PODN Gene

Aliases
for PODN gene

Previous GC identifers: GC01P052897 GC01P053239 GC01P051643

Summaries
for PODN gene

Genomic Views
for PODN gene

RefSeq DNA sequence:

NC_000001.10  NC_018912.1  NT_032977.9  

SwitchGear Promoter luciferase reporter plasmid: PODN promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PODN

PODN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P053527:  view genomic region     (about GC identifiers)

Proteins
for PODN gene

Explore the universe of human proteins at neXtProt for PODN: NX_Q7Z5L7

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: PODN OriGene Protein Over-expression Lysate: PODN OriGene Custom Protein Services for PODN
	GenScript Custom Purified and Recombinant Proteins Services for PODN
	Novus Biologicals PODN Proteins Novus Biologicals PODN Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for PODN

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for PODN (Podocan)
	Browse OriGene Antibodies OriGene Custom Antibody Services for PODN
	GenScript Custom Superior Antibodies Services for PODN
	Novus Biologicals PODN Antibodies
	Search for Antibodies for PODN at Abcam
	Uscn Antibodies for PODN
	Search ThermoFisher Antibodies for PODN

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for PODN
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for PODN

Protein Domains /
Families
for PODN gene

ProtoNet protein and cluster: Q7Z5L7

Function
for PODN gene

miRNA Products:		OriGene 3'-UTR Clone: PODN Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PODN
		8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate PODN (see all 23):
		hsa-miR-520a-5p hsa-miR-766 hsa-miR-374a* hsa-miR-483-3p hsa-miR-515-5p hsa-miR-124 hsa-miR-149 hsa-miR-155
		SwitchGear 3'UTR luciferase reporter plasmid: PODN 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PODN (see all 4) OriGene shRNA RFP: PODN OriGene siRNA: PODN
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PODN

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for PODN

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PODN (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PODN (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): PODN (NM_024825)
		Sino Biological Human cDNA Clone for PODN
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for PODN
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PODN

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for PODN
		Search LifeMap BioReagents cell lines for PODN

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PODN

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

Pathways & Interactions
for PODN gene

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for PODN gene

Transcripts
for PODN gene

Expression
for PODN gene

PODN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCTGTGGCC

10/12 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 12)
	Tissue Anatomical Compartment Cell			Category (developmental path)
	BoneAutopod Long Bone			Bone
	BoneCaudal Endochondral Bones			Bone
	BoneEndochondral Facial Bones			Bone
	BoneStylopod Long Bone			Bone
	BoneThoracic Rib			Bone
	CartilageMeckel's Cartilage			Cartilage
	KidneyMetanephros			Kidney
	LimbAutopod			Limb
	LimbStylopod			Limb
	LimbZeugopod			Limb
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 2 LifeMap Cells
	Name			Category
	PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)			Heart, Myocardium, Smooth Muscle
	PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PODN Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PODN
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PODN
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PODN

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PODN

Orthologs
for PODN gene

Paralogs
for PODN gene

Paralogs for PODN gene

OGN²  OPTC²  PODNL1²  FMOD²  PRELP²  KERA²  ASPN²  OMD²  

BGN²  DCN²  EPYC²  ECM2²  LUM²  

6 SIMAP similar genes for PODN using alignment to 1 protein entry:     PODN_HUMAN:

PODNL1    SLIT2    MST161    KERA    DCN    BGN

PODN for paralogs           About GeneDecksing

Genomic Variants
for PODN gene

10/534 NCBI SNPs in PODN are shown (see all 534)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1445625031,2		--	53525735(+)	ACCATA/GTGACA	3	--	us2k1		0	--	--	--	--
rs788752161,2	C,F,	--	53525776(+)	TCCAAT/CTTAGA	3	--	us2k1		1		WA	118
rs746072791,2	C,	--	53525777(+)	CCAATA/TTAGAC	3	--	us2k1		0	--	--	--	--
rs1396203271,2		--	53525785(+)	GACATA/TCTGTG	3	--	us2k1		0	--	--	--	--
rs7255091,2	C,F,A,H,	--	53526104(+)	CACACA/GTGGGC	4	--	us2k1		100		NA EA NS MN PA EU CA WA CSA	5265
rs1822548161,2		--	53526135(+)	AAAAGC/TCTATT	4	--	us2k1		0	--	--	--	--
rs1452501691,2		--	53526136(+)	AAAGCC/GTATTT	4	--	us2k1		0	--	--	--	--
rs599498941,2	F,	--	53526169(+)	GGTGTG/ATGGTG	4	--	us2k1		1		WA	118
rs1478964021,2		--	53526185(+)	TGTAGC/TGGGCC	4	--	us2k1		0	--	--	--	--
rs7255101,2	C,F,A,H,	--	53526247(+)	CAGGGC/TTAGGA	4	--	us2k1		96		NS NA EA PA EU CA WA CSA	4958

HapMap Linkage Disequilibrium report for PODN (53527854 - 53551174 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for PODN
     3 CNVs: 9882 48334 2306

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PODN

DNA2.0 Custom Variant and Variant Library Synthesis for PODN

Disorders / Diseases
for PODN gene

Publications
for PODN gene

PubMed articles for PODN gene, integrated from 9 sources (see all 11): (articles sorted by number of sources associating them with PODN)

Utopia: connect your pdf to the dynamic world of online information

1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
3. Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family. (PubMed id 15063725)^{1, 2} Shimizu-Hirota R.... Saruta T. (2004)
4. Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. (PubMed id 12796502)^{1, 2} Ross M.D.... Klotman P.E. (2003)
5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
6. Proteomics characterization of extracellular space components in the human aorta. (PubMed id 20551380)² Didangelos A.... Mayr M. (2010)
7. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
8. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
9. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)² Chen R.... Zou H. (2009)
10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)

External Searches for PODN gene

Genome Databases showing PODN gene

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Specialized Databases showing PODN gene

Products
for PODN gene