Free for academic non-profit institutions. Other users need a Commercial license

Aliases for POTEJ Gene

Aliases for POTEJ Gene

  • POTE Ankyrin Domain Family, Member J 2 3
  • POTE Ankyrin Domain Family Member J 3
  • POTE2beta 3

External Ids for POTEJ Gene

Previous GeneCards Identifiers for POTEJ Gene

  • GC00U926668
  • GC02P131370

Summaries for POTEJ Gene

GeneCards Summary for POTEJ Gene

POTEJ (POTE Ankyrin Domain Family, Member J) is a Protein Coding gene. An important paralog of this gene is ANKRD18A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEJ Gene

Genomics for POTEJ Gene

Genomic Location for POTEJ Gene

130,611,481 bp from pter
130,658,091 bp from pter
46,611 bases
Plus strand

Genomic View for POTEJ Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for POTEJ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEJ Gene

No data available for Regulatory Elements for POTEJ Gene

Proteins for POTEJ Gene

  • Protein details for POTEJ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member J
    Protein Accession:
    Secondary Accessions:

    Protein attributes for POTEJ Gene

    1038 amino acids
    Molecular mass:
    117390 Da
    Quaternary structure:
    No Data Available

neXtProt entry for POTEJ Gene

Proteomics data for POTEJ Gene at MOPED

Post-translational modifications for POTEJ Gene

  • Ubiquitination at Lys747 and Lys876
  • Modification sites at PhosphoSitePlus

Other Protein References for POTEJ Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for POTEJ Gene

Domains for POTEJ Gene

Protein Domains for POTEJ Gene

Suggested Antigen Peptide Sequences for POTEJ Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • In the N-terminal section; belongs to the POTE family.
  • Contains 5 ANK repeats.
  • In the N-terminal section; belongs to the POTE family.
  • In the C-terminal section; belongs to the actin family.
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with POTEJ: view

Function for POTEJ Gene

Gene Ontology (GO) - Molecular Function for POTEJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with POTEJ: view

Animal Model Products

CRISPR Products

miRNA for POTEJ Gene

miRTarBase miRNAs that target POTEJ

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for POTEJ Gene

Localization for POTEJ Gene

Subcellular locations from

Jensen Localization Image for POTEJ Gene COMPARTMENTS Subcellular localization image for POTEJ gene
Compartment Confidence
cytoskeleton 3
cytosol 3
golgi apparatus 3
nucleus 3
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for POTEJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
GO:0070062 extracellular exosome IDA 23533145
genes like me logo Genes that share ontologies with POTEJ: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for POTEJ Gene

Pathways for POTEJ Gene

SuperPathways for POTEJ Gene

No Data Available

Gene Ontology (GO) - Biological Process for POTEJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis IEP 23580065
genes like me logo Genes that share ontologies with POTEJ: view

No data available for Pathways by source for POTEJ Gene

Transcripts for POTEJ Gene

mRNA/cDNA for POTEJ Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for POTEJ Gene

POTE ankyrin domain family, member J:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for POTEJ

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEJ Gene

No ASD Table

Relevant External Links for POTEJ Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for POTEJ Gene

mRNA expression in normal human tissues for POTEJ Gene

mRNA differential expression in normal tissues according to GTEx for POTEJ Gene

This gene is overexpressed in Testis (23.7), Prostate (7.4), Heart - Atrial Appendage (4.5), and Whole Blood (4.3).

Protein differential expression in normal tissues for POTEJ Gene

This gene is overexpressed in Heart (16.2), Brain (14.9), Skin (13.7), Saliva (10.8), and Lung (7.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for POTEJ Gene

SOURCE GeneReport for Unigene cluster for POTEJ Gene Hs.558829

genes like me logo Genes that share expressions with POTEJ: view

Expression partners for POTEJ Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for POTEJ Gene

Orthologs for POTEJ Gene

This gene was present in the common ancestor of chordates.

Orthologs for POTEJ Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 10 (a)
(Canis familiaris)
Mammalia -- 36
  • 8 (a)
-- 36
  • 38 (a)
-- 36
  • 13 (a)
-- 36
  • 11 (a)
-- 36
  • 10 (a)
-- 36
  • 10 (a)
-- 36
  • 37 (a)
-- 36
  • 41 (a)
(Mus musculus)
Mammalia Gm1758 36
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 8 (a)
(Pan troglodytes)
Mammalia -- 36
  • 93 (a)
(Gallus gallus)
Aves -- 36
  • 12 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 37 (a)
(Danio rerio)
Actinopterygii ANKRD7 36
  • 8 (a)
Species with no ortholog for POTEJ:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for POTEJ Gene

Gene Tree for POTEJ (if available)
Gene Tree for POTEJ (if available)

Paralogs for POTEJ Gene Pseudogenes for POTEJ Gene

genes like me logo Genes that share paralogs with POTEJ: view

Variants for POTEJ Gene

Sequence variations from dbSNP and Humsavar for POTEJ Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1837318 -- 130,627,185(-) TAAAC(A/G)TGCAT intron-variant
rs1839838 -- 130,638,280(-) AGGCT(C/T)AATGT intron-variant
rs2083274 -- 130,609,769(+) GCAGG(A/G)AAGAC upstream-variant-2KB
rs3872437 -- 130,626,782(-) TATGT(A/G)TTTCA intron-variant
rs62164882 -- 130,613,247(+) ATACA(C/T)ATATA intron-variant

Relevant External Links for POTEJ Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for POTEJ Gene

Disorders for POTEJ Gene

No disorders were found for POTEJ Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for POTEJ Gene

Publications for POTEJ Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  2. Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. (PMID: 16364570) Hahn Y. … Lee B. (Gene 2006) 2 3
  3. POTE paralogs are induced and differentially expressed in many cancers. (PMID: 16397215) Bera T.K. … Pastan I. (Cancer Res. 2006) 3
  4. Identification of a novel actin isoform in hepatocellular carcinoma. (PMID: 16824795) Chang K.-W. … Yeh C.-T. (Hepatol. Res. 2006) 3
  5. Evolution and expression of chimeric POTE-actin genes in the human genome. (PMID: 17101985) Lee Y. … Pastan I. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for POTEJ Gene

Sources for POTEJ Gene

Back to Top