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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PNISR Gene

protein-coding GIFtS: 42
GCID: GC06M099846

PNN-Interacting Serine/Arginine-Rich Protein

(Previous names: chromosome 6 open reading frame 111, splicing factor, arginine/serine-rich...)
(Previous symbols: C6orf111, SFRS18)

Search for PNISR
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
PNN-Interacting Serine/Arginine-Rich Protein¹ ² ³		Chromosome 6 Open Reading Frame 111¹
Splicing Factor, Arginine/Serine-Rich 18¹ ² ³		HSPC306²
C6orf111¹ ² ³		RP11-98I9.2²
SFRS18¹ ² ³		Arginine/Serine-Rich Protein PNISR²
Serine/Arginine-Rich-Splicing Regulatory Protein 130² ³		bA98I9.2²
Splicing Factor, Arginine/Serine-Rich 130² ³		Serine-Arginine-Rich-Splicing Regulatory Protein 130²
SRrp130² ³		SR Rich Protein²
SR-Related Protein² ³		SRRP130³
SR-Rich Protein² ³

External Ids:	HGNC: 21222¹	Entrez Gene: 25957²	Ensembl: ENSG00000132424⁷	UniProtKB: Q8TF01³

Export aliases for PNISR gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PNISR Gene:

PNISR (PNN-interacting serine/arginine-rich protein) is a protein-coding gene.

Gene Wiki entry for PNISR (SFRS18) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NT_025741.15 NC_018917.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for PNISR
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PNISR promoter sequence

Search SABiosciences Chromatin IP Primers for PNISR

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PNISR

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q16.3 Ensembl cytogenetic band: 6q16.2 HGNC cytogenetic band: 6q16.3

PNISR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PNISR gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M099846: view genomic region (about GC identifiers)

Start:	99,845,927 bp from pter	End:	99,873,207 bp from pter
Size:	27,281 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PNISR_HUMAN, Q8TF01 (See protein sequence)

Recommended Name: Arginine/serine-rich protein PNISR

Size: 805 amino acids; 92577 Da

Subunit: Interacts with PNN

Subcellular location: Nucleus speckle

Sequence caution: Sequence=AAH07791.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential

poly-A sequence; Sequence=AAH19074.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential

poly-A sequence; Sequence=AAH52638.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential

poly-A sequence; Sequence=AAH64413.1; Type=Frameshift; Positions=267; Sequence=AAH64640.1; Type=Miscellaneous

discrepancy; Note=Contaminating sequence. Potential poly-A sequence;

Secondary accessions: A8K540 E1P5D2 Q5T064 Q5T065 Q6P2B4 Q6P2N4 Q6PJ93 Q6PK36 Q7Z640 Q8N2L1

Q8TF00 Q96K10 Q96SI3 Q96SM5 Q9P076 Q9P0C0 Q9Y4N3

Alternative splicing: 2 isoforms: Q8TF01-1 Q8TF01-2

Explore the universe of human proteins at neXtProt for PNISR: NX_Q8TF01

Explore proteomics data for PNISR at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q8TF01

PNISR Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (2 alternative transcripts):

NP_056306.1 NP_116259.2

ENSEMBL proteins:

ENSP00000358242 ENSP00000435246 ENSP00000387997

Human Recombinant Protein Products for PNISR:

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	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016607	nuclear speck	IEA	--

PNISR for ontologies About GeneDecksing

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Assay Products for PNISR:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q8TF01

UniProtKB/Swiss-Prot: PNISR_HUMAN, Q8TF01

Similarity: Belongs to the splicing factor SR family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 GenomeRNAi human phenotype for PNISR:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for PNISR

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PNISR

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PNISR

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PNISR

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PNISR
		8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate PNISR (see all 40):
		hsa-miR-323-3p hsa-miR-15a hsa-miR-128 hsa-miR-938 hsa-miR-29b-1* hsa-miR-548l hsa-miR-1276 hsa-miR-424

		SwitchGear 3'UTR luciferase reporter plasmid: PNISR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for PNISR
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PNISR

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PNISR

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for PNISR (Q8TF01³ ENSP00000358242⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PNN	Q9H307³, ENSP00000216832⁴	I2D: score=4 STRING: ENSP00000216832
APC	P25054³, ENSP00000257430⁴	I2D: score=3 STRING: ENSP00000257430
RPS24	ENSP00000414321⁴	STRING: ENSP00000414321

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PNISR

Search CenterWatch for drugs/clinical trials and news about PNISR

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PNISR gene (2 alternative transcripts):

NM_015491.1 NM_032870.2

Unigene Clusters for PNISR:

PNN-interacting serine/arginine-rich protein

Hs.520287 [show with all ESTs], Hs.644863 [show with all ESTs]

Unigene Representative Sequences: NM_032870, AL080186

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000369239(uc003ppo.4 uc011eag.2) ENST00000481229(uc021zdc.1)

ENST00000460600 ENST00000478777(uc003ppr.2) ENST00000476159 ENST00000463021

ENST00000492294 ENST00000498075(uc003ppt.2 uc003pps.2) ENST00000466057

ENST00000438806(uc003ppp.4)

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PNISR
		8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate PNISR (see all 40):
		hsa-miR-323-3p hsa-miR-15a hsa-miR-128 hsa-miR-938 hsa-miR-29b-1* hsa-miR-548l hsa-miR-1276 hsa-miR-424

		SwitchGear 3'UTR luciferase reporter plasmid: PNISR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for PNISR
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PNISR

Clone Products:		OriGene clones in human, mouse for PNISR (see all 11) OriGene ORF clones in mouse, rat for PNISR OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Additional mRNA sequence:

AL080186.1 BC029974.1 BC033061.1

24/36 DOTS entries (see all 36):

DT.455111 DT.100826778 DT.100030918 DT.101984990 DT.99958449 DT.115812 DT.95077869 DT.121316150

DT.100826779 DT.121315834 DT.98131865 DT.91717319 DT.100826769 DT.315004 DT.100030923 DT.100826774

DT.115813 DT.121316112 DT.86851900 DT.121316145 DT.121316165 DT.121316076 DT.100826776 DT.95077851

24/590 AceView cDNA sequences (see all 590):

BF792442 AA876271 AA328912 C01836 AA670150 AI633110 CA942754 AA406520

AW150035 BM875325 W88608 BM698006 AA635011 BM829107 BM548909 AL548204

BQ640130 AA292718 CR623227 AI684188 AA731274 AW082958 AI540119 AI209018

GeneLoc Exon Structure

5/17 Alternative Splicing Database (ASD) splice patterns (SP) for PNISR (see all 17) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	·	6c	^	7a	·	7b	·	7c	·	7d	·	7e	·	7f	^	8a	·	8b	^	9a	·	9b	·	9c	^	10	^
SP1:																			-		-		-		-		-														-
SP2:											-								-		-		-		-		-														-
SP3:											-								-		-		-		-		-														-
SP4:
SP5:							-		-		-								-		-		-		-		-														-

ExUns:	11	^	12	^	13a	·	13b	^	14a	·	14b	^	15
SP1:
SP2:
SP3:
SP4:					-
SP5:

ECgene alternative splicing isoforms for PNISR

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PNISR expression in normal human tissues (normalized intensities) PNISR embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CCATTCTCTT

About this image

PNISR expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/4 selected tissues (see all 4) fully expand


Breast (Uncategorized)
breast epithelium

Umbilical Cord (Extraembryonic Tissues)
Umbilical cord blood-derived endothelial progenitor cells

Endothelium (Cardiovascular System)
Umbilical cord blood-derived endothelial progenitor cells

Epithelium
breast epithelium

See PNISR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PNISR

SOURCE GeneReport for Unigene clusters: Hs.520287 Hs.644863

UniProtKB/Swiss-Prot: PNISR_HUMAN, Q8TF01

Tissue specificity: Expressed in heart, skeletal muscle, thymus, spleen, kidney, liver, placenta and leukocytes

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PNISR

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for PNISR gene from 10/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Sfrs18^{1 , 5}	serine/arginine-rich splicing factor 18^{1, 5}	90.1(n)¹ 92.92(a)¹		4 (9.06 cM)⁵ 66625¹ NM_025669.1¹ NP_079945.1¹ 21847583⁵
chicken (Gallus gallus)	Aves	PNISR¹	PNN-interacting serine/arginine-rich protein	85.64(n) 88.53(a)		421796 NM_001031080.1 NP_001026251.1
lizard (Anolis carolinensis)	Reptilia	PNISR⁶	Uncharacterized protein	77(a)	1 ↔ 1	1(171814889-171847107)
African clawed frog (Xenopus laevis)	Amphibia	Xl.16792²	Xenopus laevis transcribed sequence with weak similarity more	80.19(n)		BU911171.1
zebrafish (Danio rerio)	Actinopterygii	wufb24d01²	Transcribed sequence with weak similarity to protein more	76.1(n)		CK239877.1
fruit fly (Drosophila melanogaster)	Insecta	CG31211¹	CG31211	39.88(n) 31.29(a)		41443 NM_141874.2 NP_650131.1
worm (Caenorhabditis elegans)	Secernentea	rsy-1¹	Protein RSY-1	43.33(n) 34.7(a)		173015 NM_060477.3 NP_492878.2
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	LUC7⁶	Essential protein associated with the U1 snRNP com...	6(a)	1 → many	IV(300214-300999)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT1G70620¹	cyclin-related protein	39.88(n) 28.94(a)		843399 NM_105730.3 NP_177219.2
rice (Oryza sativa)	Liliopsida	Os04g0661700¹	hypothetical protein	42.46(n) 29.11(a)		4337289 NM_001060685.1 NP_001054150.1

ENSEMBL Gene Tree for PNISR (if available)
TreeFam Gene Tree for PNISR (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PNISR gene

2 SIMAP similar genes for PNISR using alignment to 1 protein entry: PNISR_HUMAN:

C6orf111 SFRS18

PNISR for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs62432266^1,2	C,F	--	99847378(+)	`AAAAAT/GTGTTT`	2	--	ds500¹		1		NA	2
rs141488892^1,2		--	99847409(+)	`AGTGGG/TTGACT`	2	--	ds500¹		0	--	--	--	--
rs114703059^1,2	C,F	--	99847444(+)	`TATTAC/ATGTCA`	2	--	ds500¹		1		WA	118
rs145247292^1,2		--	99847459(+)	`CAATCA/GTTCCT`	2	--	ds500¹		0	--	--	--	--
rs137981367^1,2		--	99847535(+)	`CACACA/GTTATA`	2	--	ds500¹		0	--	--	--	--
rs192769223^1,2		--	99847576(+)	`CAAAAC/TAGGAA`	2	--	ds500¹		0	--	--	--	--
rs12191620^1,2	C,F,H	--	99847586(+)	`AGAAAA/TGTTTA`	2	--	ds500¹ trp³		10		NA NS EA	686
rs149494663^1,2		--	99847593(+)	`TTTAGA/GAAGTT`	2	--	ds500¹		0	--	--	--	--
rs1128347^1,2	C,F,A,H	--	99848256(-)	`TTATTT/AAAAAT`	2	--	ut3¹		6		MN NS EA NA	708
rs144779398^1,2		--	99848298(+)	`ACTATA/GATTAT`	2	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for PNISR (99845927 - 99873207 bp)

Structural Variations
Database of Genomic Variants (DGV) 5 variations for PNISR: About this table

Variant ID	Type	Subtype	PubMed ID
nsv527517	CNV	Loss	19592680
nsv823789	CNV	Loss	20364138
nsv886439	CNV	Loss	21882294
nsv886438	CNV	Gain	21882294
nsv886436	CNV	Gain	21882294

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PNISR

DNA2.0 Custom Variant and Variant Library Synthesis for PNISR

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for PNISR gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with PNISR)

Utopia: connect your pdf to the dynamic
world of online information

Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. (PubMed id 14578391)^{1, 2, 3, 9} Zimowska G.... Sugrue S.P. (2003)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)¹ Wang J....Yang X. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
A human MAP kinase interactome. (PubMed id 20936779)¹ Bandyopadhyay S....Ideker T. (2010)
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)² Gauci S....Mohammed S. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 25957	HGNC: 21222	AceView: C6orf111	Ensembl:ENSG00000132424	euGenes: HUgn25957
ECgene: PNISR	H-InvDB: PNISR

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for PNISR	Pharmacogenomics, SNPs, Pathways

Intellectual Property for PNISR gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for PNISR gene:
Search GeneIP for patents involving PNISR

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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PNISR Gene

PNN-Interacting Serine/Arginine-Rich Protein

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PNISR Gene

PNN-Interacting Serine/Arginine-Rich Protein

Aliasesfor PNISR gene

Summariesfor PNISR gene

Genomic Viewsfor PNISR gene

Proteinsfor PNISR gene

Protein Domains /Familiesfor PNISR gene

Functionfor PNISR gene

Pathways & Interactionsfor PNISR gene

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Expression for PNISR gene

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Genomic Variantsfor PNISR gene

Disorders / Diseasesfor PNISR gene

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Genome Databases showing PNISR gene

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Specialized Databases showing PNISR gene

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for PNISR gene

Genomic Views
for PNISR gene

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for PNISR gene

Protein Domains /
Families
for PNISR gene

Function
for PNISR gene

Pathways & Interactions
for PNISR gene

Drugs & Compounds
for PNISR gene

Transcripts
for PNISR gene

Expression
for PNISR gene

Orthologs
for PNISR gene

Paralogs
for PNISR gene

Genomic Variants
for PNISR gene

Disorders / Diseases
for PNISR gene

Publications
for PNISR gene

Intellectual Property
for PNISR gene

Products
for PNISR gene