Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

POPDC3 Gene

protein-coding GIFtS: 48
GCID: GC06M105605

popeye domain containing 3

Explore 1 disease affiliated with
POPDC3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Popeye Domain Containing 3¹ ²		MGC22671¹
POP3¹ ² ³ ⁵		RP11-99L11.2²
BA355M14.1¹		Popeye Domain-Containing Protein 3²
Popeye Protein 3² ³

External Ids:	HGNC: 17649¹	Entrez Gene: 64208²	Ensembl: ENSG00000132429⁷	OMIM: 605824⁵	UniProtKB: Q9HBV1³

ORGUL members:
	NONCODE:n407041

Export aliases for POPDC3 gene to outside databases

Previous GC identifers: GC06M105651 GC06M105712 GC06M103048

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for POPDC3:

This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is

expressed in cardiac and skeletal muscle and may play an important role in these tissues during development.

Alternatively spliced transcript variants have been found. (provided by RefSeq, Nov 2008)

UniProtKB/Swiss-Prot: POPD3_HUMAN, Q9HBV1

Function: May play an important role in heart development

Gene Wiki entry for POPDC3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_025741.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the POPDC3 gene promoter:
Pbx1a ATF-2 HSF2 STAT3 Nkx2-5
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: POPDC3 promoter sequence

Search SABiosciences Chromatin IP Primers for POPDC3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POPDC3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q21 Ensembl cytogenetic band: 6q21 HGNC cytogenetic band: 6q21

POPDC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POPDC3 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M105605: view genomic region (about GC identifiers)

Start:	105,605,775 bp from pter	End:	105,627,870 bp from pter
Size:	22,096 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: POPD3_HUMAN, Q9HBV1 (See protein sequence)

Recommended Name: Popeye domain-containing protein 3

Size: 291 amino acids; 33870 Da

Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Secondary accessions: B2RA98 Q5T3Y8 Q8TBW6

Explore the universe of human proteins at neXtProt for POPDC3: NX_Q9HBV1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9HBV1

POPDC3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_071756.2

ENSEMBL proteins:

ENSP00000254765 ENSP00000414409

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: POPDC3 OriGene Custom Protein Services for POPDC3
	GenScript Custom Purified and Recombinant Proteins Services for POPDC3
	Novus Biologicals POPDC3 Protein Novus Biologicals POPDC3 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for POPDC3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	--	--
GO:0016021	integral to membrane	NAS	10882522

POPDC3 for ontologies About GeneDecksing

POPDC3 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for POPDC3
	GenScript Custom Superior Antibodies Services for POPDC3
	Novus Biologicals POPDC3 Antibody
	Search for Antibodies for POPDC3 at Abcam
	Uscn Antibodies for POPDC3
	Search ThermoFisher Antibodies for POPDC3

Assay Products for POPDC3:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for POPDC3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for POPDC3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

POPDC3 for domains About GeneDecksing

2 InterPro domains/families:

IPR018490 cNMP-bd-like

IPR006916 Popeye_prot

Graphical View of Domain Structure for InterPro Entry Q9HBV1

ProtoNet protein and cluster: Q9HBV1

UniProtKB/Swiss-Prot: POPD3_HUMAN, Q9HBV1

Similarity: Belongs to the popeye family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: POPD3_HUMAN, Q9HBV1

Function: May play an important role in heart development

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POPDC3
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate POPDC3:
		hsa-miR-3163 hsa-miR-340 hsa-miR-1272
		SwitchGear 3'UTR luciferase reporter plasmid: POPDC3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POPDC3 (see all 4) OriGene shRNA RFP: POPDC3 OriGene siRNA: POPDC3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POPDC3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for POPDC3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POPDC3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POPDC3 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: POPDC3 (NM_022361)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for POPDC3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POPDC3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for POPDC3
		Search LifeMap BioReagents cell lines for POPDC3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POPDC3

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

POPDC3 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for POPDC3:

G0/1 arrest

Increased G1 DNA content

Increased cell size

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for POPDC3

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

POPDC3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for POPDC3
Search CenterWatch for drugs/clinical trials and news about POPDC3 / POPD3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for POPDC3 gene:

NM_022361.4

Unigene Cluster for POPDC3:

Popeye domain containing 3

Hs.458336 [show with all ESTs]

Unigene Representative Sequence: NM_022361

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000254765(uc003pra.3 uc003prb.3) ENST00000489134 ENST00000474760

ENST00000429112

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POPDC3
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate POPDC3:
		hsa-miR-3163 hsa-miR-340 hsa-miR-1272
		SwitchGear 3'UTR luciferase reporter plasmid: POPDC3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POPDC3 (see all 4) OriGene shRNA RFP: POPDC3 OriGene siRNA: POPDC3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POPDC3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POPDC3 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POPDC3 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: POPDC3 (NM_022361)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for POPDC3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POPDC3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POPDC3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat POPDC3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POPDC3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POPDC3

Additional cDNA sequence:

AF204171.1 AK225989.1 AK314101.1 BC022323.2 NR_024539.1

6 DOTS entries:

DT.310711 DT.91712099 DT.100775199 DT.121384676 DT.95256618 DT.95355778

24/49 AceView cDNA sequences (see all 49):

BM721545 BC022323 CR591052 CB115856 CK824801 AA861832 BU156328 H84897

AW188117 BU627215 BE670789 CA433204 AF204171 NM_022361 BX332531 BX332532

BM800745 BQ005797 CK824800 BX501538 CK005752 BP369262 BM271790 BM264431

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for POPDC3 (see all 7) About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	·	5d	^	6a	·	6b	^	7a	·	7b	·	7c	·	7d
SP1:											-						-		-
SP2:					-		-		-		-						-		-
SP3:							-		-		-						-		-
SP4:
SP5:											-						-		-

ECgene alternative splicing isoforms for POPDC3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

POPDC3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

POPDC3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor E44 (Embryonic Progenitor Cell)

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See POPDC3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POPDC3

SOURCE GeneReport for Unigene cluster: Hs.458336

UniProtKB/Swiss-Prot: POPD3_HUMAN, Q9HBV1

Tissue specificity: Expressed predominantly in skeletal muscle and detected in heart

SABiosciences Custom PCR Arrays for POPDC3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POPDC3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat POPDC3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POPDC3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POPDC3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POPDC3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for POPDC3 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	POPDC3¹	popeye domain containing 3	76.09(n) 79.86(a)		395434 NM_204697.1 NP_990028.1
lizard (Anolis carolinensis)	Reptilia	POPDC3⁶	--	74(a)	1 ↔ 1	GL343430.1(618670-624542)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.19727²	Transcribed sequence with weak similarity to protein refNP_071756.1 (H.sapiens) popeye protein 3 [Homo sapiens] less	75.66(n)		AL960307.2
zebrafish (Danio rerio)	Actinopterygii	popdc3¹	popeye domain containing 3	65.13(n) 61.92(a)		415108 NM_001001848.1 NP_001001848.1
fruit fly (Drosophila melanogaster)	Insecta	bves⁶	bves	15(a)	1 → many	X(20924990-20953418)

ENSEMBL Gene Tree for POPDC3 (if available)
TreeFam Gene Tree for POPDC3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for POPDC3 gene

POPDC2² BVES²

2 SIMAP similar genes for POPDC3 using alignment to 2 protein entries: POPD3_HUMAN (see all proteins):

POPDC2 BVES

POPDC3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76661240^1,2	F,	--	105605281(+)	`CTAATT/GTATCA`	3	--	ds500¹ int¹		1		WA	118
rs146778342^1,2		--	105605483(+)	`GAACAC/TAGTCT`	3	--	ds500¹ int¹		0	--	--	--	--
rs58593121^1,2	F,	--	105605609(+)	`TTGTGC/TGGTGG`	3	--	int¹ ds500¹		1		EA	120
rs191638342^1,2		--	105605638(+)	`ACCCTC/TGCTGC`	3	--	ds500¹ int¹		0	--	--	--	--
rs11758394^1,2	H	--	105605656(+)	`CACCAC/ATGAAA`	3	--	ds500¹ int¹		4		NS EA	410
rs17065553^1,2	C,F,	--	105605677(+)	`CTGAAC/TACGTG`	3	--	int¹ ds500¹		7		NA CSA WA EA	502
rs1190281^1,2	C,F,O,A,H,	--	105605865(+)	`TAGTCA/GCATCA`	3	--	ut3¹ nc-transcript-variantint¹ ese³		34		NS MN NA EA WA CSA	2962
rs10545196^1,2	C	--	105605887(+)	`ATTTAAAAT/- AAATA`	5	--	ut3¹ int¹ nc-transcript-variant		1		CSA	2
rs142753011^1,2	C,	--	105605887(+)	`ATTTA-/AAAT AAATA`	3	--	ut3¹ int¹ nc-transcript-variant		0	--	--	--	--
rs201657326^1,2	C	--	105605895(-)	`GCAATC/TATTTA`	3	--	ut3¹ nc-transcript-variantint¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for POPDC3 (105605775 - 105627870 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for POPDC3
2 CNVs: 3632 2650

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POPDC3

DNA2.0 Custom Variant and Variant Library Synthesis for POPDC3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

POPDC3 for disorders           About GeneDecksing

OMIM gene information: 605824    OMIM disorders: --

1 disease for POPDC3:    About MalaCards

multiple sclerosis

Human Genome Epidemiology (HuGE) Navigator: POPDC3 (5 documents)

Export disorders for POPDC3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for POPDC3 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with POPDC3)

Utopia: connect your pdf to the dynamic
world of online information

Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. (PubMed id 10882522)^{1, 2, 3, 9} Andree B.... Brand T. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Reduced Popdc3 expression correlates with high risk an d poor survival in patients with gastric cancer. (PubMed id 22654436)¹ Luo D....Luo J.B. (2012)
Genome-wide association study of severity in multiple sclerosis. (PubMed id 21654844)¹ ....De Jager P.L. (2011)
The role of height-associated loci identified in geno me wide association studies in the determination of pediatric stature. (PubMed id 20546612)¹ Zhao J....Grant S.F. (2010)
Frequent silencing of popeye domain-containing genes, BVES and POPDC3, is associated with promoter hypermethylation in gastric cance r. (PubMed id 20627872)¹ Kim M....Kim Y.S. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
Genome-wide association study identifies sequence var iants on 6q21 associated with age at menarche. (PubMed id 19448622)¹ Sulem P....Stefansson K. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 64208	HGNC: 17649	AceView: POPDC3	Ensembl:ENSG00000132429	euGenes: HUgn64208
ECgene: POPDC3	H-InvDB: POPDC3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for POPDC3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for POPDC3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for POPDC3 gene:
Search GeneIP for patents involving POPDC3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for POPDC3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POPDC3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POPDC3
	OriGene Protein Over-expression Lysate for POPDC3		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for POPDC3		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POPDC3		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POPDC3
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for POPDC3		OriGene Custom Protein Services for POPDC3
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POPDC3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POPDC3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POPDC3
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POPDC3
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POPDC3
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POPDC3

	GenScript Custom Purified and Recombinant Proteins Services for POPDC3		GenScript cDNA clones with any tag delivered in your preferred vector for POPDC3
	GenScript Custom Assay Services for POPDC3		GenScript Custom Superior Antibodies Services for POPDC3
	GenScript Custom overexpressing Cell Line Services for POPDC3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in POPDC3 promoter
	Search Chromatin IP Primers for POPDC3
	RT² qPCR Primer Assay in human, mouse, rat POPDC3
	Search GNC Networks for POPDC3
	SABiosciences Custom PCR Arrays for POPDC3

Search Tocris compounds for POPDC3

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	POPDC3 antibodies
	POPDC3 proteins
	POPDC3 lysates

	Search for Antibodies for POPDC3 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for POPDC3
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

POPDC3 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for POPDC3

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POPDC3

	SwitchGear 3'UTR luciferase reporter plasmids for POPDC3
	SwitchGear Promoter luciferase reporter plasmids for POPDC3

Search ThermoFisher Antibodies for POPDC3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POPDC3

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes POPDC3 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

POPDC3 Gene

popeye domain containing 3

Aliases
for POPDC3 gene

Summaries
for POPDC3 gene

Genomic Views
for POPDC3 gene

Proteins
for POPDC3 gene

Protein Domains /
Families
for POPDC3 gene

Function
for POPDC3 gene

Pathways & Interactions
for POPDC3 gene

Drugs & Compounds
for POPDC3 gene

Transcripts
for POPDC3 gene

Expression
for POPDC3 gene

Orthologs
for POPDC3 gene

Paralogs
for POPDC3 gene

Genomic Variants
for POPDC3 gene

Disorders / Diseases
for POPDC3 gene

Publications
for POPDC3 gene

External Searches for POPDC3 gene

Genome Databases showing POPDC3 gene

Other Databases showing POPDC3 gene

Specialized Databases showing POPDC3 gene

Intellectual Property
for POPDC3 gene

Products
for POPDC3 gene

View Random Gene

Advanced Search

Export list of displayed genes

POPDC3 Gene

popeye domain containing 3

Aliasesfor POPDC3 gene

Summariesfor POPDC3 gene

Genomic Viewsfor POPDC3 gene

Proteinsfor POPDC3 gene

Protein Domains /Familiesfor POPDC3 gene

Functionfor POPDC3 gene

Pathways & Interactionsfor POPDC3 gene

Drugs & Compoundsfor POPDC3 gene

Transcriptsfor POPDC3 gene

Expression for POPDC3 gene

Orthologsfor POPDC3 gene

Paralogsfor POPDC3 gene

Genomic Variantsfor POPDC3 gene

Disorders / Diseasesfor POPDC3 gene

Publicationsfor POPDC3 gene

External Searches for POPDC3 gene

Genome Databases showing POPDC3 gene

Other Databases showing POPDC3 gene

Specialized Databases showing POPDC3 gene

Intellectual Propertyfor POPDC3 gene

Productsfor POPDC3 gene

View Random Gene

Aliases
for POPDC3 gene

Summaries
for POPDC3 gene

Genomic Views
for POPDC3 gene

Proteins
for POPDC3 gene

Protein Domains /
Families
for POPDC3 gene

Function
for POPDC3 gene

Pathways & Interactions
for POPDC3 gene

Drugs & Compounds
for POPDC3 gene

Transcripts
for POPDC3 gene

Expression
for POPDC3 gene

Orthologs
for POPDC3 gene

Paralogs
for POPDC3 gene

Genomic Variants
for POPDC3 gene

Disorders / Diseases
for POPDC3 gene

Publications
for POPDC3 gene

Intellectual Property
for POPDC3 gene

Products
for POPDC3 gene