POLR2C Gene
protein-coding GIFtS: 63
GCID: GC16P057496
|
|
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa(Previous name: polymerase (RNA) II (DNA directed) polypeptide C (33kD)...)
| |
Aliases
for POLR2C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa1 2 | | RNA Polymerase II Subunit 32 3 | | RPB31 2 | | RNA Polymerase II Subunit B32 3 | | RPB312 3 | | Polymerase (RNA) II (DNA Directed) Polypeptide C (33kD)1 | | RPB332 3 | | DNA-Directed RNA Polymerase II Subunit RPB32 | | DNA-Directed RNA Polymerase II 33 KDa Polypeptide2 3 | | HRPB331 | | DNA-Directed RNA Polymerase II Subunit C2 3 | | HsRPB31 |
Export aliases for POLR2C gene to outside databasesPrevious GC identifers: GC16P047891 GC16P057556 GC16P057230 GC16P057271 GC16P056054 GC16P043364 |
Summaries
for POLR2C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for POLR2C:
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messengerRNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with anotherpolymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has beenidentified on chromosome 21. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RPB3_HUMAN, P19387Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functionalnon-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It iscomposed of mobile elements that move relative to each other. RPB3 is part of the core element with the central largecleft and the clamp element that moves to open and close the cleft (By similarity)
Gene Wiki entry for POLR2C
|
Genomic Views
for POLR2C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the POLR2C gene promoter:
MyoD CUTL1 CREB MEF-2A deltaCREB aMEF-2 Meis-1a Zic3 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for POLR2C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q13-q21 Ensembl cytogenetic band: 16q21 HGNC cytogenetic band: 16q13-q21POLR2C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P057496: view genomic region
(about GC identifiers)
Start:
|
57,496,299 bp from pter |
End:
|
57,505,922 bp from pter |
Size:
|
9,624 bases |
Orientation:
|
plus strand |
|
Proteins
for POLR2C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RPB3_HUMAN, P19387 (See
protein sequence)Recommended Name: DNA-directed RNA polymerase II subunit RPB3 Size: 275 amino acids; 31441 Da
Subunit: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB11/POLR2J and RPB3/POLR2Csubunits interact with each other
Subcellular location: Nucleus
Secondary accessions: O15161Explore the universe of human proteins at neXtProt for POLR2C: NX_P19387
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P19387
POLR2C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116558.1
ENSEMBL proteins: ENSP00000219252 ENSP00000456367 Reactome Protein details: P19387
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
POLR2C for ontologies About GeneDecksing
POLR2C Antibody Products:
Assay Products for POLR2C: |
Protein
Domains /
Families
for POLR2C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POLR2C for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P19387ProtoNet protein and cluster: P19387 1 Blocks protein family: IPB001514 DNA-directed RNA polymerase
UniProtKB/Swiss-Prot: RPB3_HUMAN, P19387Similarity: Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family |
Function
for POLR2C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RPB3_HUMAN, P19387Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functionalnon-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It iscomposed of mobile elements that move relative to each other. RPB3 is part of the core element with the central largecleft and the clamp element that moves to open and close the cleft (By similarity) Genatlas biochemistry entry for POLR2C:polymerase II,RNA (DNA directed) small polypeptide C (33kDa)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2C (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: POLR2C (NM_032940) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR2C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2C |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2C |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
POLR2C for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for POLR2C:
|
Pathways & Interactions
for POLR2C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/25 super-pathways (see all 25) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Formation of RNA Pol II elongation complex | | | 2 | mRNA Splicing - Major Pathway | | | 3 | Assembly of RNA Polymerase-II Initiation Complex | | | 4 | HIV Infection | | | 5 | Nucleotide Excision Repair | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for POLR2C
5/17 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for POLR2C (see all 17)
3  GeneGo (Thomson Reuters) Pathways for POLR2C
1  BioSystems Pathway for POLR2C
5/49 
Reactome Pathways for POLR2C (see all 49)
5 
Kegg Pathways (Kegg details for POLR2C):
POLR2C for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POLR2C
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/391 Interacting proteins for POLR2C (P193872, 3 ENSP000002192524) via UniProtKB, MINT, STRING, and/or I2D (see all 391)About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000398 | mRNA splicing, via spliceosome |
TAS | -- | | GO:0006281 | DNA repair |
TAS | -- | | GO:0006283 | transcription-coupled nucleotide-excision repair |
TAS | -- | | GO:0006289 | nucleotide-excision repair |
TAS | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- |
POLR2C for ontologies About GeneDecksing
|
Drugs & Compounds
for POLR2C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for POLR2C
Search CenterWatch for drugs/clinical trials and news about POLR2C / RPB3
|
Transcripts
for POLR2C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for POLR2C gene (2 alternative transcripts): NM_032940.2 NM_002694.2 Unigene Cluster for POLR2C: Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa Hs.79402 [show with all ESTs]Unigene Representative Sequence: NM_0329408 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000219252(uc002elt.1) ENST00000563115(uc010vhq.2) ENST00000562953
ENST00000562599 ENST00000564651 ENST00000567982 ENST00000564626 ENST00000563589
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2C (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: POLR2C (NM_032940) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR2C | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2C |
Additional cDNA sequence: AF008443.1 AJ224144.1 AK293112.1 AK295582.1 AK300124.1 BC000409.2 BC003159.1 BC028157.1 CR542041.1 J05448.1 18 DOTS entries: DT.100733658 DT.454003 DT.100673226 DT.419003 DT.95168015 DT.95168017 DT.100887494 DT.100765430 DT.100887499 DT.100887510 DT.95078452 DT.120657520 DT.100887511 DT.92457518 DT.95168020 DT.95320158 DT.120657607 DT.75161520 24/376 AceView cDNA sequences (see all 376): BQ639537 CK819530 BM702967 BU839414 CR620330 CD107266 AW236275 BQ777113 CR600374 BF818831 CR615834 BU070573 AI335813 AI356679 BE882336 CA941597 BM557631 CR594917 BE563113 BC003159 BE646255 CR606923 AA323628 BE889808
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for POLR2C (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | - | | | | - | | - | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for POLR2C
|
Expression
for POLR2C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| POLR2C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACAAAGCAG
About this image
See POLR2C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POLR2C
SOURCE GeneReport for Unigene cluster: Hs.79402
SABiosciences Custom PCR Arrays for POLR2C
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR2C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POLR2C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2C |
Orthologs
for POLR2C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for POLR2C gene from 9/41 species (see all 41) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
POLR2C1 |
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa |
84(n)
96.36(a) |
|
415635 XM_414001.2 XP_414001.1 |
lizard
(Anolis carolinensis) |
Reptilia |
---- |
-- |
97(a)79(a) |
1 ↔ many1 ↔ many |
GL343675.1(192484-199473) GL343202.1(2889123-2889766) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.168832 |
Xenopus laevis transcribed sequence with strong similarity more |
79.09(n) |
|
CA972428.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufk48d012 |
wufk48d01 |
78.84(n) |
|
334669 BC046047.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
RpII331 , 3 |
transcription from Pol II promoter
DNA-directed more3
RNA polymerase II 33kD subunit1 |
69(a)3
68.73(n)1
69.34(a)1 |
|
34D63
347961 NM_058071.31 NP_477419.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C36B1.33
rpb-31 |
DNA directed RNA polymerase II3
Protein RPB-31 |
56(a)3
57.74(n)1
57.99(a)1 |
|
I(8736829-8738823)3
1726801 NM_059960.51 NP_492361.21 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
RPB3(YIL021W)4
RPB31 |
RNA polymerase II third largest subunit B44, part of more4
Rpb3p1 |
51.92(n)1
47.31(a)1 |
|
9(312905-313861)4
8547911, 4 NP_012243.31 NP_012243.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NRPB31 |
DNA-directed RNA polymerase II subunit RPB3-A |
49.87(n)
48.02(a) |
|
816035 NM_127103.2 NP_179145.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.55102 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
70.22(n) |
|
AK120034.1 |
ENSEMBL Gene Tree for POLR2C (if available)
TreeFam Gene Tree for POLR2C (if available) |
Paralogs
for POLR2C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for POLR2C gene
POLR2C for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for POLR2C
PGOHUM00000239146
|
Genomic Variants
for POLR2C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for POLR2C (57496299 - 57505922 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for POLR2C
2 Indels: 77356 88147 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR2C |
|
Disorders
/ Diseases
for POLR2C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POLR2C for disorders About GeneDecksing
OMIM gene information: 180663
OMIM disorders: --
6  diseases for POLR2C: About MalaCardsshigellosis huntington's disease conjunctivitis psoriasis
immunodeficiency malaria
Human Genome Epidemiology (HuGE) Navigator: POLR2C (2 documents)
Export disorders for POLR2C gene to outside databases
|
Publications
for POLR2C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for POLR2C gene, integrated from 9 sources (see all 133):
(articles sorted by number of sources associating them with POLR2C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 2 Loftus B.J.... Adams M.D. (1999)
- Cloning and characterization of the human RNA polymerase I subunit hRPA40. (PubMed id 9540830)1, 2 Dammann R. and Pfeifer G.P. (1998)
- Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. (PubMed id 9852112)1, 2 Kershnar E.... Chiang C.-M. (1998)
- Chromosomal localization of human RNA polymerase II subunit genes. (PubMed id 8034326)1, 3 Acker J....Kedinger C. (1994)
- The amino acid sequence of the human RNA polymerase II 33-kDa subunit hRPB 33 is highly conserved among eukaryotes. (PubMed id 2187864)1, 2 Pati U.K. and Weissman S.M. (1990)
- RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product. (PubMed id 16141233)1, 9 Corbi N....Passananti C. (2005)
- The alpha-like RNA polymerase II core subunit 3 (RPB3) is involved in tissue-specific transcription and muscle differentiation via interaction with the myogenic factor myogenin. (PubMed id 12207009)1, 9 Corbi N....Passananti C. (2002)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for POLR2C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing POLR2C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POLR2C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POLR2C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for POLR2C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for POLR2C gene:
Search GeneIP for patents involving POLR2C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for POLR2C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for POLR2C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLR2C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR2C | | | OriGene Protein Over-expression Lysate for POLR2C | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for POLR2C | | OriGene 3'-UTR Clone for POLR2C | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for POLR2C | | OriGene Custom Protein Services for POLR2C | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POLR2C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR2C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLR2C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2C |
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| | | | Search Tocris compounds for POLR2C |
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 | | | POLR2C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2C |
|  |  |  | | | | ThermoFisher Antibodies for POLR2C |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2C |
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