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Aliases for POTEJ Gene

Aliases for POTEJ Gene

  • POTE Ankyrin Domain Family Member J 2 3 5
  • POTE Ankyrin Domain Family, Member J 2
  • POTE2beta 3

External Ids for POTEJ Gene

Previous GeneCards Identifiers for POTEJ Gene

  • GC00U926668
  • GC02P131370

Summaries for POTEJ Gene

GeneCards Summary for POTEJ Gene

POTEJ (POTE Ankyrin Domain Family Member J) is a Protein Coding gene. An important paralog of this gene is ACTB.

Additional gene information for POTEJ Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEJ Gene

Genomics for POTEJ Gene

Regulatory Elements for POTEJ Gene

Enhancers for POTEJ Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H130606 0.5 dbSUPER 0.7 -3.2 -3238 3.6 ZNF555 ZC3H11A ZNF781 LOC150776 FAR2P3 SMPD4 FAM168B POTEJ PIR60407
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around POTEJ on UCSC Golden Path with GeneCards custom track

Genomic Locations for POTEJ Gene

Genomic Locations for POTEJ Gene
47,036 bases
Plus strand

Genomic View for POTEJ Gene

Genes around POTEJ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POTEJ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POTEJ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEJ Gene

Proteins for POTEJ Gene

  • Protein details for POTEJ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member J
    Protein Accession:

    Protein attributes for POTEJ Gene

    1038 amino acids
    Molecular mass:
    117390 Da
    Quaternary structure:
    No Data Available

neXtProt entry for POTEJ Gene

Post-translational modifications for POTEJ Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for POTEJ Gene

No data available for DME Specific Peptides for POTEJ Gene

Domains & Families for POTEJ Gene

Gene Families for POTEJ Gene

Protein Domains for POTEJ Gene

Suggested Antigen Peptide Sequences for POTEJ Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • In the N-terminal section; belongs to the POTE family.
  • In the N-terminal section; belongs to the POTE family.
  • In the C-terminal section; belongs to the actin family.
genes like me logo Genes that share domains with POTEJ: view

Function for POTEJ Gene

Animal Model Products

miRNA for POTEJ Gene

miRTarBase miRNAs that target POTEJ

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for POTEJ Gene

Localization for POTEJ Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for POTEJ gene
Compartment Confidence
extracellular 5
nucleus 3
cytosol 3
golgi apparatus 2
plasma membrane 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for POTEJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
GO:0070062 extracellular exosome IDA 23533145
genes like me logo Genes that share ontologies with POTEJ: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for POTEJ Gene

Pathways & Interactions for POTEJ Gene

SuperPathways for POTEJ Gene

No Data Available

Gene Ontology (GO) - Biological Process for POTEJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis IEP 23580065
genes like me logo Genes that share ontologies with POTEJ: view

No data available for Pathways by source and SIGNOR curated interactions for POTEJ Gene

Drugs & Compounds for POTEJ Gene

No Compound Related Data Available

Transcripts for POTEJ Gene

mRNA/cDNA for POTEJ Gene

(5) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for POTEJ Gene

POTE ankyrin domain family, member J:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEJ Gene

No ASD Table

Relevant External Links for POTEJ Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for POTEJ Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for POTEJ Gene

mRNA differential expression in normal tissues according to GTEx for POTEJ Gene

This gene is overexpressed in Testis (x23.7), Prostate (x7.4), Heart - Atrial Appendage (x4.5), and Whole Blood (x4.3).

Protein differential expression in normal tissues from HIPED for POTEJ Gene

This gene is overexpressed in Heart (16.2), Brain (14.9), Skin (13.7), Saliva (10.8), and Lung (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for POTEJ Gene

Protein tissue co-expression partners for POTEJ Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of POTEJ Gene:


SOURCE GeneReport for Unigene cluster for POTEJ Gene:

genes like me logo Genes that share expression patterns with POTEJ: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for POTEJ Gene

Orthologs for POTEJ Gene

This gene was present in the common ancestor of chordates.

Orthologs for POTEJ Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 93 (a)
(Canis familiaris)
Mammalia -- 34
  • 41 (a)
-- 34
  • 38 (a)
-- 34
  • 37 (a)
-- 34
  • 13 (a)
-- 34
  • 11 (a)
-- 34
  • 10 (a)
-- 34
  • 10 (a)
-- 34
  • 8 (a)
(Mus musculus)
Mammalia Gm1758 34
  • 34 (a)
(Bos Taurus)
Mammalia -- 34
  • 10 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 8 (a)
(Gallus gallus)
Aves -- 34
  • 12 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 37 (a)
(Danio rerio)
Actinopterygii ANKRD7 34
  • 8 (a)
Species where no ortholog for POTEJ was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for POTEJ Gene

Gene Tree for POTEJ (if available)
Gene Tree for POTEJ (if available)

Paralogs for POTEJ Gene Pseudogenes for POTEJ Gene

genes like me logo Genes that share paralogs with POTEJ: view

Variants for POTEJ Gene

Sequence variations from dbSNP and Humsavar for POTEJ Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000305412 -- 130,654,459(+) GAACC(C/G)TGTTG intron-variant
rs1000566233 -- 130,658,312(+) ATTTT(C/G)TTTTA intron-variant, downstream-variant-500B, utr-variant-3-prime
rs1000626227 -- 130,655,938(+) GATAC(A/C)GATGT intron-variant
rs1000673038 -- 130,637,245(+) TTATT(A/C)TTTAA intron-variant
rs1000785402 -- 130,636,795(+) ACTTT(A/G)AAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for POTEJ Gene

Variant ID Type Subtype PubMed ID
nsv979263 CNV duplication 23825009
nsv963848 CNV duplication 23825009
nsv963847 CNV duplication 23825009
nsv962006 CNV duplication 23825009
nsv961510 CNV duplication 23825009
nsv953165 CNV duplication 24416366
nsv7327 OTHER inversion 18451855
nsv428403 CNV loss 18775914
nsv1152210 CNV duplication 26484159
nsv1148026 CNV duplication 26484159
nsv1147463 OTHER inversion 26484159
nsv1132510 CNV duplication 24896259
nsv1128813 CNV duplication 24896259
nsv1124813 CNV duplication 24896259
nsv1078469 CNV duplication 25765185
nsv1077892 CNV duplication 25765185
nsv1076496 CNV duplication 25765185
nsv10172 CNV loss 18304495
nsv1005664 CNV loss 25217958
esv3592455 CNV loss 21293372
esv3379519 CNV duplication 20981092
esv2760576 CNV gain+loss 21179565
esv2759092 CNV gain+loss 17122850
esv2720768 CNV deletion 23290073
esv2670824 CNV deletion 23128226
dgv4074n100 CNV gain 25217958
dgv2032n106 OTHER inversion 24896259

Variation tolerance for POTEJ Gene

Gene Damage Index Score: 7.35; 81.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for POTEJ Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POTEJ Gene

Disorders for POTEJ Gene

Relevant External Links for POTEJ

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for POTEJ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for POTEJ Gene

Publications for POTEJ Gene

  1. Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. (PMID: 16364570) Hahn Y … Lee B (Gene 2006) 2 3 60
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. (PMID: 24639526) Carmon KS … Liu Q (Proceedings of the National Academy of Sciences of the United States of America 2014) 3 60
  5. p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells. (PMID: 25331947) Veena MS … Srivatsan ES (The Journal of biological chemistry 2014) 3 60

Products for POTEJ Gene

Sources for POTEJ Gene

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