)    		 Tricoplacia --
    		 --
    		 85(a)
    		 possible ortholog
    		 scaffold_5(3998310-3998762)
    sea anemone
    (Nematostella vectensis)    		 Anthozoa --
    --
    (see all 3)    		 --
    		 72(a)
    62(a)
    (see all 3)    		 1 ↔ many
    possible ortholog
    (see all 3)    		 scaffold_262(71949-72503) NEMVEDRAFT_v1g129257
    scaffold_450(6340-6777) NEMVEDRAFT_v1g3734
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes YOX1(YML027W)4 Homeodomain-containing transcriptional repressor, binds more   --   13(221406-222563) 854981  NP_013685.1 
    rice
    (Oryza sativa)    		 Liliopsida AK060806.12   -- 73.23(n)    AK060806.1 
            Species with no ortholog for POU3F3

    ENSEMBL Gene Tree for POU3F3 (if available)
    TreeFam Gene Tree for POU3F3 (if available) 

    Paralogs
    for POU3F3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for POU3F3 gene
    POU5F22  POU6F22  POU4F22  POU2F32  POU3F42  POU3F12  POU1F12  POU4F32  
    POU3F22  POU2F22  POU5F1B2  POU2F12  POU4F12  POU5F12  POU6F12  
    11 SIMAP similar genes for POU3F3 using alignment to 1 protein entry:     PO3F3_HUMAN:
    POU6F1    POU1F1    POU3F2    POU5F1P4    POU3F1    POU3F4
    POU2F1    POU4F3    POU2F3    POU4F1    POU4F2

    POU3F3 for paralogs           About GeneDecksing



    Genomic Variants
    for POU3F3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/29 NCBI SNPs in POU3F3 are shown (see all 29)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs729476611,2
    		C,F,--105470075(+) TCTCTG/AGCGGG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1485060221,2
    		C,--105470243(+) GCGAAA/CGCCCA 1 -- us2k10--------
    rs1819834471,2
    		--105470367(+) AGGACG/TACAGA 1 -- us2k10--------
    rs1145105361,2
    		--105470622(+) GTCAGA/TTCGGA 1 -- us2k11Minor allele frequency- T:0.01NA 120
    rs1995151441,2
    		C--105470676(+) ACTTTC/TCCTCT 1 -- us2k10--------
    rs1418196281,2
    		--105470761(+) CCAGCG/TCCCGC 1 -- us2k10--------
    rs1460611211,2
    		--105471017(+) TTCTGC/TCCAAA 1 -- us2k10--------
    rs1863104321,2
    		--105471184(+) CAGAGC/GGGGAG 1 -- us2k10--------
    rs1907937691,2
    		--105471243(+) CACGCC/TTTCAA 1 -- us2k10--------
    rs1147163981,2
    		--105471270(+) CTACTC/TTAAGG 1 -- us2k11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for POU3F3 (105471969 - 105476929 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for POU3F3: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for POU3F3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    POU3F3 for disorders           About GeneDecksing

    OMIM gene information: 602480    OMIM disorders: --

    2 diseases for POU3F3:    About MalaCards
    cerebritis    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: POU3F3 (1 document)

    Export disorders for POU3F3 gene to outside databases

    Publications
    for POU3F3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for POU3F3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with POU3F3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals. (PubMed id 8703082)1, 2 Sumiyama K.... Ueda S. (1996)
    2. Expression of a large family of POU-domain regulatory genes in mammalian brain development. (PubMed id 2739723)1, 2 He X....Rosenfeld M.G. (1989)
    3. Cooperative function of POU proteins and SOX proteins in glial cells. (PubMed id 9632656)1, 9 Kuhlbrodt K....Wegner M. (1998)
    4. The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. (PubMed id 16582099)1 Wissmuller S....Wegner M. (2006)
    5. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    6. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    7. Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2. (PubMed id 9457692)1 Sumiyama K....Ueda S. (1998)
    8. The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U. (PubMed id 9105675)1 Malik K.F....Young W.S. (1997)
    9. Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region. (PubMed id 15872005)9 Bouchard M....Busslinger M. (2005)
    10. Redundancy of class III POU proteins in the oligodendrocyte lineage. (PubMed id 9405434)9 Schreiber J....Wegner M. (1997)

    External Searches for POU3F3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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    Genome Databases showing POU3F3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5455 HGNC: 9216 AceView: POU3F3 Ensembl:ENSG00000198914 euGenes: HUgn5455
    ECgene: POU3F3 H-InvDB: POU3F3

    Other Databases showing POU3F3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing POU3F3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for POU3F3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for POU3F3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for POU3F3 gene:
    Search GeneIP for patents involving POU3F3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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