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POU3F3 Gene

protein-coding   GIFtS: 50
GCID: GC02P105471

POU Class 3 Homeobox 3

(Previous names: POU domain class 3, transcription factor 3)
  Search for POU3F3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
POU Class 3 Homeobox 31 2     brain-12
Brain-Specific Homeobox/POU Domain Protein 12 3     brn-12
Octamer-Binding Protein 82 3     oct-82
Octamer-Binding Transcription Factor 82 3     POU Domain, Class 3, Transcription Factor 32
BRN12 3     Brain-13
OTF-82 3     Brn-13
OTF82 3     Oct-83
POU Domain Class 3, Transcription Factor 31     

External Ids:    HGNC: 92161   Entrez Gene: 54552   Ensembl: ENSG000001989147   OMIM: 6024805   UniProtKB: P202643   

Export aliases for POU3F3 gene to outside databases

Previous GC identifers: GC02P103336 GC02P103924 GC02P105076 GC02P105093 GC02P104930 GC02P099242


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for POU3F3 Gene:
POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are
expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding
to octamer DNA sequences (summarized by Sumiyama et al., 1996 (PubMed 8703082)).(supplied by OMIM, Jul 2010)

GeneCards Summary for POU3F3 Gene:
POU3F3 (POU class 3 homeobox 3) is a protein-coding gene. GO annotations related to this gene include HMG box domain binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
Function: Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal
development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer
element contains the octamer motif (5'-ATTTGCAT-3') (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the POU3F3 gene promoter:
         GR   FOXF2   Pax-5   Bach2   CUTL1   N-Myc   PPAR-gamma1   Chx10   PPAR-gamma2   GR-alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for POU3F3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU3F3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12.1   Ensembl cytogenetic band:  2q12.1   HGNC cytogenetic band: 2q12.1

POU3F3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU3F3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P105471:  view genomic region     (about GC identifiers)

Start:
105,471,969 bp from pter      End:
105,476,929 bp from pter
Size:
4,961 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264 (See protein sequence)
Recommended Name: POU domain, class 3, transcription factor 3  
Size: 500 amino acids; 50327 Da
Secondary accessions: P78379 Q4ZG25

Explore the universe of human proteins at neXtProt for POU3F3: NX_P20264

Explore proteomics data for POU3F3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See POU3F3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006227.1  
    ENSEMBL proteins: 
     ENSP00000355001  

    POU3F3 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    Search eBioscience for ELISAs for POU3F3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    POU: Homeoboxes / POU class

    Selected InterPro protein domains (see all 7):
     IPR010982 Lambda_DNA-bd_dom
     IPR016362 Transcription_factor_POU
     IPR013847 POU
     IPR000327 POU_specific
     IPR017970 Homeobox_CS

    Graphical View of Domain Structure for InterPro Entry P20264

    ProtoNet protein and cluster: P20264

    2 Blocks protein domains:
    IPB000327 POU domain
    IPB013847 POU


    UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
    Similarity: Belongs to the POU transcription factor family. Class-3 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 POU-specific domain


    Find genes that share domains with POU3F3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PO3F3_HUMAN, P20264
    Function: Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal
    development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer
    element contains the octamer motif (5'-ATTTGCAT-3') (By similarity)

         Genatlas biochemistry entry for POU3F3:
    POU domain,class 3,transcription factor 3,expressed in brain

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
    GO:0043565sequence-specific DNA binding ISS--
    GO:0071837HMG box domain binding IEA--
         
    Find genes that share ontologies with POU3F3           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for POU3F3:
     Decreased Wnt reporter activit  Decreased number of cells in m 

         8 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Pou3f3):
     cellular  craniofacial  hearing/vestibular/ear  homeostasis/metabolism  mortality/aging 
     nervous system  renal/urinary system  skeleton 

    Find genes that share phenotypes with POU3F3           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for POU3F3: Pou3f3tm1Rmc Pou3f3tm1Tno

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POU3F3
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    GenScript: all cDNA clones in your preferred vector: POU3F3 (NM_006236)
    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PO3F3_HUMAN, P20264: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    Find genes that share ontologies with POU3F3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for POU3F3 About    
    See pathways by source

    SuperPathContained pathways About
    1Transcription factors in neurogenesis
    Transcription factors in neurogenesis



        Pathway & Disease-focused RT2 Profiler PCR Arrays including POU3F3: 
              Neurogenesis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for POU3F3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for POU3F3 (P202642, 3 ENSP000003550014) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1R15AO758072, 3, ENSP000002004534MINT-63546 I2D: score=4 STRING: ENSP00000200453
    CAV1Q031353, ENSP000003391914I2D: score=1 STRING: ENSP00000339191
    SOX11P357163, ENSP000003225684I2D: score=1 STRING: ENSP00000322568
    SOX10P566933, ENSP000003541304I2D: score=1 STRING: ENSP00000354130
    POU3F4P493353, ENSP000003622964I2D: score=3 STRING: ENSP00000362296
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001822kidney development ----
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007417central nervous system development TAS8703082
    GO:0008284positive regulation of cell proliferation ISS--

    Find genes that share ontologies with POU3F3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for POU3F3 (PO3F3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for POU3F3 gene: 
    NM_006236.1  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000361360(uc010ywg.2)
    miRNA
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    Inhib. RNA
    Products:
         
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    Predesigned siRNA for gene silencing in human, mouse, rat POU3F3
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    GenScript: all cDNA clones in your preferred vector: POU3F3 (NM_006236)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU3F3
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      QuantiTect SYBR Green Assays in human, mouse, rat POU3F3
      QuantiFast Probe-based Assays in human, mouse, rat POU3F3

    10 AceView cDNA sequences:

    NM_006236 F11569 BI464570 BF355891 BF341357 BF511732 AI796236 BG911951 
    BX418484 AF067777 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    POU3F3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACGCCGCCCG
    POU3F3 Expression
    About this image


    POU3F3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Kidney (Urinary System)    fully expand to see all 16 entries
             Loop of Henle Cells Loop of Henle
             Proximal Tubule
     
     Epithelial Cells
             Loop of Henle Cells Loop of Henle
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Thalamus
     
     Neural Tube (Nervous System)    fully expand to see all 5 entries
             Mesencephalic Ventricular Zone
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             Zeugopod Growth Plate
    POU3F3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    POU3F3 Protein Expression

    UniProtKB/Swiss-Prot: PO3F3_HUMAN, P20264
    Tissue specificity: Brain

        Pathway & Disease-focused RT2 Profiler PCR Arrays including POU3F3: 
              Neurogenesis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Homeobox (HOX) Genes in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU3F3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for POU3F3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pou3f31 , 5 POU domain, class 3, transcription factor 31, 5 89.54(n)1
    96.38(a)1
      1 (21.21 cM)5
    189931  NM_008900.21  NP_032926.21 
     426957685 
    lizard
    (Anolis carolinensis)
    Reptilia POU3F36
    POU class 3 homeobox 3
    83(a)
    1 ↔ 1
    GL343243.1(157682-159046)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004975071 POU domain, class 3, transcription factor 3-B-like 76.51(n)
    84.21(a)
      100497507  XM_004911792.1  XP_004911849.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Y07906.12   -- 76.06(n)   30386  Y07906.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta vvl3 peripheral nervous system development
    DNA binding
    81(a)
    (best of 3)
      3 65C5   --
    rice
    (Oryza sativa)
    Liliopsida AK060806.12   -- 73.23(n)    AK060806.1 


    ENSEMBL Gene Tree for POU3F3 (if available)
    TreeFam Gene Tree for POU3F3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for POU3F3 gene
    POU5F22  POU6F22  POU4F22  POU2F32  POU3F12  POU3F42  POU1F12  POU4F32  
    POU3F22  POU2F22  POU5F1B2  POU4F12  POU2F12  POU6F12  POU5F12  
    10 SIMAP similar genes for POU3F3 using alignment to 1 protein entry:     PO3F3_HUMAN:
    POU6F1    POU1F1    POU3F2    POU5F1P4    POU3F1    POU3F4
    POU2F1    POU4F3    POU2F3    POU4F1

    Find genes that share paralogs with POU3F3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for POU3F3 (see all 45)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs729476611,2
    C,F--105470075(+) TCTCTG/AGCGGG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1485060221,2
    C--105470243(+) GCGAAA/CGCCCA 1 -- us2k10--------
    rs1819834471,2
    --105470367(+) AGGACG/TACAGA 1 -- us2k10--------
    rs1145105361,2
    F--105470622(+) GTCAGA/TTCGGA 1 -- us2k11Minor allele frequency- T:0.01NA 120
    rs1995151441,2
    C--105470676(+) ACTTTA/C/G/
            
    CCTCT
    1 -- us2k10--------
    rs1418196281,2
    --105470761(+) CCAGCG/TCCCGC 1 -- us2k10--------
    rs1460611211,2
    --105471017(+) TTCTGC/TCCAAA 1 -- us2k10--------
    rs1863104321,2
    --105471184(+) CAGAGC/GGGGAG 1 -- us2k10--------
    rs1907937691,2
    --105471243(+) CACGCC/TTTCAA 1 -- us2k10--------
    rs1147163981,2
    F--105471270(+) CTACTC/TTAAGG 1 -- us2k11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for POU3F3 (105471969 - 105476929 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for POU3F3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2661949CNV Deletion23128226
    esv2660782CNV Deletion23128226
    nsv874757CNV Loss21882294
    nsv829587CNV Loss20364138
    nsv874756CNV Loss21882294
    dgv658n67CNV Gain20364138
    nsv829589CNV Gain20364138
    nsv829586CNV Gain20364138
    nsv829597CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing POU3F3
    DNA2.0 Custom Variant and Variant Library Synthesis for POU3F3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602480    OMIM disorders: --


    Find genes that share disorders with POU3F3           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: POU3F3 (1 document)

    Export disorders for POU3F3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for POU3F3 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with POU3F3)
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    1. Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals. (PubMed id 8703082)1, 2 Sumiyama K.... Ueda S. (J. Mol. Evol. 1996)
    2. Expression of a large family of POU-domain regulatory genes in mammalian brain development. (PubMed id 2739723)1, 2 He X....Rosenfeld M.G. (Nature 1989)
    3. Cooperative function of POU proteins and SOX proteins in glial cells. (PubMed id 9632656)1, 9 Kuhlbrodt K....Wegner M. (J. Biol. Chem. 1998)
    4. Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. (PubMed id 23006423)1 Niu N....Wang L. (BMC Cancer 2012)
    5. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (EMBO Rep. 2010)
    6. The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. (PubMed id 16582099)1 WissmA1ller S....Wegner M. (Nucleic Acids Res. 2006)
    7. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    9. Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2. (PubMed id 9457692)1 Sumiyama K....Ueda S. (Mamm. Genome 1998)
    10. The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U. (PubMed id 9105675)1 Malik K.F....Young W.S. (Brain Res. Mol. Brain Res. 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5455 HGNC: 9216 AceView: POU3F3 Ensembl:ENSG00000198914 euGenes: HUgn5455
    ECgene: POU3F3 H-InvDB: POU3F3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for POU3F3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for POU3F3 gene:
    Search GeneIP for patents involving POU3F3

    GeneCards and IP:
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