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PNO1 Gene

protein-coding   GIFtS: 49
GCID: GC02P068384

Partner Of NOB1 Homolog (S. Cerevisiae)

(Previous names: KH-type RNA binding protein 1, KH-type RNA-binding protein...)
(Previous symbol: KHRBP1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Partner Of NOB1 Homolog (S. Cerevisiae)1 2     KH-Type RNA Binding Protein 11
KHRBP11 2     RRP202
KH-Type RNA-Binding Protein 11 2     RNA-Binding Protein PNO12
RNA Binding Protein1 2     

External Ids:    HGNC: 327901   Entrez Gene: 569022   Ensembl: ENSG000001159467   UniProtKB: Q9NRX13   

Export aliases for PNO1 gene to outside databases

Previous GC identifers: GC02P068238 GC02P068122


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PNO1 Gene:
PNO1 (partner of NOB1 homolog (S. cerevisiae)) is a protein-coding gene. GO annotations related to this gene include RNA binding.

Gene Wiki entry for PNO1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the PNO1 gene promoter:
         Nkx3-1   C/EBPbeta   p53   Nkx3-1 v1   CUTL1   NF-kappaB   Nkx3-1 v2   Nkx3-1 v3   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPNO1 promoter sequence
   Search Chromatin IP Primers for PNO1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PNO1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p14   Ensembl cytogenetic band:  2p14   HGNC cytogenetic band: 2p14

PNO1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PNO1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P068384:  view genomic region     (about GC identifiers)

Start:
68,384,976 bp from pter      End:
68,403,370 bp from pter
Size:
18,395 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PNO1_HUMAN, Q9NRX1 (See protein sequence)
Recommended Name: RNA-binding protein PNO1  
Size: 252 amino acids; 27924 Da
Secondary accessions: A8K6Q0 Q53G13 Q8WVB8

Explore the universe of human proteins at neXtProt for PNO1: NX_Q9NRX1

Explore proteomics data for PNO1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PNO1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_064528.1  
    ENSEMBL proteins: 
     ENSP00000263657   ENSP00000405892  

    PNO1 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for PNO1 

     
    antibodies-online proteins for PNO1 (10 products) 

     
    Search antibodies-online for peptides for PNO1

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    antibodies-online antibodies for PNO1 (10 products) 

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    Search eBioscience for ELISAs for PNO1 
    antibodies-online kits for PNO1 (10 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR004087 KH_dom
     IPR004088 KH_dom_type_1

    Graphical View of Domain Structure for InterPro Entry Q9NRX1

    ProtoNet protein and cluster: Q9NRX1

    UniProtKB/Swiss-Prot: PNO1_HUMAN, Q9NRX1
    Similarity: Belongs to the PNO1 family
    Similarity: Contains 1 KH domain


    Find genes that share domains with PNO1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with PNO1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for PNO1:
     Increased gamma-H2AX phosphory  Nucleolar pre-40S maturation d 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pno1):
     embryogenesis  immune system  mortality/aging 

    Find genes that share phenotypes with PNO1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Pno1tm1Jwu for PNO1

       genOway: Develop your customized and physiologically relevant rodent model for PNO1

    miRNA
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    Block miRNA regulation of human, mouse, rat PNO1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PNO1 (see all 9):
    hsa-miR-33a* hsa-miR-149 hsa-miR-4251 hsa-miR-3136-5p hsa-miR-590-3p hsa-miR-578 hsa-miR-340 hsa-miR-3145-3p
    SwitchGear 3'UTR luciferase reporter plasmidPNO1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PNO1

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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PNO1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PNO1

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    In Situ Assay
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PNO1_HUMAN, Q9NRX1: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol3
    peroxisome2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--

    Find genes that share ontologies with PNO1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PNO1
    Interactions:

        Search GeneGlobe Interaction Network for PNO1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PNO1 (Q9NRX12, 3 ENSP000002636574) via UniProtKB, MINT, STRING, and/or I2D (see all 216)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP5C1P365422, 3, ENSP000003491424MINT-63713 I2D: score=5 STRING: ENSP00000349142
    KLF6Q996122, 3, ENSP000004199234MINT-64541 I2D: score=5 STRING: ENSP00000419923
    CSNK1EP496742, 3, ENSP000003529294MINT-8252802 I2D: score=4 STRING: ENSP00000352929
    IGFBP5P245932, 3, ENSP000002338134MINT-63609 I2D: score=4 STRING: ENSP00000233813
    RXRGP484432, 3, ENSP000003529004MINT-63772 I2D: score=4 STRING: ENSP00000352900
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PNO1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PNO1 gene: 
    NM_020143.2  

    Unigene Cluster for PNO1:

    Partner of NOB1 homolog (S. cerevisiae)
    Hs.262858  [show with all ESTs]
    Unigene Representative Sequence: NM_020143
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263657(uc002seh.3) ENST00000430742 ENST00000488728
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate PNO1 (see all 9):
    hsa-miR-33a* hsa-miR-149 hsa-miR-4251 hsa-miR-3136-5p hsa-miR-590-3p hsa-miR-578 hsa-miR-340 hsa-miR-3145-3p
    SwitchGear 3'UTR luciferase reporter plasmidPNO1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PNO1
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    Primer
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    OriGene qPCR primer pairs and template standards for PNO1
    OriGene qSTAR qPCR primer pairs in human, mouse for PNO1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PNO1
      QuantiTect SYBR Green Assays in human, mouse, rat PNO1
      QuantiFast Probe-based Assays in human, mouse, rat PNO1

    Additional mRNA sequence: 

    AF164799.1 AF349314.1 AK223118.1 AK225641.1 AK291715.1 AK313204.1 BC008304.1 BC018152.1 
    L48692.1 

    7 DOTS entries:

    DT.453079  DT.100721324  DT.95374254  DT.121612817  DT.95374256  DT.99928479  DT.121034907 

    Selected AceView cDNA sequences (see all 165):

    AI432640 BQ217647 NM_020143 BQ233496 T40124 BM452107 BC018152 AU127353 
    AA338711 CN480757 AA503246 CR597643 BC008304 BX462503 AA281683 CR591407 
    AA583293 BU621762 BM918517 N74894 CD240396 AW631351 BU182365 AI081896 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for PNO1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
    SP1:                    -                                       
    SP2:                    -                 -                     
    SP3:                                                            


    ECgene alternative splicing isoforms for PNO1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PNO1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCAGATTG
    PNO1 Expression
    About this image


    PNO1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Heart (Cardiovascular System)
             Atrioventricular Node
    PNO1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PNO1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.262858

    UniProtKB/Swiss-Prot: PNO1_HUMAN, Q9NRX1
    Tissue specificity: Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary.
    Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon
    and peripheral blood leukocytes

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PNO1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PNO1 gene from Selected species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pno11 , 5 partner of NOB1 homolog (S. cerevisiae)1, 5 87.37(n)1
    92.74(a)1
      11 (9.79 cM)5
    662491  NM_025443.21  NP_079719.11 
     172031985 
    chicken
    (Gallus gallus)
    Aves PNO11 partner of NOB1 homolog (S. cerevisiae) 71.09(n)
    81.33(a)
      769547  NM_001079490.1  NP_001072958.1 
    lizard
    (Anolis carolinensis)
    Reptilia PNO16
    partner of NOB1 homolog (S. cerevisiae)
    76(a)
    1 ↔ 1
    1(126563899-126578403)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC534172 similar to putatative 28 kDa protein 77.74(n)    AY341885.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc657822 hypothetical protein MGC65782 72.28(n)   393520  BC056522.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(1)G00041 lethal (1) G0004 59.89(n)
    69.23(a)
      33033  NM_134543.2  NP_608387.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y53C12B.21 Y53C12B.2 60.96(n)
    66.3(a)
      174534  NM_063698.4  NP_496099.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PNO1(YOR145C)4
    PNO11
    Essential nucleolar protein required for pre-18S rRNA more4
    PNO11
    61.33(n)1
    64.64(a)1
      15(606171-605347)4
    8543171, 4  NP_014788.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G132301 AT3G13230 57.94(n)
    57.07(a)
      820521  NM_112167.2  NP_566450.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g01152001 Os03g0115200 56.22(n)
    56.68(a)
      4331393  NM_001055285.1  NP_001048750.1 


    ENSEMBL Gene Tree for PNO1 (if available)
    TreeFam Gene Tree for PNO1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PNO1 gene

    Find genes that share paralogs with PNO1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for PNO1
    PGOHUM00000247093


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PNO1 (see all 367)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs106904831,2
    C--68383485(+) CAGAG-/CT    
       T
    /TTC
    TTAAC
    2 -- cds1 tfbs31CSA 2
    rs601613451,2
    C--68383487(+) GAGTTCTT/-AACCT 1 -- cds11Minor allele frequency- -:0.00NA 2
    rs1151375141,2
    C,F--68386804(+) AGTCTC/TATCTC 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1380918031,2
    --68386869(+) AAAGTA/GTAAAA 1 -- int10--------
    rs621459481,2
    C--68386900(+) TAACTC/ACTCTT 1 -- int14Minor allele frequency- A:0.28NA WA EA 360
    rs1493376961,2
    C--68386924(+) ATTCTC/TTCATT 1 -- int10--------
    rs1832192651,2
    --68387078(+) GCATCG/TTCAAA 1 -- int10--------
    rs709496751,2
    C--68387097(+) TTTTTT/-GAGAT 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1446758261,2
    C--68387169(+) AATCTC/TGGCTC 1 -- int10--------
    rs1859837771,2
    --68387257(+) CACCAC/TGCCCG 1 -- int10--------

    HapMap Linkage Disequilibrium report for PNO1 (68384976 - 68403370 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for PNO1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv874249CNV Loss21882294
    nsv834251CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PNO1
    DNA2.0 Custom Variant and Variant Library Synthesis for PNO1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PNO1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with PNO1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel human RNA binding protein gene PNO1. (PubMed id 15497447)1, 2, 3 Zhou G.-J.... Yu L. (DNA Seq. 2004)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    5. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 56902 HGNC: 32790 AceView: LOC56902 Ensembl:ENSG00000115946 euGenes: HUgn56902
    ECgene: PNO1 H-InvDB: PNO1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PNO1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PNO1 gene:
    Search GeneIP for patents involving PNO1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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