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Aliases for POTEG Gene

Aliases for POTEG Gene

  • POTE Ankyrin Domain Family Member G 2 3 5
  • Prostate, Ovary, Testis-Expressed Protein On Chromosome 14 3 4
  • Cancer/Testis Antigen Family 104, Member 4 2 3
  • ANKRD26-Like Family C Member 2 3 4
  • POTE-14 3 4
  • POTE14 3 4
  • A26C2 3 4
  • Protein Expressed In Prostate, Ovary, Testis, And Placenta 14 3
  • POTE Ankyrin Domain Family, Member G 2
  • ANKRD26-Like Family C, Member 2 2
  • POTE14alpha 3
  • CT104.4 3
  • ACTBL1 3
  • POTE22 3

External Ids for POTEG Gene

Previous HGNC Symbols for POTEG Gene

  • A26C2

Previous GeneCards Identifiers for POTEG Gene

  • GC14P018628
  • GC14P019554

Summaries for POTEG Gene

GeneCards Summary for POTEG Gene

POTEG (POTE Ankyrin Domain Family Member G) is a Protein Coding gene. An important paralog of this gene is POTEM.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEG Gene

Genomics for POTEG Gene

Genomic Location for POTEG Gene

Chromosome:
14
Start:
19,402,486 bp from pter
End:
19,434,341 bp from pter
Size:
31,856 bases
Orientation:
Minus strand

Genomic View for POTEG Gene

Genes around POTEG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POTEG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POTEG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEG Gene

Proteins for POTEG Gene

  • Protein details for POTEG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6S5H5-POTEG_HUMAN
    Recommended name:
    POTE ankyrin domain family member G
    Protein Accession:
    Q6S5H5
    Secondary Accessions:
    • A1L153
    • A6NMI9
    • Q6S5H6
    • Q6S8J2

    Protein attributes for POTEG Gene

    Size:
    508 amino acids
    Molecular mass:
    57096 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAS58870.1; Type=Frameshift; Positions=308; Evidence={ECO:0000305};

    Alternative splice isoforms for POTEG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for POTEG Gene

Post-translational modifications for POTEG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for POTEG Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for POTEG Gene

Domains & Families for POTEG Gene

Protein Domains for POTEG Gene

Suggested Antigen Peptide Sequences for POTEG Gene

Graphical View of Domain Structure for InterPro Entry

Q6S5H5

UniProtKB/Swiss-Prot:

POTEG_HUMAN :
  • Belongs to the POTE family.
  • Contains 5 ANK repeats.
Family:
  • Belongs to the POTE family.
Similarity:
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with POTEG: view

Function for POTEG Gene

genes like me logo Genes that share phenotypes with POTEG: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for POTEG Gene

Localization for POTEG Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for POTEG Gene COMPARTMENTS Subcellular localization image for POTEG gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for POTEG Gene

Pathways & Interactions for POTEG Gene

SuperPathways for POTEG Gene

No Data Available

Interacting Proteins for POTEG Gene

Gene Ontology (GO) - Biological Process for POTEG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for POTEG Gene

Transcripts for POTEG Gene

Unigene Clusters for POTEG Gene

POTE ankyrin domain family, member G:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEG Gene

No ASD Table

Relevant External Links for POTEG Gene

GeneLoc Exon Structure for
POTEG
ECgene alternative splicing isoforms for
POTEG

Expression for POTEG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for POTEG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for POTEG Gene

This gene is overexpressed in Prostate (x30.6) and Testis (x20.6).

Protein differential expression in normal tissues from HIPED for POTEG Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for POTEG Gene



Protein tissue co-expression partners for POTEG Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of POTEG Gene:

POTEG

SOURCE GeneReport for Unigene cluster for POTEG Gene:

Hs.711826
genes like me logo Genes that share expression patterns with POTEG: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for POTEG Gene

Orthologs for POTEG Gene

This gene was present in the common ancestor of chordates.

Orthologs for POTEG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 84 (a)
ManyToMany
-- 35
  • 80 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 42 (a)
ManyToMany
-- 35
  • 38 (a)
ManyToMany
-- 35
  • 36 (a)
ManyToMany
-- 35
  • 11 (a)
ManyToMany
-- 35
  • 7 (a)
ManyToMany
-- 35
  • 6 (a)
ManyToMany
-- 35
  • 2 (a)
ManyToMany
-- 35
ManyToMany
mouse
(Mus musculus)
Mammalia Gm1758 35
  • 33 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 4 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 35
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 8 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 36 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii ANKRD7 35
  • 5 (a)
OneToMany
Species where no ortholog for POTEG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for POTEG Gene

ENSEMBL:
Gene Tree for POTEG (if available)
TreeFam:
Gene Tree for POTEG (if available)

Paralogs for POTEG Gene

Variants for POTEG Gene

Sequence variations from dbSNP and Humsavar for POTEG Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10154340 -- 19,419,297(+) tgttt(G/T)cttac intron-variant, upstream-variant-2KB
rs10154413 -- 19,407,303(+) tatac(A/G)tatGT intron-variant
rs10154547 -- 19,421,226(+) ctcca(C/G)tcaga intron-variant, nc-transcript-variant
rs10154570 -- 19,408,545(+) TTTAC(C/T)ACCCt intron-variant
rs10212072 -- 19,405,881(+) TCCCT(C/T)TTACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for POTEG Gene

Variant ID Type Subtype PubMed ID
dgv1182e59 CNV duplication 20981092
dgv1183e59 CNV duplication 20981092
dgv1184e59 CNV duplication 20981092
dgv1185e59 CNV duplication 20981092
dgv1186e59 CNV duplication 20981092
dgv1752n100 CNV gain 25217958
dgv1753n100 CNV gain 25217958
dgv1756n100 CNV loss 25217958
dgv1757n100 CNV gain 25217958
dgv1759n100 CNV gain 25217958
dgv1760n100 CNV gain+loss 25217958
dgv1761n100 CNV gain+loss 25217958
dgv1762n100 CNV loss 25217958
dgv1763n100 CNV gain 25217958
dgv1764n100 CNV loss 25217958
dgv1765n100 CNV gain+loss 25217958
dgv1766n100 CNV gain 25217958
dgv1767n100 CNV loss 25217958
dgv1768n100 CNV gain 25217958
dgv1769n100 CNV gain 25217958
dgv1770n100 CNV gain+loss 25217958
dgv1771n100 CNV loss 25217958
dgv1772n100 CNV gain 25217958
dgv33e203 CNV gain+loss 21179565
dgv3489n54 CNV gain 21841781
dgv3494n54 CNV loss 21841781
dgv3512n54 CNV loss 21841781
dgv3513n54 CNV loss 21841781
dgv3514n54 CNV loss 21841781
dgv3515n54 CNV loss 21841781
dgv45e180 CNV loss 20482838
dgv86n111 CNV duplication 26073780
esv1005804 OTHER inversion 20482838
esv23873 CNV gain+loss 19812545
esv2748433 CNV deletion 23290073
esv2759971 CNV gain+loss 17122850
esv3329783 CNV duplication 20981092
esv33527 CNV gain+loss 17666407
esv3362070 CNV duplication 20981092
esv3366979 CNV duplication 20981092
esv3377586 CNV duplication 20981092
esv3381124 CNV duplication 20981092
esv3584743 CNV gain 24956385
esv3892461 CNV gain 25118596
esv3892464 CNV gain 25118596
nsv1037353 CNV gain 25217958
nsv1044659 CNV gain 25217958
nsv1048150 CNV gain+loss 25217958
nsv1048393 CNV gain+loss 25217958
nsv1070209 CNV deletion 25765185
nsv1075456 CNV duplication 25765185
nsv1076406 CNV duplication 25765185
nsv1076407 CNV duplication 25765185
nsv1110233 CNV duplication 24896259
nsv1110234 CNV duplication 24896259
nsv1110856 OTHER inversion 24896259
nsv1118532 CNV duplication 24896259
nsv1141242 CNV duplication 24896259
nsv1141243 CNV duplication 24896259
nsv1147454 CNV duplication 26484159
nsv1150196 CNV duplication 26484159
nsv1160152 CNV duplication 26073780
nsv1160154 CNV duplication 26073780
nsv428292 CNV gain+loss 18775914
nsv433422 CNV gain 18776910
nsv436829 CNV insertion 17901297
nsv509526 CNV insertion 20534489
nsv563705 CNV loss 21841781
nsv563729 CNV loss 21841781
nsv7248 OTHER inversion 18451855
nsv819711 CNV loss 19587683
nsv832732 CNV loss 17160897
nsv9117 CNV gain+loss 18304495
nsv951957 CNV duplication 24416366
nsv974303 CNV duplication 23825009
nsv983886 CNV duplication 23825009

Variation tolerance for POTEG Gene

Gene Damage Index Score: 8.49; 85.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for POTEG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
POTEG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POTEG Gene

Disorders for POTEG Gene

Relevant External Links for POTEG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
POTEG

No disorders were found for POTEG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for POTEG Gene

Publications for POTEG Gene

  1. Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. (PMID: 15276201) Bera T.K. … Pastan I. (Gene 2004) 3 4 64
  2. Identification of a novel actin isoform in hepatocellular carcinoma. (PMID: 16824795) Chang K.-W. … Yeh C.-T. (Hepatol. Res. 2006) 3 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for POTEG Gene

Sources for POTEG Gene

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