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POU3F1 Gene

protein-coding   GIFtS: 53
GCID: GC01M038509

POU Class 3 Homeobox 1

(Previous names: POU domain class 3, transcription factor 1)
(Previous symbol: OTF6)
  See POU3F1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3.2

Aliases
POU Class 3 Homeobox 11 2     POU Domain Transcription Factor SCIP2 3
OTF61 2 3     POU Domain Class 3, Transcription Factor 11
Octamer-Binding Protein 62 3     SCIP2
Octamer-Binding Transcription Factor 62 3     POU Domain, Class 3, Transcription Factor 12
OCT62 3     Oct-63
OTF-62 3     

External Ids:    HGNC: 92141   Entrez Gene: 54532   Ensembl: ENSG000001856687   OMIM: 6024795   UniProtKB: Q030523   
ORGUL members:    fRNAdb10:FR217284 FR044667 FR235515      
RNAdb15:EVF1924 EVF1926 EVF1925    

Export aliases for POU3F1 gene to outside databases

Previous GC identifers: GC01M038434 GC01M037517 GC01M037973 GC01M037923 GC01M038179 GC01M038282 GC01M036628


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for POU3F1 Gene:
POU3F1 (POU class 3 homeobox 1) is a protein-coding gene. Diseases associated with POU3F1 include schizophrenia. GO annotations related to this gene include RNA polymerase II transcription coactivator activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO3F1_HUMAN, Q03052
Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early
embryogenesis and neurogenesis

Gene Wiki entry for POU3F1 Gene

fRNAdb sequence ontology for POU3F1:
nc_conserved_region - Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for POU3F1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the POU3F1 gene promoter:
         NF-1/L   NF-1   GATA-3   SREBP-1c   SREBP-1b   GATA-1   Egr-4   SREBP-1a   HFH-1   Ik-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for POU3F1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POU3F1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.1   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

POU3F1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU3F1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M038509:  view genomic region     (about GC identifiers)

Start:
38,509,523 bp from pter      End:
38,512,450 bp from pter
Size:
2,928 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for POU3F1

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PO3F1_HUMAN, Q03052 (See protein sequence)
Recommended Name: POU domain, class 3, transcription factor 1  
Size: 451 amino acids; 45496 Da
Secondary accessions: Q5TAG2

Explore the universe of human proteins at neXtProt for POU3F1: NX_Q03052

Explore proteomics data for POU3F1 at MOPED


See POU3F1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_002690.3  
ENSEMBL proteins: 
 ENSP00000362103  

POU3F1 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
POU: Homeoboxes / POU class

Selected InterPro protein domains (see all 7):
 IPR010982 Lambda_DNA-bd_dom
 IPR016362 Transcription_factor_POU
 IPR013847 POU
 IPR000327 POU_specific
 IPR017970 Homeobox_CS

Graphical View of Domain Structure for InterPro Entry Q03052

ProtoNet protein and cluster: Q03052

2 Blocks protein domains:
IPB000327 POU domain
IPB013847 POU


UniProtKB/Swiss-Prot: PO3F1_HUMAN, Q03052
Similarity: Belongs to the POU transcription factor family. Class-3 subfamily
Similarity: Contains 1 homeobox DNA-binding domain
Similarity: Contains 1 POU-specific domain


Find genes that share domains with POU3F1           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: PO3F1_HUMAN, Q03052
Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early
embryogenesis and neurogenesis

     Genatlas biochemistry entry for POU3F1:
POU domain,class 3,transcription factor 1

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001105RNA polymerase II transcription coactivator activity IEA--
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IDA9242494
     
Find genes that share ontologies with POU3F1           About GenesLikeMe


Phenotypes:
     9 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Pou3f1):
 behavior/neurological  growth/size/body  homeostasis/metabolism  integument  mortality/aging 
 nervous system  no phenotypic analysis  normal  respiratory system 

Find genes that share phenotypes with POU3F1           About GenesLikeMe

Animal Models:
     MGI mouse knock-outs for POU3F1: Pou3f1tm2.1Mejr Pou3f1tm2Mejr

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POU3F1
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miRNA
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Selected qRT-PCR Assays for microRNAs that regulate POU3F1 (see all 64):
hsa-miR-323-3p hsa-miR-1224-3p hsa-miR-218-1* hsa-miR-1260b hsa-miR-138-2* hsa-miR-342-3p hsa-miR-502-3p hsa-miR-629*
SwitchGear 3'UTR luciferase reporter plasmidPOU3F1 3' UTR sequence
Inhib. RNA
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Gene Editing
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU3F1


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
PO3F1_HUMAN, Q03052: Nucleus
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
cytosol2

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus ISS--
GO:0005667transcription factor complex IEA--

Find genes that share ontologies with POU3F1           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for POU3F1 About    
See pathways by source

SuperPathContained pathways About
1Transcription factors in neurogenesis
Transcription factors in neurogenesis



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for POU3F1
Interactions:

    GeneGlobe Interaction Network for POU3F1

STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

Selected Interacting proteins for POU3F1 (Q030523 ENSP000003621034) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
InteractantInteraction Details
GeneCardExternal ID(s)
HMGA1P170963, ENSP000003082274I2D: score=2 STRING: ENSP00000308227
HMGB2P265833, ENSP000002965034I2D: score=1 STRING: ENSP00000296503
POU3F4P493353, ENSP000003622964I2D: score=2 STRING: ENSP00000362296
POU3F2P202653I2D: score=1 
POU3F3P202643I2D: score=1 
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Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006355regulation of transcription, DNA-templated ----
GO:0008366axon ensheathment TAS8662541
GO:0008544epidermis development ----
GO:0010628positive regulation of gene expression ISS--
GO:0014044Schwann cell development ----

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for POU3F1 (PO3F1)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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3 fRNAdb Secondary structures:


REFSEQ mRNAs for POU3F1 gene: 
NM_002699.3  

Unigene Cluster for POU3F1:

POU class 3 homeobox 1
Hs.1837  [show with all ESTs]
Unigene Representative Sequence: NM_002699
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000373012(uc001ccp.1)
miRNA
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Selected qRT-PCR Assays for microRNAs that regulate POU3F1 (see all 64):
hsa-miR-323-3p hsa-miR-1224-3p hsa-miR-218-1* hsa-miR-1260b hsa-miR-138-2* hsa-miR-342-3p hsa-miR-502-3p hsa-miR-629*
SwitchGear 3'UTR luciferase reporter plasmidPOU3F1 3' UTR sequence
Inhib. RNA
Products:
     
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Predesigned siRNA for gene silencing in human, mouse, rat POU3F1
Clone
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POU3F1
Primer
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  QuantiTect SYBR Green Assays in human, mouse, rat POU3F1
  QuantiFast Probe-based Assays in human, mouse, rat POU3F1

Additional mRNA sequence: 

L26494.1 S81257.1 

3 DOTS entries:

DT.303774  DT.92417853  DT.100697072 

14 AceView cDNA sequences:

CR611990 BE326578 H89079 AL583550 AI807330 BF438187 AL565480 L26494 
NM_002699 AA341505 S81257 Z18284 BQ276805 BU960108 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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POU3F1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TAAATATGTG
POU3F1 Expression
About this image


POU3F1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 9) fully expand
 
 Peripheral Nervous System (Nervous System)    fully expand to see all 4 entries
         Pro-myelinating Schwann Cells Peripheral Nerve Domain
         Schwann cells
         Schwann-like cells
 
 Schwann Cells (Nervous System)    fully expand to see all 2 entries
         Schwann cells
         Schwann-like cells
 
 Brain (Nervous System)    fully expand to see all 5 entries
         Myelinating Oligodendrocyte Cells Forebrain White Matter
         Cerebral Cortex
         N2/LSB/S/F8-induced cells
 
 Epiblast (Early Embryonic Tissues)    fully expand to see all 2 entries
         Epiblast Cells Epiblast
         Epiblast-like cells
 
 Thymus (Hematopoietic System)
         Thymus
POU3F1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

POU3F1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.1837

UniProtKB/Swiss-Prot: PO3F1_HUMAN, Q03052
Tissue specificity: Expressed in embryonal stem cells and in the developing brain

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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for POU3F1 gene from Selected species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Pou3f15 POU domain, class 3, transcription factor 1   --   4 (57.86 cM) 124656807 
African clawed frog
(Xenopus laevis)
Amphibia pou1-A2 POU 1 transcription factor 76.91(n)    BC043847.1 
zebrafish
(Danio rerio)
Actinopterygii pou3f16
POU class 3 homeobox 1
69(a)
many ↔ many
16(35906777-35909646) ENSDARG00000009823
fruit fly
(Drosophila melanogaster)
Insecta vvl3 peripheral nervous system development
DNA binding
83(a)
(best of 3)
  3 65C5   --


ENSEMBL Gene Tree for POU3F1 (if available)
TreeFam Gene Tree for POU3F1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for POU3F1 gene
POU5F22  POU6F22  POU4F22  POU2F32  POU3F42  POU1F12  POU3F32  POU4F32  
POU3F22  POU2F22  POU5F1B2  POU4F12  POU2F12  POU6F12  POU5F12  
17 SIMAP similar genes for POU3F1 using alignment to 1 protein entry:     PO3F1_HUMAN:
OCT6    POU2F1    POU6F1    POU1F1    OCT-2    POU4F1
POU2F3    POU3F4    POU4F3    POU2F2    POU3F2    POU3F3
POU5F1    POU5F1P4    POU5F1P1    POU4F2    POU5F1B

Find genes that share paralogs with POU3F1           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for POU3F1 (see all 33)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1897140351,2
--38509090(+) TGAAAA/GTTGGG 1 -- ds50010--------
rs729308661,2
C--38509157(+) GGGCTG/TCTTTC 1 -- ds50011Minor allele frequency- T:0.50WA 2
rs761652461,2
--38509187(+) GAGTTA/GTGCAT 1 -- ds50010--------
rs1152049831,2
F--38509273(+) TGTCTA/GCGACA 1 -- ds50011Minor allele frequency- G:0.01NA 120
rs1392728951,2
--38509283(+) AGGGGA/GACACG 1 -- ds50010--------
rs2008798581,2
C--38509576(+) CATTA-/TTTTTT 1 -- ut310--------
rs412682511,2
--38509676(+) AAACAC/GAAGAA 1 -- ut310--------
rs284189841,2
C--38509884(+) ATCTCA/CCATAT 1 -- ut312Minor allele frequency- C:0.00NA 4
rs348603891,2
C--38510154(+) GCAGAA/GGCCCC 1 -- ut314Minor allele frequency- G:0.33NA WA EA 360
rs1380249791,2
--38510267(+) TGTTA-/GTTTTT 1 -- ut310--------

HapMap Linkage Disequilibrium report for POU3F1 (38509523 - 38512450 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for POU3F1:    About this table    
Variant IDTypeSubtypePubMed ID
nsv522CNV Insertion18451855

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing POU3F1
DNA2.0 Custom Variant and Variant Library Synthesis for POU3F1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 602479OMIM information:   
1 disease for POU3F1:    
About MalaCards
schizophrenia


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1 Novoseek inferred disease relationship for POU3F1 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
schizophrenia 6.76 2 16246257 (1), 15006499 (1)

Genetic Association Database (GAD): POU3F1

Export disorders for POU3F1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for POU3F1 gene, integrated from 10 sources (see all 44):
(articles sorted by number of sources associating them with POU3F1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart. (PubMed id 8451175)1, 2, 3 Tobler A.... Fontana A. (Nucleic Acids Res. 1993)
  2. Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia. (PubMed id 7909356)1, 2, 9 Faus I.... Fuchs E. (Mol. Cell. Biol. 1994)
  3. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. (PubMed id 20453842)1, 4 Stahl E.A....Plenge R.M. (Nat. Genet. 2010)
  4. Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies. (PubMed id 12557005)1, 9 Kawasaki T....Shibasaki H. (Acta Neuropathol. 2003)
  5. Expression and activity of the POU transcription factor SCIP. (PubMed id 1975954)1, 9 Monuki E.S....Lemke G. (Science 1990)
  6. Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation. (PubMed id 17195013)1, 9 Beck I.M....Sedlacek R. (J. Invest. Dermatol. 2007)
  7. Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. (PubMed id 23192594)1 Velez Edwards D.R....Edwards T.L. (Hum. Genet. 2013)
  8. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (PLoS Genet. 2012)
  9. Aberrant CpG island hypermethylation and down-regulation of Oct-6 mRNA expression in human hepatocellular carcinoma. (PubMed id 21448695)1 Sun J.Z....Li M. (Dig. Dis. Sci. 2011)
  10. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (BMC Med. Genet. 2007)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 5453 HGNC: 9214 AceView: POU3F1 Ensembl:ENSG00000185668 euGenes: HUgn5453
ECgene: POU3F1 H-InvDB: POU3F1

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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for POU3F1 Pharmacogenomics, SNPs, Pathways

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