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Aliases for PNMA6A Gene

Aliases for PNMA6A Gene

  • Paraneoplastic Ma Antigen Family Member 6A 2 3
  • Paraneoplastic Ma Antigen Family Member 6C 2 3
  • PNMA6C 3 4
  • Paraneoplastic Antigen-Like 6A Related Protein 3
  • Paraneoplastic Antigen-Like Protein 6C 3
  • Paraneoplastic Antigen Like 6A 2
  • Paraneoplastic Antigen Like 6C 2
  • PNMA6 3
  • MA6 3

External Ids for PNMA6A Gene

Previous HGNC Symbols for PNMA6A Gene

  • PNMA6C

Previous GeneCards Identifiers for PNMA6A Gene

  • GC0XP150859
  • GC0XP151911
  • GC0XP151991
  • GC0XP152338

Summaries for PNMA6A Gene

GeneCards Summary for PNMA6A Gene

PNMA6A (Paraneoplastic Ma Antigen Family Member 6A) is a Protein Coding gene. An important paralog of this gene is ZCCHC12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PNMA6A Gene

Genomics for PNMA6A Gene

Regulatory Elements for PNMA6A Gene

Genomic Location for PNMA6A Gene

153,072,414 bp from pter
153,075,019 bp from pter
2,606 bases
Plus strand

Genomic View for PNMA6A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PNMA6A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PNMA6A Gene

Proteins for PNMA6A Gene

  • Protein details for PNMA6A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Paraneoplastic antigen-like protein 6A
    Protein Accession:
    Secondary Accessions:
    • A8K1G4
    • D3DWT8
    • P0CW26
    • Q96A40

    Protein attributes for PNMA6A Gene

    399 amino acids
    Molecular mass:
    43875 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PNMA6A Gene

Proteomics data for PNMA6A Gene at MOPED

Post-translational modifications for PNMA6A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PNMA6A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PNMA6A Gene

Domains & Families for PNMA6A Gene

Gene Families for PNMA6A Gene

Protein Domains for PNMA6A Gene


Suggested Antigen Peptide Sequences for PNMA6A Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the PNMA family.
  • Belongs to the PNMA family.
genes like me logo Genes that share domains with PNMA6A: view

Function for PNMA6A Gene

Gene Ontology (GO) - Molecular Function for PNMA6A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with PNMA6A: view

Phenotypes for PNMA6A Gene

GenomeRNAi human phenotypes for PNMA6A:
genes like me logo Genes that share phenotypes with PNMA6A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PNMA6A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PNMA6A Gene

Localization for PNMA6A Gene

Subcellular locations from

Jensen Localization Image for PNMA6A Gene COMPARTMENTS Subcellular localization image for PNMA6A gene
Compartment Confidence
chloroplast 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PNMA6A Gene

Pathways & Interactions for PNMA6A Gene

SuperPathways for PNMA6A Gene

No Data Available

Interacting Proteins for PNMA6A Gene

Selected Interacting proteins: P0CW24-PNM6A_HUMAN for PNMA6A Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for PNMA6A Gene


No data available for Pathways by source and SIGNOR curated interactions for PNMA6A Gene

Drugs & Compounds for PNMA6A Gene

No Compound Related Data Available

Transcripts for PNMA6A Gene

mRNA/cDNA for PNMA6A Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(41) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PNMA6A Gene

Paraneoplastic Ma antigen family member 6A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PNMA6A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PNMA6A Gene

No ASD Table

Relevant External Links for PNMA6A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PNMA6A Gene

mRNA expression in normal human tissues for PNMA6A Gene

mRNA differential expression in normal tissues according to GTEx for PNMA6A Gene

This gene is overexpressed in Brain - Cortex (x6.8), Brain - Substantia nigra (x6.2), Brain - Frontal Cortex (BA9) (x5.5), Brain - Amygdala (x5.1), Brain - Hypothalamus (x4.8), and Brain - Anterior cingulate cortex (BA24) (x4.2).

Protein differential expression in normal tissues from HIPED for PNMA6A Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PNMA6A Gene

SOURCE GeneReport for Unigene cluster for PNMA6A Gene Hs.721963

mRNA Expression by UniProt/SwissProt for PNMA6A Gene

Tissue specificity: Expressed in the brain.
genes like me logo Genes that share expression patterns with PNMA6A: view

Protein tissue co-expression partners for PNMA6A Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for PNMA6A Gene

Orthologs for PNMA6A Gene

This gene was present in the common ancestor of mammals.

Orthologs for PNMA6A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC526946 35
  • 63.18 (n)
  • 49.83 (a)
-- 36
  • 43 (a)
(Canis familiaris)
Mammalia LOC100687496 35
  • 64.78 (n)
  • 52.65 (a)
-- 36
  • 72 (a)
(Pan troglodytes)
Mammalia PNMA6C 35
  • 99.63 (n)
  • 98.9 (a)
Species with no ortholog for PNMA6A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PNMA6A Gene

Gene Tree for PNMA6A (if available)
Gene Tree for PNMA6A (if available)

Paralogs for PNMA6A Gene

Paralogs for PNMA6A Gene

(8) SIMAP similar genes for PNMA6A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PNMA6A: view

Variants for PNMA6A Gene

Sequence variations from dbSNP and Humsavar for PNMA6A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2301186 -- 153,074,580(+) CGTAT(C/G)GTGAG utr-variant-3-prime
rs2301187 -- 153,074,812(+) CTGAG(G/T)TTCCC utr-variant-3-prime
rs6627743 -- 153,071,338(-) CATCA(C/T)GGGAG upstream-variant-2KB
rs41311368 -- 153,074,687(+) CCCCA(G/T)CGCAG utr-variant-3-prime
rs58467951 -- 153,075,478(+) GACTC(C/G)GCGGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for PNMA6A Gene

Variant ID Type Subtype PubMed ID
nsv7467 OTHER Inversion 18451855
essv6402 CNV CNV 17122850
dgv2494e1 CNV Complex 17122850
nsv9997 CNV Gain 18304495
esv33199 CNV Gain+Loss 17666407

Relevant External Links for PNMA6A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PNMA6A Gene

Disorders for PNMA6A Gene

Relevant External Links for PNMA6A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with PNMA6A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PNMA6A Gene

Publications for PNMA6A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Paraneoplastic antigen-like 5 gene (PNMA5) is preferentially expressed in the association areas in a primate specific manner. (PMID: 19366867) Takaji M. … Yamamori T. (Cereb. Cortex 2009) 67
  5. A functional -1 ribosomal frameshift signal in the human paraneoplastic Ma3 gene. (PMID: 16407312) Wills N.M. … Atkins J.F. (J. Biol. Chem. 2006) 67

Products for PNMA6A Gene

Sources for PNMA6A Gene

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