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POPDC2 Gene

protein-coding   GIFtS: 54
GCID: GC03M119355

Popeye Domain Containing 2

  Search for POPDC2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Popeye Domain Containing 21 2
POP22 3 5
Popeye Protein 22 3
Popeye Domain-Containing Protein 22

External Ids:    HGNC: 176481   Entrez Gene: 640912   Ensembl: ENSG000001215777   OMIM: 6058235   UniProtKB: Q9HBU93   

Export aliases for POPDC2 gene to outside databases

Previous GC identifers: GC03M120643 GC03M120681 GC03M120843 GC03M116736


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for POPDC2 Gene:
This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This
membrane associated protein is predominantly expressed in skeletal and cardiac muscle, and may have an important
function in these tissues. (provided by RefSeq, Jul 2008)

GeneCards Summary for POPDC2 Gene:
POPDC2 (popeye domain containing 2) is a protein-coding gene. An important paralog of this gene is POPDC3.

UniProtKB/Swiss-Prot: POPD2_HUMAN, Q9HBU9
Function: May play an important role in heart development

Gene Wiki entry for POPDC2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the POPDC2 gene promoter:
         STAT1   Sp1   STAT1beta   RelA   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   STAT1alpha   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPOPDC2 promoter sequence
   Search Chromatin IP Primers for POPDC2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POPDC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.33   Ensembl cytogenetic band:  3q13.33   HGNC cytogenetic band: 3q13.33

POPDC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POPDC2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M119355:  view genomic region     (about GC identifiers)

Start:
119,355,304 bp from pter      End:
119,384,171 bp from pter
Size:
28,868 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: POPD2_HUMAN, Q9HBU9 (See protein sequence)
Recommended Name: Popeye domain-containing protein 2  
Size: 364 amino acids; 40448 Da
Sequence caution: Sequence=AAH26911.1; Type=Erroneous initiation;
Secondary accessions: Q86UE7
Alternative splicing: 2 isoforms:  Q9HBU9-1   Q9HBU9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for POPDC2: NX_Q9HBU9

Explore proteomics data for POPDC2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn4
  • Modification sites at PhosphoSitePlus

  • See POPDC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071418.2  
    ENSEMBL proteins: 
     ENSP00000420795   ENSP00000340753   ENSP00000264231   ENSP00000417250   ENSP00000420715  
     ENSP00000438271  

    POPDC2 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for POPDC2
    OriGene Custom MassSpec
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    Novus Biologicals POPDC2 Protein
    Novus Biologicals POPDC2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for POPDC2

     
    Search eBioscience for Proteins for POPDC2 

    POPDC2 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of POPDC2
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    Abcam antibodies for POPDC2
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    ThermoFisher Antibody for POPDC2
    LSBio Antibodies in human, mouse, rat for POPDC2

    POPDC2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for POPDC2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for POPDC2
    Cloud-Clone Corp. CLIAs for POPDC2
    Search eBioscience for ELISAs for POPDC2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR018490 cNMP-bd-like
     IPR006916 Popeye_prot

    Graphical View of Domain Structure for InterPro Entry Q9HBU9

    ProtoNet protein and cluster: Q9HBU9

    UniProtKB/Swiss-Prot: POPD2_HUMAN, Q9HBU9
    Similarity: Belongs to the popeye family


    Find genes that share domains with POPDC2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: POPD2_HUMAN, Q9HBU9
    Function: May play an important role in heart development

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with POPDC2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for POPDC2:
     Decreased nuclei size in G2M 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Popdc2):
     cardiovascular system  growth/size/body  homeostasis/metabolism 

    Find genes that share phenotypes with POPDC2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POPDC2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for POPDC2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for POPDC2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for POPDC2

    miRNA
    Products:
        
    miRTarBase miRNAs that target POPDC2:
    hsa-mir-335-5p (MIRT017710)

    Block miRNA regulation of human, mouse, rat POPDC2 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate POPDC2:
    hsa-miR-411* hsa-miR-379*
    SwitchGear 3'UTR luciferase reporter plasmidPOPDC2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for POPDC2
    Predesigned siRNA for gene silencing in human, mouse, rat POPDC2

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for POPDC2

    Clone
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    OriGene ORF clones in mouse, rat for POPDC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: POPDC2 (NM_022135)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for POPDC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POPDC2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for POPDC2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POPDC2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    POPD2_HUMAN, Q9HBU9: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane NAS10882522

    Find genes that share ontologies with POPDC2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for POPDC2
    Interactions:

        Search GeneGlobe Interaction Network for POPDC2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for POPDC2 (Q9HBU92, 3 ENSP000002642314) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BTG2P785432, 3, ENSP000002905514MINT-6544482 I2D: score=1 STRING: ENSP00000290551
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with POPDC2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for POPDC2 (POPD2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for POPDC2 gene: 
    NM_022135.2  

    Unigene Cluster for POPDC2:

    Popeye domain containing 2
    Hs.656031  [show with all ESTs]
    Unigene Representative Sequence: AK124602
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000495362 ENST00000341124(uc010hqw.1) ENST00000264231(uc003ecx.1)
    ENST00000474523(uc003ecy.1) ENST00000493094 ENST00000468801 ENST00000468916
    ENST00000476092 ENST00000463323 ENST00000538678
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat POPDC2 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate POPDC2:
    hsa-miR-411* hsa-miR-379*
    SwitchGear 3'UTR luciferase reporter plasmidPOPDC2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for POPDC2
    Predesigned siRNA for gene silencing in human, mouse, rat POPDC2
    Clone
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    OriGene clones in human, mouse for POPDC2 (see all 6)
    OriGene ORF clones in mouse, rat for POPDC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: POPDC2 (NM_022135)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for POPDC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POPDC2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for POPDC2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat POPDC2
      QuantiTect SYBR Green Assays in human, mouse, rat POPDC2
      QuantiFast Probe-based Assays in human, mouse, rat POPDC2

    Additional mRNA sequence: 

    AF204173.1 AK124602.1 AK226022.1 AK314819.1 AK377174.1 BC026911.2 BC044929.1 

    9 DOTS entries:

    DT.95167023  DT.412864  DT.100709387  DT.86854326  DT.100764985  DT.120909378  DT.95290768  DT.100764983 
    DT.120909411 

    Selected AceView cDNA sequences (see all 267):

    F31554 N75018 AI361675 BQ267465 AI741753 BE644634 AW028042 BM828806 
    F30220 BM720367 BQ639694 AW204888 AW470042 W05763 AI093009 F26605 
    BX094462 AI418437 AA897414 BU783975 BM719827 AI453593 L77701 AW004609 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for POPDC2 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
    SP1:              -                                   -           -                     
    SP2:              -                                   -     -     -                     
    SP3:              -                                                                     
    SP4:              -     -                                                               
    SP5:                                                        -     -                     


    ECgene alternative splicing isoforms for POPDC2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    POPDC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCGTGGCACC
    POPDC2 Expression
    About this image


    POPDC2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Heart (Cardiovascular System)
             Cardiomyocyte-like progenitor cells
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     NULL (Uncategorized)
             DKK1-induced cells
    POPDC2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    POPDC2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656031

    UniProtKB/Swiss-Prot: POPD2_HUMAN, Q9HBU9
    Tissue specificity: Expressed predominantly in the heart, and is also detected in the skeletal muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POPDC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for POPDC2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Popdc21 , 5 popeye domain containing 21, 5 81.51(n)1
    79.89(a)1
      16 (26.79 cM)5
    640821  NM_001081984.11  NP_001075453.11 
     383622095 
    chicken
    (Gallus gallus)
    Aves POPDC21 popeye domain containing 2 70.13(n)
    65.75(a)
      404229  NM_206865.1  NP_996747.1 
    lizard
    (Anolis carolinensis)
    Reptilia POPDC26
    popeye domain containing 2
    57(a)
    1 ↔ 1
    GL343414.1(176674-200110)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.105932 Xenopus laevis transcribed sequences 71.67(n)    BX844321.1 
    zebrafish
    (Danio rerio)
    Actinopterygii popdc21 popeye domain containing 2 59.16(n)
    58.2(a)
      793666  NM_001020800.1  NP_001018636.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bves6
    bves
    18(a)
    1 → many
    X(20924990-20953418)


    ENSEMBL Gene Tree for POPDC2 (if available)
    TreeFam Gene Tree for POPDC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for POPDC2 gene
    POPDC32  BVES2  
    2 SIMAP similar genes for POPDC2 using alignment to 3 protein entries:     POPD2_HUMAN (see all proteins):
    POPDC3    BVES

    Find genes that share paralogs with POPDC2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for POPDC2 (see all 498)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs356877261,2
    C--119344919(+) TTTTT-/T/TTT 
            
    CTTGG
    1 -- int11NA 2
    rs1844213621,2
    --119360451(+) CTGACA/TGAAAC 1 -- int10--------
    rs759852241,2
    C--119360534(+) TATTAA/GGACAA 1 -- int10--------
    rs46878691,2
    C,F--119360621(+) AAGGAA/CAATAG 1 -- int18Minor allele frequency- C:0.28NA WA CSA EA 370
    rs347878811,2
    C,F--119360651(+) TCTACT/CTTAAG 1 -- int19Minor allele frequency- C:0.23NA WA CSA EA 372
    rs1455901801,2
    --119360710(+) ACTATC/TGTTTA 1 -- int10--------
    rs67922231,2
    C,F,A,H--119360867(+) CTCCAT/CTGATC 1 -- int121Minor allele frequency- C:0.12NS EA NA WA 2484
    rs746605701,2
    --119360890(+) GCAAAG/TAAACA 1 -- int10--------
    rs1889736971,2
    --119360942(+) GGTGCC/TACGGC 1 -- ut310--------
    rs84221,2
    C,F,H--119360944(+) TGCCAC/G/TGGCAT 2 -- ut3116MN NA NS EA CSA 1181

    HapMap Linkage Disequilibrium report for POPDC2 (119355304 - 119384171 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for POPDC2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv527724CNV Loss19592680
    nsv520805CNV Loss19592680
    nsv829695CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing POPDC2
    DNA2.0 Custom Variant and Variant Library Synthesis for POPDC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605823    OMIM disorders: --


    Find genes that share disorders with POPDC2           About GenesLikeMe


    Export disorders for POPDC2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for POPDC2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with POPDC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. (PubMed id 10882522)1, 2, 3, 9 Andree B.... Brand T. (Dev. Biol. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)
    6. Popeye domain containing gene 2 (Popdc2) is a myocyte-specific differentiation marker during chick heart development. (PubMed id 14991725)9 Breher S.S....Brand T. (Dev. Dyn. 2004)
    7. Mutants of GABA transaminase (POP2) suppress the severe phenotype of succinic semialdehyde dehydrogenase (ssadh) mutants in Arabidopsis. (PubMed id 18846220)9 Ludewig F....BouchAc N. (PLoS ONE 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64091 HGNC: 17648 AceView: COX17andPOPDC2 Ensembl:ENSG00000121577 euGenes: HUgn64091
    ECgene: POPDC2 H-InvDB: POPDC2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for POPDC2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for POPDC2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for POPDC2 gene:
    Search GeneIP for patents involving POPDC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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