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POLR2J3 Gene

protein-coding   GIFtS: 43
GCID: GC07M102178

Polymerase (RNA) II (DNA Directed) Polypeptide J3

  Search for POLR2J3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Polymerase (RNA) II (DNA Directed) Polypeptide J31 2     POLR2J22
RPB11b22 3     RPB11b12
DNA-Directed RNA Polymerase II Subunit J32 3     DNA-Directed RNA Polymerase II Subunit 112
RNA Polymerase II Subunit B11-B22 3     DNA-Directed RNA Polymerase II Subunit RPB11-B22

External Ids:    HGNC: 338531   Entrez Gene: 5486442   Ensembl: ENSG000001682557   UniProtKB: Q9H1A73   

Export aliases for POLR2J3 gene to outside databases

Previous GC identifers: GC07M043774 GC07U901566 GC07M101993 GC07M101965 GC07M101538


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for POLR2J3 Gene:
This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on
chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA
polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible
for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts
that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide
J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them
candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or
proteins in vivo. (provided by RefSeq, Jul 2008)

GeneCards Summary for POLR2J3 Gene:
POLR2J3 (polymerase (RNA) II (DNA directed) polypeptide J3) is a protein-coding gene. GO annotations related to this gene include DNA-directed RNA polymerase activity and protein dimerization activity. An important paralog of this gene is POLR2J2.

UniProtKB/Swiss-Prot: RPB1C_HUMAN, Q9H1A7
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional
non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is
composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central
large cleft (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the POLR2J3 gene promoter:
         AML1a   POU3F2 (N-Oct-5a)   HNF-4alpha2   POU3F2   HNF-4alpha1   HEN1   RORalpha1   c-Rel   NRF-2   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPOLR2J3 promoter sequence
   Search Chromatin IP Primers for POLR2J3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POLR2J3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

POLR2J3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POLR2J3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M102178:  view genomic region     (about GC identifiers)

Start:
102,178,365 bp from pter      End:
102,213,103 bp from pter
Size:
34,739 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 101,538,667-101,573,469     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RPB1C_HUMAN, Q9H1A7 (See protein sequence)
Recommended Name: DNA-directed RNA polymerase II subunit RPB11-b2  
Size: 115 amino acids; 13092 Da
Subunit: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits
Secondary accessions: A6NKA1

Explore the universe of human proteins at neXtProt for POLR2J3: NX_Q9H1A7

Post-translational modifications: 

  • Ubiquitination2 at Lys46, Lys51, Lys61
  • Modification sites at PhosphoSitePlus
  • REFSEQ proteins: NP_001091084.2  
    ENSEMBL proteins: 
     ENSP00000419082   ENSP00000419145   ENSP00000368645   ENSP00000419146   ENSP00000425877  
     ENSP00000421085   ENSP00000426619   ENSP00000477228   ENSP00000422109   ENSP00000421950  
     ENSP00000368662  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    POLR: RNA polymerase subunits

    2 InterPro protein domains:
     IPR008193 RNA_pol_Rpb11_13-16kDa_CS
     IPR009025 RBP11-like_dimer

    Graphical View of Domain Structure for InterPro Entry Q9H1A7

    ProtoNet protein and cluster: Q9H1A7

    1 Blocks protein domain: IPB008193 DNA-directed RNA polymerase

    UniProtKB/Swiss-Prot: RPB1C_HUMAN, Q9H1A7
    Similarity: Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family


    Find genes that share domains with POLR2J3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPB1C_HUMAN, Q9H1A7
    Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
    triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional
    non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is
    composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central
    large cleft (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003899DNA-directed RNA polymerase activity IEA--
    GO:0046983protein dimerization activity IEA--
         
    Find genes that share ontologies with POLR2J3           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for POLR2J3
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    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate POLR2J3 (see all 15):
    hsa-miR-4317 hsa-miR-1226 hsa-miR-193a-3p hsa-miR-330-5p hsa-miR-10b hsa-miR-1205 hsa-miR-1291 hsa-miR-10a
    SwitchGear 3'UTR luciferase reporter plasmidPOLR2J3 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RPB1C_HUMAN, Q9H1A7: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    plasma membrane2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0016021integral component of membrane ----

    Find genes that share ontologies with POLR2J3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for POLR2J3 About    
    See pathways by source

    SuperPathContained pathways About
    1Purine metabolism (KEGG)
    Purine metabolism0.38
    Pyrimidine metabolism0.38
    2Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Huntington's disease0.45
    3RNA Polymerase III Transcription Initiation
    RNA polymerase0.45
    4Metabolism
    Metabolic pathways0.38
    5Epstein-Barr virus infection
    Epstein-Barr virus infection


    Find genes that share SuperPaths with POLR2J3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    Selected Kegg Pathways  (Kegg details for POLR2J3) (see all 6):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways
    RNA polymerase
    Huntington's disease

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for POLR2J3
    Interactions:

        GeneGlobe Interaction Network for POLR2J3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for POLR2J3 (ENSP000003686454) via UniProtKB, MINT, STRING, and/or I2D (see all 66)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTPS1ENSP000003616994STRING: ENSP00000361699
    CTPS2ENSP000003522224STRING: ENSP00000352222
    ITPAENSP000003694564STRING: ENSP00000369456
    NME1ENSP000000130344STRING: ENSP00000013034
    NME3ENSP000002193024STRING: ENSP00000219302
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--

    Find genes that share ontologies with POLR2J3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for POLR2J3 (RPB1C)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for POLR2J3 gene (2 alternative transcripts): 
    NM_001097615.2  NM_001015884.1  

    Unigene Clusters for POLR2J3:

    Polymerase (RNA) II (DNA directed) polypeptide J3
    Hs.610255  [show with all ESTs], Hs.656696  [show with all ESTs]
    Unigene Representative Sequences: BC071870, BC110985
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000464525 ENST00000489144(uc011kkw.1) ENST00000379340 ENST00000486319(uc003uzw.2)
    ENST00000503564 ENST00000511773 ENST00000508848 ENST00000513506 ENST00000504677
    ENST00000506060 ENST00000502415 ENST00000507355 ENST00000608621 ENST00000511313
    ENST00000504157 ENST00000508910 ENST00000443430 ENST00000513438
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate POLR2J3 (see all 15):
    hsa-miR-4317 hsa-miR-1226 hsa-miR-193a-3p hsa-miR-330-5p hsa-miR-10b hsa-miR-1205 hsa-miR-1291 hsa-miR-10a
    SwitchGear 3'UTR luciferase reporter plasmidPOLR2J3 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: POLR2J3 (NM_001097615)
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat POLR2J3
      QuantiFast Probe-based Assays in human, mouse, rat POLR2J3

    Additional mRNA sequence: 

    AF468111.1 AJ277740.1 AJ277741.1 AK309487.1 BC044209.1 BC110985.1 BC141857.1 

    Selected DOTS entries (see all 77):

    DT.97864589  DT.95266122  DT.100646865  DT.304182  DT.450079  DT.100024896  DT.92461418  DT.102840198 
    DT.92439249  DT.100884189  DT.210211  DT.110014  DT.87017605  DT.95266112  DT.121040464  DT.100884197 
    DT.102840191  DT.92417454  DT.121040135  DT.92382771  DT.92461430  DT.97864592  DT.100762651  DT.40314907 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    POLR2J3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCAGCTCAT
    POLR2J3 Expression
    About this image

    POLR2J3 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene clusters: Hs.610255 Hs.656696
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2J3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for POLR2J3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia --
    Uncharacterized protein
    81(a)
    1 → many
    6(7707466-7710696)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    80(a)
    1 → many
    GL343653.1(72885-73238)
    zebrafish
    (Danio rerio)
    Actinopterygii polr2j6
    polymerase (RNA) II (DNA directed) polypeptide J
    85(a)
    1 → many
    5(64522041-64527647) ENSDARG00000035146
    fruit fly
    (Drosophila melanogaster)
    Insecta Rpb116
    Rpb11
    71(a)
    1 → many
    2L(17409698-17410406)
    worm
    (Caenorhabditis elegans)
    Secernentea rpb-116
    Protein RPB-11 (rpb-11) mRNA, complete cds
    60(a)
    1 → many
    II(14059838-14060622) WBGene00012187
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPB111 RPB11 58.49(n)
    52.83(a)
      854157   NP_014638.1 


    ENSEMBL Gene Tree for POLR2J3 (if available)
    TreeFam Gene Tree for POLR2J3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for POLR2J3 gene
    POLR2J21 2  POLR2J2  ENSG000002702492  
    9 SIMAP similar genes for POLR2J3 using alignment to 6 protein entries:     RPB1C_HUMAN (see all proteins):
    UPK3BL    POLR2J2    POLR2J1    POLR2J    LOC401379    PMS2P5
    C8orf75    POLR1D    UPK3B

    Find genes that share paralogs with POLR2J3           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for POLR2J3
    PGOHUM00000250862 PGOHUM00000250884


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for POLR2J3 (see all 193)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2016177751,2
    C--102178389(+) ATTTCC/TGATAG 1 -- ut310--------
    rs1997139301,2
    C--102178459(+) CTCTCA/GCCAGA 1 -- ut310--------
    rs2014498701,2
    --102178744(+) AAAAA-/TAGTAA 1 -- ut310--------
    rs753595501,2
    C--102180473(-) CACTCA/GCCTGC 1 -- ut310--------
    rs11405741,2
    F--102180493(-) GAAACC/AAAGTG 1 -- ut311Minor allele frequency- A:0.34MN 184
    rs1453466071,2
    C--102180994(+) TGGGC-/CTTCA 
            
    AGATC
    1 -- int10--------
    rs1428535061,2
    C--102181142(+) AAAAAG/TTAGTC 1 -- int10--------
    rs3738584911,2
    C--102181327(+) AAGAA-/GA    
       AAAGG
    AAAAA
    1 -- int10--------
    rs11242571,2
    F,A--102181675(-) CTACTA/CTCTCA 1 -- ut311Minor allele frequency- C:0.04MN 184
    rs2021522241,2
    C,F--102182145(+) AATGGC/G/TGCAAC 1 -- int11EU 475

    HapMap Linkage Disequilibrium report for POLR2J3 (102178365 - 102213103 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for POLR2J3 (see all 33):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv436552CNV Deletion17901297
    esv2734946CNV Deletion23290073
    dgv23n31CNV Duplication19718026
    nsv509219CNV Insertion20534489
    nsv436086CNV Insertion17901297
    nsv5879CNV Loss18451855
    nsv888877CNV Loss21882294
    dgv7412n71CNV Loss21882294
    nsv888836CNV Loss21882294
    nsv888832CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for POLR2J3 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with POLR2J3)
        Utopia: connect your pdf to the dynamic
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    1. [New genes on human chromosome 7: bioinformatic analysis of a gene cluster from the POLR2J family]. (PubMed id 15586814)1, 3 ShpakovskiA- D.G....ShpakovskiA- G.V. (Bioorg. Khim. 2004)
    2. A human RNA polymerase II subunit is encoded by a recently generated multigene family. (PubMed id 11747469)1, 2 Grandemange S.... Vigneron M. (BMC Mol. Biol. 2001)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. Human PMS2 gene family: origin, molecular evolution, and biological implications. (PubMed id 16913423)1 Shpakovskii D.G....Shpakovskii G.V. (Dokl. Biochem. Biophys. 2006)
    8. Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II. (PubMed id 15987790)1 Benga W.J....Vigneron M. (Nucleic Acids Res. 2005)
    9. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (Nature 2003)
    10. The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase II, subunit 11. (PubMed id 12036295)1 Durrin L.K. and Krontiris T.G. (Genomics 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 548644 HGNC: 33853 Ensembl:ENSG00000168255 euGenes: HUgn548644 ECgene: POLR2J3 Kegg: 548644
    H-InvDB: POLR2J3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for POLR2J3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for POLR2J3 gene:
    Search GeneIP for patents involving POLR2J3

    GeneCards and IP:
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