POLRMT Gene
protein-coding GIFtS: 62
GCID: GC19M000617
|
|
polymerase (RNA) mitochondrial (DNA directed)
| |
Aliases
for POLRMT gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polymerase (RNA) Mitochondrial (DNA Directed)1 2 | | H-MtRPOL1 | | APOLMT1 2 5 | | EC 2.7.7.63 8 | | MTRNAP1 2 | | DNA-Directed RNA Polymerase, Mitochondrial2 | | MTRPOL1 2 | | MtRPOL3 |
Export aliases for POLRMT gene to outside databasesPrevious GC identifers: GC19M000669 GC19M000557 GC19M000568 GC19M000387 |
Summaries
for POLRMT gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for POLRMT:
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial geneexpression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Althoughthis polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely relatedto RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RPOM_HUMAN, O00411Function: DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the fourribonucleoside triphosphates as substrates
Gene Wiki entry for POLRMT
|
Genomic Views
for POLRMT gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the POLRMT gene promoter:
Lmo2 MyoD POU3F2 AP-2gamma E47 Egr-4 HEN1 AP-2beta AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for POLRMT
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLRMT |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3POLRMT Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M000617: view genomic region
(about GC identifiers)
Start:
|
617,223 bp from pter |
End:
|
633,568 bp from pter |
Size:
|
16,346 bases |
Orientation:
|
minus strand |
|
Proteins
for POLRMT gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RPOM_HUMAN, O00411 (See
protein sequence)Recommended Name: DNA-directed RNA polymerase, mitochondrial precursor Size: 1230 amino acids; 138620 Da
Subunit: Interacts with TFB1M and TFB2M, leading to the stimulation of transcription. Interacts with TEFM
Subcellular location: Mitochondrion
1 PDB 3D structure from  and Proteopedia  for POLRMT:3SPA (3D)
Secondary accessions: O60370Explore the universe of human proteins at neXtProt for POLRMT: NX_O00411
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O00411
3 DME Specific Peptides for POLRMT (O00411)
POLRMT Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005026.3
ENSEMBL proteins: ENSP00000465759 ENSP00000468658 ENSP00000466504 ENSP00000215591 Reactome Protein details: O00411
Human Recombinant Protein Products for POLRMT:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
POLRMT for ontologies About GeneDecksing
POLRMT Antibody Products:
Assay Products for POLRMT: |
Protein
Domains /
Families
for POLRMT gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POLRMT for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O00411ProtoNet protein and cluster: O00411 1 Blocks protein family: IPB002092 DNA-directed RNA polymerase
UniProtKB/Swiss-Prot: RPOM_HUMAN, O00411Similarity: Belongs to the phage and mitochondrial RNA polymerase family |
Function
for POLRMT gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RPOM_HUMAN, O00411Function: DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the fourribonucleoside triphosphates as substratesCatalytic activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) Genatlas biochemistry entry for POLRMT:mitochondrial RNA polymerase
Enzyme Number (IUBMB): EC 2.7.7.61 2
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
POLRMT for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLRMT (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLRMT
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: POLRMT (NM_005035) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLRMT | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLRMT |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLRMT |
|
Pathways & Interactions
for POLRMT gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Transcription from mitochondrial promoters | | | 2 | ATP/ITP metabolism | | | 3 | Transcription | | | 4 | Mitochondrial Gene Expression | | | 5 | RNA Polymerase III Transcription Initiation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for POLRMT
1  GeneGo (Thomson Reuters) Pathway for POLRMT
1  BioSystems Pathway for POLRMT
5 
Reactome Pathways for POLRMT
POLRMT for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POLRMT
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/240 Interacting proteins for POLRMT (O004112, 3 ENSP000002155914) via UniProtKB, MINT, STRING, and/or I2D (see all 240)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006390 | transcription from mitochondrial promoter |
TAS | -- | | GO:0006391 | transcription initiation from mitochondrial promoter |
TAS | -- | | GO:0010467 | gene expression |
TAS | -- |
POLRMT for ontologies About GeneDecksing
|
Drugs & Compounds
for POLRMT gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
POLRMT for compounds About GeneDecksing
 Browse Tocris compounds for POLRMT
7 HMDB Compounds for POLRMT About this table
1 Novoseek chemical compound relationship for POLRMT gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| nucleoside |
51.7 |
1 |
11526116 (1) |
Search CenterWatch for drugs/clinical trials and news about POLRMT / RPOM
|
Transcripts
for POLRMT gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for POLRMT gene: NM_005035.3 Unigene Cluster for POLRMT: Polymerase (RNA) mitochondrial (DNA directed) Hs.254113 [show with all ESTs]Unigene Representative Sequence: U7537012 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000588649 ENST00000592633 ENST00000587057 ENST00000589961 ENST00000590336
ENST00000586384 ENST00000590709 ENST00000590573 ENST00000588630 ENST00000586468
ENST00000592863 ENST00000215591(uc002lpf.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLRMT (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLRMT
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: POLRMT (NM_005035) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLRMT | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLRMT |
Additional cDNA sequence: AB209920.1 AK225723.1 AK225865.1 AK302877.1 AK307525.1 BC024170.2 BC030829.1 BC070057.1 BC098387.1 U75370.1 9 DOTS entries: DT.413532 DT.102831307 DT.87016292 DT.100654690 DT.121434595 DT.102831308 DT.95073035 DT.95105973 DT.100812718 24/188 AceView cDNA sequences (see all 188): BM930237 AW044314 AA318636 AW293103 CD366855 AI743308 BQ187677 BQ063393 BC070057 BM707846 AA721356 BM850744 BM561590 AW291590 BM683717 BU553405 AW873537 BF195560 AW298202 BX362987 BE675494 AA550774 AW295276 AA565330
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for POLRMT (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | |
| ExUns: | 17 | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23a | · | 23b | · | 23c |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for POLRMT
|
Expression
for POLRMT gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| POLRMT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACCAGGTGT
About this image
See POLRMT Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POLRMT
SOURCE GeneReport for Unigene cluster: Hs.254113
SABiosciences Custom PCR Arrays for POLRMT
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLRMT
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POLRMT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLRMT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLRMT | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLRMT |
Orthologs
for POLRMT gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for POLRMT gene from 9/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Polrmt1 , 5 |
polymerase (RNA) mitochondrial (DNA directed)1, 5 |
73.35(n)1
68.59(a)1 |
|
10 (39.72 cM)5
2161511 NM_172551.31 NP_766139.21
797361235 |
chicken
(Gallus gallus) |
Aves |
POLRMT1 |
polymerase (RNA) mitochondrial (DNA directed) |
59.27(n)
50(a) |
|
420084 XM_418204.3 XP_418204.3 |
lizard
(Anolis carolinensis) |
Reptilia |
POLRMT6 |
-- |
66(a) |
1 ↔ 1 |
AAWZ02037496(3378-13078) |
African clawed frog
(Xenopus laevis) |
Amphibia |
polrmt-A-prov2 |
polymerase (RNA) mitochondrial (DNA directed) |
74.91(n) |
|
AF200705.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb73g102 |
wufb73g10 |
75.11(n) |
|
322808 57043062 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG46443
mtRNApol1 |
DNA-directed RNA polymerase III3
mitochondrial RNA polymerase1 |
42(a)3
54.2(n)1
45.63(a)1 |
|
332851 NM_134721.21 NP_608565.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y105E8A.233 |
-- |
37(a) |
|
I(14560229-14573885) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
SCA31 |
DNA-directed RNA polymerase 3 |
48.17(n)
43.4(a) |
|
816946 NM_127973.4 NP_179989.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.41482 |
O.sativa mRNA for putative T3/T7-like RNA polymerase, more |
72.07(n) |
|
AK069977.1 |
ENSEMBL Gene Tree for POLRMT (if available)
TreeFam Gene Tree for POLRMT (if available) |
Paralogs
for POLRMT gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for POLRMT gene
POLRMT for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for POLRMT
PGOHUM00000237133 PGOHUM00000234186
|
Genomic Variants
for POLRMT gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for POLRMT (617223 - 633568 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for POLRMT
5 CNVs: 73266 30052 30050 30051 30053
Human Gene Mutation Database (HGMD): POLRMT
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLRMT |
|
Disorders
/ Diseases
for POLRMT gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POLRMT for disorders About GeneDecksing
OMIM gene information: 601778
OMIM disorders: --
5  diseases for POLRMT: About MalaCardsautosomal dominant progressive external ophthalmoplegia essential thrombocythemia ophthalmoplegia immunodeficiency
malaria
1 Novoseek disease relationship for POLRMT gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| aids |
0.742 |
1 |
11526116 (1) |
Human Genome Epidemiology (HuGE) Navigator: POLRMT (2 documents)
Export disorders for POLRMT gene to outside databases
|
Publications
for POLRMT gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for POLRMT gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with POLRMT) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database. (PubMed id 9097968)1, 2, 3 Tiranti V....Zeviani M. (1997)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. (PubMed id 12068295)1, 2 Falkenberg M....Gustafsson C.M. (2002)
- Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression. (PubMed id 17337445)1, 9 Wang Z....Shadel G.S. (2007)
- DNA conformation-dependent activities of human mitoch ondrial RNA polymerase. (PubMed id 19624753)1, 9 Fukuoh A....Kang D. (2009)
- The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells. (PubMed id 15526033)1, 9 Gaspari M.... Gustafsson C.M. (2004)
- Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin. (PubMed id 16079853)1, 9 Kravchenko J.E....Chumakov P.M. (2005)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Structure of human mitochondrial RNA polymerase. (PubMed id 21947009)1 Ringel R....Temiakov D. (2011)
- Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
|
External Searches for POLRMT gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing POLRMT gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POLRMT gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POLRMT gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for POLRMT | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for POLRMT gene:
Search GeneIP for patents involving POLRMT
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for POLRMT gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for POLRMT | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLRMT | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLRMT | | | OriGene Protein Over-expression Lysate for POLRMT | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for POLRMT | | OriGene 3'-UTR Clone for POLRMT | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLRMT | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLRMT | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for POLRMT | | OriGene Custom Protein Services for POLRMT | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POLRMT | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLRMT | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLRMT | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLRMT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLRMT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLRMT |
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| | | | Search Tocris compounds for POLRMT |
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 | | | POLRMT Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLRMT |
|  |  |  |  | | | | Search ThermoFisher Antibodies for POLRMT |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLRMT |
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