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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POU2F3 Gene

protein-coding   GIFtS: 56
GCID: GC11P120144

POU Class 2 Homeobox 3

(Previous names: POU domain class 2, transcription factor 3)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
POU Class 2 Homeobox 31 2     Epoc-12
Octamer-Binding Protein 112 3     OCT-112
Octamer-Binding Transcription Factor 112 3     PLA-12
Transcription Factor PLA-12 3     Skn-1a2
Transcription Factor Skn-12 3     POU Domain Transcription Factor OCT11a2
OTF-112 3     POU Domain, Class 2, Transcription Factor 32
PLA12 3     OTF113
OCT112 5     Oct-113
POU Domain Class 2, Transcription Factor 31     

External Ids:    HGNC: 198641   Entrez Gene: 258332   Ensembl: ENSG000001377097   OMIM: 6073945   UniProtKB: Q9UKI93   

Export aliases for POU2F3 gene to outside databases

Previous GC identifers: GC11P122110 GC11P121622 GC11P119648 GC11P119616 GC11P116050


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for POU2F3 Gene:
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors
bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded
protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and
differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter
methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding
multiple isoforms have been observed for this gene. (provided by RefSeq, Sep 2011)

GeneCards Summary for POU2F3 Gene: 
POU2F3 (POU class 2 homeobox 3) is a protein-coding gene. Diseases associated with POU2F3 include cervical cancer, and coronary thrombosis, and among its related super-pathways are Influenza A. GO annotations related to this gene include protein dimerization activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is POU5F2.

UniProtKB/Swiss-Prot: PO2F3_HUMAN, Q9UKI9
Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a
number of genes such as SPRR2A or placental lactogen

Gene Wiki entry for POU2F3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POU2F3 gene promoter:
         E2F-4   E2F-3a   E2F-5   RelA   E2F-2   LCR-F1   E2F   E2F-1   ZIC2/Zic2   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPOU2F3 promoter sequence
   Search SABiosciences Chromatin IP Primers for POU2F3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU2F3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q23.3

POU2F3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POU2F3 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P120144:  view genomic region     (about GC identifiers)

Start:
120,107,349 bp from pter      End:
120,190,653 bp from pter
Size:
83,305 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PO2F3_HUMAN, Q9UKI9 (See protein sequence)
Recommended Name: POU domain, class 2, transcription factor 3  
Size: 436 amino acids; 47432 Da
Subcellular location: Nucleus
Secondary accessions: A8K7H8 B4DY07 F5GWW6 Q3MIY3 Q9UKR7 Q9Y504
Alternative splicing: 3 isoforms:  Q9UKI9-1   Q9UKI9-2   Q9UKI9-3   (Specifically expressed in keratinocytes, induced by high calcium concentration)

Explore the universe of human proteins at neXtProt for POU2F3: NX_Q9UKI9

Explore proteomics data for POU2F3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UKI9

  • POU2F3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    POU2F3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001231611.1  NP_055167.2  

    ENSEMBL proteins: 
     ENSP00000260264   ENSP00000441687   ENSP00000435738   ENSP00000453150  

    Human Recombinant Protein Products for POU2F3: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005667transcription factor complex IEA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    POU2F3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    POU: Homeoboxes / POU class

    5/7 InterPro protein domains (see all 7):
     IPR010982 Lambda_DNA-bd_dom
     IPR000972 TF_octamer
     IPR013847 POU
     IPR000327 POU_specific
     IPR017970 Homeobox_CS

    Graphical View of Domain Structure for InterPro Entry Q9UKI9

    ProtoNet protein and cluster: Q9UKI9

    3 Blocks protein domains:
    IPB000327 POU domain
    IPB000972 Octamer-binding transcription factor signature
    IPB013847 POU


    UniProtKB/Swiss-Prot: PO2F3_HUMAN, Q9UKI9
    Similarity: Belongs to the POU transcription factor family. Class-2 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 POU-specific domain


    POU2F3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PO2F3_HUMAN, Q9UKI9
    Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a
    number of genes such as SPRR2A or placental lactogen

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding IPI12624109
    GO:0043565sequence-specific DNA binding IDA9242494
    GO:0046983protein dimerization activity IEA--
         
    POU2F3 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Pou2f3):
     behavior/neurological  cellular  integument  mortality/aging  taste/olfaction 

    POU2F3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for POU2F3: Pou2f3tm1Rsd Pou2f3tm1Abek

       inGenious Targeting Laboratory - Custom generated mouse model solutions for POU2F3 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for POU2F3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for POU2F3 

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    SwitchGear 3'UTR luciferase reporter plasmidPOU2F3 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU2F3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for POU2F3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Influenza A
    Herpes simplex infection0.33

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for POU2F3):
        Herpes simplex infection


    POU2F3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POU2F3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for POU2F3 (Q9UKI93 ENSP000002602644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREBBPQ927933, ENSP000002623674I2D: score=2 STRING: ENSP00000262367
    BCL6P411823, ENSP000002320144I2D: score=3 STRING: ENSP00000232014
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS10473598
    GO:0008544epidermis development TAS10473598
    GO:0030216keratinocyte differentiation IEA--

    POU2F3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    POU2F3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for POU2F3 (PO2F3)

    4 Novoseek inferred chemical compound relationships for POU2F3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phospholipid 26.9 3 2000640 (2), 2253331 (1)
    retinoic acid 2.16 1 15545507 (1)
    zinc 0 1 8816448 (1)
    heparin 0 3 8485868 (2)

    Search CenterWatch for drugs/clinical trials and news about POU2F3 / PO2F3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for POU2F3 gene (2 alternative transcripts): 
    NM_001244682.1  NM_014352.3  

    Unigene Cluster for POU2F3:

    POU class 2 homeobox 3
    Hs.227115  [show with all ESTs]
    Unigene Representative Sequence: NM_014352
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000260264(uc021qrk.1 uc001pxc.3 uc010rzk.2 uc010rzl.2 uc001pxe.1)
    ENST00000543440 ENST00000533620 ENST00000606153 ENST00000532638 ENST00000532663
    ENST00000529039
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/32 QIAGEN miScript miRNA Assays for microRNAs that regulate POU2F3 (see all 32):
    hsa-miR-498 hsa-miR-3673 hsa-miR-607 hsa-miR-1271 hsa-miR-128 hsa-miR-450b-3p hsa-miR-3692 hsa-miR-10b*
    SwitchGear 3'UTR luciferase reporter plasmidPOU2F3 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF133895.1 AF162278.1 AJ012214.1 AK097382.1 AK291993.1 AK302212.1 BC101649.1 BC143593.1 
    BC143594.1 BC143595.1 

    5 DOTS entries:

    DT.422614  DT.100008374  DT.91731669  DT.100767682  DT.40190810 

    24/84 AceView cDNA sequences (see all 84):

    BQ573722 AI822098 CA778080 CR602717 AW297273 AL531164 AA422067 BM971471 
    CR593728 BU151499 BX281405 AW361691 BQ690587 NM_174926 BC015232 BQ346614 
    AF133895 NM_014352 AK097382 AF162715 AJ012214 BG707889 N74690 BU845205 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    POU2F3 expression in normal human tissues (normalized intensities)      POU2F3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTAGGAAAC
    POU2F3 Expression
    About this image


    POU2F3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)
             Line H9 (WA09)
     
     Brain (Nervous System)
             Trigeminal Ganglion   
     
     Colon (Gastrointestinal Tract)

     -- (Integumentary System)
             skin   

    See POU2F3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for POU2F3

    SOURCE GeneReport for Unigene cluster: Hs.227115

    UniProtKB/Swiss-Prot: PO2F3_HUMAN, Q9UKI9
    Tissue specificity: Specifically expressed in epidermis and cultured keratinocytes

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU2F3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for POU2F3 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pou2f31 , 5 POU domain, class 2, transcription factor 31, 5 90.44(n)1
    93.47(a)1
      9 (24.21 cM)5
    189881  NM_011139.21  NP_035269.21 
     431226285 
    chicken
    (Gallus gallus)
    Aves POU2F31 POU class 2 homeobox 3 77.73(n)
    80.61(a)
      428240  XM_425799.3  XP_425799.3 
    lizard
    (Anolis carolinensis)
    Reptilia POU2F36
    Uncharacterized protein
    77(a)
    1 ↔ 1
    LGa(1316547-1348136)
    zebrafish
    (Danio rerio)
    Actinopterygii pou2f31 POU class 2 homeobox 3 66.67(n)
    67.35(a)
      553427  NM_001199683.1  NP_001186612.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta pdm26
    nub6
    nubbin
    17(a)
    16(a)
    many ↔ many
    many ↔ many
    2L(12657829-12686313)
    2L(12587871-12628143)


    ENSEMBL Gene Tree for POU2F3 (if available)
    TreeFam Gene Tree for POU2F3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for POU2F3 gene
    POU5F22  POU6F22  POU4F22  POU3F12  POU3F42  POU1F12  POU3F32  POU4F32  
    POU3F22  POU2F22  POU5F1B2  POU4F12  POU2F12  POU6F12  POU5F12  
    14 SIMAP similar genes for POU2F3 using alignment to 4 protein entries:     PO2F3_HUMAN (see all proteins):
    OCT6    OCT-2    POU6F1    POU5F1P4    POU2F2    POU1F1
    POU2F1    POU3F4    POU3F1    POU5F1P1    POU3F2    POU5F1
    POU4F3    POU3F3

    POU2F3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1137/1710 SNPs in POU2F3 are shown (see all 1710)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349299891,2
    C--116063544(+) TTTTTT/-GAGAT 2 -- int11Minor allele frequency- -:0.50NA 2
    rs113067711,2
    C,F--116071424(+) CATGGT/-TTTTT 2 -- int1 trp34Minor allele frequency- -:0.38NA CSA 8
    rs347003211,2
    C--116073242(+) ATTTAATTT/-  
            
    ATTTA
    2 -- int11Minor allele frequency- -:0.50NA 2
    rs112177781,2
    --116073245(+) TAATTA/TATTTA 2 -- int10--------
    rs1812681141,2
    --116073249(+) TTATTA/TATTTA 2 -- int10--------
    rs1855817381,2
    --116073253(+) TTATTA/TATTTA 2 -- int10--------
    rs105380401,2
    C--116073267(+) attta-/T/    
       TTTAT
    ttatt
    2 -- int11NA 2
    rs1415598411,2
    C--116073267(+) ATTTA-/TTTAT 
            
    TTATT
    2 -- int10--------
    rs351867451,2
    C--116074470(+) CTCAT-/ACAC  
            
    ACACA
    2 -- int10--------
    rs586095711,2
    C--116078392(+) TTAAAGCT/-ACAGG 2 -- cds11Minor allele frequency- -:0.50CSA 2
    rs675351271,2
    C--116078393(+) TAAAA-/CT    
       C
    /GCT
    CAGGG
    4 -- cds10--------
    rs1996569331,2
    C--116079082(+) TTATG-/TATT  
            
    TATTT
    2 -- int10--------
    rs1476985671,2
    --116079086(+) TGTATG/TTATTT 2 -- int10--------
    rs57952221,2
    C--116084772(+) AAAAG-/AAAAAA 2 -- int1 trp31Minor allele frequency- A:0.00CSA 2
    rs776898391,2
    C--116094702(+) ATGGA-/GGCAAG 2 -- int10--------
    rs350397951,2
    C--116096647(+) TTTTTT/-CTGAG 2 -- int12Minor allele frequency- -:0.25NA 4
    rs2001484671,2
    --116113934(+) CCATC-/TTAGTG 2 -- int10--------
    rs1140355661,2
    C--116113936(+) CATCTA/GGTGGT 2 -- int10--------
    rs730066761,2
    C--116115073(+) AAAAAG/AAAGAA 2 -- int11Minor allele frequency- A:0.50WA 2
    rs112178081,2
    --116115077(+) AAAAAA/GAAGAA 2 -- int1 trp31Minor allele frequency- G:0.00NA 2
    rs341154121,2
    C--116126606(+) TTTTT-/TGAGAC 2 -- int11Minor allele frequency- T:0.00NA 2
    rs57952261,2
    C--116128452(+) GTGAGC/-CCAGA 2 -- int12Minor allele frequency- -:0.00NA 4
    rs1152629671,2
    F--119971266(+) GGAATC/TGCTAC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs79341341,2
    C,F,H--119971450(+) TCCCAC/TGGGGA 1 -- us2k113Minor allele frequency- T:0.09NS EA NA WA 1878
    rs1927292091,2
    C--119971545(+) CCAACA/GGGCCA 1 -- us2k10--------
    rs798412671,2
    F--119971609(+) AACTAG/AGGTTC 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs118233371,2
    C,H--119971636(+) CTTTGA/GTGGGG 1 -- us2k10--------
    rs1461655531,2
    --119971738(+) AGCCAC/TGGATG 1 -- us2k10--------
    rs1389941951,2
    --119971763(+) AAGATC/GTCTCC 1 -- us2k10--------
    rs1415347641,2
    --119971972(+) ATCCAG/TCTCAG 1 -- us2k10--------
    rs9479061,2
    C,F,A,H--119971989(+) TGCCGG/TCCTCA 1 -- us2k114Minor allele frequency- T:0.15NS EA NA WA CSA 842
    rs1507113021,2
    --119971999(+) AAAGTC/TAAAAA 1 -- us2k10--------
    rs1173218341,2
    C,F--119972051(+) TAAATA/GTATGT 1 -- us2k11Minor allele frequency- G:0.04NA 120
    rs1159830551,2
    F--119972273(+) ATCCTG/AGTTCC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1830806931,2
    --119972313(+) ACGAAC/TCCCAC 1 -- us2k10--------
    rs1884684771,2
    --119972337(+) CTCCCA/GGCAAT 1 -- us2k10--------
    rs1163508561,2
    F--119972513(+) GGCCCC/TATGGC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1391006001,2
    C--119972588(+) TCTCCA/GCCCTT 1 -- us2k10--------
    rs1494924771,2
    --119972619(+) ATCCAC/GCTGAC 1 -- us2k10--------
    rs1930462201,2
    --119972794(+) CTGTCC/TTTGAA 1 -- us2k10--------
    rs1439396361,2
    C--119972902(+) GACCCC/TGGAGG 1 -- us2k10--------
    rs1157148671,2
    F--119972926(+) TCAGAA/GTTGAT 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1141743771,2
    F--119972950(+) CCACAG/ACATCC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1842853691,2
    --119972956(+) CATCCC/TGGAGT 1 -- us2k10--------
    rs1894458341,2
    --119972965(+) GTAAGG/TCTTCT 1 -- us2k10--------
    rs13162811,2
    C,F--119973016(+) GGTAAG/AGGAGG 1 -- us2k1 trp31Minor allele frequency- A:0.01WA 118
    rs1140472901,2
    F--119973020(+) AGGGAG/CGGAGG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1924908881,2
    --119973119(+) TTTCCC/TTTTCT 1 -- us2k10--------
    rs1405524521,2
    C--119973237(+) GTTGAC/TATTTT 1 -- us2k10--------
    rs1152042451,2
    F--119973256(+) TCTCAC/TTCCAG 1 -- ut511Minor allele frequency- T:0.01WA 118
    rs1836412021,2
    --119973266(+) GCCCAA/GAGCTC 1 -- ut510--------
    rs1443961261,2
    C--119973274(+) CTCAAA/GAAACC 1 -- ut510--------
    rs1478519451,2
    --119973299(+) TCCAAC/GAACTG 2 T R mis10--------
    rs1892587631,2
    --119973303(+) AGAACC/TGCTAA 2 T syn10--------
    rs8828561,2
    C,F,H--119973314(+) AGGAGG/AAAGGG 2 /E /G mis1 trp323Minor allele frequency- A:0.35NS EA NA WA 2482
    rs571395841,2
    C,F--119973326(+) TAAAGG/CAGTTC 1 -- int11Minor allele frequency- C:0.50WA 2
    rs1813465461,2
    C--119973334(+) TTCTCC/TACGTT 1 -- int10--------
    rs1422822421,2
    --119973337(+) TCTACA/GTTCCC 1 -- int10--------
    rs1144114591,2
    C,F--119973350(+) TCTAGC/GTCATC 1 -- int11Minor allele frequency- G:0.03WA 118
    rs1164323851,2
    C,F--119973354(+) GCTCAT/CCTAAC 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1863573761,2
    --119973366(+) GAAATA/GATCAG 1 -- int10--------
    rs1895040401,2
    --119973372(+) ATCAGC/TGAGCA 1 -- int10--------
    rs603614981,2
    C,F--119973382(+) AAGTCG/TGAGAG 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1816854621,2
    --119973392(+) GAGAAA/GGAATA 1 -- int10--------
    rs1144644331,2
    F--119973393(+) AGAAGG/TAATAA 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1860822131,2
    --119973417(+) TTCCCC/TCTCAA 1 -- int10--------
    rs1404355941,2
    --119973418(+) TCCCCC/TTCAAC 1 -- int10--------
    rs1911949371,2
    --119973427(+) ACCCTA/GTACAC 1 -- int10--------
    rs1818000931,2
    C--119973457(+) CCCCAA/GCCTTC 1 -- int10--------
    rs1504419811,2
    C--119973478(+) GGCACA/GTGAGG 1 -- int10--------
    rs1175974651,2
    F--119973487(+) GGGAGA/GAGCAG 1 -- int11Minor allele frequency- G:0.01EA 120
    rs2003998811,2
    C--119973521(+) GAGCC-/ATATGTT 1 -- int10--------
    rs13206781,2
    C,F,A,H--119973547(+) GGGTAA/TGTCCC 1 -- int1 tfbs31Minor allele frequency- T:0.03NA 120
    rs1465745541,2
    --119973591(+) GGTTCA/GATGAT 1 -- int10--------
    rs1154922841,2
    F--119973592(+) GTTCAA/GTGATA 1 -- int11Minor allele frequency- G:0.02WA 118
    rs1853273931,2
    --119973636(+) GAAGGA/GGAAGC 1 -- int10--------
    rs1909268751,2
    --119973640(+) GGGAAA/GCTCAG 1 -- int10--------
    rs79496841,2
    C,F--119973806(+) agtggC/Tactga 1 -- int11Minor allele frequency- T:0.09WA 118
    rs1144141881,2
    F--119973879(+) TCTATA/GTTCAT 1 -- int11Minor allele frequency- G:0.05WA 118
    rs1830728631,2
    --119973956(+) TGCCCC/TGTTCA 1 -- int10--------
    rs782377821,2
    C,F--119974170(+) AAAACT/CAAAGC 1 -- int13Minor allele frequency- C:0.04WA NA 240
    rs1884069801,2
    --119974223(+) GCCCCA/GGATAA 1 -- int10--------
    rs1910999661,2
    --119974912(+) GGAGCA/GTGGGG 2 -- us2k1 int10--------
    rs1441281661,2
    C--119975054(+) TTCTA-/GGT   
       GCTGG
    GGTGC
    2 -- us2k1 int10--------
    rs1413554011,2
    --119975106(+) CCAGGA/GGGTAA 2 -- us2k1 int10--------
    rs1830605981,2
    --119975220(+) GAGGCA/GGGTGG 2 -- us2k1 int10--------
    rs1873469151,2
    --119975222(+) GGCGGC/GTGGAT 2 -- us2k1 int10--------
    rs1924920371,2
    --119975233(+) CACGAA/GGTCAG 2 -- us2k1 int10--------
    rs562910801,2
    --119975234(+) ACGAGA/GTCAGG 2 -- us2k1 int10--------
    rs108925521,2
    A--119975328(+) atagtC/Ttcagc 2 -- us2k1 int10--------
    rs1845922211,2
    --119975380(+) GAGGTA/TGCAGT 2 -- us2k1 int10--------
    rs1876426171,2
    --119975413(+) CTCCAA/GCCTGG 2 -- us2k1 int10--------
    rs118202771,2
    C,H--119975416(+) cagccC/Tggcaa 2 -- us2k1 int10--------
    rs1494213801,2
    --119975475(+) CACGGA/GACTTA 2 -- us2k1 int10--------
    rs1927816011,2
    --119975538(+) AATGTA/GCAGGT 2 -- us2k1 int10--------
    rs1842230001,2
    --119975633(+) ACGAAA/GTGCTG 2 -- us2k1 int10--------
    rs1900294371,2
    C--119975651(+) TCGTGA/GGCATG 2 -- us2k1 int10--------
    rs1168321551,2
    F--119975652(+) CGTGGG/TCATGA 2 -- us2k1 int11Minor allele frequency- T:0.04WA 118
    rs1438089861,2
    --119975654(+) TGGGCA/TTGACT 2 -- us2k1 int10--------
    rs618982971,2
    F--119975668(+) GTGCAC/TGGTGG 2 -- us2k1 int12Minor allele frequency- T:0.02NA 122
    rs1123327431,2
    C,F--119975669(+) TGCACG/AGTGGG 2 -- us2k1 int14Minor allele frequency- A:0.25WA CSA 123
    rs1151084811,2
    C,F--119975695(+) GGAAAG/AGACAC 2 -- us2k1 int11Minor allele frequency- A:0.09WA 118
    rs1479883411,2
    C--119975786(+) TGTTCA/GTGAGG 2 -- us2k1 int10--------
    rs1812296081,2
    --119975798(+) GTCCTA/GTCTGG 2 -- us2k1 int10--------
    rs1416266711,2
    C--119975859(+) CCATGC/TAGGCC 2 -- us2k1 int10--------
    rs25096231,2
    C,F,A,H--119975869(+) CATCCC/TGTGGT 2 -- us2k1 int125Minor allele frequency- T:0.12NS EA NA WA CSA 2353
    rs1845702881,2
    --119975904(+) AGAGAC/TGAAGA 2 -- us2k1 int10--------
    rs1888893841,2
    --119975939(+) GCTGCA/CAAGAG 2 -- us2k1 int10--------
    rs1819903051,2
    --119976089(+) ATCTCA/GTAGAG 2 -- us2k1 int10--------
    rs1505460311,2
    --119976106(+) AGCAAC/TCTGGG 2 -- us2k1 int10--------
    rs27158901,2
    C,F,A,H--119976121(+) GGGGCC/GGGAGA 2 -- us2k1 int114Minor allele frequency- G:0.46NS EA WA NA CSA 779
    rs1872475391,2
    --119976424(+) CCAACC/TCCTTG 2 -- us2k1 int10--------
    rs1919190651,2
    --119976432(+) TTGCAG/TCGCTT 2 -- us2k1 int10--------
    rs108925531,2
    C,F--119976677(+) GGGCCT/CGGGGC 2 -- us2k1 int1 tfbs34Minor allele frequency- C:0.18NA WA CSA 125
    rs107903711,2
    C,A,H--119976943(+) GCCCCG/CCCTGG 2 -- ut51 int14Minor allele frequency- C:0.14NA WA EA 360
    rs1403551121,2
    --119977041(+) TGAAGA/GAGAGG 2 -- int10--------
    rs1138175671,2
    C,F--119977053(+) ACAACG/ATTCTG 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs1810165221,2
    --119977129(+) GGTGGC/GTGCCG 2 -- int10--------
    rs1475190371,2
    C--119977508(+) CCCCC-/AATGTG 2 -- int10--------
    rs1450899301,2
    --119977583(+) GGGTGA/GAAACC 2 -- int10--------
    rs1859539211,2
    C--119977726(+) CCAGGC/TAGCCA 2 -- int10--------
    rs1915972701,2
    --119977747(+) GGCTTG/TGGGCT 2 -- int10--------
    rs22530061,2
    C,A,H--119977755(+) GCTTCG/CTGTTA 2 -- int113Minor allele frequency- C:0.14NA WA CSA EA 377
    rs1823663231,2
    --119978001(+) ACCCAA/GCCTGA 2 -- int10--------
    rs1485189221,2
    --119978032(+) CCGGAA/GGGAGG 2 -- int10--------
    rs1874431781,2
    --119978220(+) GACTGA/GGCATA 2 -- int10--------
    rs730066671,2
    --119978244(+) CCCGGG/TTAGGT 2 -- int10--------
    rs1903556501,2
    --119978337(+) GGGAAA/GTTTTT 2 -- int10--------
    rs612478081,2
    C,F--119978339(+) GAAGTT/ATTTTA 2 -- int12Minor allele frequency- A:0.04WA 120
    rs1465780351,2
    --119978364(+) GACTTC/TCTGGG 2 -- int10--------
    rs1150275011,2
    C,F--119978370(+) CTGGGG/CGTTTT 2 -- int11Minor allele frequency- C:0.20WA 118
    rs1828270851,2
    --119978552(+) AGCTCC/TTGGCT 2 -- int10--------
    rs28474971,2
    C,F,A,H--119978602(+) CCTGTG/TAGCAG 2 -- int119Minor allele frequency- T:0.17NS EA NA CSA WA 2342
    rs1412830201,2
    C--119978623(+) CACATC/GGGGGG 2 -- int10--------
    rs1157747441,2
    F--119978796(+) CCTCTG/ATAGTG 2 -- int11Minor allele frequency- A:0.03WA 118
    rs1891634321,2
    --119978801(+) GTAGTG/TTCTGA 2 -- int10--------
    rs1451168991,2
    C--119978872(+) TCTAAA/CTGGGT 2 -- int10--------
    rs1468576971,2
    --119978903(+) TGCTGG/TGTCCT 2 -- int10--------
    rs578592711,2
    C,F--119978934(+) AAGATC/GTTCTT 2 -- int14Minor allele frequency- G:0.06WA CSA 122
    rs1930923191,2
    --119978957(+) CAGTGC/TGCACC 2 -- int10--------
    rs1151444991,2
    C,F--119979021(+) TATGGG/ATCCCT 2 -- int11Minor allele frequency- A:0.03WA 118
    rs122785531,2
    C,F,H--119979120(+) ACTGAT/GCTTGA 2 -- int14Minor allele frequency- G:0.00NS EA 418
    rs1846414161,2
    --119979258(+) GCTCCC/TGGGTC 2 -- int10--------
    rs1874589691,2
    C--119979268(+) CGCCCA/GCTCCA 2 -- int10--------
    rs1504949071,2
    --119979285(+) CCACTC/GGCACT 2 -- int10--------
    rs1383214921,2
    --119979311(+) TAGCCA/CCATTG 2 -- int10--------
    rs1490348341,2
    --119979559(+) GGAAGC/GCAGCG 2 -- int10--------
    rs28457021,2
    C,F,A,H--119979564(+) CCAGCT/GGGCGG 2 -- int111Minor allele frequency- G:0.18NA WA EA 378
    rs28474981,2
    C,F,A,H--119979567(+) GCTGGC/TGGGGG 2 -- int18Minor allele frequency- T:0.44NA WA 256
    rs1165232791,2
    F--119979633(+) TTTCCC/TCACCA 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1457410001,2
    C--119979680(+) GCCAAC/TTGGAG 2 -- int10--------
    rs1387425941,2
    --119979698(+) ATAGCA/GTTTGG 2 -- int10--------
    rs1158354591,2
    C,F--119979730(+) ACTGAG/AAAGAA 2 -- int11Minor allele frequency- A:0.03WA 118
    rs1427713871,2
    --119979804(+) GTCCTC/TTGAAG 2 -- int10--------
    rs1917931841,2
    C--119979972(+) TGCAGC/TCTGTG 2 -- int10--------
    rs28474991,2
    C,F,A,H--119979976(+) GCCTGG/TGGGGA 2 -- int119Minor allele frequency- T:0.06NS EA WA NA CSA 1384
    rs1840545621,2
    --119979978(+) CTGTGA/GGGAGT 2 -- int10--------
    rs1125028491,2
    C--119980008(+) TCCCT-/GGGGTT 2 -- int11Minor allele frequency- G:0.00CSA 2
    rs1125252211,2
    F--119980020(+) ACAGAC/TGTCTA 2 -- int11Minor allele frequency- T:0.50CSA 2
    rs1381581621,2
    --119980114(+) GTCTGC/GGCTCT 2 -- int10--------
    rs71277871,2
    C,F--119980287(+) GTTTCG/CGTGTT 2 -- int11Minor allele frequency- C:0.50WA 2
    rs28475001,2
    C,A--119980324(+) AGCTCG/ATCCCA 2 -- int14Minor allele frequency- A:0.17NA WA EA 360
    rs575725171,2
    C,F--119980388(+) TCCTAT/CGGGAC 2 -- int13Minor allele frequency- C:0.06WA CSA 121
    rs1154422421,2
    F--119980605(+) TTTGAT/GGAAGG 2 -- int11Minor allele frequency- G:0.04WA 118
    rs586738751,2
    C,F--119980621(+) TGGAGA/GATGGG 2 -- int13Minor allele frequency- G:0.06WA CSA 121
    rs1891380041,2
    --119980657(+) GCATGC/TGATTA 2 -- int10--------
    rs1505915911,2
    --119980843(+) TTACAA/GTGGTG 2 -- int10--------
    rs1395977211,2
    --119980846(+) CAATGA/GTGCTG 2 -- int10--------
    rs1130017391,2
    F--119980903(+) GGAGGG/AGCATG 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs1460497581,2
    --119980930(+) GGAAGC/TGGACT 2 -- int10--------
    rs1400160261,2
    --119980955(+) AGTGTC/TTGTTT 2 -- int10--------
    rs1437258381,2
    --119981257(+) GCAGTA/CTCTGA 2 -- int10--------
    rs1468141611,2
    C--119981327(+) ATCTGC/TGTTAG 2 -- int10--------
    rs112177731,2
    C--119981353(+) AGGGGA/GGATAG 2 -- int13Minor allele frequency- G:0.35NA EA 124
    rs1817121291,2
    --119981378(+) GAGAGA/GGGAGC 2 -- int10--------
    rs1149221671,2
    F--119981381(+) AGGGGA/TGCCCG 2 -- int11Minor allele frequency- T:0.03WA 118
    rs22525201,2
    C,F,A,H--119981473(+) TATTCT/ATGCAT 2 -- int110Minor allele frequency- A:0.46NA WA EA 376
    rs1489910841,2
    --119981549(+) CTAAAC/GGCTGT 2 -- int10--------
    rs1429011471,2
    --119981569(+) GGGGAA/GGGGGT 2 -- int10--------
    rs28475011,2
    C,F--119981612(+) GTGACC/TGACCA 2 -- int15Minor allele frequency- T:0.26NA CSA WA EA 362
    rs1511166031,2
    --119981631(+) AGTGTA/GGATTT 2 -- int10--------
    rs1850913661,2
    --119981754(+) CTGGGA/GTATTC 2 -- int10--------
    rs602381391,2
    C,F--119981840(+) TCGGCT/CGGAGC 2 -- int11Minor allele frequency- C:0.34EA 120
    rs1410814361,2
    --119981841(+) CGGCCA/GGAGCC 2 -- int10--------
    rs1159176271,2
    C,F--119981842(+) GGCCGA/GAGCCA 2 -- int10--------
    rs1820727461,2
    --119981897(+) TCTTTC/TCCTGG 2 -- int10--------
    rs585947711,2
    C,F--119981921(+) CCTTTT/CTCCTC 2 -- int14Minor allele frequency- C:0.09WA CSA 124
    rs1386850341,2
    --119982076(+) TTAAAC/GTGCTG 2 -- int10--------
    rs2001336451,2
    --119982091(+) GAGAA-/GGGGGG 2 -- int10--------
    rs124176501,2
    C,F,H--119982295(+) ATGTTC/TAATTT 2 -- int11Minor allele frequency- T:0.00NA 2
    rs1880290861,2
    --119982360(+) AGGGGC/TCTGGT 2 -- int10--------
    rs1812424871,2
    --119982444(+) GAGAAG/TGTAAG 2 -- int10--------
    rs1411239911,2
    --119982566(+) AGAAAA/GGTGAG 2 -- int10--------
    rs1469682511,2
    C--119982664(+) TAATTC/GTTTCA 2 -- int10--------
    rs1856023311,2
    --119982705(+) CCCAAA/CGGAAA 2 -- int10--------
    rs1900161801,2
    C--119982833(+) GCACCA/GGGGAA 2 -- int10--------
    rs1838445051,2
    --119982879(+) GGGAGA/GAGGGG 2 -- int10--------
    rs792262691,2
    C,F--119982929(+) TGTTCG/AGGAAT 2 -- int11Minor allele frequency- A:0.03NA 120
    rs777340701,2
    F--119982959(+) TGGTTA/GTTGTA 2 -- int10--------
    rs1495109441,2
    C--119983042(+) AAATCA/TGTTGT 2 -- int11Minor allele frequency- T:0.00EU 1193
    rs2013015381,2
    --119983069(+) TCAAGA/TTGAGT 4 M L mis10--------
    rs2010202921,2
    C--119983087(+) TAGCCA/GATTCC 4 N D mis10--------
    rs1505620131,2
    C,F--119983095(+) TCCACG/AGATGC 4 /T syn11Minor allele frequency- A:0.00NA 4552
    rs2009085651,2
    C--119983149(+) TTCTCG/AGGGAT 2 -- int11Minor allele frequency- A:0.00EU 1081
    rs1923300111,2
    C--119983154(+) GGGGAC/TGGAGG 2 -- int10--------
    rs1440078641,2
    C--119983159(+) TGGAGG/TGGGTG 2 -- int10--------
    rs71148511,2
    C,F--119983164(+) GGGGTG/CGGGGG 2 -- int1 trp32Minor allele frequency- C:0.50WA CSA 4
    rs2010935931,2
    C--119983164(+) GGGGT-/GGGGGG 2 -- int10--------
    rs735762761,2
    C,F--119983238(+) AGACCC/TCAAAG 2 -- int15Minor allele frequency- T:0.10NA WA EA 362
    rs1162710771,2
    C,F--119983276(+) CTGAGG/AACATG 2 -- int11Minor allele frequency- A:0.22WA 118
    rs1181254681,2
    F--119983297(+) CTGGAG/ACCTTT 2 -- int11Minor allele frequency- A:0.02NA 120
    rs765035741,2
    F--119983406(+) AGCAGC/GTGTGT 2 -- int11Minor allele frequency- G:0.01NA 120
    rs1836503311,2
    --119983474(+) CTTTTA/CGCCCC 2 -- int10--------
    rs1879569881,2
    --119983643(+) TAGTCC/TCAGCT 2 -- int10--------
    rs1912929221,2
    C--119983719(+) AAGCTG/TAGAGG 2 -- int10--------
    rs122765441,2
    C,F,H--119983854(+) CCAAAA/TAACTT 2 -- int121Minor allele frequency- N:0.00NS EA NA WA CSA 1398
    rs1418868871,2
    --119983980(+) TAGAGC/GAGTGT 2 -- int10--------
    rs1822423931,2
    --119984144(+) TCAAAC/GTACAA 2 -- int10--------
    rs1872843501,2
    --119984219(+) ACTCAC/TGTTTC 2 -- int10--------
    rs1917787521,2
    --119984227(+) TTCAAC/TAGATT 2 -- int10--------
    rs1854598031,2
    --119984400(+) GAAAAA/GCCAGC 2 -- int10--------
    rs28475021,2
    C,F,A,H--119984401(+) AAAAAT/CCAGCC 2 -- int126Minor allele frequency- C:0.39NS EA NA WA CSA 2371
    rs1898393011,2
    --119984522(+) GAGAGC/TGTCCA 2 -- int10--------
    rs1150396051,2
    C,F--119984523(+) AGAGCG/ATCCAC 2 -- int11Minor allele frequency- A:0.01WA 118
    rs1932720401,2
    --119984753(+) GGTTAA/GGAGAG 2 -- int10--------
    rs1854139351,2
    --119985126(+) CTGAGA/TACTTC 2 -- int10--------
    rs1892542281,2
    --119985297(+) GCTCCC/TGGCTG 2 -- int10--------
    rs125743741,2
    C,H--119985298(+) CTCCCG/AGCTGG 2 -- int14Minor allele frequency- A:0.33NA EA 244
    rs1158951311,2
    C,F--119985383(+) GTAACC/TAAACT 2 -- int11Minor allele frequency- T:0.04WA 118
    rs1809397711,2
    --119985400(+) AAAGTA/CGTTCT 2 -- int10--------
    rs1462658531,2
    --119985450(+) CACAAA/TGGTTA 2 -- int10--------
    rs1400472731,2
    --119985473(+) AATGGC/TTTCCT 2 -- int10--------
    rs1850618281,2
    --119985748(+) TGGCCA/GGGGGC 2 -- int10--------
    rs618982981,2
    C--119985751(+) CCGGGG/TGCACA 2 -- int13Minor allele frequency- T:0.34NA EA 242
    rs1161804221,2
    F--119985755(+) GGGCAC/TATGTT 2 -- int11Minor allele frequency- T:0.07WA 118
    rs1116817061,2
    F--119985874(+) CCTGTC/TCAGTA 2 -- int11Minor allele frequency- T:0.50CSA 2
    rs1887022381,2
    C--119986100(+) TACAGA/GCATGA 2 -- int10--------
    rs1152638321,2
    F--119986117(+) GCACCG/AGGACT 2 -- int11Minor allele frequency- A:0.03WA 118
    rs1811256711,2
    --119986173(+) TATGTA/GGTTGA 2 -- int10--------
    rs1463348891,2
    --119986177(+) TGGTTA/GATGAG 2 -- int10--------
    rs1166657701,2
    C,F--119986212(+) AAGCCC/TCCAGG 2 -- int11Minor allele frequency- T:0.04WA 118
    rs1392800421,2
    C--119986291(+) ATTGCC/TTCAAT 2 -- int10--------
    rs607580801,2
    C--119986338(+) AGGGAG/AAGATC 2 -- int13Minor allele frequency- A:0.34NA EA 242
    rs582548021,2
    C--119986426(+) ATAAGG/TCTATG 2 -- int13Minor allele frequency- T:0.34NA EA 242
    rs1500405971,2
    --119986443(+) AGACAC/TGATTA 2 -- int10--------
    rs1159845811,2
    C,F--119986479(+) CATAGC/TTCAGA 2 -- int11Minor allele frequency- T:0.24WA 118
    rs1453728961,2
    --119986864(+) CAGCTC/GTCTTC 2 -- int10--------
    rs1869821431,2
    --119987153(+) GAGAAA/GGAACC 2 -- int10--------
    rs112177751,2
    C,F,H--119987226(+) GTGACT/CTTCTA 2 -- int114Minor allele frequency- C:0.25NS EA NA 1750
    rs1914707881,2
    --119987239(+) TAAAGA/GTGGTG 2 -- int10--------
    rs1841128371,2
    --119987275(+) AGAACC/GAGGGA 2 -- int10--------
    rs1865486871,2
    --119987313(+) CTGGGC/TGCGGT 2 -- int10--------
    rs1909512191,2
    --119987314(+) TGGGCA/GCGGTG 2 -- int10--------
    rs1824897891,2
    --119987862(+) ATTACA/TTGTGT 2 -- int10--------
    rs1147318671,2
    F--119987893(+) CAACCA/GTCTCT 2 -- int11Minor allele frequency- G:0.02WA 118
    rs1867652101,2
    --119987925(+) CTGTGC/TGTGCG 2 -- int10--------
    rs1422961571,2
    C--119987931(+) GTGCG-/CACACAC 2 -- int10--------
    rs1929365521,2
    C--119987932(+) TGCGCA/GCACAC 2 -- int10--------
    rs1827967691,2
    --119988080(+) TTCATC/TGTAAT 2 -- int10--------
    rs1887102681,2
    --119988127(+) GTGGGA/CTAGGT 2 -- int10--------
    rs1491862351,2
    --119988143(+) CTAGGA/TTCTGC 2 -- int10--------
    rs1929665511,2
    --119988244(+) TCCTGC/TTATGA 2 -- int10--------
    rs1851894171,2
    --119988264(+) AGGACA/GTCTTG 2 -- int10--------
    rs1449745491,2
    --119988296(+) GGAGAC/TATTTC 2 -- int10--------
    rs118274711,2
    C,F,A,H--119988297(+) GAGACA/GTTTCA 2 -- int122Minor allele frequency- G:0.24NS EA NA WA 2588
    rs1879352241,2
    --119988388(+) CCCCAC/TGTTTT 2 -- int10--------
    rs1126672431,2
    C,F--119988530(+) CCTCCC/TGAATA 2 -- int12Minor allele frequency- T:0.50NA WA 4
    rs1142218241,2
    F--119988741(+) CAGTGC/TCTGGA 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1113855421,2
    C,F--119988778(+) CCCTCA/CTGCTG 2 -- int12Minor allele frequency- C:0.03CSA WA 120
    rs2001048061,2
    C--119988817(+) CTTTTC/TTNNNN 2 -- int10--------
    rs2018405861,2
    C--119988820(+) TTTCT-/C/TC  
            
    TTTTT
    2 -- int10--------
    rs71097371,2
    C,F--119988975(+) caccaC/Tgcctg 2 -- int11Minor allele frequency- T:0.50WA 2
    rs1133488461,2
    C--119989047(+) CTCCTG/AACCTC 2 -- int11Minor allele frequency- A:0.50NA 2
    rs1924515401,2
    --119989108(+) GCCTCC/TGCACC 2 -- int10--------
    rs116032781,2
    C,H--119989192(+) AAGTAC/GTGATT 2 -- int10--------
    rs1407590191,2
    --119989408(+) AGCAGA/GGGTGG 2 -- int10--------
    rs1836461011,2
    --119989423(+) ATTGTA/GTGGTT 2 -- int10--------
    rs1501100911,2
    --119989439(+) GAGCCA/GTGAGG 2 -- int10--------
    rs1879639721,2
    --119989603(+) GCCTGC/GTGTGG 2 -- int10--------
    rs1168630151,2
    C,F--119989739(+) GACATG/ACACCC 2 -- int11Minor allele frequency- A:0.02NA 120
    rs1386049781,2
    --119989748(+) CCAGAC/TCTACT 2 -- int10--------
    rs1814790871,2
    --119989777(+) CTTGCA/GCTTAC 2 -- int10--------
    rs802542031,2
    C,F--119989788(+) CATGCG/CTACTC 2 -- int14Minor allele frequency- C:0.17WA NA EA 242
    rs1417413301,2
    --119990039(+) GCTAAG/TTTTTG 2 -- int10--------
    rs1846121901,2
    --119990086(+) AGGCTA/GGTCTC 2 -- int10--------
    rs595650181,2
    C--119990205(+) TGTCCG/ATAGCT 2 -- int13Minor allele frequency- A:0.28NA EA 242
    rs1897874771,2
    --119990323(+) AGGACA/GTAAGA 2 -- int10--------
    rs1818452851,2
    --119990427(+) CCTCCA/GTGAGC 2 -- int10--------
    rs1380875391,2
    C--119990529(+) GAGACA/CCAGCA 2 -- int10--------
    rs1136219061,2
    F--119990748(+) CTCAGC/AAACGA 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs1860886131,2
    --119990804(+) AGGAAA/GAATTT 2 -- int10--------
    rs27158881,2
    C,F,A,H--119990856(+) TGAAGA/GGCAGC 2 -- int113Minor allele frequency- G:0.32NA WA CSA EA 379
    rs1912025591,2
    --119990882(+) TGACAA/TGCAGC 2 -- int10--------
    rs1818064451,2
    --119990937(+) CAGACA/GTACAC 2 -- int10--------
    rs1485046111,2
    --119990961(+) GTTGGA/GGGTGC 2 -- int10--------
    rs1853370541,2
    --119991020(+) ATTGGC/GTGCTT 2 -- int10--------
    rs1419083171,2
    --119991065(+) AGATGA/GCAAGT 2 -- int10--------
    rs754811201,2
    C--119991115(+) CACTT-/CCCCCC 2 -- int10--------
    rs1906351581,2
    --119991338(+) TGGGGC/GTCTGG 2 -- int10--------
    rs1827611811,2
    --119991376(+) GCCCTC/TATAAG 2 -- int10--------
    rs1506406691,2
    --119991657(+) ATCTCA/CTACCA 2 -- int10--------
    rs1880837511,2
    --119991721(+) GGCCTC/TGTGGT 2 -- int10--------
    rs1914027571,2
    --119991722(+) GCCTCA/GTGGTC 2 -- int10--------
    rs1409645451,2
    C--119991783(+) AGCCCA/CGCCAG 2 -- int10--------
    rs1447830011,2
    --119991815(+) CCTGGC/GTGTGC 2 -- int10--------
    rs1830235961,2
    C--119991828(+) AGTCCA/TGGTTT 2 -- int10--------
    rs1123469421,2
    C,F--119991846(+) AGGTGC/TGGGCA 2 -- int11Minor allele frequency- T:0.50CSA 2
    rs799887611,2
    C,F--119991920(+) AGGGGG/ACTTGC 2 -- int13Minor allele frequency- A:0.08WA NA EA 358
    rs1872291721,2
    --119991959(+) AGGAAC/TGAAAA 2 -- int10--------
    rs1401617221,2
    --119992012(+) ACTGGG/TTGGTT 2 -- int10--------
    rs1925032561,2
    --119992040(+) TCGGCA/GCCCAA 2 -- int10--------
    rs791625131,2
    C,F--119992070(+) TCCATA/GCTGCA 2 -- int11Minor allele frequency- G:0.01NA 120
    rs1845764161,2
    --119992113(+) GTTGGG/TGTGGG 2 -- int10--------
    rs1450458151,2
    --119992151(+) ATGAGG/TATGAT 2 -- int10--------
    rs27158811,2
    C,F,O,A,H--119992180(-) TCCACA/GCTTCC 2 -- int132Minor allele frequency- G:0.41NA NS EA WA CSA 3010
    rs79446031,2
    C,A--119992216(+) ATGTCA/GGCTCC 2 -- int10--------
    rs1122027851,2
    C,F--119992352(+) GCCTCA/GCAGGA 2 -- int13Minor allele frequency- G:0.03CSA WA 121
    rs1867305711,2
    --119992362(+) AGAGCC/TGGCTG 2 -- int10--------
    rs1490270181,2
    --119992434(+) AGTTCA/GTGGGA 2 -- int10--------
    rs1924299921,2
    --119992531(+) GAGACA/TGGGGA 2 -- int10--------
    rs1844016891,2
    --119992533(+) GACTGA/GGGAAT 2 -- int10--------
    rs750729971,2
    C,F--119992586(+) GATGGC/ATTCTG 2 -- int11Minor allele frequency- A:0.42EA 120
    rs1431035151,2
    --119992666(+) TAAGAC/TGAAGG 2 -- int10--------
    rs1161200241,2
    F--119992676(+) GGTCTG/CAATCT 2 -- int11Minor allele frequency- C:0.01WA 118
    rs124180401,2
    C,F,H--119992685(+) CTGAGG/AGTCTC 2 -- int19Minor allele frequency- A:0.13NS EA NA WA 780
    rs1511663621,2
    --119992706(+) TCCAGC/TTCTGA 2 -- int10--------
    rs1897492121,2
    --119992807(+) TAAGTC/GTCTCT 2 -- int10--------
    rs1813329051,2
    --119992870(+) CTATCC/TGCTCA 2 -- int10--------
    rs1156106351,2
    F--119992930(+) CTGCTG/ATGAGG 2 -- int11Minor allele frequency- A:0.02WA 118
    rs1403452751,2
    --119992974(+) AGAGCA/GCCTGC 2 -- int10--------
    rs1845380011,2
    --119993098(+) TCCAGA/GAAGAC 2 -- int10--------
    rs1888996321,2
    --119993137(+) CACTGA/TCGTGT 2 -- int10--------
    rs1819587371,2
    --119993400(+) TAGATA/GTTGTA 2 -- int10--------
    rs79453411,2
    C,F,H--119993438(+) TCCCAT/GAGAGT 2 -- int17Minor allele frequency- G:0.05NS EA WA CSA 508
    rs1176015111,2
    C,F--119993639(+) ACTCAT/CAGGGT 2 -- int11Minor allele frequency- C:0.03NA 120
    rs1453991731,2
    --119993703(+) GTGCGC/TAGTAA 2 -- int10--------
    rs735762911,2
    C,F--119993758(+) AACAGT/AGTTCT 2 --