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Aliases for POGK Gene

Aliases for POGK Gene

  • Pogo Transposable Element With KRAB Domain 2 3
  • KRAB Box Domain Containing 2 2 3
  • KIAA1513 4
  • KRBOX2 3
  • LST003 3
  • BASS2 3

External Ids for POGK Gene

Summaries for POGK Gene

Entrez Gene Summary for POGK Gene

  • The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human. [provided by RefSeq, Jul 2008]

GeneCards Summary for POGK Gene

POGK (Pogo Transposable Element With KRAB Domain) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POGK Gene

Genomics for POGK Gene

Genomic Location for POGK Gene

Start:
166,839,444 bp from pter
End:
166,856,344 bp from pter
Size:
16,901 bases
Orientation:
Plus strand

Genomic View for POGK Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for POGK Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POGK Gene

Regulatory Elements for POGK Gene

Proteins for POGK Gene

  • Protein details for POGK Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P215-POGK_HUMAN
    Recommended name:
    Pogo transposable element with KRAB domain
    Protein Accession:
    Q9P215
    Secondary Accessions:
    • Q5TIJ1
    • Q8TE07

    Protein attributes for POGK Gene

    Size:
    609 amino acids
    Molecular mass:
    69444 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAM12422.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA96037.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for POGK Gene

Proteomics data for POGK Gene at MOPED

Post-translational modifications for POGK Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for POGK Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for POGK Gene

Domains for POGK Gene

UniProtKB/Swiss-Prot:

POGK_HUMAN
Domain:
  • Contains 1 DDE domain.:
    • Q9P215
  • Contains 1 HTH CENPB-type DNA-binding domain.:
    • Q9P215
  • Contains 1 KRAB domain.:
    • Q9P215
genes like me logo Genes that share domains with POGK: view

No data available for Gene Families for POGK Gene

Function for POGK Gene

Gene Ontology (GO) - Molecular Function for POGK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 22939624
genes like me logo Genes that share ontologies with POGK: view

Phenotypes for POGK Gene

GenomeRNAi human phenotypes for POGK:
genes like me logo Genes that share phenotypes with POGK: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for POGK Gene

Localization for POGK Gene

Subcellular locations from UniProtKB/Swiss-Prot for POGK Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for POGK Gene COMPARTMENTS Subcellular localization image for POGK gene
Compartment Confidence
nucleus 4
chloroplast 2
cytosol 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for POGK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with POGK: view

Pathways for POGK Gene

SuperPathways for POGK Gene

No Data Available

Gene Ontology (GO) - Biological Process for POGK Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0007275 multicellular organismal development IEA --
genes like me logo Genes that share ontologies with POGK: view

No data available for Pathways by source for POGK Gene

Transcripts for POGK Gene

Unigene Clusters for POGK Gene

Pogo transposable element with KRAB domain:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for POGK Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8
SP1: - -
SP2: -
SP3: - - - - - - - -
SP4: -
SP5: - - - - -
SP6: - - - -

Relevant External Links for POGK Gene

GeneLoc Exon Structure for
POGK
ECgene alternative splicing isoforms for
POGK

Expression for POGK Gene

mRNA expression in normal human tissues for POGK Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for POGK Gene

SOURCE GeneReport for Unigene cluster for POGK Gene Hs.432752

genes like me logo Genes that share expressions with POGK: view

Orthologs for POGK Gene

This gene was present in the common ancestor of animals.

Orthologs for POGK Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia POGK 36
  • 99.62 (n)
  • 99.84 (a)
POGK 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia POGK 36
  • 88.23 (n)
  • 95.57 (a)
POGK 37
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia POGK 36
  • 88.07 (n)
  • 95.4 (a)
POGK 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Pogk 36
  • 87.48 (n)
  • 91.27 (a)
Pogk 16
Pogk 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia POGK 37
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Pogk 36
  • 87.82 (n)
  • 92.89 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 37 (a)
OneToMany
-- 37
  • 33 (a)
OneToMany
-- 37
  • 37 (a)
OneToMany
-- 37
  • 31 (a)
OneToMany
-- 37
  • 34 (a)
OneToMany
-- 37
  • 31 (a)
OneToMany
-- 37
  • 21 (a)
OneToMany
-- 37
  • 41 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495328 36
  • 47.38 (n)
  • 37.06 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC101887057 36
  • 46.74 (n)
  • 33.78 (a)
POGK (1 of 3) 37
  • 31 (a)
OneToMany
POGK (2 of 3) 37
  • 31 (a)
OneToMany
POGK (3 of 3) 37
  • 31 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea W02H5.4 36
  • 43.21 (n)
  • 28.04 (a)
W02H5.4 37
  • 18 (a)
OneToOne
Species with no ortholog for POGK:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for POGK Gene

ENSEMBL:
Gene Tree for POGK (if available)
TreeFam:
Gene Tree for POGK (if available)

Paralogs for POGK Gene

Selected SIMAP similar genes for POGK Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for POGK Gene

genes like me logo Genes that share paralogs with POGK: view

No data available for Paralogs for POGK Gene

Variants for POGK Gene

Sequence variations from dbSNP and Humsavar for POGK Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs742006 -- 166,854,939(-) GGTCA(C/G)ACTTG downstream-variant-500B
rs760536 -- 166,845,119(+) CAGGC(A/G)GTGGT intron-variant
rs765739 -- 166,837,568(-) CTGTA(A/C)TTGCT upstream-variant-2KB
rs879654 -- 166,839,745(-) GGCGC(A/C)GCCCG intron-variant, utr-variant-5-prime
rs1476347 -- 166,846,350(+) AGTTA(G/T)TTTTC intron-variant

Relevant External Links for POGK Gene

HapMap Linkage Disequilibrium report
POGK

No data available for Structural Variations from Database of Genomic Variants (DGV) for POGK Gene

Disorders for POGK Gene

Relevant External Links for POGK

Genetic Association Database (GAD)
POGK
Human Genome Epidemiology (HuGE) Navigator
POGK
genes like me logo Genes that share disorders with POGK: view

No data available for UniProtKB/Swiss-Prot for POGK Gene

Publications for POGK Gene

  1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T. … Ohara O. (DNA Res. 2000) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PMID: 19064610) Cheung C.L. … Kung A.W. (Hum. Mol. Genet. 2009) 3 49
  4. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PMID: 19536175) Ehret G.B. … Chakravarti A. (Eur. J. Hum. Genet. 2009) 3 49
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3

Products for POGK Gene

Sources for POGK Gene

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