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Aliases for POTEE Gene

Aliases for POTEE Gene

  • POTE Ankyrin Domain Family, Member E 2 3
  • POTE2 3 4 6
  • Prostate, Ovary, Testis-Expressed Protein On Chromosome 2 3 4
  • ANKRD26-Like Family C, Member 1A 2 3
  • ANKRD26-Like Family C Member 1A 3 4
  • A26C1A 3 4
  • POTE-2 3 4
  • Protein Expressed In Prostate, Ovary, Testis, And Placenta 2 3
  • Cancer/Testis Antigen Family 104, Member 2 3
  • POTE Ankyrin Domain Family Member E 3
  • Cancer/Testis Antigen Family 104 2
  • POTE2gamma 3
  • Member 2 2
  • CT104.2 3
  • A26C1 3

External Ids for POTEE Gene

Previous HGNC Symbols for POTEE Gene

  • A26C1A

Previous GeneCards Identifiers for POTEE Gene

  • GC02P131695
  • GC02P131980
  • GC02M123138

Summaries for POTEE Gene

GeneCards Summary for POTEE Gene

POTEE (POTE Ankyrin Domain Family, Member E) is a Protein Coding gene. An important paralog of this gene is POTEJ.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEE Gene

Genomics for POTEE Gene

Regulatory Elements for POTEE Gene

Genomic Location for POTEE Gene

131,218,067 bp from pter
131,265,448 bp from pter
47,382 bases
Plus strand

Genomic View for POTEE Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for POTEE Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEE Gene

Proteins for POTEE Gene

  • Protein details for POTEE Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member E
    Protein Accession:
    Secondary Accessions:
    • Q6S8J4
    • Q6S8J5
    • Q6S8J8

    Protein attributes for POTEE Gene

    1075 amino acids
    Molecular mass:
    121363 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for POTEE Gene


neXtProt entry for POTEE Gene

Proteomics data for POTEE Gene at MOPED

Post-translational modifications for POTEE Gene

  • Ubiquitination at Lys55, Lys92, Lys114, Lys116, Lys142, Lys684, Lys784, Lys913, and Lys915
  • Modification sites at PhosphoSitePlus

Other Protein References for POTEE Gene

No data available for DME Specific Peptides for POTEE Gene

Domains for POTEE Gene

Protein Domains for POTEE Gene

Suggested Antigen Peptide Sequences for POTEE Gene

Graphical View of Domain Structure for InterPro Entry



  • In the N-terminal section; belongs to the POTE family.
  • Contains 5 ANK repeats.
  • In the N-terminal section; belongs to the POTE family.
  • In the C-terminal section; belongs to the actin family.
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with POTEE: view

Function for POTEE Gene

Gene Ontology (GO) - Molecular Function for POTEE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with POTEE: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for POTEE Gene

Localization for POTEE Gene

Gene Ontology (GO) - Cellular Components for POTEE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
GO:0070062 extracellular exosome IDA 23533145
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with POTEE: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for POTEE Gene

Pathways for POTEE Gene

SuperPathways for POTEE Gene

No Data Available

Gene Ontology (GO) - Biological Process for POTEE Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis IEP 23580065
GO:0021762 substantia nigra development IEP 22926577
genes like me logo Genes that share ontologies with POTEE: view

No data available for Pathways by source for POTEE Gene

Transcripts for POTEE Gene

mRNA/cDNA for POTEE Gene

(6) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for POTEE Gene

POTE ankyrin domain family, member E:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for POTEE

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEE Gene

No ASD Table

Relevant External Links for POTEE Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for POTEE Gene

mRNA expression in normal human tissues for POTEE Gene

mRNA differential expression in normal tissues according to GTEx for POTEE Gene

This gene is overexpressed in Testis (31.7) and Prostate (6.2).

Protein differential expression in normal tissues for POTEE Gene

This gene is overexpressed in Skin (23.1), Saliva (16.5), Brain (12.1), and Lung (9.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for POTEE Gene

SOURCE GeneReport for Unigene cluster for POTEE Gene Hs.686146

genes like me logo Genes that share expressions with POTEE: view

Expression partners for POTEE Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for POTEE Gene

Orthologs for POTEE Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for POTEE Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia POTEF 35
  • 98.6 (n)
  • 97.67 (a)
-- 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC100361457 35
  • 85.69 (n)
  • 91.47 (a)
(Bos Taurus)
Mammalia -- 36
  • 10 (a)
(Canis familiaris)
Mammalia -- 36
  • 8 (a)
-- 36
  • 38 (a)
-- 36
  • 13 (a)
-- 36
  • 11 (a)
-- 36
  • 10 (a)
-- 36
  • 10 (a)
-- 36
  • 37 (a)
-- 36
  • 41 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 7 (a)
(Mus musculus)
Mammalia Gm20946 36
  • 25 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 8 (a)
(Gallus gallus)
Aves ACTBL2 35
  • 74.6 (n)
  • 86.63 (a)
-- 36
  • 12 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 37 (a)
(Danio rerio)
Actinopterygii zgc:86725 35
  • 78.79 (n)
  • 85.29 (a)
  • 8 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001676 35
  • 78.34 (n)
  • 85.03 (a)
fruit fly
(Drosophila melanogaster)
Insecta Act88F 35
  • 82.71 (n)
  • 89.57 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons ACT3 35
  • 73.01 (n)
  • 83.11 (a)
(Oryza sativa)
Liliopsida Os03g0836000 35
  • 73.28 (n)
  • 84.18 (a)
Species with no ortholog for POTEE:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for POTEE Gene

Gene Tree for POTEE (if available)
Gene Tree for POTEE (if available)

Paralogs for POTEE Gene Pseudogenes for POTEE Gene

genes like me logo Genes that share paralogs with POTEE: view

Variants for POTEE Gene

Sequence variations from dbSNP and Humsavar for POTEE Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs2073407 -- 131,228,277(-) CTTGC(C/T)GATCC reference, synonymous-codon
rs2407451 -- 131,228,753(+) ATAGT(C/G)CCCAG intron-variant
rs2579496 -- 131,228,800(+) ATGTT(C/T)ACTAC intron-variant
rs2672150 -- 131,264,111(-) GTCAG(G/T)CAGTT missense, reference
rs3868844 -- 131,225,084(-) ACCCA(C/T)ATGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for POTEE Gene

Variant ID Type Subtype PubMed ID
dgv1247e1 CNV Complex 17122850
nsv7327 OTHER Inversion 18451855
esv2670824 CNV Deletion 23128226
dgv659e201 CNV Deletion 23290073
dgv731e199 CNV Deletion 23128226
nsv524021 CNV Loss 19592680
dgv1252e1 CNV Complex 17122850
essv11772 CNV CNV 17122850
dgv1253e1 CNV Complex 17122850
dgv1254e1 CNV Complex 17122850
nsv428404 CNV Loss 18775914
dgv1255e1 CNV Complex 17122850
nsv10180 CNV Loss 18304495
dgv1256e1 CNV Complex 17122850
essv7904 CNV CNV 17122850
esv34412 CNV Gain 17911159
nsv875106 CNV Loss 21882294

Relevant External Links for POTEE Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POTEE Gene

Disorders for POTEE Gene

No disorders were found for POTEE Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for POTEE Gene

Publications for POTEE Gene

  1. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PMID: 17370265) Denis N.J. … Figeys D. (Proteomics 2007) 3 4
  2. Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. (PMID: 15276201) Bera T.K. … Pastan I. (Gene 2004) 3 4
  3. Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. (PMID: 16364570) Hahn Y. … Lee B. (Gene 2006) 3
  4. Identification of a novel actin isoform in hepatocellular carcinoma. (PMID: 16824795) Chang K.-W. … Yeh C.-T. (Hepatol. Res. 2006) 3
  5. Evolution and expression of chimeric POTE-actin genes in the human genome. (PMID: 17101985) Lee Y. … Pastan I. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3

Products for POTEE Gene

Sources for POTEE Gene

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