Aliases for PNPLA4 Gene
External Ids for PNPLA4 Gene
Previous GeneCards Identifiers for PNPLA4 Gene
This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010]
GeneCards Summary for PNPLA4 Gene
PNPLA4 (Patatin Like Phospholipase Domain Containing 4) is a Protein Coding gene. Diseases associated with PNPLA4 include Griscelli Syndrome, Type 2. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Metabolism of xenobiotics by cytochrome P450. GO annotations related to this gene include triglyceride lipase activity. An important paralog of this gene is PNPLA2.
UniProtKB/Swiss-Prot for PNPLA4 Gene