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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

POLR1E Gene

protein-coding   GIFtS: 51
GCID: GC09P037486

polymerase (RNA) I polypeptide E, 53kDa

(Previous name: polymerase (RNA) I associated factor 1 )
(Previous symbol: PRAF1)
  Search for POLR1E
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for POLR1E    

Aliases
for POLR1E gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Polymerase (RNA) I Polypeptide E, 53kDa1 2     RNA Polymerase I-Associated Factor 532 3
PAF531 2 3     FLJ133901
PRAF11 2 3     FLJ139701
Polymerase (RNA) I Associated Factor 11 2     RP11-405L18.32
DNA-Directed RNA Polymerase I Subunit E2 3     DNA-Directed RNA Polymerase I Subunit RPA492
RNA Polymerase I Subunit A492 3     RNA Polymerase I Associated Factor 532
RNA Polymerase I-Associated Factor 12 3     

External Ids:    HGNC: 176311   Entrez Gene: 644252   Ensembl: ENSG000001370547   UniProtKB: Q9GZS13   

Export aliases for POLR1E gene to outside databases

Previous GC identifers: GC09P037477 GC09P037437


Summaries
for POLR1E gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: RPA49_HUMAN, Q9GZS1
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be
involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and
UBTF/UBF (By similarity)

Gene Wiki entry for POLR1E


Genomic Views
for POLR1E gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008413.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the POLR1E gene promoter:
         Oct-B1   oct-B2   oct-B3   MEF-2   CUTL1   MEF-2A   POU2F1   FOXJ2 (long isoform)   FOXJ2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: POLR1E promoter sequence
   Search SABiosciences Chromatin IP Primers for POLR1E

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR1E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p13.2   Ensembl cytogenetic band:  9p13.2   HGNC cytogenetic band: 9p13.1

POLR1E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POLR1E gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P037486:  view genomic region     (about GC identifiers)

Start:
 37,485,932 bp from pter      End:
 37,503,694 bp from pter
Size:
 17,763 bases      Orientation:
 plus strand

Proteins
for POLR1E gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RPA49_HUMAN, Q9GZS1 (See protein sequence)
Recommended Name: DNA-directed RNA polymerase I subunit RPA49  
Size: 481 amino acids; 53962 Da
Subunit: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity).
Interacts with PAF49/CD3EAP. Also binds UBTF/UBF (By similarity)
Subcellular location: Nucleus, nucleolus
Secondary accessions: Q5VZT3 Q8NBA9 Q96L20
Alternative splicing: 2 isoforms:  Q9GZS1-1   Q9GZS1-2   

Explore the universe of human proteins at neXtProt for POLR1E: NX_Q9GZS1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9GZS1

    • POLR1E Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_071935.1  
    ENSEMBL proteins: 
     ENSP00000367029   ENSP00000367023   ENSP00000399887  

    Human Recombinant Protein Products: 
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    Novus Biologicals POLR1E Protein
    Novus Biologicals POLR1E Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for POLR1E

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus ISS--
    GO:0005737cytoplasm IDA--
    GO:0030054cell junction IDA--


    POLR1E for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for POLR1E

    Protein Domains /
    Families
    for POLR1E gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    POLR1E for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009668 RNA_pol-assoc_fac_A49-like

    Graphical View of Domain Structure for InterPro Entry Q9GZS1

    ProtoNet protein and cluster: Q9GZS1

    UniProtKB/Swiss-Prot: RPA49_HUMAN, Q9GZS1
    Similarity: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family


    Function
    for POLR1E gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RPA49_HUMAN, Q9GZS1
    Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
    triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be
    involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and
    UBTF/UBF (By similarity)

    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate POLR1E:
    hsa-miR-544 hsa-miR-149 hsa-miR-548c-3p hsa-miR-664*
    SwitchGear 3'UTR luciferase reporter plasmid: POLR1E 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLR1E (see all 7)
    OriGene shRNA RFP: POLR1E
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for POLR1E

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003899DNA-directed RNA polymerase activity IEA--
    GO:0005515protein binding ----


    POLR1E for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Polr1e):
     mortality/aging 

    POLR1E for phenotypes           About GeneDecksing


    Pathways & Interactions
    for POLR1E gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Purine metabolism
    		Purine metabolism1.00
    		Pyrimidine metabolism0.38
    2TNF-alpha/NF-kB Signaling Pathway
    		TNF-alpha/NF-kB Signaling Pathway1.00
    3Metabolism
    		Metabolic pathways0.38
    4RNA Polymerase III Transcription Initiation
    		RNA polymerase0.35
    5Formation of RNA Pol II elongation complex
    		Eukaryotic Transcription Initiation0.31

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2 BioSystems Pathways for POLR1E 
        Eukaryotic Transcription Initiation
    TNF-alpha/NF-kB Signaling Pathway


    4         Kegg Pathways  (Kegg details for POLR1E):
        Purine metabolism
    Pyrimidine metabolism
    Metabolic pathways
    RNA polymerase


    POLR1E for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POLR1E

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/82 Interacting proteins for POLR1E (Q9GZS12, 3 ENSP000003670294) via UniProtKB, MINT, STRING, and/or I2D (see all 82)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POLR1BQ9H9Y62, 3, ENSP000002633314MINT-7264825 I2D: score=2 STRING: ENSP00000263331
    POLR2EP193882, 3, ENSP000002155874MINT-7264825 I2D: score=1 STRING: ENSP00000215587
    POLR1AO956022, 3, ENSP000002638574MINT-7264825 MINT-7264930 I2D: score=2 STRING: ENSP00000263857
    SUPT16HQ9Y5B92, 3, ENSP000002162974MINT-7264879 MINT-7264825 I2D: score=2 STRING: ENSP00000216297
    POLR1CO151602, 3, ENSP000003614654MINT-7264825 I2D: score=3 STRING: ENSP00000361465
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009303rRNA transcription ISS--


    POLR1E for ontologies           About GeneDecksing



    Drugs & Compounds
    for POLR1E gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for POLR1E:
    Small Molecule - inhibitor
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    Browse Tocris compounds for POLR1E

    6 HMDB Compounds for POLR1E    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Cytidine triphosphatecytidine 5'-(tetrahydrogen triphosphate) (see all 15)65-47-4--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--
    Uridine triphosphate5'-UTP (see all 7)63-39-8--
    Search CenterWatch for drugs/clinical trials and news about POLR1E / RPA49 

    Transcripts
    for POLR1E gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for POLR1E gene: 
    NM_022490.1  

    Unigene Clusters for POLR1E:

    Polymerase (RNA) I polypeptide E, 53kDa
    Hs.591087  [show with all ESTs], Hs.733126  [show with all ESTs]
    Unigene Representative Sequences: AK225050, AK125471
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377798(uc003zzy.1 uc011lqk.1) ENST00000377792(uc003zzz.1)
    ENST00000442009(uc011lqj.1)

    miRNA
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    hsa-miR-544 hsa-miR-149 hsa-miR-548c-3p hsa-miR-664*
    SwitchGear 3'UTR luciferase reporter plasmid: POLR1E 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLR1E (see all 7)
    OriGene shRNA RFP: POLR1E
    OriGene siRNA: POLR1E
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLR1E
    Clone
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    GenScript: all cDNA clones in your preferred vector: POLR1E (NM_022490)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR1E 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR1E
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR1E

    Additional cDNA sequence: 

    AK125471.1 BC009757.2 BC014180.2 

    10 DOTS entries:

    DT.111178  DT.97815129  DT.100669496  DT.101954912  DT.100788284  DT.75153028  DT.100731904  DT.100788281 
    DT.101980862  DT.70105244 

    24/158 AceView cDNA sequences (see all 158):

    BM742639 BM836790 BM773117 AU143190 CR619318 CR615159 BM754510 BM765182 
    BE780147 CB136566 CR612093 BQ430252 CR620462 BQ433912 AK024032 CR592070 
    CR598021 BQ433552 BM754578 CR611501 AI433585 BE613824 CA415731 W03691 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for POLR1E    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b
    SP1:              -                                                                           
    SP2:                                                                                          
    SP3:                                                                                          


    ECgene alternative splicing isoforms for POLR1E

    Expression
    for POLR1E gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    POLR1E expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATCACGCCAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See POLR1E Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for POLR1E

    SOURCE GeneReport for Unigene clusters: Hs.591087 Hs.733126
        SABiosciences Custom PCR Arrays for POLR1E
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR1E

    Orthologs
    for POLR1E gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for POLR1E gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Polr1e1 , 5 polymerase (RNA) I polypeptide E1, 5 81.29(n)1
    77.59(a)1    		   4 (23.67 cM)5
    644241  NM_022811.21  NP_073722.11 
     450185835 
    chicken
    (Gallus gallus)    		 Aves POLR1E1 polymerase (RNA) I polypeptide E, 53kDa 66.91(n)
    61.17(a)    		   426805  XM_424416.3  XP_424416.3 
    lizard
    (Anolis carolinensis)    		 Reptilia POLR1E6
    		 --
    		 54(a)
    		 1 ↔ 1
    		 GL343201.1(3682156-3698717)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.58522 Xenopus laevis transcribed sequence with weak similarity to protein refNP_071935.1 (H.sapiens) hypothetical protein FLJ13390 similar to PAF53 [Homo sapiens] less 74.45(n)    BX853465.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii polr1e1 polymerase (RNA) I polypeptide E 56.22(n)
    43.03(a)    		   553733  NM_001020704.1  NP_001018540.1 


    ENSEMBL Gene Tree for POLR1E (if available)
    TreeFam Gene Tree for POLR1E (if available) 

    Paralogs
    for POLR1E gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for POLR1E gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/466 NCBI SNPs in POLR1E are shown (see all 466)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1448663141,2
    		C,probable-non-pathogenic37501735(+) ATTCTA/GTGAAG 2 M V mis11Minor allele frequency- G:0.00NA 4550
    rs1128862351,2
    		C,--37484067(+) TCATCCTTC    
       TTT    /-    CTTCT     		1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1877268691,2
    		--37484181(+) GCTAAA/GTGCAA 1 -- us2k10--------
    rs795593651,2
    		C,F,--37484253(+) CACGCC/TTGTAA 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs109733581,2
    		C,F,--37484375(+) AAAAAA/TCAAAA 1 -- us2k19Minor allele frequency- T:0.30NA WA CSA EA 370
    rs1450858871,2
    		--37484387(+) AAAACA/TGAGTG 1 -- us2k10--------
    rs778709391,2
    		C,--37484531(+) CAAACT/CAACAA 1 -- us2k12Minor allele frequency- C:0.04WA 120
    rs1422080801,2
    		--37484543(+) AAACGC/TTGGGA 1 -- us2k10--------
    rs117882931,2
    		C,F,H,--37484796(+) agagaC/Aagggt 1 -- us2k13Minor allele frequency- A:0.13NA 124
    rs109733591,2
    		C,F,--37484814(+) TGTTGC/TCCAGC 1 -- us2k14Minor allele frequency- T:0.38WA CSA 124

    HapMap Linkage Disequilibrium report for POLR1E (37485932 - 37503694 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for POLR1E: --

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    Disorders / Diseases
    for POLR1E gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    POLR1E for disorders           About MalaCards

    POLR1E for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: POLR1E (1 document)

    Export disorders for POLR1E gene to outside databases

    Publications
    for POLR1E gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for POLR1E gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with POLR1E)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    5. RNA polymerase I associated factor 53 binds to the nucleolar transcription factor UBF and functions in specific rDNA transcription. (PubMed id 8641287)1, 3 Hanada K....Muramatsu M. (1996)
    6. Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription. (PubMed id 15226435)1, 9 Yamamoto K....Muramatsu M. (2004)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. RNA polymerase I-specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle. (PubMed id 21263028)1 Albert B....Gadal O. (2011)

    External Searches for POLR1E gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    		PubMed
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing POLR1E gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64425 HGNC: 17631 AceView: PAF53 Ensembl:ENSG00000137054 euGenes: HUgn64425
    ECgene: POLR1E Kegg: 64425 H-InvDB: POLR1E

    Other Databases showing POLR1E gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing POLR1E gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for POLR1E Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for POLR1E gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for POLR1E gene:
    Search GeneIP for patents involving POLR1E

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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