POLR2M Gene
protein-coding GIFtS: 43
GCID: GC15P057888
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polymerase (RNA) II (DNA directed) polypeptide M(Previous names: glutamate receptor, ionotropic, N-methyl D-aspartate-like...)
(Previous symbol: GRINL1A)
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Aliases
for POLR2M gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polymerase (RNA) II (DNA Directed) Polypeptide M1 2 | | DNA-Directed RNA Polymerase II Subunit M, Isoforms 4/52 3 | | GRINL1A1 2 3 5 | | GRINL1A Downstream Protein Gdown42 | | GCOM11 2 | | Protein GRINL1A2 | | Gdown1 2 | | Protein GRINL1A, Isoforms 4/52 | | Gdown11 2 | | DNA-Directed RNA Polymerase II Subunit M3 | | Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A1 2 | | Glutamate Receptor-Like Protein 1A3 |
Export aliases for POLR2M gene to outside databases |
Summaries
for POLR2M gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for POLR2M:
This gene encodes a subunit of RNA polymerase II, a protein complex that is responsible for synthesizing messenger RNAin eukaryotes. The encoded protein functions as a component of a specific form of RNA polymerase II termed Pol II(G).This protein may act as a negative regulator of activator-dependent transcription. Alternate splicing results inmultiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstreamgene MYZAP (myocardial zonula adherens protein). (provided by RefSeq, Nov 2011)
UniProtKB/Swiss-Prot: GRL1A_HUMAN, P0CAP2Function: Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). PolII synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNApolymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation oftranscription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation; thisrepression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a levelequivalent to that of Pol II
Gene Wiki entry for POLR2M (GRINL1A)
|
Genomic Views
for POLR2M gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for POLR2M
Other transcription factors
Search SABiosciences Chromatin IP Primers for POLR2M
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2M |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q21.3 Ensembl cytogenetic band: 15q21.3 HGNC cytogenetic band: 15q21.3POLR2M Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P057888: view genomic region
(about GC identifiers)
Start:
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57,884,231 bp from pter |
End:
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58,074,960 bp from pter |
Size:
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190,730 bases |
Orientation:
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plus strand |
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Proteins
for POLR2M gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GL1AD_HUMAN, Q6EEV4 (See
protein sequence)Recommended Name: DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 Size: 148 amino acids; 15131 Da
Miscellaneous: The adjacent MYZAP and POLR2M genes are part of a complex transcription unit. The respective transcriptsderive from different promoters and are alternatively spliced. In human, some transcripts of the upstream promoter ofMYZAP use exons of the downstream POLR2M gene
Secondary accessions: Q6EEV7Alternative splicing: 6 isoforms: Q6EEV4-1 P0CAP2-1 P0CAP2-2 P0CAP2-3 Q6EEV4-2 P0CAP1-11 (Based on a naturally occurring readthrough transcript which produces a MYZAP-POLR2M fusion protein)UniProtKB/Swiss-Prot: GRL1A_HUMAN, P0CAP2 (See
protein sequence) Recommended Name: DNA-directed RNA polymerase II subunit GRINL1A Size: 368 amino acids; 41740 Da
Subunit: Isoform 1 is a component of the Pol II(G) complex, which contains the RNA polymerase II (Pol II) core complexsubunits and POLR2M isoform 1. Pol II(G) appears to be an abundant form of Pol II
Subcellular location: Isoform 1: Nucleus (Probable)
Miscellaneous: The adjacent MYZAP and POLR2M genes are part of a complex transcription unit. The respective transcriptsderive from different promoters and are alternatively spliced. In human, some transcripts of the upstream promoter ofMYZAP use exons of the downstream POLR2M gene
Secondary accessions: Q6EER8 Q6EES2 Q6EEV3 Q6EF00 Q6EF01 Q6EF02 Q6EF46 Q6EFN8 Q6EM48 Q6K046 Q6K050Q6K051 Q6ZQZ3 Q8NC58 Q8NCF3 Q96DI5 Q96JB7 Q96NF5 Q9Y3V6Alternative splicing: 6 isoforms: P0CAP2-1 P0CAP2-2 P0CAP2-3 Q6EEV4-1 Q6EEV4-2 P0CAP1-11 (Based on a naturally occurring readthrough transcript which produces a MYZAP-POLR2M fusion protein)Explore the universe of human proteins at neXtProt for POLR2M: NX_P0CAP2
Post-translational modifications:
View modification sites using PhosphoSitePlus2 (GRINL1A)View neXtProt modification sites for NX_P0CAP2
POLR2M Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001018112.1 NP_056347.1
ENSEMBL proteins: ENSP00000299638 ENSP00000433988 ENSP00000437015 ENSP00000432615 ENSP00000457886 ENSP00000369930 ENSP00000369937
Human Recombinant Protein Products for POLR2M:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005635 | nuclear envelope |
IDA | -- | | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme |
IDA | -- | | GO:0043025 | neuronal cell body |
IEA | -- |
POLR2M for ontologies About GeneDecksing
POLR2M Antibody Products:
Assay Products for POLR2M: |
Protein
Domains /
Families
for POLR2M gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POLR2M for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6EEV4Graphical View of Domain Structure for InterPro Entry P0CAP2ProtoNet protein and cluster: Q6EEV4 UniProtKB/Swiss-Prot: GRL1A_HUMAN, P0CAP2Similarity: Belongs to the GRINL1 family |
Function
for POLR2M gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: GRL1A_HUMAN, P0CAP2Function: Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). PolII synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNApolymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation oftranscription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation; thisrepression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a levelequivalent to that of Pol II Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003899 | DNA-directed RNA polymerase activity |
IEA | -- |
POLR2M for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2M (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2M (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for POLR2M | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR2M | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2M |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2M |
|
Pathways & Interactions
for POLR2M gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POLR2M
5/23 Interacting proteins for POLR2M (P0CAP23) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0051685 | maintenance of ER location |
IEA | -- |
POLR2M for ontologies About GeneDecksing
|
Drugs & Compounds
for POLR2M gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for POLR2M
Search CenterWatch for drugs/clinical trials and news about POLR2M / GRL1A
|
Transcripts
for POLR2M gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for POLR2M gene (2 alternative transcripts): NM_001018102.1 NM_015532.3 Unigene Cluster for POLR2M: Polymerase (RNA) II (DNA directed) polypeptide M Hs.437256 [show with all ESTs]Unigene Representative Sequence: NM_0010180909 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000299638(uc002aem.3 uc002aep.3 uc010bfx.3 uc002aeq.3 uc002aen.3 uc010bfy.3 uc002aeo.3 uc002aes.3 uc010ugu.2 uc002aet.4 uc002aeu.4)
ENST00000494490(uc002aev.1) ENST00000464277 ENST00000482852 ENST00000567643
ENST00000380557 ENST00000464308 ENST00000562260 ENST00000380563
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2M (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2M (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for POLR2M | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR2M | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2M |
Additional cDNA sequence: AF086209.1 AF326773.1 AK055535.1 AK074767.1 AK074955.1 AK128618.1 AK223571.1 AK308873.1 AL050091.1 AL833028.1 AL833142.1 AY207007.1 AY207459.1 AY208913.1 AY237639.1 AY339380.1 AY341344.1 AY353061.1 AY620236.1 BC001510.2 BC050322.1 BC101645.1 BC112148.1 FJ970029.1 JF419331.1 NR_027390.1 24/25 DOTS entries (see all 25): DT.92439463 DT.97778662 DT.445427 DT.444826 DT.102829994 DT.100020059 DT.99967845 DT.95194234 DT.121054112 DT.95156424 DT.100059260 DT.100805929 DT.100723128 DT.100810013 DT.121054114 DT.121054154 DT.121054217 DT.121222449 DT.121222475 DT.40109899 DT.95156423 DT.95194247 DT.121222489 DT.121222490 24/384 AceView cDNA sequences (see all 384): CD637834 BU633081 BX092469 AY353058 BU164049 BG258119 CA447169 AI873504 AK128618 AY341345 AY237639 CR600323 AA620319 AA780958 BM786632 AL079925 NM_152451 CB131187 AI375286 BM549163 BF725893 BX508828 BU753055 AW274735
GeneLoc Exon Structure
|
Expression
for POLR2M gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| POLR2M expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTTAATAA
About this image
See POLR2M Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POLR2M
SOURCE GeneReport for Unigene cluster: Hs.437256
UniProtKB/Swiss-Prot: GRL1A_HUMAN, P0CAP2Tissue specificity: Detected in adult an fetal brain. Detected in heart, kidney, skeletal muscle, small intestine,lung, prostate and testis
SABiosciences Custom PCR Arrays for POLR2M
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR2M
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat POLR2M | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2M | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2M | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2M |
Orthologs
for POLR2M gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for POLR2M gene from 3/7 species (see all 7) About this table
ENSEMBL Gene Tree for POLR2M (if available)
TreeFam Gene Tree for POLR2M (if available) |
Paralogs
for POLR2M gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for POLR2M gene
2 SIMAP similar genes for POLR2M using alignment to 4 protein entries: GL1AD_HUMAN (see all proteins):GCOM2 GCOM1
POLR2M for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for POLR2M
PGOHUM00000238892
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Genomic Variants
for POLR2M gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for POLR2M (57884231 - 58074960 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for POLR2M: --
Human Gene Mutation Database (HGMD): POLR2M
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for POLR2M gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POLR2M for disorders About GeneDecksing
OMIM gene information: 606485
OMIM disorders: --
2  diseases for POLR2M: About MalaCardsalzheimer's disease prostatitis
Export disorders for POLR2M gene to outside databases
|
Publications
for POLR2M gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for POLR2M gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with POLR2M) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A Mediator-responsive form of metazoan RNA polymerase II. (PubMed id 16769904)1, 2, 3 Hu X.... Gnatt A. (2006)
- Regulation of mammalian transcription by Gdown1 throug h a novel steric crosstalk revealed by cryo-EM. (PubMed id 22850672)1, 3 Wu Y.M....Chang W.H. (2012)
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)1, 2 Zody M.C....Nusbaum C. (2006)
- The human GRINL1A gene defines a complex transcription unit, an unusual form of gene organization in eukaryotes. (PubMed id 15233991)1, 2 Roginski R.S.... Rowen L. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. (PubMed id 15175163)1, 2 Sato S....Conaway R.C. (2004)
- Assignment of an ionotropic glutamate receptor-like gene (GRINL1A) to human chromosome 15q22.1 by in situ hybridization. (PubMed id 11474202)1, 2 Roginski R.S.... Sciorra L.J. (2001)
- Structural basis for the interaction between dynein l ight chain 1 and the glutamate channel homolog GRINL1A. (PubMed id 20412299)1, 9 GarcA-a-Mayoral M.F....Bruix M. (2010)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
|
External Searches for POLR2M gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing POLR2M gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POLR2M gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POLR2M gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for POLR2M | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for POLR2M gene:
Search GeneIP for patents involving POLR2M
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for POLR2M gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for POLR2M | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLR2M | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR2M | | | OriGene Protein Over-expression Lysate for POLR2M | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for POLR2M | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2M | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2M | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for POLR2M | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POLR2M | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR2M | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2M | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLR2M | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2M | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2M |
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| | | | Search Tocris compounds for POLR2M |
| |  |  |  |  | | | | |
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 | | | POLR2M Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2M |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2M |
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