POLM Gene
protein-coding GIFtS: 59
GCID: GC07M044111
|
|
polymerase (DNA directed), mu
| |
Aliases
for POLM gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polymerase (DNA Directed), Mu1 2 | | DNA-Directed DNA/RNA Polymerase Mu2 | | Tdt-N1 2 | | Pol Iota2 | | Terminal Transferase2 3 | | Polymerase (DNA-Directed), Mu2 | | Pol Mu2 3 | | EC 2.7.7.73 | | DNA Polymerase Mu2 | | Polmu1 |
Export aliases for POLM gene to outside databasesPrevious GC identifers: GC07M043758 GC07M043818 GC07M043852 GC07M043886 GC07M044078 GC07M043997 |
Summaries
for POLM gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: DPOLM_HUMAN, Q9NP87Function: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination
Gene Wiki entry for POLM (DNA polymerase mu)
|
Genomic Views
for POLM gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the POLM gene promoter:
SRF USF1 Sp1 SRF (504 AA) NF-kappaB AREB6 PPAR-gamma1 FAC1 PPAR-gamma2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for POLM
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLM |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p13 Ensembl cytogenetic band: 7p13 HGNC cytogenetic band: 7p13POLM Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M044111: view genomic region
(about GC identifiers)
Start:
|
44,111,846 bp from pter |
End:
|
44,122,139 bp from pter |
Size:
|
10,294 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 44,151,339-44,161,618 |
|
Proteins
for POLM gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: DPOLM_HUMAN, Q9NP87 (See
protein sequence)Recommended Name: DNA-directed DNA/RNA polymerase mu Size: 494 amino acids; 54816 Da
Cofactor: Magnesium (By similarity)
Subcellular location: Nucleus (By similarity)
Miscellaneous: DPOLM has a reduced ability to distinguish dNTP and rNTP as substrates, and elongates them on DNA primerstrand with a similar efficiency. It is able to polymerize nucleotides on RNA primer strands
2 PDB 3D structures from  and Proteopedia  for POLM:2DUN (3D)
2HTF (3D)
Secondary accessions: D3DVK4Explore the universe of human proteins at neXtProt for POLM: NX_Q9NP87
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NP87
POLM Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_037416.1
ENSEMBL proteins: ENSP00000335141 ENSP00000242248 ENSP00000388230 ENSP00000379174 ENSP00000414025 ENSP00000396571 ENSP00000395043 ENSP00000406750 ENSP00000397135 ENSP00000390899 ENSP00000399244
Human Recombinant Protein Products for POLM:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
POLM for ontologies About GeneDecksing
POLM Antibody Products:
Assay Products for POLM: |
Protein
Domains /
Families
for POLM gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POLM for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q9NP87ProtoNet protein and cluster: Q9NP87 3 Blocks protein families: IPB001357 BRCT domain IPB001726 DNA nucleotidylexotransferase (TDT) signature IPB002054 DNA polymerase family X
UniProtKB/Swiss-Prot: DPOLM_HUMAN, Q9NP87Similarity: Belongs to the DNA polymerase type-X familySimilarity: Contains 1 BRCT domain |
Function
for POLM gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: DPOLM_HUMAN, Q9NP87Function: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombinationCatalytic activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) Genatlas biochemistry entry for POLM:polymerase (DNA-directed), mu
Enzyme Number (IUBMB): EC 2.7.7.71
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0003887 | DNA-directed DNA polymerase activity |
IEA | -- | | GO:0003912 | DNA nucleotidylexotransferase activity |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
POLM for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for POLM:
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Polm):
POLM for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for POLM: Polmtm1Abnd Polmtm1Crey
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLM (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLM
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: POLM (NM_013284) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLM | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLM |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLM |
|
Pathways & Interactions
for POLM gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Non-homologous end-joining | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for POLM
1  GeneGo (Thomson Reuters) Pathway for POLM
1 
Kegg Pathway (Kegg details for POLM):
POLM for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POLM
STRING Interaction
Network Preview (showing 5 interactants - click image to see 17)
5/17 Interacting proteins for POLM (Q9NP873 ENSP000002422484) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
POLM for ontologies About GeneDecksing
|
Drugs & Compounds
for POLM gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for POLM
7 HMDB Compounds for POLM About this table
Search CenterWatch for drugs/clinical trials and news about POLM / DPOLM
|
Transcripts
for POLM gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for POLM gene: NM_013284.2 Unigene Cluster for POLM: Polymerase (DNA directed), mu Hs.596982 [show with all ESTs]Unigene Representative Sequence: BC02630618 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000335195 ENST00000242248(uc003tjt.3 uc003tju.3 uc003tjv.3)
ENST00000435068 ENST00000395831 ENST00000458246(uc003tjx.2 uc011kbt.1)
ENST00000430942 ENST00000467607 ENST00000434229 ENST00000492971 ENST00000492605(uc003tjz.4)
ENST00000418926 ENST00000492312(uc011kbu.1 uc010kxy.2) ENST00000492321
ENST00000497300 ENST00000445616 ENST00000414235 ENST00000452049 ENST00000483644
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLM (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLM
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: POLM (NM_013284) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLM | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLM |
Additional cDNA sequence: AF176097.1 AJ131891.2 AJ844643.1 AK023002.1 AK092801.1 AK092903.1 AK291638.1 AK294449.1 AK307634.1 BC026306.1 BC035685.1 BC049202.1 BC062590.1 17 DOTS entries: DT.100790802 DT.211809 DT.100720427 DT.95373549 DT.65286846 DT.100790797 DT.40238589 DT.95373552 DT.95373557 DT.100790801 DT.91704040 DT.100746940 DT.121122737 DT.97844644 DT.121122740 DT.100698705 DT.121122754 24/159 AceView cDNA sequences (see all 159): AA605050 AI419960 BM756478 BM747399 AA046663 BG231904 BU517199 BX376518 AI057140 AI469103 BE503442 BM808078 AF176097 AA078383 AK092903 AX747737 AX747799 AA917987 CA487434 BC049202 AW137352 AA126044 CR620839 CR606869
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for POLM (see all 18) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | - | | - | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | - | | | | | | | | - | | - | | - | | - | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | - | | - | | - | | - | |
| ExUns: | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | · | 16c | · | 16d | · | 16e | · | 16f | · | 16g |
|---|
|
| SP1: | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | - | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | |
| SP5: | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for POLM
|
Expression
for POLM gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| POLM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGTAAAAAA
About this image
See POLM Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POLM
SOURCE GeneReport for Unigene cluster: Hs.596982
UniProtKB/Swiss-Prot: DPOLM_HUMAN, Q9NP87Tissue specificity: Expressed in a number of tissues. Abundant in thymus
SABiosciences Custom PCR Arrays for POLM
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLM
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POLM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLM | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLM |
Orthologs
for POLM gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for POLM gene from 4/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
--POLM6 |
-- |
56(a)50(a) |
1 ↔ many1 ↔ many |
AAWZ02038928(2885-8894) GL343545.1(467061-472375) |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc561222 |
similar to polymerase (DNA directed), mu |
72.38(n) |
|
393218 BC047832.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G105206 |
DNA polymerase lambda subunit |
21(a) |
1 → many |
1(3465964-3469248) |
rice
(Oryza sativa) |
Liliopsida |
-- |
DNA polymerase lambda, putative, expressed |
21(a) |
1 → many |
6(7127120-7132516) |
ENSEMBL Gene Tree for POLM (if available)
TreeFam Gene Tree for POLM (if available) |
Paralogs
for POLM gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for POLM gene
- POLB2 DNTT2 POLL2
1 SIMAP similar gene for POLM using alignment to 11 protein entries: DPOLM_HUMAN (see all proteins):DNTT
POLM for paralogs About GeneDecksing
|
Genomic Variants
for POLM gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for POLM (44111846 - 44122139 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for POLM
3 CNVs: 4531 4532 31342 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLM |
|
Disorders
/ Diseases
for POLM gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POLM for disorders About GeneDecksing
OMIM gene information: 606344
OMIM disorders: --
7  diseases for POLM: About MalaCardsb-cell non-hodgkin lymphoma non-hodgkin lymphoma xeroderma pigmentosum hodgkin's lymphoma
burkitt's lymphoma lung adenoma adenoma
2 diseases from the University of Copenhagen DISEASES database for POLM:Xeroderma pigmentosum Lung adenoma 1 Novoseek disease relationship for POLM gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| burkitt lymphoma |
39.4 |
1 |
15520469 (1) |
Human Genome Epidemiology (HuGE) Navigator: POLM (1 document)
Export disorders for POLM gene to outside databases
|
Publications
for POLM gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for POLM gene, integrated from 9 sources (see all 46):
(articles sorted by number of sources associating them with POLM) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two novel human and mouse DNA polymerases of the polX family. (PubMed id 10982892)1, 2, 3 Aoufouchi S.... Reynaud C.-A. (2000)
- Polymerase mu is a DNA-directed DNA/RNA polymerase. (PubMed id 12640116)1, 2, 9 Nick McElhinny S.A. and Ramsden D.A. (2003)
- DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. (PubMed id 10747040)1, 2, 9 Dominguez O.... Blanco L. (2000)
- Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ. (PubMed id 19805281)1, 9 Andrade P....Blanco L. (2009)
- Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. (PubMed id 17483519)2, 9 Capp J.P....Canitrot Y. (2007)
- A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. (PubMed id 16963491)1, 9 Juarez R....Blanco L. (2006)
- Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. (PubMed id 15520469)1, 9 Ruiz J.F....Blanco L. (2004)
- Lesion bypass by human DNA polymerase mu reveals a template-dependent, sequence-independent nucleotidyl transferase activity. (PubMed id 14581466)1, 9 Covo S....Livneh Z. (2004)
- Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. (PubMed id 15504045)1, 9 Roettger M.P....Suo Z. (2004)
- Human DNA polymerase mu (Pol mu) exhibits an unusual replication slippage ability at AAF lesion. (PubMed id 11972346)1, 9 Duvauchelle J.B....Cordonnier A.M. (2002)
|
External Searches for POLM gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing POLM gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POLM gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POLM gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for POLM | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/polm/ |
|
| | |
About This Section
| Patent Information for POLM gene:
Search GeneIP for patents involving POLM
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for POLM gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for POLM | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLM | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLM | | | OriGene Protein Over-expression Lysate for POLM | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for POLM | | OriGene 3'-UTR Clone for POLM | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLM | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLM | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for POLM | | OriGene Custom Protein Services for POLM | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POLM | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLM | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLM | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLM |
| |
 |  |  |  | |
| | | | Search Tocris compounds for POLM |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLM |
|  |  |  |  | | | | Search ThermoFisher Antibodies for POLM |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLM |
| |  | |
|
|
|
