Aliases for PNPLA8 Gene
- Patatin-Like Phospholipase Domain Containing 8 2 3
- Intracellular Membrane-Associated Calcium-Independent Phospholipase A2 Gamma 3 4
- Patatin-Like Phospholipase Domain-Containing Protein 8 3 4
- PNPLA-Gamma 3 4
- IPLA2-Gamma 3 4
- IPLA2-2 3 4
- IPLA2G 3 4
- Membrane-Associated Calcium-Independent Phospholipase A2 Gamma 3
External Ids for PNPLA8 Gene
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for PNPLA8 Gene
PNPLA8 (Patatin-Like Phospholipase Domain Containing 8) is a Protein Coding gene. Diseases associated with PNPLA8 include weaver syndrome. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include lysophospholipase activity and calcium-independent phospholipase A2 activity. An important paralog of this gene is PLA2G6.
UniProtKB/Swiss-Prot for PNPLA8 Gene
Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.