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Aliases for PODNL1 Gene

Aliases for PODNL1 Gene

  • Podocan-Like 1 2 3
  • SLRR5B 3 4
  • Podocan-Like Protein 1 3

External Ids for PODNL1 Gene

Summaries for PODNL1 Gene

GeneCards Summary for PODNL1 Gene

PODNL1 (Podocan-Like 1) is a Protein Coding gene. An important paralog of this gene is ECM2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PODNL1 Gene

Genomics for PODNL1 Gene

Genomic Location for PODNL1 Gene

Start:
13,931,187 bp from pter
End:
13,953,392 bp from pter
Size:
22,206 bases
Orientation:
Minus strand

Genomic View for PODNL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PODNL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PODNL1 Gene

Regulatory Elements for PODNL1 Gene

Proteins for PODNL1 Gene

  • Protein details for PODNL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PEZ8-PONL1_HUMAN
    Recommended name:
    Podocan-like protein 1
    Protein Accession:
    Q6PEZ8
    Secondary Accessions:
    • B7Z564
    • Q9H5G9

    Protein attributes for PODNL1 Gene

    Size:
    512 amino acids
    Molecular mass:
    56539 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15657.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};

    Alternative splice isoforms for PODNL1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PODNL1 Gene

Proteomics data for PODNL1 Gene at MOPED

Post-translational modifications for PODNL1 Gene

No data available for DME Specific Peptides for PODNL1 Gene

Domains for PODNL1 Gene

Protein Domains for PODNL1 Gene

UniProtKB/Swiss-Prot:

PONL1_HUMAN
Domain:
  • Contains 1 LRRNT domain.:
    • Q6PEZ8
Family:
  • Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily.:
    • Q6PEZ8
Similarity:
  • Contains 17 LRR (leucine-rich) repeats.:
    • Q6PEZ8
genes like me logo Genes that share domains with PODNL1: view

No data available for Gene Families for PODNL1 Gene

Function for PODNL1 Gene

Gene Ontology (GO) - Molecular Function for PODNL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with PODNL1: view
genes like me logo Genes that share phenotypes with PODNL1: view

miRNA for PODNL1 Gene

miRTarBase miRNAs that target PODNL1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for PODNL1 Gene

Localization for PODNL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PODNL1 Gene

Secreted, extracellular space, extracellular matrix.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PODNL1 Gene COMPARTMENTS Subcellular localization image for PODNL1 gene
Compartment Confidence
extracellular 2
cytosol 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for PODNL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005578 proteinaceous extracellular matrix IEA --
genes like me logo Genes that share ontologies with PODNL1: view

Pathways for PODNL1 Gene

SuperPathways for PODNL1 Gene

No Data Available

Interacting Proteins for PODNL1 Gene

Gene Ontology (GO) - Biological Process for PODNL1 Gene

None

No data available for Pathways by source for PODNL1 Gene

Transcripts for PODNL1 Gene

Unigene Clusters for PODNL1 Gene

Podocan-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PODNL1 Gene

No ASD Table

Relevant External Links for PODNL1 Gene

GeneLoc Exon Structure for
PODNL1
ECgene alternative splicing isoforms for
PODNL1

Expression for PODNL1 Gene

mRNA expression in normal human tissues for PODNL1 Gene

mRNA differential expression in normal tissues according to GTEx for PODNL1 Gene

This gene is overexpressed in Nerve - Tibial (4.8) and Artery - Coronary (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for PODNL1 Gene

SOURCE GeneReport for Unigene cluster for PODNL1 Gene Hs.448497

genes like me logo Genes that share expressions with PODNL1: view

Orthologs for PODNL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PODNL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PODNL1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia PODNL1 36
  • 86.16 (n)
  • 90.54 (a)
PODNL1 37
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PODNL1 36
  • 87.43 (n)
  • 88.33 (a)
PODNL1 37
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Podnl1 36
  • 80 (n)
  • 83.7 (a)
Podnl1 16
Podnl1 37
  • 71 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia PODNL1 37
  • 56 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PODNL1 37
  • 58 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Podnl1 36
  • 79.28 (n)
  • 83.91 (a)
lizard
(Anolis carolinensis)
Reptilia PODNL1 37
  • 49 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii zgc:113307 37
  • 29 (a)
ManyToMany
Species with no ortholog for PODNL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PODNL1 Gene

ENSEMBL:
Gene Tree for PODNL1 (if available)
TreeFam:
Gene Tree for PODNL1 (if available)

Paralogs for PODNL1 Gene

Paralogs for PODNL1 Gene

Selected SIMAP similar genes for PODNL1 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with PODNL1: view

Variants for PODNL1 Gene

Sequence variations from dbSNP and Humsavar for PODNL1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1057193 -- 13,931,448(-) CCCTT(C/T)GGGGG utr-variant-3-prime
rs2305778 -- 13,933,474(+) GGGTC(A/G)GTGTT intron-variant
rs2305779 -- 13,934,220(+) AGAGA(A/G)TCTGG intron-variant
rs3745467 - 13,937,901(-) TGCCC(C/T)GGGCC reference, missense
rs4926320 -- 13,945,897(+) AAAAA(A/C)AACAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PODNL1 Gene

Variant ID Type Subtype PubMed ID
nsv833757 CNV Loss 17160897
nsv911098 CNV Loss 21882294
dgv3738n71 CNV Loss 21882294
nsv911102 CNV Loss 21882294
dgv3739n71 CNV Loss 21882294
dgv3740n71 CNV Loss 21882294
dgv3741n71 CNV Loss 21882294
nsv828451 CNV Loss 20364138

Relevant External Links for PODNL1 Gene

HapMap Linkage Disequilibrium report
PODNL1

Disorders for PODNL1 Gene

No disorders were found for PODNL1 Gene.

No data available for UniProtKB/Swiss-Prot for PODNL1 Gene

Publications for PODNL1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for PODNL1 Gene

Sources for PODNL1 Gene

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