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Aliases for PNO1 Gene

Aliases for PNO1 Gene

  • Partner Of NOB1 Homolog (S. Cerevisiae) 2 3
  • KH-Type RNA-Binding Protein 1 2 3
  • RNA Binding Protein 2 3
  • KH-Type RNA Binding Protein 1 2
  • RNA-Binding Protein PNO1 3
  • KHRBP1 3
  • RRP20 3

External Ids for PNO1 Gene

Previous HGNC Symbols for PNO1 Gene

  • KHRBP1

Previous GeneCards Identifiers for PNO1 Gene

  • GC02P068238
  • GC02P068384
  • GC02P068122

Summaries for PNO1 Gene

GeneCards Summary for PNO1 Gene

PNO1 (Partner Of NOB1 Homolog (S. Cerevisiae)) is a Protein Coding gene. GO annotations related to this gene include RNA binding.

Gene Wiki entry for PNO1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PNO1 Gene

Genomics for PNO1 Gene

Regulatory Elements for PNO1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for PNO1 Gene

68,157,844 bp from pter
68,176,238 bp from pter
18,395 bases
Plus strand

Genomic View for PNO1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PNO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PNO1 Gene

Proteins for PNO1 Gene

  • Protein details for PNO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein PNO1
    Protein Accession:
    Secondary Accessions:
    • A8K6Q0
    • Q53G13
    • Q8WVB8

    Protein attributes for PNO1 Gene

    252 amino acids
    Molecular mass:
    27924 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PNO1 Gene

Proteomics data for PNO1 Gene at MOPED

Post-translational modifications for PNO1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PNO1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PNO1 Gene

Domains for PNO1 Gene

Protein Domains for PNO1 Gene


Suggested Antigen Peptide Sequences for PNO1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KH domain.
  • Belongs to the PNO1 family.
  • Contains 1 KH domain.
  • Belongs to the PNO1 family.
genes like me logo Genes that share domains with PNO1: view

No data available for Gene Families for PNO1 Gene

Function for PNO1 Gene

Gene Ontology (GO) - Molecular Function for PNO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding --
GO:0044822 poly(A) RNA binding IDA 22681889
genes like me logo Genes that share ontologies with PNO1: view
genes like me logo Genes that share phenotypes with PNO1: view

Animal Models for PNO1 Gene

MGI Knock Outs for PNO1:

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for PNO1 Gene

Localization for PNO1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PNO1 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for PNO1 Gene COMPARTMENTS Subcellular localization image for PNO1 gene
Compartment Confidence
nucleus 5
cytosol 3
peroxisome 2

Gene Ontology (GO) - Cellular Components for PNO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with PNO1: view

Pathways for PNO1 Gene

SuperPathways for PNO1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for PNO1 Gene


No data available for Pathways by source for PNO1 Gene

Transcripts for PNO1 Gene

mRNA/cDNA for PNO1 Gene

Unigene Clusters for PNO1 Gene

Partner of NOB1 homolog (S. cerevisiae):
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PNO1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PNO1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
SP1: -
SP2: - -

Relevant External Links for PNO1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PNO1 Gene

mRNA expression in normal human tissues for PNO1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for PNO1 Gene

This gene is overexpressed in Breast (45.2) and Lung (6.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for PNO1 Gene

SOURCE GeneReport for Unigene cluster for PNO1 Gene Hs.262858

mRNA Expression by UniProt/SwissProt for PNO1 Gene

Tissue specificity: Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary. Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon and peripheral blood leukocytes.
genes like me logo Genes that share expressions with PNO1: view

Expression partners for PNO1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for PNO1 Gene

Orthologs for PNO1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for PNO1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia PNO1 35
  • 87.57 (n)
  • 93.65 (a)
PNO1 36
  • 93 (a)
(Canis familiaris)
Mammalia PNO1 35
  • 87.92 (n)
  • 93.23 (a)
PNO1 36
  • 91 (a)
(Mus musculus)
Mammalia Pno1 35
  • 87.37 (n)
  • 92.74 (a)
Pno1 16
Pno1 36
  • 92 (a)
(Pan troglodytes)
Mammalia PNO1 35
  • 99.34 (n)
  • 99.21 (a)
PNO1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Pno1 35
  • 85.73 (n)
  • 93.2 (a)
(Monodelphis domestica)
Mammalia PNO1 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia PNO1 36
  • 83 (a)
(Gallus gallus)
Aves PNO1 35
  • 71.09 (n)
  • 81.33 (a)
PNO1 36
  • 78 (a)
(Anolis carolinensis)
Reptilia PNO1 36
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia pno1 35
  • 73.05 (n)
  • 82.13 (a)
Str.8210 35
African clawed frog
(Xenopus laevis)
Amphibia MGC53417 35
(Danio rerio)
Actinopterygii pno1 35
  • 66.52 (n)
  • 74.46 (a)
zgc65782 35
pno1 36
  • 68 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8532 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004145 35
  • 59.18 (n)
  • 62.36 (a)
fruit fly
(Drosophila melanogaster)
Insecta l(1)G0004 35
  • 59.89 (n)
  • 69.23 (a)
l(1)G0004 36
  • 57 (a)
(Caenorhabditis elegans)
Secernentea Y53C12B.2 35
  • 60.96 (n)
  • 66.3 (a)
Y53C12B.2 36
  • 45 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR390C 35
  • 57.09 (n)
  • 64.09 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C06446g 35
  • 60.37 (n)
  • 61.22 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PNO1 35
  • 61.33 (n)
  • 64.64 (a)
PNO1 36
  • 44 (a)
PNO1 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G13230 35
  • 57.94 (n)
  • 57.07 (a)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.10303 35
(Hordeum vulgare)
Liliopsida Hv.699 35
(Oryza sativa)
Liliopsida Os03g0115200 35
  • 56.22 (n)
  • 56.68 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.11273 35
bread mold
(Neurospora crassa)
Ascomycetes NCU07956 35
  • 53.33 (n)
  • 54.36 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rbp28 35
  • 57.64 (n)
  • 58.13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 69 (a)
Species with no ortholog for PNO1:
  • Actinobacteria (Mycobacterium tuberculosis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PNO1 Gene

Gene Tree for PNO1 (if available)
Gene Tree for PNO1 (if available)

Paralogs for PNO1 Gene Pseudogenes for PNO1 Gene

genes like me logo Genes that share paralogs with PNO1: view

No data available for Paralogs for PNO1 Gene

Variants for PNO1 Gene

Sequence variations from dbSNP and Humsavar for PNO1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1060842 -- 68,174,880(+) AACCA(G/T)CTGAA utr-variant-3-prime
rs1137930 -- 68,161,691(+) TGTAA(A/G)GAAAC reference, synonymous-codon
rs1448924 -- 68,173,110(+) tttAA(A/G)AGAGA intron-variant
rs1448925 -- 68,173,238(+) TCTCA(A/G)ACTCC intron-variant
rs3213962 -- 68,162,537(+) CTTTT(C/G)TTGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PNO1 Gene

Variant ID Type Subtype PubMed ID
nsv834251 CNV Loss 17160897
nsv874249 CNV Loss 21882294

Relevant External Links for PNO1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PNO1 Gene

Disorders for PNO1 Gene

No disorders were found for PNO1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for PNO1 Gene

Publications for PNO1 Gene

  1. Cloning and characterization of a novel human RNA binding protein gene PNO1. (PMID: 15497447) Zhou G.-J. … Yu L. (DNA Seq. 2004) 2 3 4
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu R.-M. … Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for PNO1 Gene

Sources for PNO1 Gene

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