Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POP7 Gene

protein-coding   GIFtS: 50
GCID: GC07P100303

Processing Of Precursor 7, Ribonuclease P/MRP Subunit (S....

(Previous names: processing of precursor 7, ribonuclease P subunit (S. cerevisiae))
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Processing Of Precursor 7, Ribonuclease P/MRP Subunit (S.
Cerevisiae)1 2
     Processing Of Precursor 7, Ribonuclease P Subunit (S. Cerevisiae)1
RPP202 3 5     0610037N12Rik2
Ribonuclease P Protein Subunit P201 2     RPP22
Ribonucleases P/MRP Protein Subunit POP7 Homolog2 3     POP7 (Processing Of Precursor, S. Cerevisiae) Homolog2
hPOP72 3     Processing Of Precursor 7, Ribonuclease P Subunit2
RNaseP Protein P202 3     EC 3.1.26.53

External Ids:    HGNC: 199491   Entrez Gene: 102482   Ensembl: ENSG000001723367   OMIM: 6061135   UniProtKB: O758173   

Export aliases for POP7 gene to outside databases

Previous GC identifers: GC07P099917 GC07P099948 GC07P100141 GC07P094934


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for POP7 Gene: 
POP7 (processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)) is a protein-coding gene. Diseases associated with POP7 include cartilage-hair hypoplasia. GO annotations related to this gene include protein binding and ribonuclease P activity.

UniProtKB/Swiss-Prot: POP7_HUMAN, O75817
Function: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their
5'-ends

Gene Wiki entry for POP7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POP7 gene promoter:
         ER-alpha   AP-1   ATF-2   p300   MyoD   Lmo2   CREB   deltaCREB   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPOP7 promoter sequence
   Search SABiosciences Chromatin IP Primers for POP7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POP7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

POP7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POP7 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P100303:  view genomic region     (about GC identifiers)

Start:
100,303,676 bp from pter      End:
100,305,123 bp from pter
Size:
1,448 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 99,663,281-99,664,728     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: POP7_HUMAN, O75817 (See protein sequence)
Recommended Name: Ribonuclease P protein subunit p20  
Size: 140 amino acids; 15651 Da
Subunit: Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of a RNA moiety and at
least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists
of a RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40,
POP5 and RPP21. Interacts with RPP25. RPP20/POP7 is probably a dimer
Subcellular location: Nucleus, nucleolus (Potential)
Secondary accessions: A4D2E0 Q9BV74

Explore the universe of human proteins at neXtProt for POP7: NX_O75817

Explore proteomics data for POP7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75817

  • POP7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    POP7 Protein Expression
    REFSEQ proteins: NP_005828.2  
    ENSEMBL proteins: 
     ENSP00000304353   ENSP00000387814  

    Human Recombinant Protein Products for POP7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for POP7
    OriGene Protein Over-expression Lysate for POP7
    OriGene MassSpec for POP7 
    OriGene Custom Protein Services for POP7
    GenScript Custom Purified and Recombinant Proteins Services for POP7
    Novus Biologicals POP7 Proteins
    Novus Biologicals POP7 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for POP7 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS9630247
    GO:0005655nucleolar ribonuclease P complex TAS9630247

    POP7 for ontologies           About GeneDecksing



    POP7 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for POP7
    GenScript Custom Superior Antibodies Services for POP7
    Novus Biologicals POP7 Antibodies
    Abcam antibodies for POP7
    Cloud-Clone Corp. Antibodies for POP7 
    Search ThermoFisher Antibodies for POP7
    LSBio Antibodies in human, mouse, rat for POP7 

    Assay Products for POP7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for POP7
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for POP7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for POP7 
    Cloud-Clone Corp. CLIAs for POP7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR014612 RNase_P/MRP_p20

    Graphical View of Domain Structure for InterPro Entry O75817

    ProtoNet protein and cluster: O75817

    1 Blocks protein domain: IPB002775 Alba

    UniProtKB/Swiss-Prot: POP7_HUMAN, O75817
    Similarity: Belongs to the histone-like Alba family


    POP7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: POP7_HUMAN, O75817
    Function: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their
    5'-ends
    Catalytic activity: Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor

         Enzyme Number (IUBMB): EC 3.1.26.51

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0004526ribonuclease P activity IEA--
    GO:0005515protein binding IPI14715275
         
    POP7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for POP7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for POP7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for POP7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for POP7 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POP7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate POP7
    SwitchGear 3'UTR luciferase reporter plasmidPOP7 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for POP7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POP7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for POP7
    Sirion Biotech Customized adenovirus for overexpression of POP7

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for POP7 (see all 7)
    OriGene ORF clones in mouse, rat for POP7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: POP7 (NM_005837)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for POP7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POP7
    Sirion Biotech Customized lentivirus for stable overexpression of POP7 
                         Customized lentivirus expression plasmids for stable overexpression of POP7 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for POP7
    Search LifeMap BioReagents cell lines for POP7
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POP7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for POP7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes
    2RNA transport
    RNA transport

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2         Kegg Pathways  (Kegg details for POP7):
        Ribosome biogenesis in eukaryotes
    RNA transport


    POP7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POP7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/14 Interacting proteins for POP7 (O758171, 3 ENSP000003043534) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPP25Q9BUL91, 3, ENSP000003176914EBI-366574,EBI-366570 I2D: score=4 STRING: ENSP00000317691
    SNRPNP631621, 3EBI-366574,EBI-712493 I2D: score=1 
    SMN2Q166373, ENSP000003701194I2D: score=2 STRING: ENSP00000370119
    HSPB1P047923, ENSP000002485534I2D: score=3 STRING: ENSP00000248553
    SMN1Q166373I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008033tRNA processing IEA--

    POP7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for POP7

    Search CenterWatch for drugs/clinical trials and news about POP7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for POP7 gene: 
    NM_005837.2  

    Unigene Cluster for POP7:

    Processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
    Hs.416994  [show with all ESTs]
    Unigene Representative Sequence: BU944802
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000303151(uc003uwh.4) ENST00000457480
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat POP7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate POP7
    SwitchGear 3'UTR luciferase reporter plasmidPOP7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for POP7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POP7
    Clone
    Products:
         
    OriGene clones in human, mouse for POP7 (see all 7)
    OriGene ORF clones in mouse, rat for POP7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: POP7 (NM_005837)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for POP7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POP7
    Sirion Biotech Customized lentivirus for stable overexpression of POP7 
                         Customized lentivirus expression plasmids for stable overexpression of POP7 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for POP7
    OriGene qSTAR qPCR primer pairs in human, mouse for POP7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POP7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POP7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POP7

    Additional mRNA sequence: 

    BC001430.2 U94316.1 

    5 DOTS entries:

    DT.455756  DT.92431061  DT.92431059  DT.95286851  DT.102824457 

    24/168 AceView cDNA sequences (see all 168):

    BE349428 AI739502 BE252325 BQ188243 AA077420 AI417351 BE294892 AA308439 
    BF797977 BQ435258 AJ572668 AI080645 BE786338 AA743394 AW901739 CK819581 
    BE382563 BX099360 CR601550 CR608046 CR608631 BG114477 AW296527 BQ068209 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    POP7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGAAAAGG
    POP7 Expression
    About this image


    See POP7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for POP7

    SOURCE GeneReport for Unigene cluster: Hs.416994
        SABiosciences Custom PCR Arrays for POP7
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for POP7
    OriGene qSTAR qPCR primer pairs in human, mouse for POP7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POP7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POP7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POP7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POP7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for POP7 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pop71 , 5 processing of precursor 7, ribonuclease P family, (S. more1, 5 87.38(n)1
    95(a)1
      5 (76.51 cM)5
    740971  NM_028753.21  NP_083029.11 
     1375014385 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj61g072 Transcribed sequence with weak similarity to protein more 77.88(n)    BM571356.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rpp206
    Rpp20
    32(a)
    1 ↔ 1
    X(19638464-19639780)
    worm
    (Caenorhabditis elegans)
    Secernentea Y62E10A.26
    Protein Y62E10A.2
    32(a)
    1 ↔ 1
    IV(13370653-13371613)


    ENSEMBL Gene Tree for POP7 (if available)
    TreeFam Gene Tree for POP7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/93 SNPs in POP7 are shown (see all 93)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1834090861,2
    --100301699(+) TAGCCA/GGGCGT 1 -- us2k10--------
    rs1393029361,2
    --100301732(+) AGCTAA/CTCAGG 1 -- us2k10--------
    rs1888615441,2
    --100301756(+) AGAATC/TGCTTT 1 -- us2k10--------
    rs2217711,2
    C,F,A,H--100301825(-) TCGCTT/CCGTTG 1 -- us2k15Minor allele frequency- C:0.30NA WA 10
    rs1451758811,2
    --100301971(+) CATATG/TCTTGA 1 -- us2k10--------
    rs1121178751,2
    F--100302091(+) ATCATG/ATGAGG 1 -- us2k12Minor allele frequency- A:0.10CSA WA 120
    rs2217701,2
    C,F,A,H--100302094(-) CCTCCA/TCACAT 1 -- us2k133Minor allele frequency- T:0.07NS EA NA WA CSA 3137
    rs1412426881,2
    C--100302120(+) ACAATC/TATGTG 1 -- us2k10--------
    rs1146720101,2
    F--100302121(+) CAATTA/GTGTGA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1180319991,2
    F--100302133(+) CATTTC/TGAAAA 1 -- us2k11Minor allele frequency- T:0.04EA 120

    HapMap Linkage Disequilibrium report for POP7 (100303676 - 100305123 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for POP7:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734888CNV Deletion23290073
    nsv888792CNV Loss21882294
    nsv470381CNV Loss18288195
    nsv888791CNV Loss21882294
    nsv888779CNV Loss21882294
    dgv7399n71CNV Loss21882294
    nsv831072CNV Loss17160897
    nsv8184CNV Loss18304495

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing POP7
    DNA2.0 Custom Variant and Variant Library Synthesis for POP7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606113    OMIM disorders: --

    2 diseases for POP7:    About MalaCards
    cartilage-hair hypoplasia    


    POP7 for disorders           About GeneDecksing


    Export disorders for POP7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for POP7 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with POP7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P. (PubMed id 9630247)1, 2, 3, 9 Jarrous N.... Altman S. (1998)
    2. Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. (PubMed id 15096576)1, 2 Welting T.J.... Pruijn G.J. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    5. Rpp20 interacts with SMN and is re-distributed into SMN granules in response to stress. (PubMed id 14715275)1, 9 Hua Y. and Zhou J. (2004)
    6. Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae. (PubMed id 9618478)1, 9 Stolc V....Altman S. (1998)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10248 HGNC: 19949 AceView: POP7 Ensembl:ENSG00000172336 euGenes: HUgn10248
    ECgene: POP7 Kegg: 10248 H-InvDB: POP7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for POP7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for POP7 gene:
    Search GeneIP for patents involving POP7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for POP7  
     OriGene qPCR primer pairs and template standards for POP7   OriGene Protein Over-expression Lysate for POP7  
     OriGene MassSpec something-or-other for POP7   OriGene clones in human, mouse for POP7  
     OriGene qSTAR qPCR primer pairs in human, mouse for POP7   OriGene Purified Protein for POP7  
     OriGene ORF clones in mouse, rat for POP7   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for POP7   OriGene Custom Protein Services for POP7  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POP7
     QIAGEN SeqTarget long-range PCR primers for resequencing POP7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POP7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POP7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POP7
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POP7
     GenScript Custom Purified and Recombinant Proteins Services for POP7 GenScript cDNA clones with any tag delivered in your preferred vector for POP7
     GenScript Custom Assay Services for POP7 GenScript Custom Superior Antibodies Services for POP7
     GenScript Custom overexpressing Cell Line Services for POP7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in POP7 promoter
     Search Chromatin IP Primers for POP7
     RT2 qPCR Primer Assay in human, mouse, rat POP7
     Search GNC Networks for POP7
     SABiosciences Custom PCR Arrays for POP7
     Search Tocris compounds for POP7
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     POP7 antibodies
     POP7 proteins
     POP7 lysates
     Antibodies for POP7
     See all of Abcam's Antibodies, Kits and Proteins for POP7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for POP7
     Antibodies for POP7
     ELISAs for POP7
     CLIAs for POP7
     Search LifeMap BioReagents cell lines for POP7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POP7
     SwitchGear 3'UTR luciferase reporter plasmids for POP7
     SwitchGear Promoter luciferase reporter plasmids for POP7
     Search ThermoFisher Antibodies for POP7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POP7
     inGenious Targeting Laboratory - Custom generated mouse model solutions for POP7
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for POP7
    Customized:
     lentivirus for stable overexpression of POP7
     lentivirus expression plasmids for stable overexpression of POP7
     adenovirus for overexpression of POP7
     LSBio Antibodies in human, mouse, rat for POP7
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      POP7 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4