Aliases for PNLIP Gene
External Ids for PNLIP Gene
Previous GeneCards Identifiers for PNLIP Gene
This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
GeneCards Summary for PNLIP Gene
PNLIP (Pancreatic Lipase) is a Protein Coding gene. Diseases associated with PNLIP include pancreatic colipase deficiency and pancreatic lipase deficiency. Among its related pathways are Signaling by GPCR and Lipoprotein metabolism. GO annotations related to this gene include carboxylic ester hydrolase activity and triglyceride lipase activity. An important paralog of this gene is LPL.
Lipases are esterase enzymes that catalyze the hydrolysis of ester bonds within hydrophobic lipids. The diverse class of lipase enzymes includes diacylglycerol lipase (DAGL) and lipoprotein lipase (LPL) and endothelial lipase (LIPG).