Aliases for POU2F3 Gene
Aliases for POU2F3 Gene
External Ids for POU2F3 Gene
- HGNC: 19864
- Entrez Gene: 25833
- Ensembl: ENSG00000137709
- OMIM: 607394
- UniProtKB: Q9UKI9
Previous GeneCards Identifiers for POU2F3 Gene
- GC11P122110
- GC11P121622
- GC11P120144
- GC11P119648
- GC11P119616
- GC11P116050
Summaries for POU2F3 Gene
-
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for POU2F3 Gene
POU2F3 (POU Class 2 Homeobox 3) is a Protein Coding gene. Diseases associated with POU2F3 include Blood Coagulation Disease and Hemorrhagic Disease. Among its related pathways are Influenza A. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is POU2F1.
UniProtKB/Swiss-Prot for POU2F3 Gene
-
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POU2F3 Gene
Genomics for POU2F3 Gene
Regulatory Elements for POU2F3 Gene
Enhancers for POU2F3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH11G120207 | 1.7 | FANTOM5 ENCODE dbSUPER | 29.1 | -25.5 | -25472 | 6.9 | CREB3L1 ARID4B SIN3A DMAP1 ZNF48 YY1 GLIS2 FOS SP3 SP5 | POU2F3 TRIM29 LOC729173 OAF ARHGEF12 GRIK4 |
| GH11G120217 | 1 | ENCODE dbSUPER | 30.8 | -16.7 | -16720 | 4.8 | ELF3 SOX13 DRAP1 SAP130 ARID4B RAD21 ZIC2 RARA YY1 ZNF664 | POU2F3 TRIM29 LOC729173 TMEM136 OAF |
| GH11G120316 | 1.4 | Ensembl ENCODE dbSUPER | 16.5 | +80.5 | 80505 | 1.9 | NFIB SIN3A DMAP1 THRB RARA ZNF335 EGR1 FOS RELB IKZF2 | POU2F3 TMEM136 GC11P120299 |
| GH11G120181 | 1.5 | Ensembl ENCODE dbSUPER | 12.1 | -50.3 | -50297 | 9.0 | HDGF ZFP64 WRNIP1 ARID4B DMAP1 ZNF48 YY1 ZNF143 FOS ZNF263 | OAF POU2F3 TRIM29 LOC729173 LOC105369530 |
| GH11G120280 | 0.9 | ENCODE | 16.9 | +44.5 | 44455 | 2.1 | HDAC1 PKNOX1 CBX3 RB1 TBL1XR1 ARNT TCF12 GATA2 SMARCA5 ZBTB2 | POU2F3 TMEM136 TRIM29 ARHGEF12 LOC105369520 GC11P120275 LOC105369531 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around POU2F3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for POU2F3 Gene
- Chromosome:
- 11
- Start:
- 120,236,640 bp from pter
- End:
- 120,319,945 bp from pter
- Size:
- 83,306 bases
- Orientation:
- Plus strand
Genomic View for POU2F3 Gene
Genes around POU2F3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.3 by Ensembl
- 11q23.3 by Entrez Gene
- 11q23.3 by HGNC
POU2F3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for POU2F3 Gene
Proteins for POU2F3 Gene
-
Protein details for POU2F3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UKI9-PO2F3_HUMAN
- Recommended name:
- POU domain, class 2, transcription factor 3
- Protein Accession:
- Q9UKI9
- A8K7H8
- B4DY07
- F5GWW6
- Q3MIY3
- Q9UKR7
- Q9Y504
Protein attributes for POU2F3 Gene
- Size:
- 436 amino acids
- Molecular mass:
- 47432 Da
- Quaternary structure:
- No Data Available
Protein Expression for POU2F3 Gene
Post-translational modifications for POU2F3 Gene
Other Protein References for POU2F3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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- antibodies-online Antibodies for POU2F3: See all 28
- GeneTex POU2F3 antibody for POU2F3
-
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-
Santa Cruz Biotechnology (SCBT) Antibodies for POU2F3
Protein Products
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OriGene Purified Proteins for POU2F3
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- antibodies-online Proteins for POU2F3: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for POU2F3
Assay Products
- antibodies-online Kits for POU2F3: See all 2
No data available for DME Specific Peptides for POU2F3 Gene
Domains & Families for POU2F3 Gene
Gene Families for POU2F3 Gene
Protein Domains for POU2F3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for POU2F3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UKI9UniProtKB/Swiss-Prot:
PO2F3_HUMAN :- Belongs to the POU transcription factor family. Class-2 subfamily.
- Family:
-
- Belongs to the POU transcription factor family. Class-2 subfamily.
Function for POU2F3 Gene
Molecular function for POU2F3 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IMP | 12624109 |
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | IMP | 12624109 |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 12624109 |
Phenotypes for POU2F3 Gene
- MGI mutant phenotypes for POU2F3:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for POU2F3:
-
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased ionizing radiation sensitivity
- Decreased shRNA abundance (Z-score < -2)
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Decreased viability after Maraba virus infection
Animal Models for POU2F3 Gene
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for POU2F3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for POU2F3 gene
- Search ViGene Biosciences for POU2F3
CRISPR Products
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-
Santa Cruz Biotechnology (SCBT) CRISPR for POU2F3
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miRNA for POU2F3 Gene
- miRTarBase miRNAs that target POU2F3
-
- hsa-mir-335-5p (MIRT016830)
- hsa-mir-26b-5p (MIRT028932)
- hsa-mir-3620-5p (MIRT622639)
- hsa-mir-1587 (MIRT622640)
- hsa-mir-7703 (MIRT622641)
- hsa-mir-6720-5p (MIRT622642)
- hsa-mir-6512-3p (MIRT622643)
- hsa-mir-4741 (MIRT622644)
- hsa-mir-4675 (MIRT622645)
- hsa-mir-762 (MIRT622646)
- hsa-mir-5001-5p (MIRT622647)
- hsa-mir-4498 (MIRT622648)
- hsa-mir-4492 (MIRT622649)
- hsa-mir-6829-5p (MIRT622650)
- hsa-mir-4656 (MIRT622651)
- hsa-mir-4430 (MIRT622652)
- hsa-mir-3652 (MIRT622653)
- hsa-mir-6081 (MIRT622654)
- hsa-mir-3135b (MIRT622655)
- hsa-mir-661 (MIRT622656)
- hsa-mir-378g (MIRT622657)
- hsa-mir-766-3p (MIRT622658)
- hsa-mir-939-3p (MIRT622659)
- hsa-mir-6849-3p (MIRT622660)
- hsa-mir-508-5p (MIRT622661)
- hsa-mir-3679-3p (MIRT649933)
- hsa-mir-5681b (MIRT649934)
- hsa-mir-6832-3p (MIRT649935)
- hsa-mir-4252 (MIRT666861)
- hsa-mir-4793-3p (MIRT666862)
- hsa-mir-1273g-3p (MIRT666863)
- hsa-mir-7977 (MIRT672454)
- hsa-mir-24-3p (MIRT672455)
- hsa-mir-4284 (MIRT672456)
- hsa-mir-4755-3p (MIRT672457)
- hsa-mir-342-3p (MIRT672458)
- hsa-mir-1972 (MIRT672459)
- hsa-mir-5685 (MIRT672460)
- hsa-mir-4690-3p (MIRT672461)
- hsa-mir-1228-3p (MIRT672462)
- hsa-mir-5694 (MIRT696230)
miRNA Products
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Inhibitory RNA Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for POU2F3
-
ViGene Biosciences adenoviral particle packaged cDNA for POU2F3 gene
-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for POU2F3 Gene
Localization for POU2F3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for POU2F3 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| extracellular | 2 |
| plasma membrane | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,IEA | 9242494 |
Pathways & Interactions for POU2F3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Influenza A | ||
Pathways by source for POU2F3 Gene
1 KEGG pathway for POU2F3 Gene
Interacting Proteins for POU2F3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | TAS | 10473598 |
| GO:0006366 | transcription from RNA polymerase II promoter | IEA | -- |
| GO:0008544 | epidermis development | TAS | 10473598 |
No data available for SIGNOR curated interactions for POU2F3 Gene
Transcripts for POU2F3 Gene
mRNA/cDNA for POU2F3 Gene
- (8) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (84) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for POU2F3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for POU2F3
-
Santa Cruz Biotechnology (SCBT) CRISPR for POU2F3
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miRNA Products
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Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for POU2F3 gene
Clone Products
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- VectorBuilder custom plasmid, inducible vectors for POU2F3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for POU2F3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for POU2F3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Inner Cell Mass (Early Embryonic Tissues)
-
Colon (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for POU2F3 Gene
This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x21.9) and Skin - Not Sun Exposed (Suprapubic) (x21.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for POU2F3 Gene
NURSA nuclear receptor signaling pathways regulating expression of POU2F3 Gene:
POU2F3SOURCE GeneReport for Unigene cluster for POU2F3 Gene:
Hs.227115mRNA Expression by UniProt/SwissProt for POU2F3 Gene:
Q9UKI9-PO2F3_HUMAN
Tissue specificity:
Specifically expressed in epidermis and cultured keratinocytes.
Evidence on tissue expression from TISSUES for POU2F3 Gene
- Nervous system(4.3)
- Intestine(4.2)
- Blood(2.7)
- Skin(2.5)
Primer Products
-
OriGene qPCR primer pairs for POU2F3
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for POU2F3 Gene
Orthologs for POU2F3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | POU2F3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | POU2F3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | POU2F3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Pou2f3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Pou2f3 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | POU2F3 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | POU2F3 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | POU2F3 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | POU2F3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | pou2f3 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | pou2f3 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | pdm2 35 |
|
ManyToMany | |
| nub 35 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | ceh-18 35 |
|
OneToMany |
- Species where no ortholog for POU2F3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for POU2F3 Gene
Paralogs for POU2F3 Gene
(13) SIMAP similar genes for POU2F3 Gene using alignment to 3 proteins:
Variants for POU2F3 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000008682 | -- | 120,276,517(+) | AGGAT(C/G)CAGCC | intron-variant | |
| rs1000022772 | -- | 120,304,525(+) | AGTTC(C/T)ATGAA | intron-variant | |
| rs1000042506 | -- | 120,318,708(+) | TTTCA(C/G)AGAAA | utr-variant-3-prime | |
| rs1000075814 | -- | 120,254,284(+) | AGTCT(C/G)TCCCA | intron-variant | |
| rs1000109236 | -- | 120,291,601(+) | AGTGA(A/G)GATTG | intron-variant, nc-transcript-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2550380 | CNV | insertion | 19546169 |
| esv2612935 | CNV | insertion | 19546169 |
| esv3379673 | CNV | duplication | 20981092 |
| nsv518 | CNV | insertion | 18451855 |
| nsv518464 | CNV | loss | 19592680 |
| nsv522706 | CNV | loss | 19592680 |
Residual Variation Intolerance Score:
50.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.40;
85.54% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for POU2F3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- POU2F3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POU2F3 Gene
Disorders for POU2F3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| blood coagulation disease |
|
|
| hemorrhagic disease |
|
|
Search POU2F3 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for POU2F3
No data available for UniProtKB/Swiss-Prot and Genatlas for POU2F3 Gene
Publications for POU2F3 Gene
- Characterization of the regulatory domains of the human skn-1a/Epoc- 1/Oct-11 POU transcription factor. (PMID: 10473598) Hildesheim J. … Vogel J.C. (J. Biol. Chem. 1999) 2 3 4 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation. (PMID: 17195013) Beck I.M. … Sedlacek R. (J. Invest. Dermatol. 2007) 3 22 64
- The transcription factor PLA-1/SKN-1A is expressed in human placenta and regulates the placental lactogen-3 gene expression. (PMID: 16005513) JimAcnez-Mateo O. … Castrillo J.L. (Placenta 2006) 3 22 64
- Aberrant promoter methylation and silencing of the POU2F3 gene in cervical cancer. (PMID: 16607278) Zhang Z. … Rader J.S. (Oncogene 2006) 3 22 64
Products for POU2F3 Gene
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- VectorBuilder custom plasmid, inducible vectors for POU2F3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for POU2F3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for POU2F3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer