Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



POGK Gene

protein-coding   GIFtS: 50
GCID: GC01P166809

Pogo Transposable Element With KRAB Domain

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Pogo Transposable Element With KRAB Domain1 2
KRAB Box Domain Containing 21 2
BASS22
KRBOX22
KIAA15133

External Ids:    HGNC: 188001   Entrez Gene: 576452   Ensembl: ENSG000001431577   UniProtKB: Q9P2153   

Export aliases for POGK gene to outside databases

Previous GC identifers: GC01P164443 GC01P162459 GC01P163504 GC01P163996 GC01P163540 GC01P165075 GC01P138055


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for POGK Gene:
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB
domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the
C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human. (provided by
RefSeq, Jul 2008)

GeneCards Summary for POGK Gene:
POGK (pogo transposable element with KRAB domain) is a protein-coding gene.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the POGK gene promoter:
         NF-1   SREBP-1c   SREBP-1b   Evi-1   c-Rel   SREBP-1a   FOXO4   Msx-1   Ik-1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): POGK promoter sequence
   Search Chromatin IP Primers for POGK

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POGK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24.1   Ensembl cytogenetic band:  1q24.1   HGNC cytogenetic band: 1q23.2

POGK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
POGK gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P166809:  view genomic region     (about GC identifiers)

Start:
166,808,681 bp from pter      End:
166,825,581 bp from pter
Size:
16,901 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: POGK_HUMAN, Q9P215 (See protein sequence)
Recommended Name: Pogo transposable element with KRAB domain  
Size: 609 amino acids; 69444 Da
Sequence caution: Sequence=AAM12422.1; Type=Erroneous initiation; Sequence=BAA96037.1; Type=Erroneous initiation;
Secondary accessions: Q5TIJ1 Q8TE07

Explore the universe of human proteins at neXtProt for POGK: NX_Q9P215

Explore proteomics data for POGK at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See POGK Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060012.3  
    ENSEMBL proteins: 
     ENSP00000404402   ENSP00000356850   ENSP00000356849   ENSP00000442763   ENSP00000441187  

    POGK Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for POGK
    OriGene Protein Over-expression Lysate for POGK
    OriGene MassSpec for POGK
    OriGene Custom Protein Services for POGK
    GenScript Custom Purified and Recombinant Proteins Services for POGK
    Novus Biologicals POGK Proteins
    Novus Biologicals POGK Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for POGK

     
    Search eBioscience for Proteins for POGK 

     
    antibodies-online proteins for POGK (4 products) 

     
    antibodies-online peptides for POGK

    POGK Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for POGK
    OriGene Custom Antibody Services for POGK
    Novus Biologicals POGK Antibodies
    Abcam antibodies for POGK
    Cloud-Clone Corp. Antibodies for POGK
    Search ThermoFisher Antibodies for POGK
    antibodies-online antibodies for POGK (39 products) 

    POGK Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for POGK
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for POGK
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for POGK
    Cloud-Clone Corp. CLIAs for POGK
    Search eBioscience for ELISAs for POGK 
    antibodies-online kits for POGK (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    5 InterPro protein domains:
     IPR006600 HTH_CenpB_DNA-bd_dom
     IPR001909 Krueppel-associated_box
     IPR004875 DDE_SF_endonuclease_CENPB-like
     IPR018586 Brinker_DNA-bd
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9P215

    ProtoNet protein and cluster: Q9P215

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB004875 CENP-B protein


    UniProtKB/Swiss-Prot: POGK_HUMAN, Q9P215
    Similarity: Contains 1 DDE domain
    Similarity: Contains 1 HTH CENPB-type DNA-binding domain
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with POGK           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with POGK           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for POGK:
     Increased G2M DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for POGK

    miRNA
    Products:
        
    miRTarBase miRNAs that target POGK:
    hsa-mir-296-3p (MIRT038358), hsa-mir-18a-5p (MIRT031326), hsa-mir-93-5p (MIRT028075), hsa-mir-130b-3p (MIRT020150), hsa-mir-935 (MIRT036685), hsa-mir-1 (MIRT002759), hsa-mir-99a-5p (MIRT048658), hsa-mir-218-5p (MIRT024246), hsa-mir-17-5p (MIRT050844)

    Block miRNA regulation of human, mouse, rat POGK using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate POGK (see all 34):
    hsa-miR-194* hsa-miR-4307 hsa-miR-1224-3p hsa-miR-3908 hsa-miR-4293 hsa-miR-4324 hsa-miR-1283 hsa-miR-561
    SwitchGear 3'UTR luciferase reporter plasmidPOGK 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for POGK
    Predesigned siRNA for gene silencing in human, mouse, rat POGK

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for POGK

    Clone
    Products:
         
    OriGene clones in human, mouse for POGK (see all 7)
    OriGene ORF clones in mouse, rat for POGK
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: POGK (NM_017542)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for POGK
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POGK
    Addgene plasmids for POGK 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for POGK
    Browse ESI BIO Cell Lines and PureStem Progenitors for POGK 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POGK


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    POGK_HUMAN, Q9P215: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    chloroplast2
    cytosol2
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with POGK           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Array including POGK: 
              Apoptosis 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for POGK

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for POGK (Q9P2151, 2, 3 ENSP000003568494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UCHL3P153742, 3, ENSP000003668194MINT-8276695 I2D: score=2 STRING: ENSP00000366819
    HSP90AB1P082381EBI-2555775,EBI-352572
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007275multicellular organismal development IEA--

    Find genes that share ontologies with POGK           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for POGK



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for POGK gene: 
    NM_017542.3  

    Unigene Cluster for POGK:

    Pogo transposable element with KRAB domain
    Hs.432752  [show with all ESTs]
    Unigene Representative Sequence: NM_017542
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000449930 ENST00000367876(uc001gdt.1 uc010plf.1) ENST00000367875
    ENST00000537173 ENST00000536514(uc010ple.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat POGK using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate POGK (see all 34):
    hsa-miR-194* hsa-miR-4307 hsa-miR-1224-3p hsa-miR-3908 hsa-miR-4293 hsa-miR-4324 hsa-miR-1283 hsa-miR-561
    SwitchGear 3'UTR luciferase reporter plasmidPOGK 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for POGK
    Predesigned siRNA for gene silencing in human, mouse, rat POGK
    Clone
    Products:
         
    OriGene clones in human, mouse for POGK (see all 7)
    OriGene ORF clones in mouse, rat for POGK
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: POGK (NM_017542)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for POGK
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POGK
    Addgene plasmids for POGK 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for POGK
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat POGK
      QuantiTect SYBR Green Assays in human, mouse, rat POGK
      QuantiFast Probe-based Assays in human, mouse, rat POGK

    Additional mRNA sequence: 

    AF111706.1 AF131746.1 AF139898.1 AK027079.1 AK056711.1 AK093951.1 AK293946.1 AK299537.1 
    BC016390.1 BC131624.1 

    9 DOTS entries:

    DT.414808  DT.100816067  DT.97794696  DT.100816069  DT.100837067  DT.121371485  DT.75196718  DT.91755304 
    DT.40248165 

    Selected AceView cDNA sequences (see all 148):

    AF131746 CA427156 AA642458 AA307326 BQ267919 AA758011 AA150509 CB126014 
    BC016390 AW007656 AI613457 AB040946 BE677803 Z44870 BQ425948 AA243079 
    AA826573 BU509712 AI254739 BI492232 H90643 F02061 BM470839 AI561066 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for POGK (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8
    SP1:                          -                       -                                             
    SP2:                                                  -                                             
    SP3:                          -                 -     -     -     -     -     -     -               
    SP4:                          -                                                                     
    SP5:                          -           -     -     -     -                                       


    ECgene alternative splicing isoforms for POGK

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    POGK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTTATTTCT
    POGK Expression
    About this image


    POGK expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Natural Killer Cells Peripheral Blood
    POGK Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    POGK Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.432752
        Pathway & Disease-focused RT2 Profiler PCR Array including POGK: 
              Apoptosis 384HT in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for POGK
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat POGK
    QuantiTect SYBR Green Assays in human, mouse, rat POGK
    QuantiFast Probe-based Assays in human, mouse, rat POGK
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POGK

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for POGK gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pogk1 , 5 pogo transposable element with KRAB domain1, 5 87.48(n)1
    91.27(a)1
      1 (73.75 cM)5
    715921  NM_001142948.11  NP_001136420.11 
     1663846225 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 8)
    Uncharacterized protein
    (see all 8)
    41(a)
    37(a)
    (see all 8)
    many → 1
    many → 1
    (see all 8)
    GL343575.1(139206-143374)
    2(163074032-163075210)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004953281 pogo transposable element with KRAB domain-like 47.38(n)
    37.06(a)
      100495328  XM_002939052.2  XP_002939098.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018870571 pogo transposable element with KRAB domain-like 46.74(n)
    33.78(a)
      101887057  XM_005162791.1  XP_005162848.1 
    worm
    (Caenorhabditis elegans)
    Secernentea W02H5.41 W02H5.4 43.21(n)
    28.04(a)
      189136  NM_071319.1  NP_503720.1 


    ENSEMBL Gene Tree for POGK (if available)
    TreeFam Gene Tree for POGK (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for POGK gene
    10 SIMAP similar genes for POGK using alignment to 4 protein entries:     POGK_HUMAN (see all proteins):
    ZNF28    ZNF761    ZNF300P1    ZNF169    ZNF718    ZNF544
    ZNF684    ZNF250    ZNF254    ZNF248

    Find genes that share paralogs with POGK           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for POGK
    PGOHUM00000235244


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for POGK (see all 304)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1917665841,2
    --166806767(+) GCCTAA/GGCCAG 1 -- us2k10--------
    rs1425845951,2
    C--166807002(+) GTGTC-/TGTG  
     
    /TGTGTG
    TGTGT
    2 -- us2k1 cds10--------
    rs556918381,2
    C--166807005(+) TGTGT-/GTGT  
            
    CTATC
    1 -- us2k10--------
    rs2001607781,2
    --166807044(+) GTATT-/AATTTC 1 -- us2k10--------
    rs105882031,2
    C--166807045(+) TATTAATTTC/
            
    TTTTC
    1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs787972321,2
    --166807045(+) TATTAT/ATTTCT 1 -- us2k11Minor allele frequency- A:0.00CSA 1
    rs1417583451,2
    C--166807045(+) TATTA-/ATTTC 
            
    TTTTC
    1 -- us2k10--------
    rs2011024271,2
    C--166807049(-) GAAAAG/TANNNN 1 -- us2k10--------
    rs1839809841,2
    --166807067(+) CTGGGA/GTGCCA 1 -- us2k10--------
    rs75449401,2
    C,F,A,H--166807182(+) ACTAAG/CATGTC 1 -- us2k123Minor allele frequency- C:0.19NS EA NA WA CSA 2350

    HapMap Linkage Disequilibrium report for POGK (166808681 - 166825581 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for POGK: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing POGK
    DNA2.0 Custom Variant and Variant Library Synthesis for POGK

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with POGK           About GenesLikeMe

    Genetic Association Database (GAD): POGK
    Human Genome Epidemiology (HuGE) Navigator: POGK (2 documents)

    Export disorders for POGK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for POGK gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with POGK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)1, 4 Ehret G.B....Chakravarti A. (Eur. J. Hum. Genet. 2009)
    2. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PubMed id 19064610)1, 4 Cheung C.L....Kung A.W. (Hum. Mol. Genet. 2009)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    5. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    6. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 57645 HGNC: 18800 AceView: POGK Ensembl:ENSG00000143157 euGenes: HUgn57645
    ECgene: POGK H-InvDB: POGK

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1513

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for POGK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for POGK gene:
    Search GeneIP for patents involving POGK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for POGK   OriGene RNAi products in human, mouse, rat for POGK  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for POGK  
     OriGene MassSpec for POGK   OriGene clones in human, mouse for POGK  
     OriGene qSTAR qPCR primer pairs in human, mouse for POGK   OriGene Purified Protein for POGK  
     OriGene ORF clones in mouse, rat for POGK   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for POGK   OriGene Custom Protein Services for POGK  

     
     
     Block miRNA regulation of human, mouse, rat POGK using miScript Target Protectors SeqTarget long-range PCR primers for resequencing POGK
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat POGK Predesigned siRNA for gene silencing in human, mouse, rat POGK
     QuantiFast Probe-based Assays in human, mouse, rat POGK QuantiTect SYBR Green Assays in human, mouse, rat POGK
     PCR Arrays including human, mouse, rat POGK Search Chromatin IP Primers for POGK
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat POGK  Search GeneGlobe Interaction Network for POGK
     Regulatory tfbs in POGK promoter
     GenScript Custom Purified and Recombinant Proteins Services for POGK GenScript cDNA clones with any tag delivered in your preferred vector for POGK
     GenScript Custom Assay Services for POGK GenScript Custom overexpressing Cell Line Services for POGK
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for POGK
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     POGK antibodies
     POGK proteins
     POGK lysates
     Antibodies for POGK
     See all of Abcam's Antibodies, Kits and Proteins for POGK
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for POGK
     Antibodies for POGK
     ELISAs for POGK
     CLIAs for POGK



     Browse ESI BIO Cell Lines and PureStem Progenitors for POGK
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POGK
     SwitchGear 3'UTR luciferase reporter plasmids for POGK
     SwitchGear Promoter luciferase reporter plasmids for POGK
     Search ThermoFisher Antibodies for POGK
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POGK
     Browse compounds at ApexBio
     Addgene plasmids for POGK
      Search eBioscience for proteins for POGK
      Search eBioscience for elisas for POGK
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for POGK
     antibodies-online antibodies for POGK (39 products)
     antibodies-online kits for POGK (4 products)
     antibodies-online peptides for POGK
     antibodies-online proteins for POGK (4 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      POGK gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4