Aliases for POU2AF1 Gene
External Ids for POU2AF1 Gene
Previous GeneCards Identifiers for POU2AF1 Gene
GeneCards Summary for POU2AF1 Gene
POU2AF1 (POU Class 2 Associating Factor 1) is a Protein Coding gene. Diseases associated with POU2AF1 include Primary Biliary Cirrhosis and Hodgkin Lymphoma. GO annotations related to this gene include transcription coactivator activity and transcription cofactor activity.
UniProtKB/Swiss-Prot for POU2AF1 Gene
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.