Aliases for POU2F2 Gene
Aliases for POU2F2 Gene
External Ids for POU2F2 Gene
- HGNC: 9213
- Entrez Gene: 5452
- Ensembl: ENSG00000028277
- OMIM: 164176
- UniProtKB: P09086
Previous HGNC Symbols for POU2F2 Gene
- OTF2
Previous GeneCards Identifiers for POU2F2 Gene
- GC19M043234
- GC19M042986
- GC19M047271
- GC19M047286
- GC19M042592
- GC19M039023
Summaries for POU2F2 Gene
-
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for POU2F2 Gene
POU2F2 (POU Class 2 Homeobox 2) is a Protein Coding gene. Diseases associated with POU2F2 include T-Cell/Histiocyte Rich Large B Cell Lymphoma and Papilloma. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Ectoderm Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein domain specific binding. An important paralog of this gene is POU2F1.
UniProtKB/Swiss-Prot for POU2F2 Gene
-
Transcription factor that specifically binds to the octamer motif (5-ATTTGCAT-3). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POU2F2 Gene
Genomics for POU2F2 Gene
Regulatory Elements for POU2F2 Gene
Enhancers for POU2F2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around POU2F2 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the POU2F2 gene promoter:
Regulatory Element Products
Genomic Location for POU2F2 Gene
- Chromosome:
- 19
- Start:
- 42,086,110 bp from pter
- End:
- 42,196,585 bp from pter
- Size:
- 110,476 bases
- Orientation:
- Minus strand
Genomic View for POU2F2 Gene
Genes around POU2F2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.2 by Ensembl
- 19q13.2 by Entrez Gene
- 19q13.2 by HGNC
POU2F2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for POU2F2 Gene
Proteins for POU2F2 Gene
-
Protein details for POU2F2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P09086-PO2F2_HUMAN
- Recommended name:
- POU domain, class 2, transcription factor 2
- Protein Accession:
- P09086
- Q16648
- Q7M4M8
- Q9BRS4
Protein attributes for POU2F2 Gene
- Size:
- 479 amino acids
- Molecular mass:
- 51209 Da
- Quaternary structure:
-
- Interacts with NR3C1, AR and PGR.
- SequenceCaution:
-
- Sequence=CAA32039.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for POU2F2 Gene
Post-translational modifications for POU2F2 Gene
Other Protein References for POU2F2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001193954.1
- NP_001193955.1
- NP_001234923.1
- NP_002689.1
- XP_005259067.1
- XP_011525342.1
- XP_011525343.1
- XP_011525344.1
- XP_011525345.2
- XP_016882373.1
- XP_016882374.1
- XP_016882375.1
- XP_016882376.1
- XP_016882377.1
- XP_016882378.1
- XP_016882379.1
- XP_016882380.1
- XP_016882381.1
- XP_016882382.1
- XP_016882383.1
- XP_016882384.1
- XP_016882385.1
Antibody Products
- Novus Biologicals Antibodies for POU2F2
-
Abcam antibodies for POU2F2
-
Cloud-Clone Corp. Antibodies for POU2F2
- Invitrogen Antibodies for POU2F2
- GeneTex POU2F2 antibody for POU2F2
-
Santa Cruz Biotechnology (SCBT) Antibodies for POU2F2
Protein Products
-
OriGene Purified Proteins for POU2F2
- Search Origene for MassSpec and Protein Over-expression Lysates for POU2F2
- Origene Custom Protein Services for POU2F2
-
Cloud-Clone Corp. Proteins for POU2F2
- Search GeneTex for Proteins for POU2F2
-
Abcam proteins for POU2F2
No data available for DME Specific Peptides for POU2F2 Gene
Domains & Families for POU2F2 Gene
Gene Families for POU2F2 Gene
Protein Domains for POU2F2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for POU2F2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P09086UniProtKB/Swiss-Prot:
PO2F2_HUMAN :- Belongs to the POU transcription factor family. Class-2 subfamily.
- Family:
-
- Belongs to the POU transcription factor family. Class-2 subfamily.
Function for POU2F2 Gene
Molecular function for POU2F2 Gene
- GENATLAS Biochemistry:
- POU domain,class 2,transcription factor 2,expressed in the immune system,also involved in the control of the forebrain development and the cell-cell signaling process underlying the hypothalamic regulation of female puberty
- UniProtKB/Swiss-Prot Function:
- Transcription factor that specifically binds to the octamer motif (5-ATTTGCAT-3). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IEA | -- |
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | IEA,TAS | 9442393 |
| GO:0019904 | protein domain specific binding | IEA | -- |
Phenotypes for POU2F2 Gene
- MGI mutant phenotypes for POU2F2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for POU2F2:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Synthetic lethal with Ras
- Decreased shRNA abundance (Z-score < -2)
- Dynamic nuclei (hole, folded or small irregular)
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased shRNA abundance (Z-score > 2)
- Effect on mitosis
- Decreased Salmonella proliferation
- Decreased interferon-beta reporter expression
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for POU2F2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for POU2F2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for POU2F2 gene
- Search ViGene Biosciences for POU2F2
CRISPR Products
-
OriGene CRISPR knockouts for POU2F2
-
Santa Cruz Biotechnology (SCBT) CRISPR for POU2F2
- GenScript: Design CRISPR guide RNA sequences for POU2F2
miRNA for POU2F2 Gene
- miRTarBase miRNAs that target POU2F2
-
- hsa-mir-9-5p (MIRT000639)
- hsa-mir-4768-5p (MIRT388051)
- hsa-mir-6809-3p (MIRT388055)
- hsa-mir-6833-3p (MIRT388056)
- hsa-mir-1277-5p (MIRT509443)
- hsa-mir-6083 (MIRT509444)
- hsa-mir-190a-3p (MIRT509445)
- hsa-mir-4307 (MIRT509446)
- hsa-mir-5011-5p (MIRT509447)
- hsa-mir-5006-3p (MIRT521790)
- hsa-mir-4755-5p (MIRT521791)
- hsa-mir-211-5p (MIRT521792)
- hsa-mir-204-5p (MIRT521793)
- hsa-mir-623 (MIRT521794)
- hsa-mir-6832-3p (MIRT521795)
- hsa-mir-410-3p (MIRT521796)
- hsa-mir-513c-3p (MIRT521797)
- hsa-mir-513a-3p (MIRT521798)
- hsa-mir-3606-3p (MIRT521799)
- hsa-mir-6755-5p (MIRT614838)
- hsa-mir-6841-5p (MIRT614839)
- hsa-mir-6512-5p (MIRT614840)
- hsa-mir-6768-3p (MIRT614841)
- hsa-mir-6888-3p (MIRT666864)
- hsa-mir-6794-3p (MIRT666865)
- hsa-mir-3120-5p (MIRT666866)
- hsa-mir-1304-3p (MIRT666867)
- hsa-mir-3162-3p (MIRT666868)
- hsa-mir-4639-3p (MIRT666869)
- hsa-mir-510-5p (MIRT666870)
- hsa-mir-10b-5p (MIRT666871)
- hsa-mir-10a-5p (MIRT666872)
- hsa-mir-504-5p (MIRT666873)
- hsa-mir-6839-3p (MIRT720155)
- hsa-mir-659-3p (MIRT720156)
- hsa-mir-29b-2-5p (MIRT720157)
- hsa-mir-4753-3p (MIRT720158)
- hsa-mir-130b-5p (MIRT720159)
Transcription Factor Targets for POU2F2 Gene
Targeted motifs for POU2F2 Gene
HOMER Transcription Factor Regulatory Elements motif POU2F2
- Consensus sequence: ATATGCAAAT Submotif: canonical Cell Type: Bcell GEO ID: GSE21512
miRNA Products
- Search ViGene Biosciences for POU2F2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for POU2F2
- Browse OriGene Inhibitory RNA Products For POU2F2
-
ViGene Biosciences ready-to-package AAV shRNAs for POU2F2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for POU2F2
- VectorBuilder custom plasmid, inducible vectors for POU2F2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for POU2F2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for POU2F2
-
ViGene Biosciences adenoviral particle packaged cDNA for POU2F2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for POU2F2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for POU2F2 gene
No data available for Enzyme Numbers (IUBMB) and Human Phenotype Ontology for POU2F2 Gene
Localization for POU2F2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for POU2F2 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 9242494 |
| GO:0005654 | nucleoplasm | IDA,TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | -- |
Pathways & Interactions for POU2F2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.48
|
|
| 2 | RNA polymerase II transcribes snRNA genes | ||
| 3 | Development_Glucocorticoid receptor signaling | ||
| 4 | B cell receptor signaling pathway (KEGG) | ||
| 5 | Ectoderm Differentiation | ||
Pathways by source for POU2F2 Gene
3 BioSystems pathways for POU2F2 Gene
2 Reactome pathways for POU2F2 Gene
1 GeneGo (Thomson Reuters) pathway for POU2F2 Gene
Interacting Proteins for POU2F2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002335 | mature B cell differentiation | IEA | -- |
| GO:0002380 | immunoglobulin secretion involved in immune response | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | 9442393 |
Drugs & Compounds for POU2F2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Dolutegravir | Approved | Pharma | Enzyme, inhibitor | 150 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for POU2F2 Gene
mRNA/cDNA for POU2F2 Gene
- (22) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (219) Selected AceView cDNA sequences:
- (20) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for POU2F2 Gene
- POU class 2 homeobox 2:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for POU2F2
-
Santa Cruz Biotechnology (SCBT) CRISPR for POU2F2
- GenScript: Design CRISPR guide RNA sequences for POU2F2
miRNA Products
- Search ViGene Biosciences for POU2F2
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for POU2F2
- Browse OriGene Inhibitory RNA Products For POU2F2
-
ViGene Biosciences ready-to-package AAV shRNAs for POU2F2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for POU2F2
- VectorBuilder custom plasmid, inducible vectors for POU2F2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for POU2F2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - |
| ExUns: | 19 |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: | |
| SP7: |
Expression for POU2F2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Juxtaglomerular Cells Afferent Arteriole
-
Smooth Muscle (Muscoskeletal System)
- Juxtaglomerular Cells Afferent Arteriole
mRNA differential expression in normal tissues according to GTEx for POU2F2 Gene
This gene is overexpressed in Whole Blood (x7.5) and Spleen (x5.3).
This gene is overexpressed in Peripheral blood mononuclear cells (30.6), Blymphocyte (21.6), and Monocytes (16.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for POU2F2 Gene
NURSA nuclear receptor signaling pathways regulating expression of POU2F2 Gene:
POU2F2SOURCE GeneReport for Unigene cluster for POU2F2 Gene:
Hs.147381mRNA Expression by UniProt/SwissProt for POU2F2 Gene:
P09086-PO2F2_HUMAN
Tissue specificity:
Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
Primer Products
-
OriGene qPCR primer pairs for POU2F2
No data available for Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for POU2F2 Gene
Orthologs for POU2F2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| platypus (Ornithorhynchus anatinus) |
Mammalia | POU2F2 35 |
|
OneToOne | |
| chimpanzee (Pan troglodytes) |
Mammalia | POU2F2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | POU2F2 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Pou2f2 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Pou2f2 34 |
|
||
| cow (Bos Taurus) |
Mammalia | POU2F2 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | POU2F2 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | pou2f2 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | pou2f2a 34 35 |
|
||
| pou2f2b 35 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | nub 36 35 |
|
||
| pdm2 36 35 |
|
||||
| worm (Caenorhabditis elegans) |
Secernentea | ceh-6 36 |
|
|
|
| ceh-18 35 |
|
OneToMany |
- Species where no ortholog for POU2F2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for POU2F2 Gene
Paralogs for POU2F2 Gene
(14) SIMAP similar genes for POU2F2 Gene using alignment to 12 proteins:
Variants for POU2F2 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000035858 | -- | 42,121,133(+) | TCTGA(C/T)TCAAC | intron-variant | |
| rs1000114525 | -- | 42,175,062(+) | TTCCC(A/G)CTAGG | intron-variant | |
| rs1000128321 | -- | 42,116,643(+) | CCTTC(C/G)CACAC | intron-variant | |
| rs1000153127 | -- | 42,110,609(+) | AACTG(A/T)ACAGG | intron-variant | |
| rs1000181565 | -- | 42,192,543(+) | GCATC(A/G)TATTT | intron-variant |
Residual Variation Intolerance Score:
30.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.32;
41.35% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for POU2F2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- POU2F2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POU2F2 Gene
Disorders for POU2F2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| t-cell/histiocyte rich large b cell lymphoma |
|
|
| papilloma |
|
|
Search POU2F2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for POU2F2
No data available for UniProtKB/Swiss-Prot and Genatlas for POU2F2 Gene
Publications for POU2F2 Gene
- Short introns interrupting the Oct-2 POU domain may prevent recombination between POU family genes without interfering with potential POU domain 'shuffling' in evolution. (PMID: 7888080) Matsuo K. … Schaffner W. (Biol. Chem. Hoppe-Seyler 1994) 3 4 22 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
- A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation. (PMID: 19270158) Theodorou E. … Snyder M. (Genes Dev. 2009) 3 22 64
- Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity. (PMID: 19625999) Filipski K.K. … Sparreboom A. (Clin. Pharmacol. Ther. 2009) 3 46 64
- Oct transcription factors mediate t(14;18) lymphoma cell survival by directly regulating bcl-2 expression. (PMID: 16186795) Heckman C.A. … Boxer L.M. (Oncogene 2006) 3 22 64
Products for POU2F2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for POU2F2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for POU2F2
- Search Origene for MassSpec and Protein Over-expression Lysates for POU2F2
- Origene Custom Protein Services for POU2F2
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for POU2F2
- Browse OriGene Inhibitory RNA Products For POU2F2
- OriGene qPCR primer pairs for POU2F2
- OriGene CRISPR knockouts for POU2F2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For POU2F2
- GenScript: Next-day shipping cDNA ORF clone for POU2F2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for POU2F2
- GenScript Custom Assay Services for POU2F2
- GenScript Custom overexpressing Cell Line Services for POU2F2
- GenScript: Design CRISPR guide RNA sequences for POU2F2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for POU2F2
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for POU2F2
- Novus Biologicals proteins and lysates for POU2F2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for POU2F2
- Abcam proteins for POU2F2
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Cloud-Clone Corp. Antibodies for POU2F2
- Cloud-Clone Corp. Proteins for POU2F2
- Browse Assay Kits at Cloud-Clone Corp.
- Invitrogen Antibodies for POU2F2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for POU2F2
- GeneTex POU2F2 antibody for POU2F2
- Search GeneTex for Proteins for POU2F2
- ViGene Biosciences adenoviral particle packaged cDNA for POU2F2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for POU2F2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for POU2F2 gene
- Search ViGene Biosciences for POU2F2
- Santa Cruz Biotechnology (SCBT) Antibodies for POU2F2
- Search Santa Cruz Biotechnology (SCBT) for POU2F2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for POU2F2
- Horizon Cell Lines for POU2F2
- Cyagen custom Knockout/knockin (KOKI) mouse models for POU2F2
- VectorBuilder custom plasmid, inducible vectors for POU2F2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for POU2F2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for POU2F2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer