Aliases for POLR2H Gene
External Ids for POLR2H Gene
Previous GeneCards Identifiers for POLR2H Gene
The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
GeneCards Summary for POLR2H Gene
POLR2H (RNA Polymerase II Subunit H) is a Protein Coding gene. Diseases associated with POLR2H include Spherocytosis, Hereditary, Type 5. Among its related pathways are HIV Life Cycle and Formation of HIV elongation complex in the absence of HIV Tat. GO annotations related to this gene include RNA polymerase III activity and RNA polymerase II activity.
UniProtKB/Swiss-Prot for POLR2H Gene
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.