POLR1C Gene
protein-coding GIFtS: 62
GCID: GC06P043484
|
|
polymerase (RNA) I polypeptide C, 30kDa
| |
Aliases
for POLR1C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polymerase (RNA) I Polypeptide C, 30kDa1 2 | | DNA-Directed RNA Polymerase I Subunit C2 3 | | RPA391 2 3 5 | | DNA-Directed RNA Polymerases I And III 40 KDa Polypeptide2 3 | | RPA401 2 3 5 | | RNA Polymerases I And III Subunit AC12 3 | | RPA51 2 5 | | TCS32 5 | | RPAC11 2 5 | | DNA-Directed RNA Polymerases I And III Subunit RPAC12 | | AC402 3 | | POLR1E3 | | RPC402 3 | | |
Export aliases for POLR1C gene to outside databasesPrevious GC identifers: GC06P043481 GC06P043531 GC06P043592 GC06P043202 |
Summaries
for POLR1C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for POLR1C:
The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encodedprotein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome(TCS). (provided by RefSeq, Mar 2011)
UniProtKB/Swiss-Prot: RPAC1_HUMAN, O15160Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursorsand small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central largecleft and probably a clamp element that moves to open and close the cleft (By similarity)
Gene Wiki entry for POLR1C
|
Genomic Views
for POLR1C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the POLR1C gene promoter:
GR SRF RP58 GR-beta RREB-1 SRF (504 AA) FOXD1 CUTL1 STAT3 c-Myb
Other transcription factors
Search SABiosciences Chromatin IP Primers for POLR1C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR1C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1POLR1C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P043484: view genomic region
(about GC identifiers)
Start:
|
43,477,440 bp from pter |
End:
|
43,497,323 bp from pter |
Size:
|
19,884 bases |
Orientation:
|
plus strand |
|
Proteins
for POLR1C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RPAC1_HUMAN, O15160 (See
protein sequence)Recommended Name: DNA-directed RNA polymerases I and III subunit RPAC1 Size: 346 amino acids; 39250 Da
Subunit: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13and 17 subunits, respectively (By similarity)
Subcellular location: Nucleus (By similarity)
Secondary accessions: O75395 Q5JTE3Alternative splicing: 2 isoforms: O15160-1 O15160-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for POLR1C: NX_O15160
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15160
POLR1C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_976035.1
ENSEMBL proteins: ENSP00000395401 ENSP00000361465 ENSP00000361419 ENSP00000307212 ENSP00000409536 ENSP00000423773 Reactome Protein details: O15160
Human Recombinant Protein Products for POLR1C:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
POLR1C for ontologies About GeneDecksing
POLR1C Antibody Products:
Assay Products for POLR1C: |
Protein
Domains /
Families
for POLR1C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POLR1C for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15160ProtoNet protein and cluster: O15160 1 Blocks protein family: IPB001514 DNA-directed RNA polymerase
UniProtKB/Swiss-Prot: RPAC1_HUMAN, O15160Similarity: Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family |
Function
for POLR1C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RPAC1_HUMAN, O15160Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursorsand small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central largecleft and probably a clamp element that moves to open and close the cleft (By similarity) Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0003899 | DNA-directed RNA polymerase activity |
IEA | -- | | GO:0046983 | protein dimerization activity |
IEA | -- |
POLR1C for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for POLR1C:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR1C (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR1C (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: POLR1C (NM_203290) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR1C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR1C |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR1C |
|
Pathways & Interactions
for POLR1C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RNA Polymerase III Transcription Initiation | | | 2 | RNA Polymerase I Chain Elongation | | | 3 | ATP/ITP metabolism | | | 4 | Purine metabolism | | | 5 | Transcription | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for POLR1C
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for POLR1C
1  GeneGo (Thomson Reuters) Pathway for POLR1C
1  BioSystems Pathway for POLR1C
5/17 
Reactome Pathways for POLR1C (see all 17)
5 
Kegg Pathways (Kegg details for POLR1C):
POLR1C for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for POLR1C
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/1035 Interacting proteins for POLR1C (O151602, 3 ENSP000003614654) via UniProtKB, MINT, STRING, and/or I2D (see all 1035)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006360 | transcription from RNA polymerase I promoter |
TAS | -- | | GO:0006361 | transcription initiation from RNA polymerase I promoter |
TAS | -- | | GO:0006362 | transcription elongation from RNA polymerase I promoter |
TAS | -- | | GO:0006363 | termination of RNA polymerase I transcription |
TAS | -- | | GO:0006383 | transcription from RNA polymerase III promoter |
TAS | -- |
POLR1C for ontologies About GeneDecksing
|
Drugs & Compounds
for POLR1C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
POLR1C for compounds About GeneDecksing
 Browse Tocris compounds for POLR1C
6 HMDB Compounds for POLR1C About this table
10/18 Novoseek chemical compound relationships for POLR1C gene (see all 18) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| rrna |
78 |
49 |
8609157 (5), 10567578 (3), 7737154 (2), 15073185 (2) (see all 32) |
| alpha-amanitin |
67.1 |
4 |
10081089 (1), 14565978 (1), 7867928 (1), 11971179 (1) |
| s-napc |
64 |
1 |
7662364 (1) |
| actinomycin d |
56.4 |
14 |
15014084 (1), 14565978 (1), 7593322 (1), 10751146 (1) (see all 12) |
| deae-sephadex a-25 |
53.7 |
1 |
10081089 (1) |
| zeatin |
41.7 |
5 |
7789509 (2), 9512365 (1) |
| 5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole |
41.3 |
1 |
8799815 (1) |
| trna |
40.6 |
1 |
16626295 (1) |
| phosphodiester |
38.5 |
1 |
8413268 (1) |
| teniposide |
26.6 |
1 |
2160588 (1) |
Search CenterWatch for drugs/clinical trials and news about POLR1C / RPAC1
|
Transcripts
for POLR1C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for POLR1C gene (2 alternative transcripts): NM_203290.2 NM_004875.2 Unigene Cluster for POLR1C: Polymerase (RNA) I polypeptide C, 30kDa Hs.743509 [show with all ESTs]Unigene Representative Sequence: BU14716410 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000428025 ENST00000372389(uc003ovn.3) ENST00000481352 ENST00000512472
ENST00000372344 ENST00000304004(uc003ovo.2) ENST00000488601 ENST00000423780
ENST00000455605 ENST00000495762
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR1C (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR1C (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: POLR1C (NM_203290) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR1C | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR1C |
Additional cDNA sequence: AF008442.1 AF047441.1 AK293561.1 BC008118.1 BC008863.2 17 DOTS entries: DT.95279834 DT.454089 DT.121405413 DT.121405431 DT.95279835 DT.100821751 DT.100821750 DT.101970772 DT.100693893 DT.121405342 DT.121405575 DT.100821752 DT.100821754 DT.121405747 DT.100821755 DT.121405351 DT.92437924 24/255 AceView cDNA sequences (see all 255): BF792085 BP382028 BM542214 BQ183761 BG765740 BM792971 BM976208 CF130801 CR602912 BQ688311 BG389526 BM701678 BG576888 AI452539 NM_004875 BF312411 BG773833 CR610719 BC008863 CA419783 CR594415 D30849 BM458851 BM982845
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for POLR1C (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for POLR1C
|
Expression
for POLR1C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| POLR1C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAAGTTTTC
About this image
See POLR1C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POLR1C
SOURCE GeneReport for Unigene cluster: Hs.743509
SABiosciences Custom PCR Arrays for POLR1C
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR1C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POLR1C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR1C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR1C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR1C |
Orthologs
for POLR1C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for POLR1C gene from 10/37 species (see all 37) About this table
ENSEMBL Gene Tree for POLR1C (if available)
TreeFam Gene Tree for POLR1C (if available) |
Paralogs
for POLR1C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for POLR1C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for POLR1C (43477440 - 43497323 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for POLR1C
1 CNV: 9530
Human Gene Mutation Database (HGMD): POLR1C
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR1C |
|
Disorders
/ Diseases
for POLR1C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POLR1C for disorders About GeneDecksing
OMIM gene information: 610060
OMIM disorders: 248390
UniProtKB/Swiss-Prot: RPAC1_HUMAN, O15160
Defects in POLR1C are the cause of Treacher Collins syndrome type 3 (TCS3) [MIM:248390]. A form of TreacherCollins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combinationof bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashesmedial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of theexternal auditory canals, and bilateral conductive hearing loss
20/24  diseases for POLR1C (see all 24): About MalaCardstreacher collins syndrome mixed connective tissue disease connective tissue disease treacher collins syndrome 3
mouth disease cockayne syndrome werner syndrome lupus erythematosus
rheumatoid arthritis herpes simplex hepatitis b coloboma
hepatocellular carcinoma hepatitis c retinoblastoma influenza
myeloid leukemia scleroderma arthritis hepatitis
10/15 Novoseek disease relationships for POLR1C gene (see all 15) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sclerosis systemic |
46.8 |
4 |
8390487 (2), 12846047 (1), 7865382 (1) |
| cockayne syndrome |
38.9 |
1 |
18656484 (1) |
| werner syndrome |
34.1 |
1 |
18625297 (1) |
| retinoblastoma |
31.6 |
5 |
9500674 (1), 9066256 (1), 11042686 (1), 9234680 (1) (see all 5) |
| mixed connective tissue disease |
19.9 |
1 |
1698096 (1) |
| influenza |
19 |
10 |
10590147 (2), 20071567 (2), 16227302 (1), 17956624 (1) (see all 6) |
| ascites |
9.6 |
2 |
7929437 (1), 8076598 (1) |
| tumors |
2.15 |
2 |
10913176 (1), 20332106 (1) |
| lupus erythematosus systemic |
0 |
1 |
15621578 (1) |
| virus infection |
0 |
1 |
20011974 (1) |
Export disorders for POLR1C gene to outside databases
|
Publications
for POLR1C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for POLR1C gene, integrated from 9 sources (see all 275):
(articles sorted by number of sources associating them with POLR1C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome. (PubMed id 21131976)1, 2 Dauwerse J.G.... Wieczorek D. (2011)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- A kinetic framework for a mammalian RNA polymerase in vivo. (PubMed id 12446911)1, 3 Dundr M....Misteli T. (2002)
- Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. (PubMed id 12391170)1, 2 Hu P....Hernandez N. (2002)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (2000)
- Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning. (PubMed id 9653160)1, 2 Mao M.... Chen Z. (1998)
- Cloning and characterization of the human RNA polymerase I subunit hRPA40. (PubMed id 9540830)1, 2 Dammann R. and Pfeifer G.P. (1998)
- Rrn3 becomes inactivated in the process of ribosomal DNA transcription. (PubMed id 12646563)1, 9 Hirschler-Laszkiewicz I....Rothblum L.I. (2003)
|
External Searches for POLR1C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing POLR1C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POLR1C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POLR1C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for POLR1C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for POLR1C gene:
Search GeneIP for patents involving POLR1C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for POLR1C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for POLR1C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLR1C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR1C | | | OriGene Protein Over-expression Lysate for POLR1C | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for POLR1C | | OriGene 3'-UTR Clone for POLR1C | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR1C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR1C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for POLR1C | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for POLR1C | | OriGene Custom Protein Services for POLR1C | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POLR1C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR1C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR1C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLR1C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR1C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR1C |
| |
 |  |  |  | |
| | | | Search Tocris compounds for POLR1C |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | POLR1C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR1C |
|  |  |  |  | | | | ThermoFisher Antibody for POLR1C |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR1C |
| |  | |
|
|
|
