Free for academic non-profit institutions. Other users need a Commercial license

Aliases for POTEI Gene

Aliases for POTEI Gene

  • POTE Ankyrin Domain Family, Member I 2 3
  • POTE Ankyrin Domain Family Member I 3
  • POTE2beta 3

External Ids for POTEI Gene

Previous GeneCards Identifiers for POTEI Gene

  • GC02M131217

Summaries for POTEI Gene

GeneCards Summary for POTEI Gene

POTEI (POTE Ankyrin Domain Family, Member I) is a Protein Coding gene. An important paralog of this gene is POTEJ.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEI Gene

Genomics for POTEI Gene

Genomic Location for POTEI Gene

130,459,455 bp from pter
130,509,666 bp from pter
50,212 bases
Minus strand

Genomic View for POTEI Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for POTEI Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEI Gene

No data available for Regulatory Elements for POTEI Gene

Proteins for POTEI Gene

  • Protein details for POTEI Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member I
    Protein Accession:
    Secondary Accessions:

    Protein attributes for POTEI Gene

    1075 amino acids
    Molecular mass:
    121282 Da
    Quaternary structure:
    No Data Available

neXtProt entry for POTEI Gene

Proteomics data for POTEI Gene at MOPED

Post-translational modifications for POTEI Gene

  • Ubiquitination at Lys92, Lys784, and Lys913
  • Modification sites at PhosphoSitePlus

Other Protein References for POTEI Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for POTEI Gene

Domains for POTEI Gene

Gene Families for POTEI Gene

  • ANKRD :Ankyrin repeat domain containing
  • POTE :POTE ankyrin domain containing

Protein Domains for POTEI Gene

Suggested Antigen Peptide Sequences for POTEI Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • P0CG38
  • In the N-terminal section; belongs to the POTE family.
  • In the C-terminal section; belongs to the actin family.
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with POTEI: view

Function for POTEI Gene

Gene Ontology (GO) - Molecular Function for POTEI Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with POTEI: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for POTEI

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for POTEI Gene

Localization for POTEI Gene

Subcellular locations from

Jensen Localization Image for POTEI Gene COMPARTMENTS Subcellular localization image for POTEI gene
Compartment Confidence
cytosol 4
extracellular 4
cytoskeleton 2
golgi apparatus 2
nucleus 2
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for POTEI Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
GO:0070062 extracellular exosome IDA 23533145
genes like me logo Genes that share ontologies with POTEI: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for POTEI Gene

Pathways for POTEI Gene

SuperPathways for POTEI Gene

No Data Available

Gene Ontology (GO) - Biological Process for POTEI Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis IEP 23580065
genes like me logo Genes that share ontologies with POTEI: view

No data available for Pathways by source for POTEI Gene

Transcripts for POTEI Gene

mRNA/cDNA for POTEI Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for POTEI Gene

POTE ankyrin domain family, member I:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for POTEI

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEI Gene

No ASD Table

Relevant External Links for POTEI Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for POTEI Gene

mRNA expression in normal human tissues for POTEI Gene

mRNA differential expression in normal tissues according to GTEx for POTEI Gene

This gene is overexpressed in Testis (28.5), Prostate (7.7), and Heart - Atrial Appendage (5.5).

Protein differential expression in normal tissues for POTEI Gene

This gene is overexpressed in Spleen (19.0), Skin (11.7), Brain (11.2), Heart (8.8), Lung (8.0), and Saliva (6.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for POTEI Gene

SOURCE GeneReport for Unigene cluster for POTEI Gene Hs.558782

genes like me logo Genes that share expressions with POTEI: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for POTEI Gene

Orthologs for POTEI Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for POTEI Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia POTEI 35
  • 98.39 (n)
  • 97.02 (a)
-- 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Potef 35
  • 85.6 (n)
  • 90.67 (a)
(Bos Taurus)
Mammalia -- 36
  • 10 (a)
(Canis familiaris)
Mammalia -- 36
  • 8 (a)
-- 36
  • 38 (a)
-- 36
  • 13 (a)
-- 36
  • 11 (a)
-- 36
  • 10 (a)
-- 36
  • 10 (a)
-- 36
  • 37 (a)
-- 36
  • 41 (a)
(Mus musculus)
Mammalia Gm1758 36
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 8 (a)
(Gallus gallus)
Aves LOC776816 35
  • 86.13 (n)
  • 90.67 (a)
-- 36
  • 12 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 37 (a)
(Danio rerio)
Actinopterygii ANKRD7 36
  • 8 (a)
fruit fly
(Drosophila melanogaster)
Insecta Act42A 35
  • 80.04 (n)
  • 89.04 (a)
(Caenorhabditis elegans)
Secernentea act-5 35
  • 77.6 (n)
  • 85.33 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons ACT11 35
  • 72.56 (n)
  • 82.84 (a)
(Oryza sativa)
Liliopsida Os05g0106600 35
  • 73.91 (n)
  • 82.57 (a)
Species with no ortholog for POTEI:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for POTEI Gene

Gene Tree for POTEI (if available)
Gene Tree for POTEI (if available)

Paralogs for POTEI Gene Pseudogenes for POTEI Gene

genes like me logo Genes that share paralogs with POTEI: view

Variants for POTEI Gene

Sequence variations from dbSNP and Humsavar for POTEI Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1814429 -- 130,491,595(+) ACAAT(C/G)TCTTC intron-variant
rs1814430 -- 130,491,632(+) GATTC(A/G)GACAT intron-variant
rs1816690 -- 130,491,627(+) TCCAC(G/T)ATTCA intron-variant
rs1816691 -- 130,491,637(+) AGACA(C/T)ATTTA intron-variant
rs1816692 -- 130,491,816(+) tgccc(A/T)gctaa intron-variant

Relevant External Links for POTEI Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for POTEI Gene

Disorders for POTEI Gene

No disorders were found for POTEI Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for POTEI Gene

Publications for POTEI Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  2. Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. (PMID: 16364570) Hahn Y. … Lee B. (Gene 2006) 2 3
  3. Identification of a novel actin isoform in hepatocellular carcinoma. (PMID: 16824795) Chang K.-W. … Yeh C.-T. (Hepatol. Res. 2006) 3
  4. HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells. (PMID: 17342744) Dall'Era M.A. … Liu A.Y. (Prostate 2007) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for POTEI Gene

Sources for POTEI Gene

Back to Top