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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POLR2J2 Gene

protein-coding   GIFtS: 47
GCID: GC07M102282

Polymerase (RNA) II (DNA Directed) Polypeptide J2

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Polymerase (RNA) II (DNA Directed) Polypeptide J21 2     HRPB11B2
RPB11b12 3     DNA Directed RNA Polymerase II Polypeptide J-Related2
DNA-Directed RNA Polymerase II Subunit J22 3     DNA-Directed RNA Polymerase II Subunit RPB11-B12
RNA Polymerase II Subunit B11-B12 3     RPB115

External Ids:    HGNC: 232081   Entrez Gene: 2467212   Ensembl: ENSG000002280497   OMIM: 6098815   UniProtKB: Q9GZM33   

Export aliases for POLR2J2 gene to outside databases

Previous GC identifers: GC07U990355 GC07M100764 GC07M101725 GC07M101841 GC07M101875 GC07M101772 GC07M102064 GC07M102278 GC07M043909 GC07M102280 GC07M102179


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for POLR2J2 Gene:
This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on
chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA
polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible
for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts
that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide
J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them
candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or
proteins in vivo. (provided by RefSeq, Jul 2008)

GeneCards Summary for POLR2J2 Gene: 
POLR2J2 (polymerase (RNA) II (DNA directed) polypeptide J2) is a protein-coding gene. Diseases associated with POLR2J2 include huntington's disease, and among its related super-pathways are Purine metabolism and RNA Polymerase III Chain Elongation. GO annotations related to this gene include DNA-directed RNA polymerase activity and DNA binding. An important paralog of this gene is POLR2J3.

UniProtKB/Swiss-Prot: RPB1B_HUMAN, Q9GZM3
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional
non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is
composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central
large cleft (By similarity)

Gene Wiki entry for POLR2J2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POLR2J2 gene promoter:
         c-Fos   AML1a   AP-1   Pax-5   CUTL1   C/EBPalpha   GATA-2   E47   CHOP-10   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPOLR2J2 promoter sequence
   Search SABiosciences Chromatin IP Primers for POLR2J2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2J2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

POLR2J2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POLR2J2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M102282:  view genomic region     (about GC identifiers)

Start:
102,277,195 bp from pter      End:
102,312,176 bp from pter
Size:
34,982 bases      Orientation:
minus strand

2 alternative locations:
Chr7-,CRA_TCAG 101,637,564-101,672,545      Chr7- 102,277,496-102,312,088     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RPB1B_HUMAN, Q9GZM3 (See protein sequence)
Recommended Name: DNA-directed RNA polymerase II subunit RPB11-b1  
Size: 115 amino acids; 13074 Da
Subunit: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q9H1A8
Alternative splicing: 2 isoforms:  Q9GZM3-1   Q9GZM3-2   

Explore the universe of human proteins at neXtProt for POLR2J2: NX_Q9GZM3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9GZM3

  • POLR2J2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins: NP_116581.3  
    ENSEMBL proteins: 
     ENSP00000351218   ENSP00000330898   ENSP00000466522  

    Human Recombinant Protein Products for POLR2J2: 
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    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    POLR2J2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    POLR: RNA polymerase subunits

    2 InterPro protein domains:
     IPR008193 RNA_pol_Rpb11_13-16kDa_CS
     IPR009025 DNA-dir_RNA_pol_RBP11-like

    Graphical View of Domain Structure for InterPro Entry Q9GZM3

    ProtoNet protein and cluster: Q9GZM3

    1 Blocks protein domain: IPB008193 DNA-directed RNA polymerase

    UniProtKB/Swiss-Prot: RPB1B_HUMAN, Q9GZM3
    Similarity: Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family


    POLR2J2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RPB1B_HUMAN, Q9GZM3
    Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
    triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional
    non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is
    composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central
    large cleft (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003899DNA-directed RNA polymerase activity IEA--
    GO:0046983protein dimerization activity IEA--
         
    POLR2J2 for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for POLR2J2 About   (see all 7)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Purine metabolism
    Purine metabolism0.38
    ATP/ITP metabolism0.31
    Pyrimidine metabolism0.38
    2RNA Polymerase III Transcription Initiation
    RNA polymerase0.50
    3Transcription Ligand-Dependent Transcription of Retinoid-Target genes
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes1.00
    4DNA damage Role of Brca1 and Brca2 in DNA repair
    DNA damage Role of Brca1 and Brca2 in DNA repair1.00
    5Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Huntington's disease0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 EMD Millipore Pathways for POLR2J2
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes
    DNA damage Role of Brca1 and Brca2 in DNA repair
    ATP/ITP metabolism


    3 GeneGo (Thomson Reuters) Pathways for POLR2J2
        DNA damage Role of Brca1 and Brca2 in DNA repair
    ATP/ITP metabolism
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes


    5/6         Kegg Pathways  (Kegg details for POLR2J2) (see all 6):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways
    RNA polymerase
    Huntington's disease


    POLR2J2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POLR2J2

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--

    POLR2J2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for POLR2J2:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for POLR2J2 (RPB1B)

    Search CenterWatch for drugs/clinical trials and news about POLR2J2 / RPB1B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for POLR2J2 gene (3 alternative transcripts): 
    NM_032959.5  NM_032958.3  NM_145325.2  

    Unigene Cluster for POLR2J2:

    Polymerase (RNA) II (DNA directed) polypeptide J2
    Hs.732239  [show with all ESTs]
    Unigene Representative Sequence: BC050598
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358438 ENST00000333432 ENST00000591000
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2J2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2J2

    Additional mRNA sequence: 

    AB209398.1 AJ277739.1 BC050598.1 BC056864.1 

    24/33 DOTS entries (see all 33):

    DT.95266122  DT.92004070  DT.100656380  DT.92469765  DT.40282970  DT.92461418  DT.97864589  DT.304182 
    DT.100024896  DT.100646865  DT.100762651  DT.102840198  DT.110014  DT.40116989  DT.40240626  DT.97864592 
    DT.100017021  DT.100884197  DT.100884198  DT.100884209  DT.102840203  DT.121040127  DT.121040259  DT.121040398 

    24/37 AceView cDNA sequences (see all 37):

    BF914307 CR615948 CR600981 AA077060 CR614811 BM843730 BI056959 AA704646 
    AA077481 BQ636668 CR606303 CR621944 AI868123 BQ428503 BM847378 CR624568 
    BX442077 CF144966 BX954396 BG741801 BI333945 AJ277741 F30752 AA077761 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    POLR2J2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    POLR2J2 Expression
    About this image


    Genevestigator expression for POLR2J2

    SOURCE GeneReport for Unigene cluster: Hs.732239

    UniProtKB/Swiss-Prot: RPB1B_HUMAN, Q9GZM3
    Tissue specificity: Ubiquitously expressed

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for POLR2J2 gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves --
    --
    88(a)
    possible ortholog
    19(4167435-4168658)
    lizard
    (Anolis carolinensis)
    Reptilia POLR2J6
    Uncharacterized protein
    79(a)
    possible ortholog
    GL343653.1(72885-73238)
    zebrafish
    (Danio rerio)
    Actinopterygii polr2j6
    polymerase (RNA) II (DNA directed) polypeptide J
    85(a)
    1 → many
    5(64522041-64527647)
    fruit fly
    (Drosophila melanogaster)
    Insecta Rpb116
    Rpb11
    70(a)
    1 → many
    2L(17409698-17410406)
    worm
    (Caenorhabditis elegans)
    Secernentea rpb-116
    Probable DNA-directed RNA polymerase II subunit RP...
    59(a)
    1 → many
    II(14059838-14060622)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RPB111 Rpb11p 58.49(n)
    51.89(a)
      854157   NP_014638.1 
            Species with no ortholog for POLR2J2

    ENSEMBL Gene Tree for POLR2J2 (if available)
    TreeFam Gene Tree for POLR2J2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for POLR2J2 gene
    POLR2J31 2  POLR2J2  ENSG000002702492  
    9 SIMAP similar genes for POLR2J2 using alignment to 5 protein entries:     RPB1B_HUMAN (see all proteins):
    POLR2J1    POLR2J    POLR2J3    LOC389527    PMS2P1    LOC401379
    PMS2P5    C8orf75    POLR1D

    POLR2J2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/139 SNPs in POLR2J2 are shown (see all 139)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2008566921,2
    C--102285482(+) AATTT-/TTTG  
            
    TTTGT
    1 -- int10--------
    rs2003538821,2
    C--102286085(+) GGTGT-/TATGACT 1 -- int10--------
    rs1436808341,2
    C--102287103(+) TCAAGA/TTAGCC 1 -- int10--------
    rs624834801,2
    C--102287203(+) TCACCC/TGAGGT 1 -- int10--------
    rs354613421,2
    C--102287324(+) AGAAA-/AGA   
       G
    /GAG
    GAGAG
    2 -- int1 cds10--------
    rs1409035281,2
    C--102287364(+) AAGAA-/AGAG  
            
    AGAAA
    1 -- int10--------
    rs106502641,2
    C--102287370(+) GAAAG-/AAAAAGAAA/
    GAAA
    /GAAAGAAA
    GAAAG
    2 -- int1 cds10--------
    rs2008437721,2
    --102287526(+) TCCGC-/CTCTCCC 1 -- int10--------
    rs2013149181,2
    C--102287617(+) TTTTTC/TAGTAC 1 -- int10--------
    rs1393033761,2
    C--102288617(+) GTTGAA/GGCATG 1 -- int10--------

    HapMap Linkage Disequilibrium report for POLR2J2 (102277195 - 102312176 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/40 variations for POLR2J2 (see all 40):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv23n31CNV Duplication19718026
    nsv509219CNV Insertion20534489
    nsv5879CNV Loss18451855
    nsv888877CNV Loss21882294
    nsv469620CNV Loss16826518
    dgv7412n71CNV Loss21882294
    dgv7429n71CNV Loss21882294
    dgv7423n71CNV Loss21882294
    dgv7425n71CNV Loss21882294
    nsv499135CNV Loss21111241

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609881    OMIM disorders: --

    2 diseases for POLR2J2:    About MalaCards
    huntington's disease    


    POLR2J2 for disorders           About GeneDecksing


    Export disorders for POLR2J2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for POLR2J2 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with POLR2J2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. [New genes on human chromosome 7: bioinformatic analysis of a gene cluster from the POLR2J family] (PubMed id 15586814)1, 3 Shpakovskii D.G....Shpakovskii G.V. (2004)
    2. The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase II, subunit 11. (PubMed id 12036295)1, 2 Durrin L.K. and Krontiris T.G. (2002)
    3. A human RNA polymerase II subunit is encoded by a recently generated multigene family. (PubMed id 11747469)1, 2 Grandemange S.... Vigneron M. (2001)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. A germline-specific class of small RNAs binds mammali an Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (2006)
    7. Human PMS2 gene family: origin, molecular evolution, and biological implications. (PubMed id 16913423)1 Shpakovskii D.G....Shpakovskii G.V. (2006)
    8. Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II. (PubMed id 15987790)1 Benga W.J....Vigneron M. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 246721 HGNC: 23208 AceView: POLR2J2 Ensembl:ENSG00000228049 euGenes: HUgn246721
    ECgene: POLR2J2 Kegg: 246721 H-InvDB: POLR2J2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for POLR2J2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for POLR2J2 gene:
    Search GeneIP for patents involving POLR2J2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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