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PODN Gene

protein-coding   GIFtS: 53
GCID: GC01P053527

Podocan

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
podocan1 2
Podocan Proteoglycan1 2
SLRR5A2 3
PCAN2

External Ids:    HGNC: 231741   Entrez Gene: 1274352   Ensembl: ENSG000001743487   OMIM: 6086615   UniProtKB: Q7Z5L73   

Export aliases for PODN gene to outside databases

Previous GC identifers: GC01P052897 GC01P053239 GC01P051643


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PODN Gene:
PODN (podocan) is a protein-coding gene. GO annotations related to this gene include collagen binding. An important paralog of this gene is FLRT1.

UniProtKB/Swiss-Prot: PODN_HUMAN, Q7Z5L7
Function: Negatively regulates cell proliferation and cell migration




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PODN gene promoter:
         GATA-3   Sp1   AML1a   MyoD   Olf-1   CUTL1   CREB   RORalpha1   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPODN promoter sequence
   Search Chromatin IP Primers for PODN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PODN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p32.3

PODN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PODN gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P053527:  view genomic region     (about GC identifiers)

Start:
53,527,724 bp from pter      End:
53,551,174 bp from pter
Size:
23,451 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PODN_HUMAN, Q7Z5L7 (See protein sequence)
Recommended Name: Podocan precursor  
Size: 613 amino acids; 68976 Da
Subunit: Binds to type I collagen
Sequence caution: Sequence=AAH28292.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAH72591.1; Type=Erroneous gene model prediction;
Secondary accessions: B4DKN5 B4E373 Q5VVZ2 Q5VVZ3 Q6PIR3 Q6UXL8 Q8N641
Alternative splicing: 4 isoforms:  Q7Z5L7-1   Q7Z5L7-2   Q7Z5L7-3   Q7Z5L7-4   (No signal peptide. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PODN: NX_Q7Z5L7

Explore proteomics data for PODN at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn214, Asn281, Asn299, Asn410

  • See PODN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001186009.1  NP_001186010.1  NP_001186011.1  NP_714914.2  

    ENSEMBL proteins: 
     ENSP00000360555   ENSP00000308315   ENSP00000379212  

    PODN Human Recombinant Protein Products:

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    Novus Biologicals PODN Proteins
    Novus Biologicals PODN Lysates
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    Cloud-Clone Corp. Proteins for PODN

     
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    Search eBioscience for ELISAs for PODN 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

    3 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry Q7Z5L7

    ProtoNet protein and cluster: Q7Z5L7

    1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: PODN_HUMAN, Q7Z5L7
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily
    Similarity: Contains 20 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRNT domain


    Find genes that share domains with PODN           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PODN_HUMAN, Q7Z5L7
    Function: Negatively regulates cell proliferation and cell migration

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005518collagen binding IDA15063725
         
    Find genes that share ontologies with PODN           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for PODN:
     Cell division defect  Increased G2M DNA content  Increased number of mitotic ce 

         1 MGI phenotypic allele for Podn (no phenotypes)

    Find genes that share phenotypes with PODN           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Podntm1Lex for PODN

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PODN
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PODN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PODN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PODN

    miRNA
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    miRTarBase miRNAs that target PODN:
    hsa-mir-335-5p (MIRT017543)

    Block miRNA regulation of human, mouse, rat PODN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PODN (see all 23):
    hsa-miR-520a-5p hsa-miR-766 hsa-miR-374a* hsa-miR-483-3p hsa-miR-515-5p hsa-miR-124 hsa-miR-149 hsa-miR-155
    SwitchGear 3'UTR luciferase reporter plasmidPODN 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PODN
    Predesigned siRNA for gene silencing in human, mouse, rat PODN

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for PODN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): PODN (NM_024825)
    Sino Biological Human cDNA Clone for PODN
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PODN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PODN

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    Browse ESI BIO Cell Lines and PureStem Progenitors for PODN 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PODN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PODN_HUMAN, Q7Z5L7: Isoform 1: Secreted, extracellular space, extracellular matrix
    PODN_HUMAN, Q7Z5L7: Isoform 2: Cytoplasm (Probable)
    PODN_HUMAN, Q7Z5L7: Isoform 3: Cytoplasm (Probable)
    PODN_HUMAN, Q7Z5L7: Isoform 4: Cytoplasm (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    peroxisome2
    cytosol1
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005615extracellular space IDA15063725
    GO:0005737cytoplasm IDA15063725

    Find genes that share ontologies with PODN           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PODN
    Interactions:

        Search GeneGlobe Interaction Network for PODN

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for PODN (ENSP000003083154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAV1ENSP000003391914STRING: ENSP00000339191
    CAB39ENSP000002584184STRING: ENSP00000258418
    CAB39LENSP000002616694STRING: ENSP00000261669
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008285negative regulation of cell proliferation IDA15063725
    GO:0030336negative regulation of cell migration IDA15063725

    Find genes that share ontologies with PODN           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PODN



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PODN gene (4 alternative transcripts): 
    NM_001199080.1  NM_001199081.1  NM_001199082.1  NM_153703.4  

    Unigene Cluster for PODN:

    Podocan
    Hs.586141  [show with all ESTs]
    Unigene Representative Sequence: NM_001199080
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371500(uc001cuw.3 uc010onr.2 uc001cuv.3 uc010ons.2)
    ENST00000312553 ENST00000471210 ENST00000471285 ENST00000490650 ENST00000395871

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PODN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PODN (see all 23):
    hsa-miR-520a-5p hsa-miR-766 hsa-miR-374a* hsa-miR-483-3p hsa-miR-515-5p hsa-miR-124 hsa-miR-149 hsa-miR-155
    SwitchGear 3'UTR luciferase reporter plasmidPODN 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PODN
    Predesigned siRNA for gene silencing in human, mouse, rat PODN
    Clone
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    OriGene clones in human, mouse for PODN (see all 14)
    OriGene ORF clones in mouse, rat for PODN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): PODN (NM_024825)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PODN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PODN
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PODN
    OriGene qSTAR qPCR primer pairs in human, mouse for PODN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PODN
      QuantiTect SYBR Green Assays in human, mouse, rat PODN
      QuantiFast Probe-based Assays in human, mouse, rat PODN

    Additional mRNA sequence: 

    AK296649.1 AK299375.1 AK304599.1 AK314096.1 AY313607.1 AY358294.1 BC024024.1 BC028292.1 
    BC030608.2 

    9 DOTS entries:

    DT.210691  DT.101975113  DT.95366704  DT.100751683  DT.91911683  DT.92378851  DT.92418922  DT.95151952 
    DT.91997013 

    Selected AceView cDNA sequences (see all 96):

    BM682142 BQ019451 AW015571 NM_153703 CA844087 AA255432 AI675397 AW613424 
    BX088959 AI587561 BM510116 CA448225 CA446676 AA346223 AW469388 AI925033 
    BM052964 CA440630 AI279521 BI819230 AI655602 BU617875 CA866306 AI623681 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for PODN (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b
    SP1:                                            -                                                                                 
    SP2:                                                                                                                              
    SP3:                                                                                                                              
    SP4:                                                                                                  -                           
    SP5:                                                                                                                              


    ECgene alternative splicing isoforms for PODN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PODN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCTGTGGCC
    PODN Expression
    About this image


    PODN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 6 entries
             Endochondral Facial Bones
     
     Limb (Muscoskeletal System)    fully expand to see all 4 entries
             Pelvic Girdle
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 2 entries
             Foregut
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Meckel's Cartilage
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Diencephalic Roof Plate
    PODN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PODN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.586141

    UniProtKB/Swiss-Prot: PODN_HUMAN, Q7Z5L7
    Tissue specificity: Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic
    intima (at protein level)

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    QuantiFast Probe-based Assays in human, mouse, rat PODN
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PODN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PODN gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Podn1 , 5 podocan1, 5 87.8(n)1
    92.82(a)1
      4 (50.18 cM)5
    2426081  NM_172874.31  NP_766462.21 
     1080147915 
    chicken
    (Gallus gallus)
    Aves PODN1 podocan 70.31(n)
    75.89(a)
      424647  XM_004936801.1  XP_004936858.1 
    lizard
    (Anolis carolinensis)
    Reptilia PODN6
    podocan
    66(a)
    1 ↔ 1
    4(114907944-114930945)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia podn1 podocan 63.49(n)
    65.42(a)
      101730272  XM_004914012.1  XP_004914069.1 
    zebrafish
    (Danio rerio)
    Actinopterygii podn1 podocan 64.05(n)
    63.43(a)
      100536479  XM_003201237.2  XP_003201285.2 


    ENSEMBL Gene Tree for PODN (if available)
    TreeFam Gene Tree for PODN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PODN gene
    FLRT12  PODNL12  FMOD2  KERA2  PRELP2  FLRT32  OMD2  ASPN2  
    BGN2  DCN2  FLRT22  ECM22  LOC1005090912  LUM2  
    5 SIMAP similar genes for PODN using alignment to 1 protein entry:     PODN_HUMAN:
    PODNL1    SLIT2    MST161    KERA    DCN

    Find genes that share paralogs with PODN           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PODN (see all 671)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1445625031,2
    C--53525735(+) ACCATA/GTGACA 3 -- us2k10--------
    rs788752161,2
    C,F--53525776(+) TCCAAT/CTTAGA 3 -- us2k11Minor allele frequency- C:0.03WA 118
    rs746072791,2
    C--53525777(+) CCAATA/TTAGAC 3 -- us2k10--------
    rs1396203271,2
    --53525785(+) GACATA/TCTGTG 3 -- us2k10--------
    rs7255091,2
    C,F,A,H--53526104(+) CACACA/GTGGGC 4 -- us2k1100Minor allele frequency- G:0.10NA EA NS MN PA EU CA WA CSA 5265
    rs1822548161,2
    --53526135(+) AAAAGC/TCTATT 4 -- us2k10--------
    rs1452501691,2
    --53526136(+) AAAGCC/GTATTT 4 -- us2k10--------
    rs599498941,2
    C,F--53526169(+) GGTGTG/ATGGTG 4 -- us2k11Minor allele frequency- A:0.07WA 118
    rs1478964021,2
    --53526185(+) TGTAGC/TGGGCC 4 -- us2k10--------
    rs7255101,2
    C,F,A,H--53526247(+) CAGGGC/TTAGGA 4 -- us2k196Minor allele frequency- T:0.37NS NA EA PA EU CA WA CSA 4958

    HapMap Linkage Disequilibrium report for PODN (53527724 - 53551174 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for PODN:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv522862CNV Loss19592680
    dgv226n71CNV Loss21882294
    nsv818167CNV Loss17921354
    nsv870582CNV Gain21882294
    nsv516780CNV Gain+Loss19592680
    essv13816CNV CNV17122850
    dgv51e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608661    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for PODN:
    Sebaceous carcinoma

    Find genes that share disorders with PODN           About GenesLikeMe

    Genetic Association Database (GAD): PODN
    Human Genome Epidemiology (HuGE) Navigator: PODN (3 documents)

    Export disorders for PODN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PODN gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with PODN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family. (PubMed id 15063725)1, 2 Shimizu-Hirota R.... Saruta T. (FEBS Lett. 2004)
    5. Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. (PubMed id 12796502)1, 2 Ross M.D.... Klotman P.E. (J. Biol. Chem. 2003)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma. (PubMed id 24043300)1 Hutter R....Klotman P.E. (Circulation 2013)
    8. Proteomics characterization of extracellular space components in the human aorta. (PubMed id 20551380)2 Didangelos A.... Mayr M. (Mol. Cell. Proteomics 2010)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (J. Proteome Res. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 127435 HGNC: 23174 AceView: PODN Ensembl:ENSG00000174348 euGenes: HUgn127435
    ECgene: PODN H-InvDB: PODN

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PODN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PODN gene:
    Search GeneIP for patents involving PODN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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