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PNLIPRP2 Gene

protein-coding   GIFtS: 60
GCID: GC10P118370

Pancreatic Lipase-Related Protein 2

  Search for PNLIPRP2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Pancreatic Lipase-Related Protein 21 2     galactolipase2
PLRP22 3 5     EC 3.1.1.263
PL-RP22 3     Galactolipase3
EC 3.1.1.33 8     EC 3.1.18

External Ids:    HGNC: 91571   Entrez Gene: 54082   Ensembl: ENSG000001658627   OMIM: 6044235   UniProtKB: P543173   

Export aliases for PNLIPRP2 gene to outside databases

Previous GC identifers: GC10P117299 GC10P117624 GC10P118511 GC10P118045 GC10P112007


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PNLIPRP2 Gene:
PNLIPRP2 (pancreatic lipase-related protein 2) is a protein-coding gene. GO annotations related to this gene include phospholipase activity and calcium ion binding. An important paralog of this gene is LIPH.

UniProtKB/Swiss-Prot: LIPR2_HUMAN, P54317
Function: Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts
preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the PNLIPRP2 gene promoter:
         p53   AML1a   FOXO3   LUN-1   NF-E2 p45   GATA-1   FOXO3b   FOXO3a   NF-E2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPNLIPRP2 promoter sequence
   Search Chromatin IP Primers for PNLIPRP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PNLIPRP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.3   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q26.12

PNLIPRP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PNLIPRP2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P118370:  view genomic region     (about GC identifiers)

Start:
118,380,465 bp from pter      End:
118,404,654 bp from pter
Size:
24,190 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: LIPR2_HUMAN, P54317 (See protein sequence)
Recommended Name: Pancreatic lipase-related protein 2 precursor  
Size: 469 amino acids; 51947 Da
2 PDB 3D structures from and Proteopedia for PNLIPRP2:
2OXE (3D)        2PVS (3D)    
Secondary accessions: A8K627 Q6IB55

Explore the universe of human proteins at neXtProt for PNLIPRP2: NX_P54317

Explore proteomics data for PNLIPRP2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn353, Asn428
  • Selected DME Specific Peptides for PNLIPRP2 (P54317) (see all 11)
     GCPKMGH  DFFPNGG  RLDPSDA  GLDPAGP 


    See PNLIPRP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005387.2  
    ENSEMBL proteins: 
     ENSP00000424858   ENSP00000446346  
    Reactome Protein details: P54317

    PNLIPRP2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR001024 PLAT/LH2_dom
     IPR008976 Lipase_LipOase
     IPR000734 Lipase
     IPR016272 Lipoprotein_lipase_LIPH
     IPR002331 Lipase_panc

    Graphical View of Domain Structure for InterPro Entry P54317

    ProtoNet protein and cluster: P54317

    4 Blocks protein domains:
    IPB000734 Lipase
    IPB001024 Lipoxygenase
    IPB002331 Pancreatic lipase signature
    IPB008262 Lipase


    UniProtKB/Swiss-Prot: LIPR2_HUMAN, P54317
    Similarity: Belongs to the AB hydrolase superfamily. Lipase family
    Similarity: Contains 1 PLAT domain


    Find genes that share domains with PNLIPRP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LIPR2_HUMAN, P54317
    Function: Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts
    preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis
    Catalytic activity: Triacylglycerol + H(2)O = diacylglycerol + a carboxylate
    Catalytic activity: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H(2)O = 3-beta-D-galactosyl-sn-glycerol + 2
    carboxylates

         Enzyme Numbers (IUBMB): EC 3.1.1.31 2 EC 3.1.1.261 EC 3.1.12

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004620phospholipase activity IDA18702514
    GO:0004806triglyceride lipase activity IEA--
    GO:0005509calcium ion binding IDA18702514
    GO:0005515protein binding ----
    GO:0047372acylglycerol lipase activity IDA18702514
         
    Find genes that share ontologies with PNLIPRP2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for PNLIPRP2:
     Increased gamma-H2AX phosphory 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pnliprp2):
     digestive/alimentary  growth/size/body  hematopoietic system  homeostasis/metabolism  immune system 

    Find genes that share phenotypes with PNLIPRP2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PNLIPRP2
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    LIPR2_HUMAN, P54317: Secreted

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IDA18702514

    Find genes that share ontologies with PNLIPRP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PNLIPRP2 About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    Metabolic pathways0.38
    2Fat digestion and absorption
    Digestion of dietary lipid0.00
    Fat digestion and absorption
    3Lipoprotein metabolism
    Lipid digestion, mobilization, and transport0.59
    4triacylglycerol degradation
    triacylglycerol degradation
    5Pancreatic secretion
    Pancreatic secretion


    Find genes that share SuperPaths with PNLIPRP2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for PNLIPRP2
        triacylglycerol degradation


    1 Reactome Pathway for PNLIPRP2
        Digestion of dietary lipid


    4 Kegg Pathways  (Kegg details for PNLIPRP2):
        Glycerolipid metabolism
    Metabolic pathways
    Pancreatic secretion
    Fat digestion and absorption

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PNLIPRP2
    Interactions:

        Search GeneGlobe Interaction Network for PNLIPRP2

    1 Interacting protein for PNLIPRP2 (P543173) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLPSP041183I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006629lipid metabolic process ----
    GO:0006641triglyceride metabolic process TAS1379598
    GO:0006968cellular defense response ----
    GO:0007586digestion ----
    GO:0009395phospholipid catabolic process IDA18702514

    Find genes that share ontologies with PNLIPRP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PNLIPRP2 (LIPR2)

    Selected HMDB Compounds for PNLIPRP2 (see all 1142)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Arachidic acidArachate (see all 10)506-30-9--
    Arachidonic acid5,8,11,14-Eicosatetraenoic acid (see all 16)506-32-1--
    DG(14:0/14:0/0:0)DAG(14:0/14:0) (see all 9)----
    DG(14:0/14:1(9Z)/0:0)DAG(14:0/14:1) (see all 15)----
    DG(14:0/15:0/0:0)Diacylglycerol(29:0) (see all 9)----
    DG(14:0/16:0/0:0)DAG(30:0) (see all 9)----
    DG(14:0/16:1(9Z)/0:0)DG(30:1) (see all 15)----
    DG(14:0/18:0/0:0)DG(14:0/18:0) (see all 9)----
    DG(14:0/18:1(11Z)/0:0)Diacylglycerol (see all 15)----
    DG(14:0/18:1(9Z)/0:0)1-myristoyl-2-oleoyl-sn-glycerol (see all 15)----

    1 DrugBank Compound for PNLIPRP2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Decylamine-N,N-Dimethyl-N-Oxide-- --target--10592235

    1 Novoseek inferred chemical compound relationship for PNLIPRP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lipid 33.3 14 19548271 (4), 15466464 (1), 20083229 (1), 19325035 (1) (see all 5)



    Find genes that share compounds with PNLIPRP2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PNLIPRP2 gene: 
    NM_005396.4  

    Unigene Cluster for PNLIPRP2:

    Pancreatic lipase-related protein 2
    Hs.423598  [show with all ESTs]
    Unigene Representative Sequence: NM_005396
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298771 ENST00000444825 ENST00000429325 ENST00000433618 ENST00000537242(uc009xyu.1 uc009xyv.1 uc001lcq.3)

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    Additional mRNA sequence: 

    AK291492.1 AK307745.1 AK308508.1 AK308511.1 AK308521.1 BC005989.2 CR456949.1 M93284.1 

    6 DOTS entries:

    DT.108899  DT.100031039  DT.100746252  DT.100748713  DT.121282590  DT.95275020 

    Selected AceView cDNA sequences (see all 168):

    BM264329 BM310846 BM264027 BU951183 CA775453 CA868352 AA148863 CA772522 
    BM264413 BM503865 BQ271410 CA868106 CA774467 CA952672 BM352795 CR456949 
    BU951084 BE969861 BG654448 BU949602 CA774701 BG656561 BU069247 BM510010 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PNLIPRP2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
    SP1:                                                      
    SP2:                                                      
    SP3:                                                      
    SP4:                                                      


    ECgene alternative splicing isoforms for PNLIPRP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PNLIPRP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCAAGAAAA
    PNLIPRP2 Expression
    About this image


    PNLIPRP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Duct Cells Pancreatic Ducts
             Islets of Langerhans
     
     Epithelial Cells
             Duct Cells Pancreatic Ducts
     
     Liver (Hepatobiliary System)
             Mesothelial Cells Hepatic Mesenchyme
    PNLIPRP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PNLIPRP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.423598

    UniProtKB/Swiss-Prot: LIPR2_HUMAN, P54317
    Tissue specificity: Pancreas

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PNLIPRP2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pnliprp21 , 5 pancreatic lipase-related protein 21, 5 79.63(n)1
    75.85(a)1
      19 (54.50 cM)5
    189471  NM_011128.21  NP_035258.21 
     587597235 
    chicken
    (Gallus gallus)
    Aves PNLIP6
    Gallus gallus pancreatic lipase (PNLIP), mRNA.
    60(a)
    1 → many
    6(28388274-28399269)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    61(a)
    1 → many
    GL343206.1(2017129-2041833)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BC064243.12   -- 72.72(n)    BC064243.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01114051.16
    Uncharacterized protein
    21(a)
    many ↔ many
    25(33034-38787) ENSDARG00000090486
    fruit fly
    (Drosophila melanogaster)
    Insecta CG64723 lipase 36(a)
    (best of 8)
        --


    ENSEMBL Gene Tree for PNLIPRP2 (if available)
    TreeFam Gene Tree for PNLIPRP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PNLIPRP2 gene
    LIPH2  LIPC2  LIPG2  PNLIPRP32  LPL2  PNLIP2  LIPI2  PLA1A2  
    PNLIPRP12  
    10 SIMAP similar genes for PNLIPRP2 using alignment to 2 protein entries:     LIPR2_HUMAN (see all proteins):
    DKFZp779I1240    PNLIP    PNLIPRP1    PNLIPRP3    LIPH    LPL
    LIPI    PLA1A    LIPC    LIPG

    Find genes that share paralogs with PNLIPRP2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for PNLIPRP2
    PGOHUM00000262172


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PNLIPRP2 (see all 232)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs350912031,2
    C--118379722(+) CGCCA-/ATTCTC 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1416318241,2
    C--118380503(+) AGGGCC/TCCATG 1 -- int10--------
    rs3700112551,2
    C--118380558(+) GGGACA/GTGGCC 1 -- int10--------
    rs1121760201,2
    C,F--118381449(+) TCCTCC/TGGGAG 1 -- int11Minor allele frequency- T:0.02NA 120
    rs3763156381,2
    C--118382767(+) TTTTTA/CAAAGA 1 -- int10--------
    rs3775786591,2
    C--118383513(+) GGCAGA/GAACCC 2 E G mis10--------
    rs32170861,2
    C--118383824(+) CACAC-/AC/CA 
            
    TGGTG
    1 -- int10--------
    rs3679481431,2
    C--118385520(+) AGACAA/C/TGCTTC 3 S R C mis10--------
    rs1839442991,2
    --118385974(+) CTATAC/TATGCA 1 -- int10--------
    rs3731773291,2
    C--118387949(+) AAAGA-/AGGAGAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for PNLIPRP2 (118380465 - 118404654 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for PNLIPRP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1523619CNV Insertion17803354

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing PNLIPRP2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604423    OMIM disorders: --


    Find genes that share disorders with PNLIPRP2           About GenesLikeMe

    Genetic Association Database (GAD): PNLIPRP2
    Human Genome Epidemiology (HuGE) Navigator: PNLIPRP2 (1 document)

    Export disorders for PNLIPRP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PNLIPRP2 gene, integrated from 10 sources (see all 49):
    (articles sorted by number of sources associating them with PNLIPRP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity. (PubMed id 1379598)1, 2, 3 Giller T.... Hunziker W. (J. Biol. Chem. 1992)
    2. Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation. (PubMed id 18702514)1, 2, 9 Eydoux C.... Carriere F. (Biochemistry 2008)
    3. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1, 4 Demirkan A....Schmitz G. (PLoS Genet. 2012)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Lipolysis of natural long chain and synthetic medium chain galactolipids by pancreatic lipase-related protein 2. (PubMed id 20083229)2, 9 Amara S.... Carriere F. (Biochim. Biophys. Acta 2010)
    7. Lipid-dependent cytotoxicity by the lipase PLRP2 and by PLRP2-positive cytotoxic T lymphocytes (CTLs). (PubMed id 19548271)1, 9 Alves B.N....Hudig D. (Cell Biochem. Funct. 2009)
    8. Individual and combined action of pancreatic lipase and pancreatic lipase-related proteins 1 and 2 on native versus homogenized milk fat globules. (PubMed id 19824014)2, 9 Berton A.... Crenon I. (Mol. Nutr. Food Res. 2009)
    9. Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells. (PubMed id 17401110)1, 9 Eydoux C....De Caro A. (J. Lipid Res. 2007)
    10. Human pancreatic lipase-related protein 2 is a galactolipase. (PubMed id 15287741)1, 9 Sias B....CarriA"re F. (Biochemistry 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5408 HGNC: 9157 AceView: PNLIPRP2 Ensembl:ENSG00000165862 euGenes: HUgn5408
    ECgene: PNLIPRP2 Kegg: 5408 H-InvDB: PNLIPRP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PNLIPRP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PNLIPRP2 gene:
    Search GeneIP for patents involving PNLIPRP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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