POU1F1 Gene

Aliases
for POU1F1 gene

Previous GC identifers: GC03M087883 GC03M090090 GC03M087188 GC03M087229 GC03M087391

Summaries
for POU1F1 gene

Genomic Views
for POU1F1 gene

RefSeq DNA sequence:

NC_000003.11  NC_018914.1  NT_022459.15  

SwitchGear Promoter luciferase reporter plasmid: POU1F1 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POU1F1

POU1F1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M087307:  view genomic region     (about GC identifiers)

Proteins
for POU1F1 gene

Explore the universe of human proteins at neXtProt for POU1F1: NX_P28069

Post-translational modifications:

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	Novus Biologicals POU1F1 Proteins Novus Biologicals POU1F1 Lysate
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	Uscn Proteins for POU1F1

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

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	ThermoFisher Antibodies for POU1F1

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	Uscn ELISAs and CLIAs for POU1F1

Protein Domains /
Families
for POU1F1 gene

ProtoNet protein and cluster: P28069

Function
for POU1F1 gene

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POU1F1
		1 QIAGEN miScript miRNA Assays for microRNA that regulate POU1F1:
		hsa-miR-4251
		SwitchGear 3'UTR luciferase reporter plasmid: POU1F1 3' UTR sequence

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		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POU1F1 (see all 7) OriGene shRNA RFP: POU1F1 OriGene siRNA: POU1F1
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Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for POU1F1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POU1F1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POU1F1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU1F1

Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10):    About this table

(inferred from 2 alleles) (MGI details for Pou1f1)

Pathways & Interactions
for POU1F1 gene

	Super-pathway	contained gene-specific pathways
1	Glucocorticoid receptor regulatory network	Glucocorticoid receptor regulatory network 1.00

1 BioSystems Pathway for POU1F1

Glucocorticoid receptor regulatory network

Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17):    About this table

Drugs & Compounds
for POU1F1 gene

Transcripts
for POU1F1 gene

Expression
for POU1F1 gene

POU1F1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAACTGAAA

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POU1F1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POU1F1
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POU1F1

Orthologs
for POU1F1 gene

Paralogs
for POU1F1 gene

Paralogs for POU1F1 gene

POU5F2²  POU6F2²  POU4F2²  POU2F3²  POU3F4²  POU3F1²  POU4F3²  POU3F3²  

POU3F2²  POU2F2²  POU5F1B²  POU2F1²  POU4F1²  POU5F1²  POU6F1²  

18/19 SIMAP similar genes for POU1F1 using alignment to 3 protein entries:     PIT1_HUMAN (see all proteins) (see all similar genes):

OCT6    POU6F1    POU5F1P4    POU3F1    POU3F4    POU4F1

OCT-2    POU3F3    POU5F1    POU2F3    POU2F1    POU2F2

POU5F1P1    POU3F2    POU5F1B    POU4F2    POU4F3    NKX2-5

POU1F1 for paralogs           About GeneDecksing

Genomic Variants
for POU1F1 gene

10/335 NCBI SNPs in POU1F1 are shown (see all 335)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs358936261,2	C,F,	non-pathogenic	87335780(-)	GAAACA/TCAGCA	3	T S	int1 mis1		6		MN CSA	410
rs1048937551,2	C	pathogenic	87322338(-)	AAAAAC/TGGGTG	4	R W	mis1		0	--	--	--	--
rs1048937621,2	C	pathogenic	87322434(-)	ATAAAC/TCTTCT	4	P S	mis1		0	--	--	--	--
rs1048937641,2	C	pathogenic	87322461(-)	CTCTGA/GAGAGA	4	K E	mis1		0	--	--	--	--
rs1048937661,2	C	pathogenic	87324501(-)	CTCAGC/GTTTAA	4	S R	mis1		0	--	--	--	--
rs1048937651,2	C	pathogenic	87324523(-)	CTGCCA/GATTTG	4	Q R	mis1		0	--	--	--	--
rs1048937541,2	C	pathogenic	87324524(-)	TCTGCC/TGATTT	4	R *	stg1		0	--	--	--	--
rs1048937631,2	C	pathogenic	87326657(-)	GAATTA/TAATTA	4	K *	stg1		0	--	--	--	--
rs1048937611,2	C	pathogenic	87326686(-)	AAAGTG/TTGCCA	4	C F	mis1		0	--	--	--	--
rs1823891861,2		--	87308297(+)	CCCTGA/GAGAGG	2	--	ds5001		0	--	--	--	--

HapMap Linkage Disequilibrium report for POU1F1 (87308554 - 87325737 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for POU1F1: --
Human Gene Mutation Database (HGMD): POU1F1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POU1F1

DNA2.0 Custom Variant and Variant Library Synthesis for POU1F1

Disorders / Diseases
for POU1F1 gene

20/41 diseases for POU1F1

10/29 Novoseek disease relationships for POU1F1 gene (see all 29)    About this table

Publications
for POU1F1 gene

PubMed articles for POU1F1 gene, integrated from 9 sources (see all 356) (see top 10): (articles sorted by number of sources associating them with POU1F1)

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1. Novel mutations within the POU1F1 gene associated with variable combined pituitary hormone deficiency. (PubMed id 15928241)^{1, 2, 4, 9} Turton J.P....Dattani M.T. (2005)
2. Cloning of the human cDNA for transcription factor Pit-1. (PubMed id 1956794)^{1, 2, 3} Lew A.M. and Elsholtz H.P. (1991)
3. Central hypothyroidism reveals compound heterozygous mutations in the Pit-1 gene. (PubMed id 9485179)^{1, 2, 9} Brown M.R.... Hurley D.L. (1998)
4. Mutations in the Pit-1 gene in children with combined pituitary hormone deficiency. (PubMed id 1472057)^{1, 2, 9} Ohta K.... Matsuda I. (1992)
5. Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study. (PubMed id 16214911)^{1, 4, 9} Canzian F....Kaaks R. (2005)
6. Combined pituitary hormone deficiency caused by compound heterozygosity for two novel mutations in the POU domain of the PIT1/POU1F1 gene. (PubMed id 11297581)^{1, 2, 9} Hendriks-Stegeman B.I.... Jansen M. (2001)
7. Pro239Ser: a novel recessive mutation of the Pit-1 gene in seven Middle Eastern children with growth hormone, prolactin, and thyrotropin deficiency. (PubMed id 9626142)^{1, 2, 9} Pernasetti F.M.... Martial J.A. (1998)
8. A new mutation of the gene encoding the transcription factor Pit-1 is responsible for combined pituitary hormone deficiency. (PubMed id 8768831)^{1, 2, 9} Pellegrini-Bouiller I.... Enjalbert A. (1996)
9. A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency. (PubMed id 1509262)^{1, 2, 9} Radovick S....Wondisford F.E. (1992)
10. Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia. (PubMed id 1509263)^{1, 2, 9} Pfaeffle R.W....Ingraham H.A. (1992)
11. A novel pituitary transcription factor is produced by alternative splicing of the human GHF-1/PIT-1 gene. (PubMed id 7721104)^{1, 2} Delhase M.... Castrillo J.-L. (1995)
12. Cloning of a human GHF-1/Pit-1 cDNA variant. (PubMed id 8346040)^{1, 2} Pernasetti F.M.... Martial J.A. (1993)
13. Characterization of the gene encoding human pituitary-specific transcription factor, Pit-1. (PubMed id 1487156)^{1, 2} Ohta K.... Matsuda I. (1992)
14. Nucleotide sequence of the complementary DNA for human Pit-1/GHF-1. (PubMed id 1370379)^{1, 2} Tatsumi K.I.... Miyai K. (1992)
15. Pit-1 is expressed in normal and tumorous human breast and regulates GH secretion and cell proliferation. (PubMed id 16061841)^{1, 9} Gil-Puig C....Perez-Fernandez R. (2005)
16. The role of CBP/p300 interactions and Pit-1 dimerization in the pathophysiological mechanism of combined pituitary hormone deficiency. (PubMed id 16263824)^{1, 9} Cohen R.N....Radovick S. (2006)
17. Expression of Pit-1 in nonsomatotrope cell lines indu ces human growth hormone locus control region histone modification and hGH-N tr anscription. (PubMed id 19427323)^{1, 9} Hogan K.A....Shewchuk B.M. (2009)
18. The Pit-1/Pou1f1 transcription factor regulates and c orrelates with prolactin expression in human breast cell lines and tumors. (PubMed id 19808898)^{1, 9} Ben-Batalla I....Perez-Fernandez R. (2010)
19. Expression of the synaptotagmin I gene is enhanced by binding of the pituitary-specific transcription factor, POU1F1. (PubMed id 19608642)^{1, 9} Howard P.W....Maurer R.A. (2009)
20. The vitamin D receptor represses transcription of the pituitary transcription factor Pit-1 gene without involvement of the retinoid X receptor. (PubMed id 16322098)^{1, 9} Seoane S. and Perez-Fernandez R. (2006)
21. Involvement of the pituitary-specific transcription factor pit-1 in somatolactotrope cell growth and death: an approach using dominant-negative pit-1 mutants. (PubMed id 16901973)^{1, 9} Pellegrini I....Franc J.L. (2006)
22. The R271W mutant form of Pit-1 does not act as a dominant inhibitor of Pit-1 action to activate the promoters of GH and prolactin genes. (PubMed id 12773133)^{1, 9} Kishimoto M....Chihara K. (2003)
23. Novel function of the transactivation domain of a pituitary-specific transcription factor, Pit-1. (PubMed id 12200420)^{1, 9} Kishimoto M....Chihara K. (2002)
24. Expression of pit-1 messenger ribonucleic acid and protein in the human placenta. (PubMed id 7608249)^{1, 9} Bamberger A.M....Asa S.L. (1995)
25. Cellular expression levels of the vitamin D receptor are critical to its transcriptional regulation by the pituitary transcription factor Pit-1. (PubMed id 17456792)^{1, 9} Seoane S....Perez-Fernandez R. (2007)
26. Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus. (PubMed id 16030140)^{1, 9} Voss T.C....Day R.N. (2005)
27. A 'hot spot' in the Pit-1 gene responsible for combined pituitary hormone deficiency: clinical and molecular correlates. (PubMed id 7852536)^{2, 9} Cohen L.E.... Radovick S. (1995)
28. Identification and analysis of prophet of Pit-1-binding sites in human Pit-1 gene. (PubMed id 18653712)^{1, 9} Ikeshita N....Okimura Y. (2008)
29. MED220/thyroid receptor-associated protein 220 functions as a transcriptional coactivator with Pit-1 and GATA-2 on the thyrotropin-beta promoter in thyrotropes. (PubMed id 16396960)^{1, 9} Gordon D.F....Ridgway E.C. (2006)
30. Expression of Pit-1 and growth hormone-releasing hormone receptor mRNA in human pituitary adenomas: difference among functioning, silent, and other nonfunctioning adenomas. (PubMed id 12165656)^{1, 9} Kobayashi I....Kameya T. (2002)
31. Pit-1 gene expression in the human pituitary and pituitary adenomas. (PubMed id 8027225)^{1, 9} Pellegrini I.... Jaquet P. (1994)
32. The transcription factor Pit-1/GHF-1 is expressed in hemopoietic and lymphoid tissues. (PubMed id 8458380)^{1, 9} Delhase M....Hooghe R.J. (1993)
33. Positive association between POU1F1 and mental retardation in young females in the Chinese Han population. (PubMed id 16505001)^{1, 9} Sun Y....He L. (2006)
34. A novel nonsense mutation in the Pit-1 gene: evidence for a gene dosage effect. (PubMed id 12629113)^{1, 9} Hashimoto Y....Cohen L.E. (2003)
35. Clinical characteristics and molecular analysis of PIT1, PROP1,LHX3, and HESX1 in combined pituitary hormone deficiency patients with abnormal pituitary MR imaging. (PubMed id 14646405)^{1, 9} Kim S.S....Yoo H.W. (2003)
36. Combined pituitary hormone deficiency due to the F135C human Pit-1 (pituitary-specific factor 1) gene mutation: functional and structural correlates. (PubMed id 11222742)^{1, 9} Vallette-Kasic S....Brue T. (2001)
37. The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities. (PubMed id 9685346)^{1, 9} Amendt B.A....Russo A.F. (1998)
38. The glucocorticoid receptor inhibits the human prolactin gene expression by interference with Pit-1 activity. (PubMed id 9426156)^{1, 9} Nalda A.M....Muller M. (1997)
39. Pituitary dwarfism in the R271W Pit-1 gene mutation. (PubMed id 9392392)^{1, 9} Aarskog D....Myking O.L. (1997)
40. Monoallelic expression of normal mRNA in the PIT1 mutation heterozygotes with normal phenotype and biallelic expression in the abnormal phenotype. (PubMed id 7833912)^{1, 9} Okamoto N....Tatsumi K. (1994)
41. Functional relationship between LHX4 and POU1F1 in light of the LHX4 mutation identified in patients with pituitary defects. (PubMed id 15998782)^{1, 9} Machinis K. and Amselem S. (2005)
42. Activin inhibits pituitary prolactin expression and cell growth through Smads, Pit-1 and menin. (PubMed id 15031321)^{1, 9} Lacerte A....Lebrun J.J. (2004)
43. Cellular determination in the anterior pituitary gland: PIT-1 and PROP-1 mutations as causes of human combined pituitary hormone deficiency. (PubMed id 12717343)^{1, 9} Rodriguez R. and Andersen B. (2003)
44. A novel mutation in PIT-1: phenotypic variability in familial combined pituitary hormone deficiencies. (PubMed id 11924936)^{1, 9} Gat-Yablonski G....Phillip M. (2002)
45. Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors. (PubMed id 11891224)^{1, 9} Gonzalez M.M. and Carlberg C. (2002)
46. Structural characterization of the PIT-1/ETS-1 interaction: PIT-1 phosphorylation regulates PIT-1/ETS-1 binding. (PubMed id 12242337)^{1, 9} Augustijn K.D....van der Vliet P.C. (2002)
47. Transcription factors regulating pituitary development. (PubMed id 10549299)^{1, 9} Parks J.S. and Brown M.R. (1999)
48. Signal-specific co-activator domain requirements for Pit-1 activation. (PubMed id 9751061)^{1, 9} Xu L....Rosenfeld M.G. (1998)
49. Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression. (PubMed id 9032233)^{1, 9} Bradford A.P....Gutierrez-Hartmann A. (1997)
50. A novel E250X mutation of the PIT1 gene in a patient with combined pituitary hormone deficiency. (PubMed id 7670563)^{1, 9} Irie Y....Amino N. (1995)
51. W194XProp1 and S156insTProp1, both of which have inta ct DNA-binding domain, show a different DNA-binding activity to the Prop1-bindi ng element in human Pit-1 gene. (PubMed id 20381582)^{1, 9} Shibahara H....Okimura Y. (2010)
52. A novel germline mutation, IVS4+1G>A, of the POU1F1 gene underlying combined pituitary hormone deficiency. (PubMed id 18059085)^{1, 9} Snabboon T....Shotelersuk V. (2008)
53. Pituitary transcription factors: from congenital deficiencies to gene therapy. (PubMed id 16879162)^{1, 9} Quentien M.H....Enjalbert A. (2006)
54. Identification and functional analysis of the novel S179R POU1F1 mutation associated with combined pituitary hormone deficiency. (PubMed id 16968807)^{2, 9} Miyata I....Brue T. (2006)
55. Induction of GH, PRL, and TSH beta mRNA by transfection of Pit-1 in a human pituitary adenoma-derived cell line. (PubMed id 16133148)^{1, 9} Miyai S....Osamura R.Y. (2005)
56. New N-terminal located mutation (Q4ter) within the POU1F1-gene (PIT-1) causes recessive combined pituitary hormone deficiency and variable phenotype. (PubMed id 12932747)^{1, 9} Salemi S....Mullis P.E. (2003)
57. Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter. (PubMed id 12223489)^{1, 9} Quentien M.H....Pellegrini I. (2002)
58. A new C-terminal located mutation (V272ter) in the PIT-1 gene manifesting with severe congenital hypothyroidism. Possible functionality of the PIT-1 C-terminus. (PubMed id 11847467)^{1, 9} Blankenstein O....Heimann G. (2001)
59. Description of a Brazilian patient bearing the R271W Pit-1 gene mutation. (PubMed id 9588494)^{1, 9} Rodrigues Martineli A.M....Graf H. (1998)
60. P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development. (PubMed id 8755540)^{1, 9} Szeto D.P....Rosenfeld M.G. (1996)
61. The prenatal role of thyroid hormone evidenced by fetomaternal Pit-1 deficiency. (PubMed id 7593413)^{1, 9} de Zegher F....Martial J.A. (1995)
62. Cretinism with combined hormone deficiency caused by a mutation in the PIT1 gene. (PubMed id 1302000)^{1, 9} Tatsumi K....Kohno H. (1992)
63. PIT1 upregulation by HMGA proteins has a role in pitui tary tumorigenesis. (PubMed id 22199144)¹ Palmieri D....Fedele M. (2012)
64. POU1F1-mediated activation of hGH-N by deoxyribonuclea se I hypersensitive site II of the human growth hormone locus control region. (PubMed id 22094313)¹ Hunsaker T.L....Shewchuk B.M. (2012)
65. Identification of a novel mutation in the exon 2 splic e donor site of the POU1F1/PIT-1 gene in Japanese identical twins with mild comb ined pituitary hormone deficiency. (PubMed id 21722153)¹ Inoue H....Fujieda K. (2012)
66. Research resource: A genome-wide study identifies pote ntial new target genes for POU1F1. (PubMed id 22638072)¹ Herman J.P....Franc J.L. (2012)
67. A novel POU1F1 mutation (p.Thr168IlefsX7) associated with an early and severe form of combined pituitary hormone deficiency: functio nal analysis and follow-up from infancy to adulthood. (PubMed id 21521297)¹ Tenenbaum-Rakover Y....Amselem S. (2011)
68. CEBPD suppresses prolactin expression and prolactinoma cell proliferation. (PubMed id 21980073)¹ Tong Y....Melmed S. (2011)
69. Pit-1 mutation and lipoedema in a family. (PubMed id 19609847)¹ Bano G....Nussey S. (2010)
70. Appearance of the pituitary factor Pit-1 increases ch romatin remodeling at hypersensitive site III in the human GH locus. (PubMed id 20395397)¹ Yang X....Cattini P.A. (2010)
71. CTNNB1 gene mutations, pituitary transcription factor s, and MicroRNA expression involvement in the pathogenesis of adamantinomatous craniopharyngiomas. (PubMed id 21761366)¹ Campanini M.L....de Castro M. (2010)
72. Mutation and gene copy number analyses of six pituita ry transcription factor genes in 71 patients with combined pituitary hormone de ficiency: identification of a single patient with LHX4 deletion. (PubMed id 20534763)¹ Dateki S....Ogata T. (2010)
73. A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin g ene promoter. (PubMed id 19887646)¹ Jean A....Duval D.L. (2010)
74. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)¹ Liu C.Y....Christiani D.C. (2010)
75. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)¹ He C....Hunter D.J. (2010)
76. Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolis m and breast cancer risk in the NCI breast and prostate cancer cohort consortiu m. (PubMed id 20634197)¹ Canzian F....Feigelson H.S. (2010)
77. Deregulation of the Pit-1 transcription factor in hum an breast cancer cells promotes tumor growth and metastasis. (PubMed id 21060149)¹ Ben-Batalla I....Perez-Fernandez R. (2010)
78. Eighteen insulin-like growth factor pathway genes, ci rculating levels of IGF-I and its binding protein, and risk of prostate and bre ast cancer. (PubMed id 20810604)¹ Gu F....Kraft P. (2010)
79. The 26-amino acid beta-motif of the Pit-1beta transcr iption factor is a dominant and independent repressor domain. (PubMed id 19556346)¹ Jonsen M.D....Gutierrez-Hartmann A. (2009)
80. The CPPDD-associated ANKH M48T mutation interrupts th e interaction of ANKH with the sodium/phosphate cotransporter PiT-1. (PubMed id 19369455)¹ Wang J....Tsui F.W. (2009)
81. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)¹ Yerges L.M....Zmuda J.M. (2009)
82. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
83. Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. (PubMed id 18514160)¹ Arnaud-Lopez L....Naitza S. (2008)
84. Sodium-dependent phosphate cotransporters and vascular calcification. (PubMed id 17565274)¹ Li X. and Giachelli C.M. (2007)
85. Differential utilization of transcription activation subdomains by distinct coactivators regulates Pit-1 basal and Ras responsiveness. (PubMed id 17021049)¹ Duval D.L....Gutierrez-Hartmann A. (2007)
86. Activin inhibits the human Pit-1 gene promoter through the p38 kinase pathway in a Smad-independent manner. (PubMed id 16740974)¹ de Guise C....Lebrun J.J. (2006)
87. Regulation of the human growth hormone gene family: possible role for Pit-1 in early stages of pituitary-specific expression and repression. (PubMed id 17047377)¹ Cattini P.A....Detillieux K.A. (2006)
88. Borjeson-Forssman-Lehmann syndrome: a novel pituitary phenotype due to mutation in a novel gene. (PubMed id 14714741)¹ Dattani M.T. (2003)
89. Dominant negative dimerization of a mutant homeodomain protein in Axenfeld-Rieger syndrome. (PubMed id 12612071)¹ Saadi I....Russo A.F. (2003)
90. Specification of unique Pit-1 activity in the hGH locus control region. (PubMed id 12189206)¹ Shewchuk B.M....Cooke N.E. (2002)
91. Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. (PubMed id 10367888)¹ Dasen J.S....Rosenfeld M.G. (1999)
92. Structure and regulation of the human growth hormone-releasing hormone receptor gene. (PubMed id 9482665)¹ Petersenn S....Schulte H.M. (1998)
93. Nuclear factor 1 regulates the distal silencer of the human PIT1/GHF1 gene. (PubMed id 9639565)¹ Rajas F....Hooghe-Peters E.L. (1998)
94. The c-Jun delta-domain inhibits neuroendocrine promoter activity in a DNA sequence- and pituitary-specific manner. (PubMed id 8663380)¹ Farrow K.N....Gutierrez-Hartmann A. (1996)
95. Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression. (PubMed id 8370519)¹ Lipkin S.M....Rosenfeld M.G. (1993)
96. Expression of a large family of POU-domain regulatory genes in mammalian brain development. (PubMed id 2739723)¹ He X....Rosenfeld M.G. (1989)
97. The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein. (PubMed id 2902927)¹ Bodner M....Karin M. (1988)
98. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. (PubMed id 3215510)¹ Herr W....Ruvkun G. (1988)
99. Cloning of the full length pig PIT1 (POU1F1) CDNA and a novel alternative PIT1 transcript, and functional studies of their encoded proteins. (PubMed id 11370678)⁹ Yu T.P....Tuggle C.K. (2001)
100. Pit-1 gene expression in human pituitary adenomas. (PubMed id 9167960)⁹ Pellegrini-Bouiller I....Jaquet P. (1997)
101. The ontogeny of pit-1 expression in the human fetal pituitary gland. (PubMed id 8739890)⁹ Puy L.A. and Asa S.L. (1996)
102. [Homeoproteins and pituitary adenoma] (PubMed id 9207961)⁹ Barlier A....Enjalbert A. (1997)
103. Thyroid hormone receptor beta2 promoter activity in pituitary cells is regulated by Pit-1. (PubMed id 8798664)⁹ Wood W.M....Ridgway E.C. (1996)
104. Pit-1 gene expression in human pituitary adenomas using the reverse transcription polymerase chain reaction method. (PubMed id 8949563)⁹ Yamada S....Usui M. (1996)
105. Constitutively active G(S) alpha-subunits stimulate Pit-1 promoter activity via a protein kinase A-mediated pathway acting through deoxyribonucleic acid binding sites both for Pit-1 and for adenosine 3',5'-monophosphate response element-binding protein. (PubMed id 8625901)⁹ Gaiddon C....Bancroft C. (1996)
106. In situ hybridization analysis of Pit-1 mRNA and hormonal production in human pituitary adenomas. (PubMed id 8834538)⁹ Sanno N....Osamura R.Y. (1996)
107. Imaging the localized protein interactions between Pit-1 and the CCAAT/enhancer binding protein alpha in the living pituitary cell nucleus. (PubMed id 12554785)⁹ Day R.N....Schaufele F. (2003)
108. Correlation of Pit-1 gene expression and Pit-1 content with proliferation and differentiation in human myeloid leukemic cells. (PubMed id 9828108)⁹ Costoya J.A....Devesa J. (1998)
109. Cell type-specific expression of the pituitary transcription activator pit-1 in the human pituitary and pituitary adenomas. (PubMed id 8077321)⁹ Asa S.L....Elsholtz H.P. (1993)
110. Inactivating Pit-1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response. (PubMed id 15211565)⁹ Sharp Z.D....Mancini M.A. (2004)
111. The tissue-specific transcription factor Pit-1/GHF-1 binds to the c-fos serum response element and activates c-fos transcription. (PubMed id 10319324)⁹ Gaiddon C....Loeffler J.P. (1999)
112. Control of growth hormone synthesis. (PubMed id 8625613)⁹ Tuggle C.K. and Trenkle A. (1996)
113. Role of Pit-1 in the gene expression of growth hormone, prolactin, and thyrotropin. (PubMed id 8879985)⁹ Cohen L.E....Radovick S. (1996)
114. Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain. (PubMed id 7649480)⁹ Holloway J.M....Rosenfeld M.G. (1995)
115. The combination of Pit-1 and Pit-1T have a synergistic stimulatory effect on the thyrotropin beta-subunit promoter but not the growth hormone or prolactin promoters. (PubMed id 7877626)⁹ Haugen B.R....Ridgway E.C. (1994)
116. Synergistic activation of the rat growth hormone promoter by Pit-1 and the thyroid hormone receptor. (PubMed id 1584227)⁹ Schaufele F....Baxter J.D. (1992)
117. Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. (PubMed id 2379827)⁹ Simmons D.M....Swanson L.W. (1990)
118. Extrapituitary TSH in early chick embryos: Pit-1 dependence? (PubMed id 11931353)⁹ Murphy A.E. and Harvey S. (2002)
119. The molecular basis of hypopituitarism. (PubMed id 9554467)⁹ Radovick S....Wondisford F.E. (1998)
120. Expression of Pit-1 and estrogen receptor messenger RNA in prolactin-producing pituitary adenomas. (PubMed id 8733768)⁹ Sanno N....Osamura R.Y. (1996)
121. Pituitary-type transcription of the human prolactin gene in the absence of Pit-1. (PubMed id 7476971)⁹ Gellersen B....DiMattia G.E. (1995)
122. Pituitary specific transcription factor messenger ribonucleic expression in adenomatous and nontumorous human pituitary tissues. (PubMed id 8246449)⁹ Lloyd R.V....Kovacs K. (1993)
123. Hormonal regulation of the thyrotropin beta-subunit gene by phosphorylation of the pituitary-specific transcription factor Pit-1. (PubMed id 1321428)⁹ Steinfelder H.J....Wondisford F.E. (1992)
124. Functions of PIT1 in GATA2-dependent transactivation of the thyrotropin beta promoter. (PubMed id 19103719)⁹ Kashiwabara Y....Nakamura H. (2009)
125. Local expression of a POU family transcription factor, Pit-1, in the rat placenta. (PubMed id 8735586)⁹ Lee B.J....Choi W.S. (1996)
126. A dopamine-responsive domain in the N-terminal sequence of Pit-1. Transcriptional inhibition in endocrine cell types. (PubMed id 7706253)⁹ Lew A.M. and Elsholtz H.P. (1995)
127. Differential splicing of the GHF1 primary transcript gives rise to two functionally distinct homeodomain proteins. (PubMed id 1600947)⁹ Theill L.E....Karin M. (1992)
128. Involvement of mPOU (Brn-5), a class VI POU protein, in the gene expression of Pit-1 as well as PRL. (PubMed id 17933456)⁹ Toda K....Okimura Y. (2008)
129. Basic science and clinical research advances in the pituitary transcription factors: Pit-1 and Prop-1. (PubMed id 18594277)⁹ Kerr J....Ridgway E.C. (2008)
130. Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSH beta gene. (PubMed id 12385825)⁹ Gordon D.F....Ridgway E.C. (2002)
131. Rarity of PIT1 involvement in children from Russia with combined pituitary hormone deficiency. (PubMed id 9632165)⁹ Fofanova O.V....Yamashita S. (1998)
132. Expression of Pit-1 mRNA and activin/inhibin subunits in clinically nonfunctioning pituitary adenomas. In situ hybridization and immunohistochemical analysis. (PubMed id 9691207)⁹ Sanno N....Osamura R.Y. (1998)
133. Pit-1/growth hormone factor 1 splice variant expression in the rhesus monkey pituitary gland and the rhesus and human placenta. (PubMed id 9062486)⁹ Schanke J.T....Golos T.G. (1997)
134. Activin increases phosphorylation and decreases stability of the transcription factor Pit-1 in MtTW15 somatotrope cells. (PubMed id 7499395)⁹ Gaddy-Kurten D. and Vale W.W. (1995)
135. Thyrotropin releasing hormone stimulates transient phosphorylation of the tissue-specific transcription factor, Pit-1. (PubMed id 7961816)⁹ Howard P.W. and Maurer R.A. (1994)
136. Pit-1 messenger ribonucleic acid is differentially expressed in human pituitary adenomas. (PubMed id 8077322)⁹ Friend K.E....Shupnik M.A. (1993)
137. PROP1, HESX1, POU1F1, LHX3 and LHX4 mutation and dele tion screening and GH1 P89L and IVS3+1/+2 mutation screening in a Dutch nationw ide cohort of patients with combined pituitary hormone deficiency. (PubMed id 20389107)⁹ de Graaff L.C....Hokken-Koelega A.C. (2010)
138. OTX2 mutation in a patient with anophthalmia, short stature, and partial growth hormone deficiency: functional studies using the IRBP, HESX1, and POU1F1 promoters. (PubMed id 18628516)⁹ Dateki S....Ogata T. (2008)
139. A single base difference between Pit-1 binding sites at the hGH promoter and locus control region specifies distinct Pit-1 conformations and functions. (PubMed id 16914737)⁹ Shewchuk B.M....Cooke N.E. (2006)
140. Repression of the prolactin promoter: a functional consequence of the heterodimerization between Pit-1 and Pit-1 beta. (PubMed id 16216912)⁹ Sporici R.A....Diamond S.E. (2005)
141. The pituitary-specific transcription factor, Pit-1, can direct changes in the chromatin structure of the prolactin promoter. (PubMed id 15375187)⁹ Kievit P. and Maurer R.A. (2005)
142. Immunolocalization of Pit-1 in gonadotroph nuclei is indicative of the transdifferentiation of gonadotroph to lactotroph cells in prolactinomas induced by estrogen. (PubMed id 15221415)⁹ Mukdsi J.H....Torres A.I. (2004)
143. Combined pituitary hormone deficiency in Australian children: clinical and genetic correlates. (PubMed id 12780757)⁹ McLennan K....Choong C. (2003)
144. A PIT-1 homeodomain mutant blocks the intranuclear recruitment of the CCAAT/enhancer binding protein alpha required for prolactin gene transcription. (PubMed id 12554749)⁹ Enwright J.F....Day R.N. (2003)
145. Expression of GATA-2 in human pituitary adenomas. (PubMed id 11796836)⁹ Umeoka K....Teramoto A. (2002)
146. Combined pituitary hormone deficiency: role of Pit-1 and Prop-1. (PubMed id 10626543)⁹ Pfaffle R.W....Kentrup H. (1999)
147. Defective retinoic acid regulation of the Pit-1 gene enhancer: a novel mechanism of combined pituitary hormone deficiency. (PubMed id 10077004)⁹ Cohen L.E....Radovick S. (1999)
148. A Pit-1 phosphorylation mutant can mediate both basal and induced prolactin and growth hormone promoter activity. (PubMed id 7877625)⁹ Fischberg D.J....Bancroft C. (1994)
149. Expression of Pit-1 and related proteins in diverse human pituitary adenomas. (PubMed id 8148036)⁹ Hoggard N....Davis J.R. (1993)
150. Mediation by calcium of thyrotropin--releasing hormone action on the prolactin promoter via transcription factor pit-1. (PubMed id 1775132)⁹ Yan G.Z. and Bancroft C. (1991)
151. Vitamin D, Pit-1, GH, and PRL: possible roles in breast cancer development. (PubMed id 18220741)⁹ Perez-Fernandez R....Macia M. (2007)
152. Dynamic interactions between Pit-1 and C/EBPalpha in the pituitary cell nucleus. (PubMed id 16908544)⁹ Demarco I.A....Day R.N. (2006)
153. Cloning of a protein binding to the most proximal Pit-1 binding element of prolactin gene from human pituitary cDNA library. (PubMed id 12972181)⁹ Fumoto M....Chihara K. (2003)
154. Parathyroid hormone regulation of bone sialoprotein (BSP) gene transcription is mediated through a pituitary-specific transcription factor-1 (Pit-1) motif in the rat BSP gene promoter. (PubMed id 10980416)⁹ Ogata Y....Sodek J. (2000)
155. PIT1 abnormality. (PubMed id 10549301)⁹ Tatsumi K. and Amino N. (1999)
156. Pit-1 gene expression in human lactotroph and somatotroph pituitary adenomas is correlated to D2 receptor gene expression. (PubMed id 8784102)⁹ Pellegrini-Bouiller I....Enjalbert A. (1996)
157. Expression of human Pit-1 product in the human pituitary and pituitary adenomas. Immunohistochemical studies using an antibody against synthetic human Pit-1 product. (PubMed id 8554449)⁹ Sanno N....Osamura R.Y. (1996)
158. M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding. (PubMed id 8524234)⁹ Caelles C....Karin M. (1995)
159. Clinical and immunohistochemical studies on TSH-secreting pituitary adenoma: its multihormonality and expression of Pit-1. (PubMed id 7892156)⁹ Sanno N....Osamura R.Y. (1994)
160. Pituitary-specific transcription factor (Pit-1) binding site in the human renin gene 5'-flanking DNA stimulates promoter activity in placental cell primary cultures and pituitary lactosomatotropic cell lines. (PubMed id 7923608)⁹ Sun J....Catanzaro D.F. (1994)
161. Immunohistochemical expression of PIT-1 protein in pituitary glands of human GRF transgenic mice: its relationship with hormonal expressions. (PubMed id 7951487)⁹ Osamura R.Y....Rosenfeld M.G. (1993)
162. Pit-1 and pituitary function. (PubMed id 7920987)⁹ PfAoffle R.W....Heimann G. (1993)
163. Functional isoforms of Pit-1 generated by alternative messenger RNA splicing. (PubMed id 1569967)⁹ Konzak K.E. and Moore D.D. (1992)
164. Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements. (PubMed id 1652153)⁹ Kapiloff M.S....Rosenfeld M.G. (1991)
165. The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. (PubMed id 2350782)⁹ Ingraham H.A....Rosenfeld M.G. (1990)
166. Heterozygous orthodenticle homeobox 2 mutations are a ssociated with variable pituitary phenotype. (PubMed id 19965921)⁹ Dateki S....Ogata T. (2010)
167. Molecular analysis of PROP1, PIT1, HESX1, LHX3, and LHX4 shows high frequency of PROP1 mutations in patients with familial forms of combined pituitary hormone deficiency. (PubMed id 18157385)⁹ Vieira T.C....Abucham J. (2007)
168. Clinical characteristics, etiologies and pathophysiology of patients with severe short stature with severe GH deficiency: questionnaire study on the data registered with the foundation for growth science, Japan. (PubMed id 16618986)⁹ Hanew K....Fujita K. (2006)
169. Ovis aries POU1F1 gene: cloning, characterization and polymorphism analysis. (PubMed id 16636924)⁹ Bastos E....Renaville R. (2006)
170. Three novel mutations in POU1F1 in Israeli patients with combined pituitary hormone deficiency. (PubMed id 15844473)⁹ Gat-Yablonski G....Phillip M. (2005)
171. Magnetic resonance imaging of the hypothalamus-pituitary unit in childrensuspected of hypopituitarism: who, how and when toinvestigate. (PubMed id 15279086)⁹ Maghnie M....Genovese E. (2004)
172. Effect of GHRH and GHRP-2 treatment in vitro on GH secretion and levels of GH, pituitary transcription factor-1, GHRH-receptor, GH-secretagogue-receptor and somatostatin receptor mRNAs in ovine pituitary cells. (PubMed id 14763922)⁹ Yan M....Chen C. (2004)
173. The de novo Q167K mutation in the POU1F1 gene leads to combined pituitary hormone deficiency in an Italian patient. (PubMed id 12904605)⁹ Malvagia S....Zammarchi E. (2003)
174. Exogenous expression of Pit-1 in AtT-20 corticotropic cells induces endogenous growth hormone gene transcription. (PubMed id 11874696)⁹ Kurotani R....Osamura R.Y. (2002)
175. Pituitary magnetic resonance imaging and function in patients with growth hormone deficiency with and without mutations in GHRH-R, GH-1, or PROP-1 genes. (PubMed id 12414875)⁹ Osorio M.G....Arnhold I.J. (2002)
176. Impact of gsp oncogene on the expression of genes coding for Gsalpha, Pit-1, Gi2alpha, and somatostatin receptor 2 in human somatotroph adenomas: involvement in octreotide sensitivity. (PubMed id 10443675)⁹ Barlier A....Enjalbert A. (1999)
177. Pit-1 positive alpha-subunit positive nonfunctioning human pituitary adenomas: a dedifferentiated GH cell lineage? (PubMed id 11081207)⁹ Osamura R.Y....Teramoto A. (1999)
178. Regulation of estrogen receptor activation of the prolactin enhancer/promoter by antagonistic activation function-2-interacting proteins. (PubMed id 10379892)⁹ Schaufele F. (1999)
179. Prop-1 gene expression in human pituitary tumors. (PubMed id 10404841)⁹ Nakamura S....Yamashita S. (1999)
180. Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation. (PubMed id 10585453)⁹ Shewchuk B.M....Liebhaber S.A. (1999)
181. Subnuclear partitioning and functional regulation of the Pit-1 transcription factor. (PubMed id 10022514)⁹ Mancini M.G....Mancini M.A. (1999)
182. Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1). (PubMed id 10406465)⁹ Castillo A.I....Aranda A. (1999)
183. Transcription factor AP1 is involved in basal and okadaic acid-stimulated activity of the human PRL promoter. (PubMed id 9717847)⁹ Caccavelli L....Muller M. (1998)
184. [The pituitary specific transcription factor Pit-1/GHF-1 and PIT1 abnormality] (PubMed id 9256012)⁹ Tatsumi K. and Amino N. (1997)
185. A case of pituitary somatotroph adenoma with concomitant secretion of growth hormone, prolactin, and adrenocorticotropic hormone--an adenoma derived from primordial stem cell, studied by immunohistochemistry, in situ hybridization, and cell culture. (PubMed id 8890999)⁹ Matsuno A....Kirino T. (1996)
186. Transcriptional induction of the human renin gene by cyclic AMP requires cyclic AMP response element-binding protein (CREB) and a factor binding a pituitary-specific trans-acting factor (Pit-1) motif. (PubMed id 8645191)⁹ Germain S....Pinet F. (1996)
187. Screening for PIT1 abnormality by PCR direct sequencing method. (PubMed id 7580269)⁹ Irie Y....Amino N. (1995)
188. Renin gene promoter activity in GC cells is regulated by cAMP and thyroid hormone through Pit-1-dependent mechanisms. (PubMed id 7961740)⁹ Gilbert M.T....Catanzaro D.F. (1994)
189. Genetics of growth hormone gene expression. (PubMed id 8300051)⁹ Parks J.S....Brown M.R. (1993)
190. Inhibitory control of prolactin and Pit-1 gene promoters by dopamine. Dual signaling pathways required for D2 receptor-regulated expression of the prolactin gene. (PubMed id 1835974)⁹ Elsholtz H.P....Sundmark V.C. (1991)
191. Pituitary adenomas that show a faint GH-immunoreactiv ity but lack fibrous body: Pit-1 adenoma with endocrinologically low activity. (PubMed id 20111911)⁹ Yoneda A....Kudo E. (2010)
192. PROP1 coexists with SOX2 and induces PIT1-commitment cells. (PubMed id 19442651)⁹ Yoshida S....Kato Y. (2009)
193. Hypopituitarism oddities: congenital causes. (PubMed id 18174732)⁹ Kelberman D. and Dattani M.T. (2007)
194. Associations of DNA polymorphisms in growth hormone and its transcriptional regulators with growth and carcass traits in two populations of Brangus bulls. (PubMed id 17469072)⁹ Thomas M.G....Silver G.A. (2007)
195. Genetic screening of combined pituitary hormone deficiency: experience in 195 patients. (PubMed id 16735499)⁹ Reynaud R....Barlier A. (2006)
196. The mimecan gene expressed in human pituitary and regulated by pituitary transcription factor-1 as a marker for diagnosing pituitary tumors. (PubMed id 16189248)⁹ Hu S.M....Song H.D. (2005)
197. Auxological and endocrine phenotype in a population-based cohort of patients with PROP1 gene defects. (PubMed id 16131601)⁹ Lebl J....Blum W.F. (2005)
198. Chromosomal translocation t(10;11)(q26;q13) in a woman with combined pituitary hormone deficiency. (PubMed id 15192287)⁹ Laml T....Hengstschlager M. (2004)
199. Isolated growth hormone deficiency and the GH-1 gene: update 2002. (PubMed id 12435888)⁹ Binder G. (2002)
200. Pit-1/GHF-1 and GH expression in the MCF-7 human breast adenocarcinoma cell line. (PubMed id 11927395)⁹ Gil-Puig C....PAcrez-FernA!ndez R. (2002)
201. Identification of a dominant negative homeodomain mutation in Rieger syndrome. (PubMed id 11301317)⁹ Saadi I....Russo A.F. (2001)
202. Transcriptional regulation of pituitary synthesis and secretion of growth hormone in growing wethers and the influence of zeranol on these mechanisms. (PubMed id 10793270)⁹ Thomas M.G....Keisler D.H. (2000)
203. Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo. (PubMed id 11036930)⁹ Rosenfeld M.G....Treier M. (2000)
204. Pituitary and extrapituitary growth hormone: Pit-1 dependence? (PubMed id 11149379)⁹ Harvey S....Hull K.L. (2000)
205. Transcriptional properties of Ptx1 and Ptx2 isoforms. (PubMed id 10859489)⁹ Tremblay J.J....Drouin J. (2000)
206. CREB-independent regulation by CBP is a novel mechanism of human growth hormone gene expression. (PubMed id 10525051)⁹ Cohen L.E....Radovick S. (1999)
207. Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity. (PubMed id 10194769)⁹ Fliss M.S....Bancroft C. (1999)
208. Characterization of Prophet of Pit-1 gene expression in normal pituitary and pituitary adenomas in humans. (PubMed id 10199788)⁹ Nakamura Y....Nakao K. (1999)
209. The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3. (PubMed id 9514159)⁹ Tremblay J.J....Drouin J. (1998)
210. Expression of an orphan nuclear receptor DAX-1 in human pituitary adenomas. (PubMed id 9666878)⁹ Ikuyama S....Nawata H. (1998)
211. Genetic basis of congenital hypothyroidism: abnormalities in the TSHbeta gene, the PIT1 gene, and the NIS gene. (PubMed id 9806481)⁹ Tatsumi K....Amino N. (1998)
212. Severe congenital hypopituitarism with low prolactin levels and age-dependent anterior pituitary hypoplasia: a clue to a PIT-1 mutation. (PubMed id 9627600)⁹ Ward L....Van Vliet G. (1998)
213. Activation of the prolactin gene by peroxisome proliferator-activated receptor-alpha appears to be DNA binding-independent. (PubMed id 9756906)⁹ Tolon R.M....Aranda A. (1998)
214. POU domain factors in neural development. (PubMed id 10026784)⁹ Schonemann M.D....Rosenfeld M.G. (1998)
215. Expression and alternative splicing of Pit-1 messenger ribonucleic acid in pituitary adenomas. (PubMed id 8869065)⁹ Hamada K....Ushio Y. (1996)
216. A 33 kDa Pit-1-like protein binds to the distal region of the human thyrotrophin alpha-subunit gene. (PubMed id 7669223)⁹ Kim D.S....Park S.D. (1995)
217. Thyrotropin-producing pituitary adenoma discovered as a pituitary incidentaloma. (PubMed id 8774963)⁹ Yamakita N....Miura K. (1995)
218. Expression of activin/inhibin subunit messenger ribonucleic acids by gonadotroph adenomas. (PubMed id 7962335)⁹ Haddad G....Snyder P.J. (1994)
219. Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma. (PubMed id 8015553)⁹ Gellersen B.... DiMattia G.E. (1994)
220. Differential binding of rat pituitary-specific nuclear factors to the 5'-flanking region of pituitary and placental members of the human growth hormone gene family. (PubMed id 1922020)⁹ Nickel B.E....Cattini P.A. (1991)
221. Transcriptional induction of the human prolactin gene by cAMP requires two cis-acting elements and at least the pituitary-specific factor Pit-1. (PubMed id 1655738)⁹ Peers B....Martial J.A. (1991)
222. Corepressors TLE1 and TLE3 interact with HESX1 and PR OP1. (PubMed id 20181723)⁹ Carvalho L.R....Camper S.A. (2010)
223. A novel loss-of-function mutation in OTX2 in a patien t with anophthalmia and isolated growth hormone deficiency. (PubMed id 20396904)⁹ Ashkenazi-Hoffnung L....Gat-Yablonski G. (2010)
224. Growth hormone deficiency (GHD) and small for gestati onal age (SGA): genetic alterations. (PubMed id 20087248)⁹ Jancevska A....Pop-Jordanova N. (2009)
225. Genetics, gene expression and bioinformatics of the pituitary gland. (PubMed id 19407506)⁹ Davis S.W....Camper S.A. (2009)
226. OTX2 loss of function mutation causes anophthalmia and combined pituitary hormone deficiency with a small anterior and ectopic posterior pituitary. (PubMed id 18854396)⁹ Tajima T....Fujieda K. (2009)
227. A novel recessive splicing mutation in the POU1F1 gen e causing combined pituitary hormone deficiency. (PubMed id 19498317)⁹ Carlomagno Y....Giordano M. (2009)
228. Pathology, pathogenesis and therapy of growth hormone (GH)-producing pituitary adenomas: technical advances in histochemistry and th eir contribution. (PubMed id 19759870)⁹ Osamura R.Y....Teramoto A. (2009)
229. Genetic forms of hypopituitarism and their manifestat ion in the neonatal period. (PubMed id 19762173)⁹ Alatzoglou K.S. and Dattani M.T. (2009)
230. Role of transcription factors in midline central nervous system and pituitary defects. (PubMed id 19293576)⁹ Kelberman D. and Dattani M.T. (2009)
231. Laterality disturbance and hypopituitarism. A case report of co-existing situs inversus totalis and combined pituitary hormone deficiency. (PubMed id 18296909)⁹ HalA!sz Z....RA!cz K. (2008)
232. A novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiency. (PubMed id 18728160)⁹ Diaczok D....Radovick S. (2008)
233. ACTH and alpha-subunit are co-expressed in rare human pituitary corticotroph cell adenomas proposed to originate from ACTH-committed early pituitary progenitor cells. (PubMed id 18228160)⁹ Suzuki M....Osamura R.Y. (2008)
234. Mechanisms related to the pathophysiology and management of central hypothyroidism. (PubMed id 18941435)⁹ Yamada M. and Mori M. (2008)
235. Pituitary blastoma. (PubMed id 18551299)⁹ Scheithauer B.W....Kim O.L. (2008)
236. Developmental disorders of the hypothalamus and pituitary gland associated with congenital hypopituitarism. (PubMed id 18279788)⁹ Mehta A. and Dattani M.T. (2008)
237. Composite pituitary adenoma and craniopharyngioma?: an unusual sellar neoplasm with divergent differentiation. (PubMed id 18769335)⁹ Yoshida A....Rosenblum M.K. (2008)
238. GHRH proliferative action on somatotrophs is cell-type specific and dependent on Pit-1/GHF-1 expression. (PubMed id 17941086)⁹ Solloso A....Pombo C.M. (2008)
239. Regulation of growth hormone expression by Delta-like protein 1 (Dlk1). (PubMed id 17485162)⁹ Ansell P.J....Klibanski A. (2007)
240. MRI findings and genotype analysis in patients with childhood onset growth hormone deficiency--correlation with severity of hypopituitarism. (PubMed id 17642419)⁹ Zimmermann A....Bettendorf M. (2007)
241. Stromal cells of endometriosis fail to produce paracrine factors that induce epithelial 17beta-hydroxysteroid dehydrogenase type 2 gene and its transcriptional regulator Sp1: a mechanism for defective estradiol metabolism. (PubMed id 17403431)⁹ Cheng Y.H....Bulun S.E. (2007)
242. Essential role of GATA2 in the negative regulation of thyrotropin beta gene by thyroid hormone and its receptors. (PubMed id 17244762)⁹ Matsushita A....Nakamura H. (2007)
243. Expression of adrenocorticotropic hormone, prolactin and transcriptional factors in clinically nonfunctioning pituitary adenoma. (PubMed id 18079591)⁹ Kageyama K....Suda T. (2007)
244. Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway. (PubMed id 17412813)⁹ Dagvadorj A....Nevalainen M.T. (2007)
245. Hypothalamic and pituitary development: novel insights into the aetiology. (PubMed id 17785694)⁹ Kelberman D. and Dattani M.T. (2007)
246. Genetics of growth hormone deficiency. (PubMed id 17336732)⁹ Mullis P.E. (2007)
247. Panhypopituitarism: genetic versus acquired etiological factors. (PubMed id 17315526)⁹ Coya R....Martul P. (2007)
248. [Combined deficiency of TSH, GH, and PRL (PIT1 abnorm ality and PROP1 abnormality)] (PubMed id 16776098)⁹ Tatsumi K.I. (2006)
249. Long-term follow-up of combined pituitary hormone deficiency in two siblings with a Prophet of Pit-1 gene mutation. (PubMed id 17162714)⁹ Georgopoulos N.A....Panidis D. (2006)
250. Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. (PubMed id 16678101)⁹ Olson L.E....Rosenfeld M.G. (2006)
251. B29 gene silencing in pituitary cells is regulated by its 3' enhancer. (PubMed id 16920149)⁹ Malone C.S....Wall R. (2006)
252. Identification of transcriptional regulators of neuropeptide FF gene expression. (PubMed id 16515822)⁹ Nystedt J.M....Panula P. (2006)
253. A variation in a Pit-1 site in the growth hormone gene (GH1) promoter induces a differential transcriptional activity. (PubMed id 16517055)⁹ Giordano M....Momigliano-Richiardi P. (2006)
254. Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. (PubMed id 16968748)⁹ Sharp Z.D....Mancini M.A. (2006)
255. Fibroblast growth factor 2 and cyclic AMP synergistically regulate bone sialoprotein gene expression. (PubMed id 16466682)⁹ Shimizu E....Ogata Y. (2006)
256. Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. (PubMed id 16901921)⁹ Luque R.M....Kineman R.D. (2006)
257. Mutation analysis of POUF-1, PROP-1 and HESX-1 show low frequency of mutations in children with sporadic forms of combined pituitary hormone deficiency and septo-optic dysplasia. (PubMed id 15670191)⁹ Rainbow L.A....Kirk J.M. (2005)
258. EGF stimulates Pit-1 independent transcription of the human prolactin pituitary promoter in human breast cancer SK-BR-3 cells through its proximal AP-1 response element. (PubMed id 15607537)⁹ Manfroid I....Muller M. (2005)
259. Serine/threonine/tyrosine phosphorylation of the LHX3 LIM-homeodomain transcription factor. (PubMed id 15517599)⁹ Parker G.E....Rhodes S.J. (2005)
260. Menin and TGF-beta superfamily member signaling via the Smad pathway in pituitary, parathyroid and osteoblast. (PubMed id 16001330)⁹ Hendy G.N....Canaff L. (2005)
261. Stimulatory effect of interleukin-1beta on growth hormone gene expression and growth hormone release from rat GH3 cells. (PubMed id 16043966)⁹ Gong F.Y....Shi Y.F. (2005)
262. Recent progress in studies of pituitary tumor pathogenesis. (PubMed id 16311408)⁹ Minematsu T....Osamura R.Y. (2005)
263. Growth hormone deficiency and combined pituitary hormone deficiency: does the genotype matter? (PubMed id 16060904)⁹ Dattani M.T. (2005)
264. The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. (PubMed id 15618287)⁹ Ezzat S....Asa S.L. (2005)
265. Genetic basis of short stature. (PubMed id 16114273)⁹ Castro-Feijoo L....Pombo M. (2005)
266. Clinical and molecular features of a TSH-secreting pituitary microadenoma. (PubMed id 16379036)⁹ Usui T....Naruse M. (2005)
267. Molecular pathology of the pituitary. Development and functional differentiation of pituitary adenomas. (PubMed id 15281338)⁹ Osamura R.Y....Teramoto A. (2004)
268. Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein. (PubMed id 15246537)⁹ Guy J.C....Rhodes S.J. (2004)
269. Cooperative dimerization of the POU domain protein Brn-2 on a new motif activates the neuronal promoter of the human aromatic L-amino acid decarboxylase gene. (PubMed id 14741405)⁹ Dugast-Darzacq C....Weber M.J. (2004)
270. Pituitary hormone deficiencies due to transcription factor gene alterations. (PubMed id 15519252)⁹ Reynaud R....Brue T. (2004)
271. Familial combined pituitary hormone deficiency due to a novel mutation R99Q in the hot spot region of Prophet of Pit-1 presenting as constitutional growth delay. (PubMed id 12519826)⁹ Vieira T.C....Abucham J. (2003)
272. Identification of adrenocorticotropin receptor messenger ribonucleic acid in the human pituitary and its loss of expression in pituitary adenomas. (PubMed id 14671214)⁹ Morris D.G....Grossman A.B. (2003)
273. TCF and Groucho-related genes influence pituitary growth and development. (PubMed id 12907761)⁹ Brinkmeier M.L....Camper S.A. (2003)
274. Familial combined pituitary hormone deficiency caused by PROP-1 gene mutation. Growth patterns and MRI studies in untreated subjects. (PubMed id 12006708)⁹ Crone J....Frisch H. (2002)
275. Differential nuclear receptor signalling from DR4-type response elements. (PubMed id 12210766)⁹ Quack M....Carlberg C. (2002)
276. Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region. (PubMed id 11923475)⁹ Ozawa A.... Mori M. (2002)
277. Genetic defects in the development and function of the anterior pituitary gland. (PubMed id 12173688)⁹ Cushman L.J....Rhodes S.J. (2002)
278. A unique case of combined pituitary hormone deficienc y caused by a PROP1 gene mutation (R120C) associated with normal height and abs ent puberty. (PubMed id 12153609)⁹ Arroyo A....Mellon P.L. (2002)
279. Foetal and neonatal thyroid disorders. (PubMed id 12244277)⁹ Radetti G....Bona G. (2002)
280. [The mechanism of interferon-gamma increases growth hormone expression in rat pituitary GH(3) cells] (PubMed id 12198566)⁹ Gong F.Y....Deng J.Y. (2002)
281. A case of Cushing's disease caused by pituitary adenoma producing adrenocorticotropic hormone and growth hormone concomitantly: aberrant expression of transcription factors NeuroD1 and Pit-1 as a proposed mechanism. (PubMed id 12379758)⁹ Tahara S....Osamura R.Y. (2002)
282. Pseudotumor of the pituitary due to PROP-1 deletion. (PubMed id 11822586)⁹ Teinturier C....Bougneres P.F. (2002)
283. Differential activity by DNA-induced quarternary structures of POU transcription factors. (PubMed id 12213595)⁹ Remenyi A....Wilmanns M. (2002)
284. Cloning and characterization of the 5'-flanking region of the canine growth hormone gene. (PubMed id 12431806)⁹ Lantinga-van Leeuwen I.S....Mol J.A. (2002)
285. Isolated growth hormone deficiency in children and adolescents. (PubMed id 11529396)⁹ Argente J....Skordis N. (2001)
286. POU domain factors in the neuroendocrine system: less ons from developmental biology provide insights into human disease. (PubMed id 11159814)⁹ Andersen B. and Rosenfeld M.G. (2001)
287. Central hypothyroidism: consequences in adult life. (PubMed id 11964021)⁹ Asteria C....Beck-Peccoz P. (2001)
288. Inhibition of protein phosphatase PP1 in GH3B6, but not in GH3 cells, activates the MEK/ERK/c-fos pathway and the human prolactin promoter, involving the coactivator CPB/p300. (PubMed id 11266513)⁹ Manfroid I....Muller M. (2001)
289. A point mutation in the LIM domain of Lhx3 reduces activation of the glycoprotein hormone alpha-subunit promoter. (PubMed id 11279219)⁹ Howard P.W. and Maurer R.A. (2001)
290. Review: molecular thyroidology. (PubMed id 11508826)⁹ Winter W.E. and Signorino M.R. (2001)
291. Combined pituitary hormone deficiency and pituitary hypoplasia due to a mutation of the Pit-1 gene. (PubMed id 10792348)⁹ Frisch H....PfAoffle R. (2000)
292. Impaired adrenocorticotropin-adrenal axis in combined pituitary hormone deficiency caused by a two-base pair deletion (301-302delAG) in the prophet of Pit-1 gene. (PubMed id 10634415)⁹ Pernasetti F....Mellon P.L. (2000)
293. [Pituitary development and pathology of transcription factors] (PubMed id 10970945)⁹ Barlier A....Brue T. (2000)
294. MR imaging of the pituitary gland in children and young adults with congenital combined pituitary hormone deficiency associated with PROP1 mutations. (PubMed id 10658742)⁹ Fofanova O....Yamashita S. (2000)
295. Genetic regulation of the embryology of the pituitary gland and somatotrophs. (PubMed id 10905370)⁹ Cohen L.E. (2000)
296. Cloning, characterization, and physical mapping of the canine Prop-1 gene (PROP1): exclusion as a candidate for combined pituitary hormone deficiency in German shepherd dogs. (PubMed id 10773688)⁹ Lantinga-van Leeuwen I.S....van Oost B.A. (2000)
297. Biochemical and genetic characterization of the porci ne Prophet of Pit-1 pituitary transcription factor. (PubMed id 11064154)⁹ Sloop K.W....Rhodes S.J. (2000)
298. Central hypocortisolism as part of combined pituitary hormone deficiency due to mutations of PROP-1 gene. (PubMed id 11022176)⁹ Asteria C....Beck-Peccoz P. (2000)
299. The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. (PubMed id 10921928)⁹ Diamond S.E. and Gutierrez-Hartmann A. (2000)
300. cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes. (PubMed id 10931853)⁹ Hashimoto K....Wondisford F.E. (2000)
301. Functional significance of prop-1 gene expression in pituitary adenomas. (PubMed id 10890192)⁹ Usui T....Nakao K. (2000)
302. The molecular basis for developmental disorders of the pituitary gland in man. (PubMed id 10852367)⁹ Dattani M.T. and Robinson I.C. (2000)
303. Cloning and characterization of the 5'-flanking region of the human prolactin-releasing peptide receptor gene. (PubMed id 11027489)⁹ Kishimoto M....Chihara K. (2000)
304. Heritable disorders of pituitary development. (PubMed id 10599689)⁹ Parks J.S....Wajnrajch M.P. (1999)
305. Hypopituitarism in two brothers born by breech delivery. (PubMed id 15251687)⁹ del RincA^n J.P....Mutchinick O. (1999)
306. GH transcription factors. (PubMed id 10698595)⁹ Pfaffle R.W....Kentrup H. (1999)
307. A novel mechanism for cyclic adenosine 3',5'-monophosphate regulation of gene expression by CREB-binding protein. (PubMed id 9973256)⁹ Zanger K....Wondisford F.E. (1999)
308. Molecular basis of pituitary oncogenesis. (PubMed id 10728913)⁹ Tada M....Moriuchi T. (1999)
309. Gene analysis of PROP1 in dwarfism with combined pitu itary hormone deficiency. (PubMed id 10549300)⁹ Takamura N....Yamashita S. (1999)
310. Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain. (PubMed id 10369682)⁹ Tremblay J.J....Drouin J. (1999)
311. Human chromosome 3 and pig chromosome 13 show complete synteny conservation but extensive gene-order differences. (PubMed id 10449917)⁹ Sun H.F....Tuggle C.K. (1999)
312. Reverse transcription polymerase chain reaction analysis of pituitary hormone, Pit-1 and steroidogenic factor-1 messenger RNA expression in pituitary tumors. (PubMed id 11081157)⁹ McDermott M.T....Ridgway E.C. (1999)
313. Quantitative analysis of growth-related factors in human pituitary adenomas. Lowered insulin-like growth factor-I and its receptor mRNA in growth hormone-producing adenomas. (PubMed id 10498342)⁹ Otsuka F....Makino H. (1999)
314. DNase I hypersensitivity analysis of non-pituitary human prolactin gene expression. (PubMed id 10432232)⁹ Gaasenbeek M....DiMattia G.E. (1999)
315. Multifunctional role of the Pitx2 homeodomain protein C-terminal tail. (PubMed id 10490637)⁹ Amendt B.A....Russo A.F. (1999)
316. Pituitary hormones as neurotrophic signals: update on hypothalamic differentiation in genetic models of altered feedback. (PubMed id 10510245)⁹ Phelps C.J. and Hurley D.L. (1999)
317. Free alpha-subunit and intact TSH secretion in vitro are closely associated in human somatotroph adenomas. (PubMed id 9820613)⁹ Aylwin S.J....Burrin J.M. (1998)
318. Familial growth hormone deficiency associated with MRI abnormalities. (PubMed id 9805128)⁹ Hamilton J....Daneman D. (1998)
319. Phenotypic variability in familial combined pituitary hormone deficiency caused by a PROP1 gene mutation resulting in the substitution of Arg-->Cys at codon 120 (R120C). (PubMed id 9768691)⁹ Fluck C....Mullis P.E. (1998)
320. Selective inhibition of prolactin gene transcription by the ETS-2 repressor factor. (PubMed id 9822660)⁹ Day R.N....Elsholtz H.P. (1998)
321. Compound heterozygous deletion of the PROP-1 gene in children with combined pituitary hormone deficiency. (PubMed id 9661653)⁹ Fofanova O....Yamashita S. (1998)
322. How many homeobox genes does it take to make a pituitary gland? (PubMed id 9676531)⁹ Watkins-Chow D.E. and Camper S.A. (1998)
323. Visualization of Pit-1 transcription factor interacti ons in the living cell nucleus by fluorescence resonance energy transfer micros copy. (PubMed id 9731708)⁹ Day R.N. (1998)
324. Mutations in PROP1 cause familial combined pituitary hormone deficiency. (PubMed id 9462743)⁹ Wu W.... Rosenfeld M.G. (1998)
325. Clinical and molecular characterization of a Brazilia n patient with Pit-1 deficiency. (PubMed id 9829213)⁹ Arnhold I.J....Parks J.S. (1998)
326. A mutational hot spot in the Prop-1 gene in Russian children with combined pituitary hormone deficiency. (PubMed id 11081182)⁹ Fofanova O.V....Yamashita S. (1998)
327. [Congenital multiple anterior pituitary hormone deficiencies. An approach of pituitary ontogenesis] (PubMed id 9686002)⁹ Brue T....Enjalbert A. (1997)
328. Genomic organization and alternative splicing of human PACE4 (SPC4), kexin-like processing endoprotease. (PubMed id 9378725)⁹ Tsuji A.... Matsuda Y. (1997)
329. GH and TSH deficiency. (PubMed id 9439906)⁹ PfAoffle R.W....Heimann G. (1997)
330. Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation. (PubMed id 9147650)⁹ Gage P.J. and Camper S.A. (1997)
331. Pituitary stalk interruption syndrome: a clinical-biological-genetic assessment of its pathogenesis. (PubMed id 9329385)⁹ Pinto G....Brauner R. (1997)
332. A growth hormone-releasing hormone-producing pancreatic islet cell tumor metastasized to the pituitary is associated with pituitary somatotroph hyperplasia and acromegaly. (PubMed id 9253362)⁹ Sanno N....Kovacs K. (1997)
333. Induction of chinook salmon growth hormone promoter activity by the adenosine 3',5'-monophosphate (cAMP)-dependent pathway involves two cAMP-response elements with the CGTCA motif and the pituitary-specific transcription factor Pit-1. (PubMed id 8612514)⁹ Wong A.O....Hew C.L. (1996)
334. Pit-1: clinical aspects. (PubMed id 8805025)⁹ PfAoffle R....Parks J. (1996)
335. Determinants of thyrotrope-specific thyrotropin beta promoter activation. Cooperation of Pit-1 with another factor. (PubMed id 8550592)⁹ Haugen B.R....Ridgway E.C. (1996)
336. Genetic mapping of the human pituitary-specific transcriptional factor gene and its analysis in familial panhypopituitary dwarfism. (PubMed id 8931705)⁹ Raskin S....Phillips J.A. (1996)
337. CCAAT/enhancer-binding protein alpha activation of the rat growth hormone promoter in pituitary progenitor GHFT1-5 cells. (PubMed id 8702932)⁹ Schaufele F. (1996)
338. Mammosomatotroph adenoma causing gigantism in an 8-year old boy: a possible pathogenetic mechanism. (PubMed id 7621575)⁹ Dubuis J.M....Collu R. (1995)
339. The human gonadotropin-releasing hormone receptor gene: complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals. (PubMed id 7768323)⁹ Fan N.C....Leung P.C. (1995)
340. [Pituitary specific transcription factor Pit-1/GHF-1 and combined pituitary hormone deficiency] (PubMed id 8196186)⁹ Tatsumi K. (1994)
341. Gene organization of the mouse pro-hormone and pro-protein convertase PC1. (PubMed id 8011166)⁹ Ftouhi N....Seidah N.G. (1994)
342. [Molecular pathology of congenital pituitary hypothyroidism--discovery of new clinical entities] (PubMed id 8350517)⁹ Tatsumi K....Miyai K. (1993)
343. Congenital complete absence of GH, TSH and PRL in infants: a consequence of Pit-1 gene deletion. (PubMed id 7823001)⁹ Preeyasombat C....Choubtum L. (1993)
344. Effects of estrogen and epidermal growth factor on prolactin and Pit-1 mRNA in GH3 cells. (PubMed id 8424109)⁹ Zhang K....Lloyd R.V. (1993)
345. Specific cleavage of transcription factors by the thiol protease, m-calpain. (PubMed id 8255762)⁹ Watt F. and Molloy P.L. (1993)
346. Thyrotropin-releasing hormone and epidermal growth factor induce human prolactin expression via identical multiple cis elements. (PubMed id 8386115)⁹ Berwaer M....Martial J.A. (1993)
347. An AP-1-like factor and the pituitary-specific factor Pit-1 are both necessary to mediate hormonal induction of human thyrotropin beta gene expression. (PubMed id 8226861)⁹ Kim M.K....Weintraub B.D. (1993)
348. Pit-1 and Pit-2 role in growth hormone gene regulation. (PubMed id 7920986)⁹ Vila V....Castrillo J.L. (1993)
349. Okadaic acid, a protein phosphatase inhibitor, enhances transcription of a receptor gene containing sequence A of the human prolactin promoter. (PubMed id 8232316)⁹ Wera S....Martial J.A. (1993)
350. Immunohistochemical analysis of GH-producing adenomas--with special emphasis on plurihormonality of individual tumor cells by double staining. (PubMed id 1285309)⁹ Inada K....Osamura R.Y. (1992)
351. The effect of 'binge' ethanol exposure on growth hormone and prolactin gene expression and secretion. (PubMed id 1330488)⁹ Emanuele M.A....Kelley M.R. (1992)
352. Activin inhibits binding of transcription factor Pit-1 to the growth hormone promoter. (PubMed id 1454833)⁹ Struthers R.S....Vale W.W. (1992)
353. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. (PubMed id 1495986)⁹ Lai J.S. and Herr W. (1992)
354. POU proteins bend DNA via the POU-specific domain. (PubMed id 1915275)⁹ Verrijzer C.P....van der Vliet P.C. (1991)

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