Aliases for POM121 Gene
External Ids for POM121 Gene
Previous GeneCards Identifiers for POM121 Gene
This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]
GeneCards Summary for POM121 Gene
POM121 (POM121 Transmembrane Nucleoporin) is a Protein Coding gene. Among its related pathways are Transport of Mature Transcript to Cytoplasm and Regulation of Glucokinase by Glucokinase Regulatory Protein. An important paralog of this gene is POM121C.
UniProtKB/Swiss-Prot for POM121 Gene
Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).