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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PNO1 Gene

protein-coding   GIFtS: 48
GCID: GC02P068384

Partner Of NOB1 Homolog (S. Cerevisiae)

(Previous names: KH-type RNA binding protein 1, KH-type RNA-binding protein...)
(Previous symbol: KHRBP1)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Partner Of NOB1 Homolog (S. Cerevisiae)1 2     KH-Type RNA Binding Protein 11
KHRBP11 2     RRP202
KH-Type RNA-Binding Protein 11 2     RNA-Binding Protein PNO12
RNA Binding Protein1 2     

External Ids:    HGNC: 327901   Entrez Gene: 569022   Ensembl: ENSG000001159467   UniProtKB: Q9NRX13   

Export aliases for PNO1 gene to outside databases

Previous GC identifers: GC02P068238 GC02P068122


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PNO1 Gene: 
PNO1 (partner of NOB1 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with PNO1 include prostatitis. GO annotations related to this gene include RNA binding.

Gene Wiki entry for PNO1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PNO1 gene promoter:
         Nkx3-1   C/EBPbeta   p53   Nkx3-1 v1   CUTL1   NF-kappaB   Nkx3-1 v2   Nkx3-1 v3   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPNO1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PNO1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PNO1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p14   Ensembl cytogenetic band:  2p14   HGNC cytogenetic band: 2p14

PNO1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PNO1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P068384:  view genomic region     (about GC identifiers)

Start:
68,384,976 bp from pter      End:
68,403,370 bp from pter
Size:
18,395 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PNO1_HUMAN, Q9NRX1 (See protein sequence)
Recommended Name: RNA-binding protein PNO1  
Size: 252 amino acids; 27924 Da
Subcellular location: Nucleus, nucleolus
Secondary accessions: A8K6Q0 Q53G13 Q8WVB8

Explore the universe of human proteins at neXtProt for PNO1: NX_Q9NRX1

Explore proteomics data for PNO1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NRX1

  • PNO1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PNO1 Protein Expression
    REFSEQ proteins: NP_064528.1  
    ENSEMBL proteins: 
     ENSP00000263657   ENSP00000405892  

    Human Recombinant Protein Products for PNO1: 
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    Novus Biologicals PNO1 Protein
    Novus Biologicals PNO1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA15497447

    PNO1 for ontologies           About GeneDecksing



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    LSBio Antibodies in human, mouse, rat for PNO1 

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    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR004087 KH_dom
     IPR004088 KH_dom_type_1

    Graphical View of Domain Structure for InterPro Entry Q9NRX1

    ProtoNet protein and cluster: Q9NRX1

    UniProtKB/Swiss-Prot: PNO1_HUMAN, Q9NRX1
    Similarity: Belongs to the PNO1 family
    Similarity: Contains 1 KH domain


    PNO1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
         
    PNO1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for PNO1:
     Increased gamma-H2AX phosphory  Nucleolar pre-40S maturation d 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pno1):
     embryogenesis  immune system  mortality/aging 

    PNO1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Pno1tm1Jwu for PNO1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for PNO1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PNO1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PNO1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PNO1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PNO1
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate PNO1 (see all 9):
    hsa-miR-33a* hsa-miR-149 hsa-miR-4251 hsa-miR-3136-5p hsa-miR-590-3p hsa-miR-578 hsa-miR-340 hsa-miR-3145-3p
    SwitchGear 3'UTR luciferase reporter plasmidPNO1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PNO1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PNO1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/76 Interacting proteins for PNO1 (Q9NRX12, 3 ENSP000002636574) via UniProtKB, MINT, STRING, and/or I2D (see all 76)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK1EP496742, 3, ENSP000003529294MINT-8252802 I2D: score=4 STRING: ENSP00000352929
    IGFBP5P245932, 3, ENSP000002338134MINT-63609 I2D: score=4 STRING: ENSP00000233813
    FRZBQ927652, 3, ENSP000002951134MINT-8255481 I2D: score=2 STRING: ENSP00000295113
    GSTP1P092112, 3MINT-63446 I2D: score=5 
    SGSM2O431472, 3MINT-64872 I2D: score=5 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PNO1

    Search CenterWatch for drugs/clinical trials and news about PNO1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PNO1 gene: 
    NM_020143.2  

    Unigene Cluster for PNO1:

    Partner of NOB1 homolog (S. cerevisiae)
    Hs.262858  [show with all ESTs]
    Unigene Representative Sequence: NM_020143
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263657(uc002seh.3) ENST00000430742 ENST00000488728
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PNO1
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate PNO1 (see all 9):
    hsa-miR-33a* hsa-miR-149 hsa-miR-4251 hsa-miR-3136-5p hsa-miR-590-3p hsa-miR-578 hsa-miR-340 hsa-miR-3145-3p
    SwitchGear 3'UTR luciferase reporter plasmidPNO1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for PNO1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PNO1
    Clone
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    OriGene clones in human, mouse for PNO1 (see all 8)
    OriGene ORF clones in mouse, rat for PNO1
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    GenScript: all cDNA clones in your preferred vector: PNO1 (NM_020143)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PNO1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PNO1
    Sirion Biotech Customized lentivirus for stable overexpression of PNO1 
                         Customized lentivirus expression plasmids for stable overexpression of PNO1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PNO1
    OriGene qSTAR qPCR primer pairs in human, mouse for PNO1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PNO1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PNO1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PNO1

    Additional mRNA sequence: 

    AF164799.1 AF349314.1 AK223118.1 AK225641.1 AK291715.1 AK313204.1 BC008304.1 BC018152.1 
    L48692.1 

    7 DOTS entries:

    DT.453079  DT.100721324  DT.95374254  DT.121612817  DT.95374256  DT.99928479  DT.121034907 

    24/165 AceView cDNA sequences (see all 165):

    AI432640 AA503246 AA338711 CD240396 CR591407 BC008304 BQ233496 BX462503 
    BQ217647 N74894 BC018152 AA281683 CR597643 T40124 BU182365 AA583293 
    CN480757 AU127353 BM918517 BU621762 NM_020143 BM452107 AW631351 AW662565 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for PNO1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
    SP1:                    -                                       
    SP2:                    -                 -                     
    SP3:                                                            


    ECgene alternative splicing isoforms for PNO1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PNO1 expression in normal human tissues (normalized intensities)      PNO1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCAGATTG
    PNO1 Expression
    About this image


    PNO1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Superior Cervical Ganglion   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Trigeminal Ganglion   
     
     Heart (Cardiovascular System)
             Atrioventricular Node
     
     Skeletal Muscle (Respiratory System)
             diaphragm   
     
     Lower Urinary Tract (Urinary System)
             bladder   

    See PNO1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PNO1

    SOURCE GeneReport for Unigene cluster: Hs.262858

    UniProtKB/Swiss-Prot: PNO1_HUMAN, Q9NRX1
    Tissue specificity: Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary.
    Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon
    and peripheral blood leukocytes

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PNO1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PNO1 gene from 10/28 species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pno11 , 5 partner of NOB1 homolog (S. cerevisiae)1, 5 87.37(n)1
    92.74(a)1
      11 (9.79 cM)5
    662491  NM_025443.21  NP_079719.11 
     172031985 
    chicken
    (Gallus gallus)
    Aves PNO11 partner of NOB1 homolog (S. cerevisiae) 70.8(n)
    79.75(a)
      769547  NM_001079490.1  NP_001072958.1 
    lizard
    (Anolis carolinensis)
    Reptilia PNO16
    partner of NOB1 homolog (S. cerevisiae)
    76(a)
    1 ↔ 1
    1(126563899-126578403)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC534172 similar to putatative 28 kDa protein 77.74(n)    AY341885.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc657822 hypothetical protein MGC65782 72.28(n)   393520  BC056522.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(1)G00041 lethal (1) G0004 57.04(n)
    61.64(a)
      33033  NM_134543.2  NP_608387.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y53C12B.21 Protein Y53C12B.2 60.93(n)
    66.67(a)
      174534  NM_063698.3  NP_496099.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PNO1(YOR145C)4
    PNO11
    Essential nucleolar protein required for pre-18S rRNA more4
    Pno1p1
    61.33(n)1
    64.64(a)1
      15(606171-605347)4
    8543171, 4  NP_014788.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G132301 RNA-binding protein PNO1 57.94(n)
    57.07(a)
      820521  NM_112167.2  NP_566450.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g01152001 hypothetical protein 56.22(n)
    56.68(a)
      4331393  NM_001055285.1  NP_001048750.1 


    ENSEMBL Gene Tree for PNO1 (if available)
    TreeFam Gene Tree for PNO1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PNO1 gene

    PNO1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PNO1
    PGOHUM00000247093


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/367 SNPs in PNO1 are shown (see all 367)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0298154
    ----see VAR_0298152 G A mis40--------
    VAR_0298144
    ----see VAR_0298142 R G mis40--------
    rs106904831,2
    C--68383485(+) CAGAG-/CT    
       T
    /TTC
    TTAAC
    2 -- cds1 tfbs31CSA 2
    rs601613451,2
    C--68383487(+) GAGTTCTT/-AACCT 1 -- cds11Minor allele frequency- -:0.00NA 2
    rs1151375141,2
    C,F--68386804(+) AGTCTC/TATCTC 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1380918031,2
    --68386869(+) AAAGTA/GTAAAA 1 -- int10--------
    rs621459481,2
    C--68386900(+) TAACTC/ACTCTT 1 -- int14Minor allele frequency- A:0.28NA WA EA 360
    rs1493376961,2
    C--68386924(+) ATTCTC/TTCATT 1 -- int10--------
    rs1832192651,2
    --68387078(+) GCATCG/TTCAAA 1 -- int10--------
    rs709496751,2
    C--68387097(+) TTTTTT/-GAGAT 1 -- int11Minor allele frequency- -:0.00NA 2

    HapMap Linkage Disequilibrium report for PNO1 (68384976 - 68403370 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for PNO1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv874249CNV Loss21882294
    nsv834251CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PNO1
    DNA2.0 Custom Variant and Variant Library Synthesis for PNO1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for PNO1:    About MalaCards
    prostatitis    


    PNO1 for disorders           About GeneDecksing


    Export disorders for PNO1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PNO1 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with PNO1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel human RNA binding protein gene PNO1. (PubMed id 15497447)1, 2, 3 Zhou G.J.... Yu L. (2004)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    5. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56902 HGNC: 32790 AceView: LOC56902 Ensembl:ENSG00000115946 euGenes: HUgn56902
    ECgene: PNO1 H-InvDB: PNO1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PNO1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PNO1 gene:
    Search GeneIP for patents involving PNO1

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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